Download or read book Neural Microelectrodes Design and Applications written by Stuart Cogan and published by . This book was released on 2019 with total page 1 pages. Available in PDF, EPUB and Kindle. Book excerpt: Neural electrodes enable the recording and stimulation of bioelectrical activity in the nervous system. This technology provides neuroscientists with the means to probe the functionality of neural circuitry in both health and disease. In addition, neural electrodes can deliver therapeutic stimulation for the relief of debilitating symptoms associated with neurological disorders such as Parkinson's disease and may serve as the basis for the restoration of sensory perception through peripheral nerve and brain regions after disease or injury. Lastly, microscale neural electrodes recording signals associated with volitional movement in paralyzed individuals can be decoded for controlling external devices and prosthetic limbs or driving the stimulation of paralyzed muscles for functional movements. In spite of the promise of neural electrodes for a range of applications, chronic performance remains a goal for long-term basic science studies, as well as clinical applications. New perspectives and opportunities from fields including tissue biomechanics, materials science, and biological mechanisms of inflammation and neurodegeneration are critical to advances in neural electrode technology. This Special Issue will address the state-of-the-art knowledge and emerging opportunities for the development and demonstration of advanced neural electrodes.
Download or read book Neural Interface Engineering written by Liang Guo and published by Springer Nature. This book was released on 2020-05-04 with total page 436 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book provides a comprehensive reference to major neural interfacing technologies used to transmit signals between the physical world and the nervous system for repairing, restoring and even augmenting body functions. The authors discuss the classic approaches for neural interfacing, the major challenges encountered, and recent, emerging techniques to mitigate these challenges for better chronic performances. Readers will benefit from this book’s unprecedented scope and depth of coverage on the technology of neural interfaces, the most critical component in any type of neural prostheses. Provides comprehensive coverage of major neural interfacing technologies; Reviews and discusses both classic and latest, emerging topics; Includes classification of technologies to provide an easy grasp of research and trends in the field.
Download or read book Development of Thin Film Polymer Flexible Microelectrode Arrays for Neural Interface Applications written by Jiwan Kim and published by . This book was released on 2008 with total page 150 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Intra cortical Microelectrode Arrays for Neuro interfacing written by Salam Ramy Gabran and published by . This book was released on 2012 with total page 159 pages. Available in PDF, EPUB and Kindle. Book excerpt: Neuro-engineering is an emerging multi-disciplinary domain which investigates the electrophysiological activities of the nervous system. It provides procedures and techniques to explore, analyze and characterize the functions of the different components comprising the nervous system. Neuro-engineering is not limited to research applications; it is employed in developing unconventional therapeutic techniques for treating different neurological disorders and restoring lost sensory or motor functions. Microelectrodes are principal elements in functional electric stimulation (FES) systems used in electrophysiological procedures. They are used in establishing an interface with the individual neurons or in clusters to record activities and communications, as well as modulate neuron behaviour through stimulation. Microelectrode technologies progressed through several modifications and innovations to improve their functionality and usability. However, conventional electrode technologies are open to further development, and advancement in microelectrodes technology will progressively meliorate the neuro-interfacing and electrotherapeutic techniques. This research introduced design methodology and fabrication processes for intra-cortical microelectrodes capable of befitting a wide range of design requirements and applications. The design process was employed in developing and implementing an ensemble of intra-cortical microelectrodes customized for different neuro-interfacing applications. The proposed designs presented several innovations and novelties. The research addressed practical considerations including assembly and interconnection to external circuitry. The research was concluded by exhibiting the Waterloo Array which is a high channel count flexible 3-D neuro-interfacing array. Finally, the dissertation was concluded by demonstrating the characterization, in vitro and acute in vivo testing results of the Waterloo Array. The implemented electrodes were tested and benchmarked against commercial equivalents and the results manifested improvement in the electrode performance compared to conventional electrodes. Electrode testing and evaluation were conducted in the Krembil Neuroscience Centre Research Lab (Toronto Western Hospital), and the Neurosciences & Mental Health Research Institute (the Sick Kids hospital). The research results and outcomes are currently being employed in developing chronic intra-cortical and electrocorticography (ECoG) electrode arrays for the epilepsy research and rodents nervous system investigations. The introduced electrode technologies will be used to develop customized designs for the clinical research labs collaborating with CIRFE Lab.
Download or read book Multifunctional Flexible Polymer based Intracortical Neural Recording Microelectrodes written by David Stanley Pellinen and published by . This book was released on 2005 with total page 290 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book The Chemistry of Inorganic Biomaterials written by Christopher Spicer and published by Royal Society of Chemistry. This book was released on 2021-08-18 with total page 323 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book overviews the underlying chemistry behind the most common and cutting-edge inorganic materials in current use, or approaching use, in vivo.
