Download or read book Kernel Ridge Regression in Clinical Research written by Ton J. Cleophas and published by Springer Nature. This book was released on 2022-09-12 with total page 292 pages. Available in PDF, EPUB and Kindle. Book excerpt: IBM (international business machines) has published in its SPSS statistical software 2022 update a very important novel regression method entitled Kernel Ridge Regression (KRR). It is an extension of the currently available regression methods, and is suitable for pattern recognition in high dimensional data, particularly, when alternative methods fail. Its theoretical advantages are plenty and include the kernel trick for reduced arithmetic complexity, estimation of uncertainty by Gaussians unlike histograms, corrected data-overfit by ridge regularization, availability of 8 alternative kernel density models for datafit. A very exciting and wide array of preliminary KRR research has already been published by major disciplines (like studies in quantum mechanics and nuclear physics, studies of molecular affinity / dynamics, atomisation energy studies, but also forecasting economics studies, IoT (internet of things) studies for e-networks, plant stress response studies, big data streaming studies, etc). In contrast, it is virtually unused in clinical research. This edition is the first textbook and tutorial of kernel ridge regressions for medical and healthcare students as well as recollection / update bench, and help desk for professionals. Each chapter can be studied as a standalone, and, using, real as well as hypothesized data, it tests the performance of the novel methodology against traditional regression analyses. Step by step analyses of over 20 data files stored at Supplementary Files at Springer Interlink are included for self-assessment. We should add that the authors are well qualified in their field. Professor Zwinderman is past-president of the International Society of Biostatistics (2012-2015) and Professor Cleophas is past-president of the American College of Angiology (2000-2002). From their expertise they should be able to make adequate selections of modern KRR methods for the benefit of physicians, students, and investigators. The authors have been working and publishing together for 24 years and their research can be characterized as a continued effort to demonstrate that clinical data analysis is not mathematics but rather a discipline at the interface of biology and mathematics.

Download or read book Modern Survival Analysis in Clinical Research written by Ton J. Cleophas and published by Springer Nature. This book was released on 2023-05-29 with total page 230 pages. Available in PDF, EPUB and Kindle. Book excerpt: An important novel menu for Survival Analysis entitled Accelerated Failure Time (AFT) models has been published by IBM (international Businesss Machines) in its SPSS statistical software update of 2023. Unlike the traditional Cox regressions that work with hazards, which are the ratio of deaths and non-deaths in a sample, it works with risk of death, which is the proportion of deaths in the same sample. The latter approach may provide better sensitivity of testing, but has been seldom applied, because with computers risks are tricky and hazards because they are odds are fine. This was underscored in 1997 by Keiding and colleague statisticians from Copenhagen University who showed better-sensitive goodness of fit and null-hypothesis tests with AFT than with Cox survival tests. So far, a controlled study of a representative sample of clinical Kaplan Meier assessments, where the sensitivity of Cox regression is systematically tested against that of AFT modeling, has not been accomplished. This edition is the first textbook and tutorial of AFT modeling both for medical and healthcare students and for professionals. Each chapter can be studied as a standalone, and, using, real as well as hypothesized data, it tests the performance of the novel methodology against traditional Cox regressions. Step by step analyses of over 20 data files stored at Supplementary Files at Springer Interlink are included for self-assessment. We should add that the authors are well qualified in their field. Professor Zwinderman is past-president of the International Society of Biostatistics (2012-2015) and Professor Cleophas is past-president of the American College of Angiology (2000-2002). From their expertise they should be able to make adequate selections of modern data analysis methods for the benefit of physicians, students, and investigators. The authors have been working and publishing together for 25 years and their research can be characterized as a continued effort to demonstrate that clinical data analysis is not mathematics but rather a discipline at the interface of biology and mathematics.

Download or read book Quantile Regression in Clinical Research written by Ton J. Cleophas and published by Springer Nature. This book was released on 2022-01-17 with total page 283 pages. Available in PDF, EPUB and Kindle. Book excerpt: Quantile regression is an approach to data at a loss of homogeneity, for example (1) data with outliers, (2) skewed data like corona - deaths data, (3) data with inconstant variability, (4) big data. In clinical research many examples can be given like circadian phenomena, and diseases where spreading may be dependent on subsets with frailty, low weight, low hygiene, and many forms of lack of healthiness. Stratified analyses is the laborious and rather explorative way of analysis, but quantile analysis is a more fruitful, faster and completer alternative for the purpose. Considering all of this, we are on the verge of a revolution in data analysis. The current edition is the first textbook and tutorial of quantile regressions for medical and healthcare students as well as recollection/update bench, and help desk for professionals. Each chapter can be studied as a standalone and covers one of the many fields in the fast growing world of quantile regressions. Step by step analyses of over 20 data files stored at extras.springer.com are included for self-assessment. We should add that the authors are well qualified in their field. Professor Zwinderman is past-president of the International Society of Biostatistics (2012-2015) and Professor Cleophas is past-president of the American College of Angiology(2000-2002). From their expertise they should be able to make adequate selections of modern quantile regression methods for the benefit of physicians, students, and investigators.

