Download or read book Intrinsic Healing in the Equine Superficial Digital Flexor Tendon in Vitro written by Jeremy V. Bailey and published by . This book was released on 2000 with total page 23 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Intrinsic Healing in the Equine Superficial Digital Flexor Tendon i in Vitro i written by and published by . This book was released on 1901 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book The equine superficial digital flexor tendon the influences of exercise on early development and of diathermy on tendon healing written by Worakij Cherdchutham and published by . This book was released on 2001 with total page 160 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Healing of Surgically Created Defects in the Equine Superficial Digital Flexor Tendon written by Jeffrey Paul Watkins and published by . This book was released on 1984 with total page 172 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Studies on the Effects of Insulin like Growth Factor I on Tendon Metabolism and Intrinsic Tendon Repair written by David John Murphy and published by . This book was released on 1996 with total page 198 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book In Vitro Evaluation of Therapeutic Laser Treatment on Equine Tendon Fibroblasts written by Kirsty A. Husby and published by . This book was released on 2016 with total page 113 pages. Available in PDF, EPUB and Kindle. Book excerpt: Previous investigations have failed to show benefits of low level laser therapy (LLLT) for tendon healing in horses, contrary to reports in other species. We hypothesized that delivery of LLLT at manufacturer-recommended energy fluence through equine cadaver skin to equine tendon-derived fibroblasts in vitro would increase cell proliferation, metabolic activity and migration. Fibroblasts from grossly normal front superficial digital flexor tendons of four horses euthanatized for reasons unrelated to the study were cultured in monolayer. Cells were treated through one of three equine cadaver skin samples (light, medium, or dark colored) at manufacturer-recommended energy fluence. Untreated cells served as controls. At 24 hours after treatment, cell proliferation was determined via manual cell counts and cellular metabolic rate was assessed via resazurin sodium salt reduction assay. Cell migration was determined by scratch assay and by transwell migration assay. Data was analyzed by repeated measures ANOVA with p
Download or read book The in Vitro Biomechanical Properties of Equine Forelimb Superficial Digital Flexor Tendons written by Bradley A. Dowling and published by . This book was released on 1999 with total page 212 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Evaluation and Optimization of a Three dimensional Construct Model for Equine Superficial Digital Flexor Tendon written by Monica Yvette Pechanec and published by . This book was released on 2017 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt: Musculoskeletal injuries in equine athletes represent one of the leading causes for sport-induced and career-ending injuries due to slow or incomplete tendon repair creating clinical challenges in functional repair and effective rehabilitation. As ideal strategies for tendon repair are being developed, testing these treatments begins with models. Three-dimensional (3D) tendon constructs provide an in vitro model highly representative of in vivo tendon. For some model species, protocols for cell seeding have been established, yet this is not the case for horse cells. Using a mouse 3D construct protocol with horse superficial digital flexor tendon (SDFT) cells led us to consider the need for protocol optimization for the horse cells. High cellularity in a construct could be advantageous due to the greater amount of cellular machinery for collagen production; however, more cells may produce spatial constraints thereby limiting area for collagen deposition. A balance between cell number and spatial constraint is necessary. Additionally, seeding technique – either by spreading the matrix or localizing – may affect mechanical or material properties due to differences in fibrinogen processing, collagen production and alignment. Biochemical, collagen content, and fibril ultrastructure organization analysis conducted on varying cell seeding concentrations (100,000, 300,000, and 500,000) showed that although not significant 300,000 cells per construct produced a more functionally and structurally reproducible construct. Assessing biomechanical and collagen content analysis for two seeding methods – local and spread – the localized method proved to be statistically stronger and more representative of in vivo tendon. Collectively, our findings show evidence that although cell seeding number does not ultimately affect the construct, the cell seeding method for three-dimensional constructs does affect the overall structure and function of the model tendon.
