Download or read book International Symposium Retroviruses and Human Pathology written by Robert C. Gallo and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 551 pages. Available in PDF, EPUB and Kindle. Book excerpt: For decades retroviruses have been riding the crest of a wave of experimental research directed toward the identification of an infectious agent of human neoplastic diseases. In the early 1970s, several scientists successfully demonstrated the presence of retroviruses in numerous animal species and proved their etiological role in some related diseases. Corresponding findings in humans were somewhat discouraging. Although financial support for this line· of research declined, a few dedicated retrovirologists survived and continued to collect more biological information and technological expertise that opened a new approach to the search for a human retrovirus. The rewards came with the discovery that the genes responsible for neoplastic transformation (oncogenes) are of cellular origin and can be shuttled about by retroviruses, and with the identification of a new family of Human T-cell Lymphotrophic retroViruses (HTLV) from patients with diseases ranging from leukemia to the acquired immunodeficiency syndrome (AIDS). An understanding of the role and significance of retroviruses in human pathology requires basic knowledge of the major animal systems studied. With this perspective in mind, we present here a survey that includes general overviews, minireviews on each animal system studied with selected experimental reports and, finally, a stimulating review of the field of human retrovirology by many of the pioneer scientists who created it. We are especially grateful to Profs. C. A. Romanzi and G. C. Schito for promoting the organization of the Symposium. On behalf of the Sym posium Committee, we thank E. Soeri, L. Casarino, G. P. Gesu, M.
Download or read book International Symposium Retroviruses and Human Pathology written by Robert C. Gallo and published by Humana Press. This book was released on 2011-10-14 with total page 557 pages. Available in PDF, EPUB and Kindle. Book excerpt: For decades retroviruses have been riding the crest of a wave of experimental research directed toward the identification of an infectious agent of human neoplastic diseases. In the early 1970s, several scientists successfully demonstrated the presence of retroviruses in numerous animal species and proved their etiological role in some related diseases. Corresponding findings in humans were somewhat discouraging. Although financial support for this line· of research declined, a few dedicated retrovirologists survived and continued to collect more biological information and technological expertise that opened a new approach to the search for a human retrovirus. The rewards came with the discovery that the genes responsible for neoplastic transformation (oncogenes) are of cellular origin and can be shuttled about by retroviruses, and with the identification of a new family of Human T-cell Lymphotrophic retroViruses (HTLV) from patients with diseases ranging from leukemia to the acquired immunodeficiency syndrome (AIDS). An understanding of the role and significance of retroviruses in human pathology requires basic knowledge of the major animal systems studied. With this perspective in mind, we present here a survey that includes general overviews, minireviews on each animal system studied with selected experimental reports and, finally, a stimulating review of the field of human retrovirology by many of the pioneer scientists who created it. We are especially grateful to Profs. C. A. Romanzi and G. C. Schito for promoting the organization of the Symposium. On behalf of the Sym posium Committee, we thank E. Soeri, L. Casarino, G. P. Gesu, M.
Download or read book International Symposium on Pain written by International Symposium on Pain (1, 1973, Issaquah, Wash.) and published by . This book was released on 1600 with total page 850 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Current Catalog written by National Library of Medicine (U.S.) and published by . This book was released on 1993 with total page 1628 pages. Available in PDF, EPUB and Kindle. Book excerpt: First multi-year cumulation covers six years: 1965-70.