Download or read book Recent Progresses of Non Coding RNAs in Biological and Medical Research 2nd Edition written by Yun Zheng and published by Frontiers Media SA. This book was released on 2020-11-04 with total page 172 pages. Available in PDF, EPUB and Kindle. Book excerpt: Publisher’s note: In this 2nd edition, the following article has been updated: Xun Y, Tang Y, Hu L, Xiao H, Long S, Gong M, Wei C, Wei K and Xiang S (2019) Purification and Identification of miRNA Target Sites in Genome Using DNA Affinity Precipitation. Front. Genet. 10:778. doi: 10.3389/fgene.2019.00778

Download or read book Handbook of Biomedical Imaging written by Nikos Paragios and published by Springer. This book was released on 2015-03-24 with total page 501 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book offers a unique guide to the entire chain of biomedical imaging, explaining how image formation is done, and how the most appropriate algorithms are used to address demands and diagnoses. It is an exceptional tool for radiologists, research scientists, senior undergraduate and graduate students in health sciences and engineering, and university professors.

Download or read book Intelligent Computing Theories and Application written by De-Shuang Huang and published by Springer. This book was released on 2017-07-18 with total page 806 pages. Available in PDF, EPUB and Kindle. Book excerpt: This three-volume set LNCS 10361, LNCS 10362, and LNAI 10363 constitutes the refereed proceedings of the 13th International Conference on Intelligent Computing, ICIC 2017, held in Liverpool, UK, in August 2017. The 212 full papers and 20 short papers of the three proceedings volumes were carefully reviewed and selected from 612 submissions. This first volume of the set comprises 71 papers. The papers are organized in topical sections such as Evolutionary Computation and Learning; Neural Networks; Nature Inspired Computing and Optimization; Signal Processing; Pattern Recognition; Biometrics Recognition; Image Processing; Information Security; Virtual Reality and Human-Computer Interaction; Business Intelligence and Multimedia Technology; Genetic Algorithms; Biomedical Informatics Theory and Methods; Particle Swarm Optimization and Niche Technology; Swarm Intelligence and Optimization; Independent Component Analysis; Compressed Sensing and Sparse Coding; Natural Computing; Intelligent Computing in Computer Vision; Computational Intelligence and Security for Image Applications in Social Network; Neural Networks: Theory and Application.

Download or read book Medical Image Computing and Computer Assisted Intervention MICCAI 2012 written by Nicholas Ayache and published by Springer Science & Business Media. This book was released on 2012-09-22 with total page 807 pages. Available in PDF, EPUB and Kindle. Book excerpt: The three-volume set LNCS 7510, 7511, and 7512 constitutes the refereed proceedings of the 15th International Conference on Medical Image Computing and Computer-Assisted Intervention, MICCAI 2012, held in Nice, France, in October 2012. Based on rigorous peer reviews, the program committee carefully selected 252 revised papers from 781 submissions for presentation in three volumes. The first volume includes 91 papers organized in topical sections on abdominal imaging, computer-assisted interventions and robotics; computer-aided diagnosis and planning; image reconstruction and enhancement; analysis of microscopic and optical images; computer-assisted interventions and robotics; image segmentation; cardiovascular imaging; and brain imaging: structure, function and disease evolution.

Download or read book Advanced Network Technologies and Intelligent Computing written by Isaac Woungang and published by Springer Nature. This book was released on 2023-03-21 with total page 693 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book constitutes the refereed proceedings of the Second International Conference on Advanced Network Technologies and Intelligent Computing, ANTIC 2022, held in Varanasi, India, during December 22–24, 2022. The 68 full papers and 11 short papers included in this book were carefully reviewed and selected from 443 submissions. They were organized in two topical sections as follows: Advanced Network Technologies and Intelligent Computing.

