Download or read book Molecular Biology of the Cell written by and published by . This book was released on 2002 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book PRINS and PNA Technologies in Chromosomal Investigations written by Franck Pellestor and published by Nova Publishers. This book was released on 2007 with total page 208 pages. Available in PDF, EPUB and Kindle. Book excerpt: Book & CD. Advances in molecular biotechnology have greatly improved the sensitivity and the efficiency of methods utilised for genetic investigations and diagnosis. In the domain of chromosome analysis, the introduction of molecular techniques has led to the development of a new approach, called Molecular Cytogenetics, which has surpassed previously available techniques to become a foremost biological method. The fluorescence in situ hybridisation (FISH) is quickly became the standard technique for in situ chromosomal investigations, as illustrated by its large variety of applications in research and diagnosis. However, during the last decade, alternative methods to FISH have been introduced and have shown to be valuable in detecting chromosomes and quantifying chromosomal abnormalities. These alternative procedures are the Primed IN Situ (PRINS) labelling and the Peptide Nucleic Acid (PNA) probes. The two procedures present several advantages for the in situ detection of nucleic acid sequences, such as the small size of PNA probes and PRINS primers, or the fast kinetics of PRINS and PNA labelling reactions, that make them very attractive for a number of cytogenetic purposes. This book provides a valuable introduction and overview of the principles and the applications of alternative approaches in the field of molecular cytogenetics.

Download or read book Childhood Acute Lymphoblastic Leukemia written by Ajay Vora and published by Springer. This book was released on 2017-04-21 with total page 345 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book provides a comprehensive and up-to-date review of all aspects of childhood Acute Lymphoblastic Leukemia, from basic biology to supportive care. It offers new insights into the genetic pre-disposition to the condition and discusses how response to early therapy and its basic biology are utilized to develop new prognostic stratification systems and target therapy. Readers will learn about current treatment and outcomes, such as immunotherapy and targeted therapy approaches. Supportive care and management of the condition in resource poor countries are also discussed in detail. This is an indispensable guide for research and laboratory scientists, pediatric hematologists as well as specialist nurses involved in the care of childhood leukemia.

Download or read book Screening for Down s Syndrome written by J. G. Grudzinskas and published by Cambridge University Press. This book was released on 1994-11-17 with total page 364 pages. Available in PDF, EPUB and Kindle. Book excerpt: This important new publication summarises the recent exciting advances in screening for Down's syndrome. It addresses important clinical questions such as: risk assessment, who to screen, when to screen, which techniques to use, and the organisation of screening programmes nationally and internationally. An international and authoritative team of authors has been invited to assess the latest developments in this rapidly advancing area. The volume provides a critical and much needed evaluation of the potential and limitations of new and established techniques for screening for Down's syndrome. It will serve as an essential source of information for all those involved in pre-natal diagnosis and the provision of obstetric care.

Download or read book BSCS Science Technology Investigating Life Systems Teacher Edition written by and published by Kendall Hunt. This book was released on 2005 with total page 656 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book The Philadelphia Chromosome A Genetic Mystery a Lethal Cancer and the Improbable Invention of a Lifesaving Treatment written by Jessica Wapner and published by The Experiment, LLC. This book was released on 2014-04-08 with total page 345 pages. Available in PDF, EPUB and Kindle. Book excerpt: One of The Wall Street Journal’s 10 Best Nonfiction Books of the Year Philadelphia, 1959: A scientist scrutinizing a single human cell under a microscope detects a missing piece of DNA. That scientist, David Hungerford, had no way of knowing that he had stumbled upon the starting point of modern cancer research— the Philadelphia chromosome. It would take doctors and researchers around the world more than three decades to unravel the implications of this landmark discovery. In 1990, the Philadelphia chromosome was recognized as the sole cause of a deadly blood cancer, chronic myeloid leukemia, or CML. Cancer research would never be the same. Science journalist Jessica Wapner reconstructs more than forty years of crucial breakthroughs, clearly explains the science behind them, and pays tribute—with extensive original reporting, including more than thirty-five interviews—to the dozens of researchers, doctors, and patients with a direct role in this inspirational story. Their curiosity and determination would ultimately lead to a lifesaving treatment unlike anything before it. The Philadelphia Chromosome chronicles the remarkable change of fortune for the more than 70,000 people worldwide who are diagnosed with CML each year. It is a celebration of a rare triumph in the battle against cancer and a blueprint for future research, as doctors and scientists race to uncover and treat the genetic roots of a wide range of cancers.

Download or read book Chemical Mutagens written by and published by . This book was released on 1971 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Chromosome 6 written by Robin Cook and published by Penguin. This book was released on 1998-04-01 with total page 484 pages. Available in PDF, EPUB and Kindle. Book excerpt: “Master of the medical thriller.”—The New York Times In his most prophetic thriller yet, Robin Cook goes behind the headlines on cloning and genetic manipulation, blending fact with fiction in this terrifying bestseller. In the jungles of equatorial Africa, a biotechnology giant has taken transplant surgery and animal research to a new level—where one mistake could bridge the evolutionary gap between man and ape and forever change the genetic map of our existence. Meanwhile, in New York City, Jack Stapleton and Laurie Montgomery are working on a seemingly unrelated murder of a mobster, only to find some very odd things once their victim is on the autopsy table...