Download or read book Acoustoelastographic Analysis of Tendon Ultrasound Images and Its Application to Management of Equine Tendon Strain Injury written by Sabrina Helen Brounts and published by . This book was released on 2018 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Superficial digital flexor tendon injury is common in athletic horses. Recovery requires balancing rest and controlled exercise, resulting in high risk of reinjury. It is difficult to determine the level of work the damaged tissue can sustain based on serial ultrasound examination alone. Because small changes in sonographic appearance are associated with large changes in biomechanical strength, it is difficult to accurately determine the degree of loading an injured tendon can sustain. Acoustoelastography (AEG), is a new ultrasound-based tissue property evaluation technique for tendons. AEG determines stiffness gradient, the rate of change of normalized stiffness as a function of strain, by analyzing the changes in echo intensity observed in cine loops captured from gradually deforming tendon. Further, stiffness generally correlates with strength, so stiffness changes provide a useful functional metric. The central hypothesis of this dissertation is that AEG is able to detect differences in stiffness between normal and injured equine SDFT in-vitro and in-vivo. The studies presented in this dissertation demonstrate that the elastic strain limit, in the equine SDFT is ~6%. AEG can detect changes in biomechanical properties in-vitro once damage has occurred. AEG can be applied in-vivo to measure stiffness in SDFT's in clinically normal horses. AEG measurement by a novice operators is as reliable as measurement by an experienced operator. However, sedation of the horse does affect AEG; therefore, the sedation regimen needs to be consistent during serial examination of a patient. Finally, we demonstrated that AEG is able to detect the loss in stiffness in equine SDFT associated with injury with 91.9% sensitivity and 81.6% specificity. In addition, AEG is also able to identify increases in stiffness during healing. This dissertation suggests that AEG is a promising new imaging technology that can be used for the non-invasive evaluation of equine SDFT injury. Use of AEG can improve detection, monitoring and treatment of tendon injury and may ultimately shorten healing time. The findings of this dissertation will be used as the bases for future research and clinical studies to refine the technology and to investigate the use of AEG in other tendons.
Download or read book Tendon Injuries written by Nicola Maffulli and published by Springer Science & Business Media. This book was released on 2005-02-09 with total page 372 pages. Available in PDF, EPUB and Kindle. Book excerpt: Tendon ailments are a significant cause of morbidity among athletes of all levels and are increasing in prevalence. Their management is often empirical, and para-scientific, only looking at the biological aspects of tendon ailments. This book conveys a comprehensive and concise body of knowledge on the management of tendon problems in sportspeople with practical details of clinical protocols. Tendon Injuries: Basic Science and Clinical Medicine is specifically dedicated to the clinical aspects of tendinopathy and provides the required knowledge and scientific basis for the sports medicine practitioner, orthopedic specialist and student facing upper and lower limb tendon ailments in athletes. A comprehensive review of tendon disorders is given and modern criteria of management outlined to form the basis of effective clinical management of this group of patients.
Download or read book Tendon Regeneration written by Manuela E. Gomes and published by Academic Press. This book was released on 2015-08-08 with total page 471 pages. Available in PDF, EPUB and Kindle. Book excerpt: Tendon Regeneration: Understanding Tissue Physiology and Development to Engineer Functional Substitutes is the first book to highlight the multi-disciplinary nature of this specialized field and the importance of collaboration between medical and engineering laboratories in the development of tissue-oriented products for tissue engineering and regenerative medicine (TERM) strategies. Beginning with a foundation in developmental biology, the book explores physiology, pathology, and surgical reconstruction, providing guidance on biological approaches that enhances tendon regeneration practices. Contributions from scientists, clinicians, and engineers who are the leading figures in their respective fields present recent findings in tendon stem cells, cell therapies, and scaffold treatments, as well as examples of pre-clinical models for translational therapies and a view of the future of the field. - Provides an overview of tendon biology, disease, and tissue engineering approaches - Presents modern, alternative approaches to developing functional tissue solutions discussed - Includes valuable information for those interested in tissue engineering, tissue regeneration, tissue physiology, and regenerative medicine - Explores physiology, pathology, and surgical reconstruction, building a natural progression that enhances tendon regeneration practices - Covers recent findings in tendon stem cells, cell therapies, and scaffold treatments, as well as examples of pre-clinical models for translational therapies and a view of the future of the field
Download or read book American Journal of Veterinary Research written by and published by . This book was released on 2012 with total page 596 pages. Available in PDF, EPUB and Kindle. Book excerpt: Volumes for 1956- include selected papers from the proceedings of the American Veterinary Medical Association.