Download or read book Cancer Virus Hunters written by Gregory J. Morgan and published by JHU Press. This book was released on 2022-08-02 with total page 388 pages. Available in PDF, EPUB and Kindle. Book excerpt: Traces the history of the study of tumor viruses and its role in driving breakthroughs in cancer research. Worldwide, approximately one-fifth of human cancers are caused by tumor viruses, with hepatitis B virus and HPV being the leading culprits. While the explosive growth in molecular biology in the late twentieth century is well known, the role that the study of tumor viruses has played in driving many of the greatest breakthroughs is not. Without the insights gained by studying tumor viruses, many significant theoretical advancements over the last four decades in cellular and molecular biology would not have been made. More practically, the study of tumor viruses has saved thousands, if not millions, of lives. In Cancer Virus Hunters, Gregory J. Morgan traces the high points in the development of tumor virology, from Peyton Rous's pioneering work on chicken tumors in 1909 to the successful development of an HPV vaccine for cervical cancer in 2006. Morgan offers a novel approach to understanding the interconnectedness of a long series of biomedical breakthroughs, including those that led to seven Nobel prizes. Among other advances, Morgan describes and contextualizes the science that prompted the discoveries of reverse transcriptase, RNA splicing, the tumor suppressor p53, the vaccine for hepatitis B, and the HIV test. He also explores how "cancer virus hunters" have demonstrated the virtue of beginning with a simple system, even when investigating a complex disease like cancer. Based on extensive archival research and over fifty interviews with experts, Cancer Virus Hunters is a tour de force summarizing a century of research to show how discoveries made with tumor viruses came to dominate the contemporary understanding of cancer. By showcasing the scientists themselves, the book makes for an unusually accessible journey through the history of science. It will be of interest to biomedical professionals—especially in oncology, hepatology, and infectious disease—in addition to historians of science and anyone interested in cancer research.
Download or read book National Library of Medicine Current Catalog written by National Library of Medicine (U.S.) and published by . This book was released on with total page 762 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Index of Conference Proceedings Received written by British Library. Document Supply Centre and published by . This book was released on 1986 with total page 1100 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Animal Models of Human Disease written by and published by . This book was released on 1973 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Retroviruses in Human Lymphoma leukemia written by Masanao Miwa and published by VSP. This book was released on 1985-12 with total page 358 pages. Available in PDF, EPUB and Kindle. Book excerpt: In the Proceedings of this Symposium, papers are presented from leading laboratories worldwide studying human and animal retroviruses and their associated leukemias and other diseases, including AIDS. The volume provides an up-to-date review of the field and indicates possible future developments for cancer research in which multidisciplinary work, ranging from molecular biology to epidemiology, plays an important role. The book contains 31 papers which are grouped into the following subject areas: lectures; clinical aspects; epidemiology; virus transmission; characterization of viruses; infected cells; AIDS.
Download or read book Journal of the National Cancer Institute written by and published by . This book was released on 1984 with total page 600 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Chemical Abstracts Service Source Index written by American Chemical Society. Chemical Abstracts Service and published by . This book was released on 1990 with total page 1064 pages. Available in PDF, EPUB and Kindle. Book excerpt: The CAS Source Index (CASSI) Search Tool is an online resource intended to support researchers and librarians who need accurate bibliographic information. This free resource can be used to quickly and easily look up or confirm publication titles and abbreviations, as well as CODEN, ISBN, or ISSN codes. The CASSI database contains a listing of publications indexed by Chemical Abstracts Service (CAS) since 1907.
Download or read book The Writer s Directory 1998 2000 written by Miranda H. Ferrara and published by Saint James Press. This book was released on 1995 with total page 1856 pages. Available in PDF, EPUB and Kindle. Book excerpt: Information on more than 17,500 living authors from English speaking countries.
Download or read book Disease Control Priorities Third Edition Volume 6 written by King K. Holmes and published by World Bank Publications. This book was released on 2017-11-06 with total page 1027 pages. Available in PDF, EPUB and Kindle. Book excerpt: Infectious diseases are the leading cause of death globally, particularly among children and young adults. The spread of new pathogens and the threat of antimicrobial resistance pose particular challenges in combating these diseases. Major Infectious Diseases identifies feasible, cost-effective packages of interventions and strategies across delivery platforms to prevent and treat HIV/AIDS, other sexually transmitted infections, tuberculosis, malaria, adult febrile illness, viral hepatitis, and neglected tropical diseases. The volume emphasizes the need to effectively address emerging antimicrobial resistance, strengthen health systems, and increase access to care. The attainable goals are to reduce incidence, develop innovative approaches, and optimize existing tools in resource-constrained settings.
Download or read book Animal Models of Disease written by Cynthia Petrie Smith and published by . This book was released on 1992 with total page 62 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Index of Conference Proceedings Received written by British Library. Lending Division and published by . This book was released on 1988-07 with total page 456 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book JNCI Journal of the National Cancer Institute written by National Cancer Institute (U.S.) and published by . This book was released on 1984 with total page 736 pages. Available in PDF, EPUB and Kindle. Book excerpt:
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