Download or read book Applications of Big Data in Healthcare written by Ashish Khanna and published by Academic Press. This book was released on 2021-03-10 with total page 311 pages. Available in PDF, EPUB and Kindle. Book excerpt: Applications of Big Data in Healthcare: Theory and Practice begins with the basics of Big Data analysis and introduces the tools, processes and procedures associated with Big Data analytics. The book unites healthcare with Big Data analysis and uses the advantages of the latter to solve the problems faced by the former. The authors present the challenges faced by the healthcare industry, including capturing, storing, searching, sharing and analyzing data. This book illustrates the challenges in the applications of Big Data and suggests ways to overcome them, with a primary emphasis on data repositories, challenges, and concepts for data scientists, engineers and clinicians. The applications of Big Data have grown tremendously within the past few years and its growth can not only be attributed to its competence to handle large data streams but also to its abilities to find insights from complex, noisy, heterogeneous, longitudinal and voluminous data. The main objectives of Big Data in the healthcare sector is to come up with ways to provide personalized healthcare to patients by taking into account the enormous amounts of already existing data. - Provides case studies that illustrate the business processes underlying the use of big data and deep learning health analytics to improve health care delivery - Supplies readers with a foundation for further specialized study in clinical analysis and data management - Includes links to websites, videos, articles and other online content to expand and support the primary learning objectives for each major section of the book

Download or read book Computational Epigenetics in Human Diseases Cell Differentiation and Cell Reprogramming Volume I written by Jianzhong Su and published by Frontiers Media SA. This book was released on 2021-02-24 with total page 465 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Regression Methods for Medical Research written by Bee Choo Tai and published by John Wiley & Sons. This book was released on 2013-10-09 with total page 388 pages. Available in PDF, EPUB and Kindle. Book excerpt: Regression Methods for Medical Research provides medical researchers with the skills they need to critically read and interpret research using more advanced statistical methods. The statistical requirements of interpreting and publishing in medical journals, together with rapid changes in science and technology, increasingly demands an understanding of more complex and sophisticated analytic procedures. The text explains the application of statistical models to a wide variety of practical medical investigative studies and clinical trials. Regression methods are used to appropriately answer the key design questions posed and in so doing take due account of any effects of potentially influencing co-variables. It begins with a revision of basic statistical concepts, followed by a gentle introduction to the principles of statistical modelling. The various methods of modelling are covered in a non-technical manner so that the principles can be more easily applied in everyday practice. A chapter contrasting regression modelling with a regression tree approach is included. The emphasis is on the understanding and the application of concepts and methods. Data drawn from published studies are used to exemplify statistical concepts throughout. Regression Methods for Medical Research is especially designed for clinicians, public health and environmental health professionals, para-medical research professionals, scientists, laboratory-based researchers and students.

Download or read book XIV Mediterranean Conference on Medical and Biological Engineering and Computing 2016 written by Efthyvoulos Kyriacou and published by Springer. This book was released on 2016-03-31 with total page 1384 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume presents the proceedings of Medicon 2016, held in Paphos, Cyprus. Medicon 2016 is the XIV in the series of regional meetings of the International Federation of Medical and Biological Engineering (IFMBE) in the Mediterranean. The goal of Medicon 2016 is to provide updated information on the state of the art on Medical and Biological Engineering and Computing under the main theme “Systems Medicine for the Delivery of Better Healthcare Services”. Medical and Biological Engineering and Computing cover complementary disciplines that hold great promise for the advancement of research and development in complex medical and biological systems. Research and development in these areas are impacting the science and technology by advancing fundamental concepts in translational medicine, by helping us understand human physiology and function at multiple levels, by improving tools and techniques for the detection, prevention and treatment of disease. Medicon 2016 provides a common platform for the cross fertilization of ideas, and to help shape knowledge and scientific achievements by bridging complementary disciplines into an interactive and attractive forum under the special theme of the conference that is Systems Medicine for the Delivery of Better Healthcare Services. The programme consists of some 290 invited and submitted papers on new developments around the Conference theme, presented in 3 plenary sessions, 29 parallel scientific sessions and 12 special sessions.

Download or read book Information Processing in Medical Imaging written by Albert C. S. Chung and published by Springer. This book was released on 2019-05-22 with total page 884 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book constitutes the proceedings of the 26th International Conference on Information Processing in Medical Imaging, IPMI 2019, held at the Hong Kong University of Science and Technology, Hong Kong, China, in June 2019. The 69 full papers presented in this volume were carefully reviewed and selected from 229 submissions. They were organized in topical sections on deep learning and segmentation; classification and inference; reconstruction; disease modeling; shape, registration; learning motion; functional imaging; and white matter imaging. The book also includes a number of post papers.