Download or read book The Soft Hard Tissue Junction written by Neil D. Broom and published by Cambridge University Press. This book was released on 2018-11-29 with total page 810 pages. Available in PDF, EPUB and Kindle. Book excerpt: Richly illustrated throughout with actual tissue images, this innovative book shows that the soft-hard tissue junction is best understood in a biomechanical context. The authors describe their pioneering experimental methods, providing an essential structure-function framework for computational modelling, and thereby encouraging the development of more realistic, predictive models of this important tissue junction. Covering the three main musculoskeletal junctions of cartilage-bone, disc-vertebra, and ligament/tendon-bone, the relevant soft tissues are examined with respect to both their own inherent structure and their mode of integration with the hard tissue. The soft-hard tissue interface is explored with a focus on structural damage resulting from overloading, and its associated pathologies. Adopting a multiscale approach, ranging in structural resolution from the macro to fibril levels, this is a must-have guide to the field and an ideal resource for researchers seeking new and creative approaches for studying the joint and spine tissues.
Download or read book Joint Disease in the Horse written by C. Wayne McIlwraith and published by Elsevier Health Sciences. This book was released on 2015-09-23 with total page 425 pages. Available in PDF, EPUB and Kindle. Book excerpt: Dr. McIlwraith's Joint Disease in the Horse, 2nd Edition is the only book to give you a full account of equine joint disease, combining a thorough, up-to-date survey of scientific advances with a practical guide to both medical and surgical treatments. With contributions from nationally and internationally recognized pioneers in the field, this groundbreaking text offers an overview of joint structure and function and translates the latest information on basic joint pathobiology into practical application for the clinician. Step-by-step guidance on injection techniques and medications, along with a survey of practical arthroscopic surgery and developments, make it a truly indispensable reference for all equine veterinarians treating sports and racing horses. UNIQUE! Unprecedented, state-of-the-art coverage of the pathology, pathogenesis, and clinical diagnosis of traumatic and degenerative joint disease, so you stay in the know. Section on general principles of joint pathobiology provides the background to evaluate and interpret the diagnostic and surgical aspects of disease. Explores treatments for traumatic arthritis and osteoarthritis and other joint entities, offering a broad range of options and up-to-date recommendations for problematic decisions. Addresses recent advances and results in arthroscopic surgery for the acute injury and results including fragment removal, fragment fixation, and synovectomy. Discussion of current research provides insight for difficult cases and calls out the directions in which future arthritis research is headed. More than 325 photographs and line drawings help engage and guide you through procedures and treatments. NEW! Full color throughout with new artwork and a range of new images including radiographs showing both the normal and the disease progression. NEW! Practical step-by-step approach demonstrates the authors' preferred injections methods and shows underlying anatomic correlations. NEW and UPDATED! Restructured and substantially revised to emphasize treatment options, making it a practical, concise, and accessible reference and text. NEW! All-new chapters on drugs and new biological therapies, including stem cells, IRAP, and PRP and thoroughly updated coverage of HA and corticosteroids. NEW! Covers advanced imaging, giving you the latest information available. NEW! Expert advice from Dr. McIlwraith, three new co-editors, and new contributors - all distinguished specialists in the field of joint disease in the horse. Lameness and surgical clinicians describe how to approach the various, specific disease conditions. Equine specific radiologists provide their opinions on the best imaging techniques for defining the disease and making interpretations.