Download or read book Evaluation of Local Field Potentials and Inflammatory Response to Chronic Microelectrode Rrrays in Rat Motor Cortex written by Ellen Shih and published by . This book was released on 2018 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt: Neural interface devices are being developed for applications encompassing communication interfaces between prosthetics and patients and investigative tools for understanding complex neural circuitry. This work investigates encapsulation materials and strategies for chronic recording of neural electrical signals for intracortical electrodes. These devices could be used for brain-computer interfacing in applications related to the recording of volitional intent in conditions such as brainstem stroke, spinal cord injury, and locked-in syndrome. Intracortical microelectrode arrays (MEAs), such as the Utah-style electrode array (UEA) which is currently in clinical trials for neural recording in brain-computer interfacing, suffer from a lack of chronic reliability. A number of abiotic and biotic factors have been identified as contributors to the decline in performance. The primary biotic mechanism for loss of device performance is associated with the inflammatory response that follows implantation and chronic residence in the brain parenchyma. This foreign body response is characterized by glial scarring, loss of viable neurons, and persistent astrogliosis. A significant abiotic failure mechanism involves loss of integrity of polymer encapsulation coatings that may delaminate or become ineffective as barrier coatings resulting in parasitic electrical leakage pathways and corrosion. How adverse tissue reaction and material failure in MEAs interact and affect device performance is yet to be fully understood. This thesis investigates two elements of the chronic performance of neural interfaces: 1) the use of local field potentials (LFPs) as an alternative to single-units as a quantification of recording performance of cortical interfaces, and 2) the adverse foreign body response to amorphous silicon carbide (a-SiC), as an alternative encapsulation material for intracortical devices. The performance of neural electrodes is typically quantified by the capability of the device to measure neuron single-unit activity. However, single-unit activity is challenging to use as a volitional control signal due to an observed variability of recorded action potentials at electrodes during chronic studies. It is known that LFPs represent the sum of the low frequency (
Download or read book Advances in Network Electrophysiology written by Makoto Taketani and published by Springer Science & Business Media. This book was released on 2006-11-22 with total page 488 pages. Available in PDF, EPUB and Kindle. Book excerpt: Advances in Network Electrophysiology: Using Multi Electrode Arrays explores methods for using electrophysiological techniques for monitoring the concurrent activity of ensembles of single neurons. It reviews the recent progress in both electronics and computational tools developed to analyze the functional operations of large ensembles of neurons using multi-electrode arrays and in vitro preparations. In addition, it gives readers a sense of the applications made possible by these technological tools. This volume is the reference for researchers, industry, graduate students, and postdoctoral fellows in all areas of neuroscience, cognitive neuroscience, pharmaceutical science, and bioengineering.
Download or read book Handbook of in Vivo Neural Plasticity Techniques written by and published by Academic Press. This book was released on 2018-09-01 with total page 576 pages. Available in PDF, EPUB and Kindle. Book excerpt: Handbook of in Vivo Neural Plasticity Techniques, Volume 28: A Systems Neuroscience Approach to the Neural Basis of Memory and Cognition gives a comprehensive overview of the current methods and approaches that are used to study neural plasticity from a systems neuroscience perspective. In addition, the book offers in-depth methodological advice that provides the necessary foundation for researchers establishing methods and students who need to understand the theoretical and methodological bases of these approaches. This is the ideal resource for anyone new to the study of cognitive and behavioral neuroscience who seeks an introduction to state-of-the-art techniques. Offers a comprehensive overview of state-of-the-art approaches to studying neuroplasticity in vivo Combines discussions of theoretical underpinnings with the methodological and technical aspects necessary to guarantee success Arranged in a uniform format that clearly and concisely lays out descriptions, methods and the pitfalls of various techniques
Download or read book Neuroprosthetics written by Kenneth W. Horch and published by World Scientific. This book was released on 2004 with total page 1292 pages. Available in PDF, EPUB and Kindle. Book excerpt: A study of neuroprosthetics. It is broadly divided into three sections which address: neuroanatomy and neurophysiology, biomaterials and biocompatibility, stimulation and recording techniques; clinical applications of neuroprosthetics; and future developments.
Download or read book Indwelling Neural Implants written by William M. Reichert and published by CRC Press. This book was released on 2007-12-17 with total page 300 pages. Available in PDF, EPUB and Kindle. Book excerpt: Despite enormous advances made in the development of external effector prosthetics over the last quarter century, significant questions remain, especially those concerning signal degradation that occurs with chronically implanted neuroelectrodes. Offering contributions from pioneering researchers in neuroprosthetics and tissue repair, Indwel
Download or read book Methods for Neural Ensemble Recordings written by Miguel A. L. Nicolelis and published by CRC Press. This book was released on 2007-12-03 with total page 308 pages. Available in PDF, EPUB and Kindle. Book excerpt: Extensively updated and expanded, this second edition of a bestseller distills the current state-of-the-science and provides the nuts and bolts foundation of the methods involved in this rapidly growing science. With contributions from pioneering researchers, it includes microwire array design for chronic neural recordings, new surgical techniques for chronic implantation, microelectrode microstimulation of brain tissue, multielectrode recordings in the somatosensory system and during learning, as well as recordings from the central gustatory-reward pathways. It explores the use of Brain-Machine Interface to restore neurological function and proposes conceptual and technical approaches to human neural ensemble recordings in the future.