Download or read book Theory of Ridge Regression Estimation with Applications written by A. K. Md. Ehsanes Saleh and published by John Wiley & Sons. This book was released on 2019-02-12 with total page 384 pages. Available in PDF, EPUB and Kindle. Book excerpt: A guide to the systematic analytical results for ridge, LASSO, preliminary test, and Stein-type estimators with applications Theory of Ridge Regression Estimation with Applications offers a comprehensive guide to the theory and methods of estimation. Ridge regression and LASSO are at the center of all penalty estimators in a range of standard models that are used in many applied statistical analyses. Written by noted experts in the field, the book contains a thorough introduction to penalty and shrinkage estimation and explores the role that ridge, LASSO, and logistic regression play in the computer intensive area of neural network and big data analysis. Designed to be accessible, the book presents detailed coverage of the basic terminology related to various models such as the location and simple linear models, normal and rank theory-based ridge, LASSO, preliminary test and Stein-type estimators. The authors also include problem sets to enhance learning. This book is a volume in the Wiley Series in Probability and Statistics series that provides essential and invaluable reading for all statisticians. This important resource: Offers theoretical coverage and computer-intensive applications of the procedures presented Contains solutions and alternate methods for prediction accuracy and selecting model procedures Presents the first book to focus on ridge regression and unifies past research with current methodology Uses R throughout the text and includes a companion website containing convenient data sets Written for graduate students, practitioners, and researchers in various fields of science, Theory of Ridge Regression Estimation with Applications is an authoritative guide to the theory and methodology of statistical estimation.

Download or read book Algorithmic Learning in a Random World written by Vladimir Vovk and published by Springer Science & Business Media. This book was released on 2005-03-22 with total page 344 pages. Available in PDF, EPUB and Kindle. Book excerpt: Algorithmic Learning in a Random World describes recent theoretical and experimental developments in building computable approximations to Kolmogorov's algorithmic notion of randomness. Based on these approximations, a new set of machine learning algorithms have been developed that can be used to make predictions and to estimate their confidence and credibility in high-dimensional spaces under the usual assumption that the data are independent and identically distributed (assumption of randomness). Another aim of this unique monograph is to outline some limits of predictions: The approach based on algorithmic theory of randomness allows for the proof of impossibility of prediction in certain situations. The book describes how several important machine learning problems, such as density estimation in high-dimensional spaces, cannot be solved if the only assumption is randomness.

Download or read book Medical Image Computing and Computer Assisted Intervention MICCAI 2011 written by Gabor Fichtinger and published by Springer Science & Business Media. This book was released on 2011-09-02 with total page 726 pages. Available in PDF, EPUB and Kindle. Book excerpt: The three-volume set LNCS 6891, 6892 and 6893 constitutes the refereed proceedings of the 14th International Conference on Medical Image Computing and Computer-Assisted Intervention, MICCAI 2011, held in Toronto, Canada, in September 2011. Based on rigorous peer reviews, the program committee carefully selected 251 revised papers from 819 submissions for presentation in three volumes. The second volume includes 83 papers organized in topical sections on diffusion weighted imaging, fMRI, statistical analysis and shape modeling, and registration.

Download or read book Artificial Intelligence Techniques in IoT Sensor Networks written by Mohamed Elhoseny and published by CRC Press. This book was released on 2020-12-22 with total page 232 pages. Available in PDF, EPUB and Kindle. Book excerpt: Artificial Intelligence Techniques in IoT Sensor Networks is a technical book which can be read by researchers, academicians, students and professionals interested in artificial intelligence (AI), sensor networks and Internet of Things (IoT). This book is intended to develop a shared understanding of applications of AI techniques in the present and near term. The book maps the technical impacts of AI technologies, applications and their implications on the design of solutions for sensor networks. This text introduces researchers and aspiring academicians to the latest developments and trends in AI applications for sensor networks in a clear and well-organized manner. It is mainly useful for research scholars in sensor networks and AI techniques. In addition, professionals and practitioners working on the design of real-time applications for sensor networks may benefit directly from this book. Moreover, graduate and master’s students of any departments related to AI, IoT and sensor networks can find this book fascinating for developing expert systems or real-time applications. This book is written in a simple and easy language, discussing the fundamentals, which relieves the requirement of having early backgrounds in the field. From this expectation and experience, many libraries will be interested in owning copies of this work.