Download or read book Cellular Transforming Genes written by and published by . This book was released on 1986 with total page 4 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Adam s Curse written by Bryan Sykes and published by W. W. Norton & Company. This book was released on 2004 with total page 336 pages. Available in PDF, EPUB and Kindle. Book excerpt: Examines the history and future of the Y chromosome and maintains that because it is unable to exchange genetic material or repair itself, the day will come when it will cease to exist.

Download or read book WHO Laboratory Manual for the Examination of Human Semen and Sperm Cervical Mucus Interaction written by World Health Organisation and published by Cambridge University Press. This book was released on 1999-05-13 with total page 150 pages. Available in PDF, EPUB and Kindle. Book excerpt: The definitive and essential source of reference for all laboratories involved in the analysis of human semen.

Download or read book Evolution of Translational Omics written by Institute of Medicine and published by National Academies Press. This book was released on 2012-09-13 with total page 354 pages. Available in PDF, EPUB and Kindle. Book excerpt: Technologies collectively called omics enable simultaneous measurement of an enormous number of biomolecules; for example, genomics investigates thousands of DNA sequences, and proteomics examines large numbers of proteins. Scientists are using these technologies to develop innovative tests to detect disease and to predict a patient's likelihood of responding to specific drugs. Following a recent case involving premature use of omics-based tests in cancer clinical trials at Duke University, the NCI requested that the IOM establish a committee to recommend ways to strengthen omics-based test development and evaluation. This report identifies best practices to enhance development, evaluation, and translation of omics-based tests while simultaneously reinforcing steps to ensure that these tests are appropriately assessed for scientific validity before they are used to guide patient treatment in clinical trials.

Download or read book One Hundred Years of Chromosome Research and What Remains to be Learned written by A. Lima-de-Faria and published by Springer Science & Business Media. This book was released on 2013-06-29 with total page 196 pages. Available in PDF, EPUB and Kindle. Book excerpt: One Hundred Years of Chromosome Research: What Remains to be Learned, offers the reader a critical analysis of the observations and experiments that shaped the last 100 years of chromosome research, as well as the ideas which prevailed during this period. Emphasis is placed on what remains to be learned, particularly in light of reality of the sequencing of DNA which leaves the previous era of chromosome research as a prehistoric event. It is at this turning point, that well formulated questions can be asked about many of the chromosome's properties, which remain to be unveiled. The author, Lima-de-Faria is Professor Emeritus of Molecular Cytogenetics at Lund Unviersity, Sweden, previously Head of the Institute of Molecular Cytogenetics, Lund University.

Download or read book Hearings written by United States. Congress Senate and published by . This book was released on 1964 with total page 2566 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Health Effects of Exposure to Low Levels of Ionizing Radiation written by National Research Council and published by National Academies. This book was released on 1990-02-01 with total page 436 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book reevaluates the health risks of ionizing radiation in light of data that have become available since the 1980 report on this subject was published. The data include new, much more reliable dose estimates for the A-bomb survivors, the results of an additional 14 years of follow-up of the survivors for cancer mortality, recent results of follow-up studies of persons irradiated for medical purposes, and results of relevant experiments with laboratory animals and cultured cells. It analyzes the data in terms of risk estimates for specific organs in relation to dose and time after exposure, and compares radiation effects between Japanese and Western populations.

Download or read book A Study of the Chromosomes of the Germ Cells of Metazoa written by Thomas Harrison Montgomery and published by . This book was released on 1901 with total page 116 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book SCIENCE TOPIC WISE written by RP. Manchanda and published by Rachna Sagar Private Limited. This book was released on with total page 544 pages. Available in PDF, EPUB and Kindle. Book excerpt: Together with’ CBSE Question Bank Class 10 Science Board Exam 2025 has been prepared as per the CBSE latest syllabus for Board Examinations for Academic Session 2024-25. Chapter wise/Topic-wise Question Bank provides in depth knowledge of concept based questions and their weightage to prepare for Class 10th CBSE Science Board Exam 2025.The question bank highlights the Knowledge based and Skill-based questions to prepare the subject in depth. Salient Features: ‘Together with’ CBSE Science Question Bank based on latest syllabus CBSE Books Class 10 comprises Chapter-wise Flow Charts and NCERT based Activities The chapter has been divided Topic-Wise as per NCERT topics. Solved Question Bank Science for Board Exams 2024-25 includes MCQs, Short/Long Answer Type, NCERT Exemplar Questions Science Question Bank 10 includes CBSE Practice Questions Class 10 CBSE reference book also includes MCQs, including Competency based and High Order Thinking Skill (HOTS) Questions Latest CBSE Syllabus and NCERT Textbooks based Question Bank Including (Intext and Exercises) Exam Oriented Prep Tools CBSE Practice Papers Self-Evaluation test questions CBSE latest examination paper