Download or read book Cell Engineering and Regeneration written by Heinz Redl and published by Springer. This book was released on 2017-02-16 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: This reference work presents the origins of cells for tissue engineering and regeneration, including primary cells, tissue-specific stem cells, pluripotent stem cells and trans-differentiated or reprogrammed cells. There is particular emphasis on current understanding of tissue regeneration based on embryology and evolution studies, including mechanisms of amphibian regeneration. The book covers the use of autologous versus allogeneic cell sources, as well as various procedures used for cell isolation and cell pre-conditioning , such as cell sorting, biochemical and biophysical pre-conditioning, transfection and aggregation. It also presents cell modulation using growth factors, molecular factors, epigenetic approaches, changes in biophysical environment, cellular co-culture and other elements of the cellular microenvironment. The pathways of cell delivery are discussed with respect to specific clinical situations, including delivery of ex vivo manipulated cells via local and systemic routes, as well as activation and migration of endogenous reservoirs of reparative cells. The volume concludes with an in-depth discussion of the tracking of cells in vivo and their various regenerative activities inside the body, including differentiation, new tissue formation and actions on other cells by direct cell-to-cell communication and by secretion of biomolecules.
Download or read book Adams and Stashak s Lameness in Horses written by Gary M. Baxter and published by John Wiley & Sons. This book was released on 2011-06-28 with total page 1280 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Sixth Edition of Adams and Stashak’s Lameness in Horses builds on the book’s reputation as the classic gold-standard reference on equine lameness. Now in full color, the text has been fully revised and streamlined to improve user-friendliness, with a new, simplified format and a stronger emphasis on the diagnosis and management of lameness. A valuable supplementary DVD provides a complete guide to diagnosing lameness, offering additional anatomical images; video clips demonstrating key procedures such as physical examination, flexion tests, perineural and intrasynovial anesthesia; and examples of lameness conditions in motion. The Sixth Edition presents new or significantly rewritten chapters on the axial skeleton, principles of musculoskeletal disease, principles of therapy for lameness, occupation-related lameness conditions, and lameness in the young horse. The diagnostic procedures chapter has also been significantly expanded to reflect advances in this important area. Adams and Stashak’s Lameness in Horses, Sixth Edition is an essential addition to any equine practitioner’s bookshelf.
Download or read book Equine Surgery E Book written by Jorg A. Auer and published by Elsevier Health Sciences. This book was released on 2018-05-24 with total page 1898 pages. Available in PDF, EPUB and Kindle. Book excerpt: **Selected for Doody's Core Titles® 2024 with "Essential Purchase" designation in Veterinary Medicine** Equip yourself for success with the only book on the market that covers all aspects of equine surgery! Equine Surgery, 5th Edition prepares you to manage each surgical condition by understanding its pathophysiology and evaluating alternative surgical approaches. Explanations in the book describe how to avoid surgical infections, select and use instruments, and perfect fundamental surgical techniques including incisions, cautery, retractions, irrigation, surgical suction, wound closure, dressings, bandages, and casts. In addition to diagnostic imaging and orthopedic coverage, it includes in-depth information on anesthesia, the integumentary system (including wound management, reconstructive surgery, and skin grafting), the alimentary system, respiratory, and urogenital systems. - Complete coverage of all the information needed to study for the American and European College of Veterinary Surgeons Board Examinations makes this edition an excellent study tool. - Section on anesthesiology and pain management prepares you to manage these critical aspects of any surgery. - Extensive, up-to-date orthopedic coverage includes joint disorders and joint trauma. - Section on integumentary system contains information on wound management, reconstructive surgery, and skin grafting. - Section on the alimentary system covers postoperative care, complications and reoperation guidelines. - New techniques in vascular surgery keep you up-to-date with best practices. - NEW! Expert Consult site offering 40+ videos of surgeons performing techniques so that you can quickly access drug and equipment information. - NEW! Expansion of minimally invasive surgical techniques includes laser ablation procedures, implantation of plates against bones in orthopedic procedures, and laparoscopic procedures for soft tissue injuries. - NEW! World-renowned contributors, featuring two new associate editors include over 70 of the most experienced and expert equine specialist surgeons, each providing current and accurate information. - NEW! Current advances in imaging detect musculoskeletal conditions in the sports horse.