Download or read book Neural Interface Frontiers and Applications written by Xiaoxiang Zheng and published by Springer Nature. This book was released on 2019-11-15 with total page 250 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book focuses on the frontiers of neural interface technology, including hardware, software, neural decoding and encoding, control systems, and system integration. It also discusses applications for neuroprosthetics, neural diseases and neurorobotics, and the toolkits for basic neuroscience. A neural interface establishes a direct communication channel with the central or peripheral nervous system (CNS or PNS), and enables the nervous system to interact directly with the external devices. Recent advances in neuroscience and engineering are speeding up neural interface technology, paving the way for assisting, augmenting, repairing or restoring sensorimotor and other cognitive functions impaired due to neurological disease or trauma, and so improving the quality of life of those affected. Neural interfaces are now being explored in applications as diverse as rehabilitation, accessibility, gaming, education, recreation, robotics and human enhancement. Neural interfaces also represent a powerful tool to address fundamental questions in neuroscience. Recent decades have witnessed tremendous advances in the field, with a huge impact not only in the development of neuroprosthetics, but also in our basic understanding of brain function. Neural interface technology can be seen as a bridge across the traditional engineering and basic neuroscience. This book provides researchers, graduate and upper undergraduate students from a wide range of disciplines with a cutting-edge and comprehensive summary of neural interface engineering research.
Download or read book Principles of Electrical Neural Interfacing written by Liang Guo and published by Springer Nature. This book was released on 2021-09-29 with total page 177 pages. Available in PDF, EPUB and Kindle. Book excerpt: This textbook fills a gap to supply students with the fundamental principles and tools they need to perform the quantitative analyses of the neuroelectrophysiological approaches, including both conventional and emerging ones, prevalently used in neuroscience research and neuroprosthetics. The content grows out of a course on Neuroengineering and Neuroprosthetics, which the author has taught already several times. The key problems the author addresses include (1) the universal operating mechanisms of neuroelectrophysiological approaches, (2) proper configuration of each approach, and (3) proper interpretation of the resulting signals. Efforts are made both to extract the universal principles underlying this common class of approaches and discern the unique properties of each individual approach. To address these important problems, equivalent electrical circuit modeling and signal analysis are used to unravel the functioning mechanisms and principles and provide sound interpretations to the associated signals and phenomena. This book aims to derive analytical solutions to these equivalent circuits, which can offer clear and complete mechanistic insights to the underlying biophysics.
Download or read book Bridging the Gap in Neuroelectronic Interfaces written by Jeffrey R. Capadona and published by Frontiers Media SA. This book was released on 2020-07-09 with total page 378 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Brain Computer Interfaces written by Theodore W. Berger and published by Springer Science & Business Media. This book was released on 2008-09-18 with total page 310 pages. Available in PDF, EPUB and Kindle. Book excerpt: We have come to know that our ability to survive and grow as a nation to a very large degree depends upon our scientific progress. Moreover, it is not enough simply to keep 1 abreast of the rest of the world in scientific matters. We must maintain our leadership. President Harry Truman spoke those words in 1950, in the aftermath of World War II and in the midst of the Cold War. Indeed, the scientific and engineering leadership of the United States and its allies in the twentieth century played key roles in the successful outcomes of both World War II and the Cold War, sparing the world the twin horrors of fascism and totalitarian communism, and fueling the economic prosperity that followed. Today, as the United States and its allies once again find themselves at war, President Truman’s words ring as true as they did a half-century ago. The goal set out in the Truman Administration of maintaining leadership in science has remained the policy of the U. S. Government to this day: Dr. John Marburger, the Director of the Office of Science and Technology (OSTP) in the Executive Office of the President, made remarks to that effect during his 2 confirmation hearings in October 2001. The United States needs metrics for measuring its success in meeting this goal of maintaining leadership in science and technology. That is one of the reasons that the National Science Foundation (NSF) and many other agencies of the U. S.
Download or read book Implantable Bioelectronics written by Evgeny Katz and published by John Wiley & Sons. This book was released on 2014-02-27 with total page 566 pages. Available in PDF, EPUB and Kindle. Book excerpt: Here the renowned editor Evgeny Katz has chosen contributions that cover a wide range of examples and issues in implantable bioelectronics, resulting in an excellent overview of the topic. The various implants covered include biosensoric and prosthetic devices, as well as neural and brain implants, while ethical issues, suitable materials, biocompatibility, and energy-harvesting devices are also discussed. A must-have for both newcomers and established researchers in this interdisciplinary field that connects scientists from chemistry, material science, biology, medicine, and electrical engineering.
