Download or read book Interaction of 16S and 23S Ribosomal RNA with Functional Ligands Implications for the Mechanism of Protein Synthesis written by Danesh Moazed and published by . This book was released on 1989 with total page 394 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book The Role of 16 S Ribosomal RNA in Polypeptide Chain Synthesis written by Robert Alexander Baan and published by . This book was released on 1977 with total page 120 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book The Ribosome written by Aleksandr S. Spirin and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 173 pages. Available in PDF, EPUB and Kindle. Book excerpt: This monograph is neither a historical outline of the development of the concepts of protein biosynthesis and the structure and functions of the ribosomes, nor an exhaustive survey of the literature on these questions. The monograph is based upon an analysis of the modern trends in this field. The purpose of the monograph was to formulate more or less generalized representations of the structure and" function of the ribosome, as we envision it at the present day. It may be that this attempt is premature for a number of reasons, and the concepts outlined here will very soon be revised. Nonetheless, despite this risk, we believe it to be advisable to undertake this attempt for the following reasons: firstly, the undertaken analysis could aid in the comprehension of the substantial mass of extremely scattered experimental data on the ribosomes presently available; secondly, in any event, even if most of the concepts outlined rapidly become obselete, they can still serve as a stimulus for a whole series of experiments; and thirdly, we hope that some of the concepts outlined will still remain essentially correct and relatively stable. In view of the aforementioned, we should make the following reservations. First of all, we made no attempt to cite all the literature on the problems discussed, but considered it sufficient to illustrate the various premises with one or several sample references.
Download or read book Dissertation Abstracts International written by and published by . This book was released on 2001 with total page 816 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book The 16S Ribosomal RNA Decoding Domain in Translational Initiation the Interaction Between 23S Ribosomal RNA Fragment and Protein L1 written by Peining Dong and published by . This book was released on 1994 with total page 350 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book The Alkali Metal Ions Their Role for Life written by Astrid Sigel and published by Springer. This book was released on 2016-02-09 with total page 663 pages. Available in PDF, EPUB and Kindle. Book excerpt: MILS-16 provides an up-to-date review of the impact of alkali metal ions on life. Their bioinorganic chemistry and analytical determination, the solid state structures of bio-ligand complexes and the properties of alkali metal ions in solution in the context of all kinds of biologically relevant ligands are covered, this includes proteins (enzymes) and nucleic acids (G-quadruplexes). Minerals containing sodium (Na+) and potassium (K+) are abundant in the Earth's crust, making Na+ and K+ easily available. In contrast, the alkali elements lithium (Li+), rubidium, and cesium are rare and the radioactive francium occurs only in traces. Since the intra- and extracellular, as well as the compartmental concentrations of Na+ and K+ differ significantly, homeostasis and active transport of these ions are important; this involves transporters/carriers and pore-forming ion channel proteins. Systems like Na+/K+-ATPases, H+/K+-ATPases or Na+/H+ antiporters are thoroughly discussed. The role of K+ in photosynthesis and the role of Na+ in charging the "battery of life" are pointed out. Also, the relationships between alkali metal ions and diseases (e.g., Parkinson or traumatic brain injury) are covered and the relevance of Li+ salts in medicine (pharmacology and mechanism) is reviewed. This and more is treated in an authoritative and timely manner in the 16 stimulating chapters of Volume 16, The Alkali Metal Ions: Their Role for Life, which are written by 44 internationally recognized experts from 12 nations. The impact of this vibrant research area is manifested in nearly 3000 references, over 30 tables and more than 150 illustrations (two thirds in color). MILS-16 also provides excellent information for teaching. Astrid Sigel, Helmut Sigel, and Roland K. O. Sigel have long-standing interests in Biological Inorganic Chemistry. Their research focuses on metal ion interactions with nucleotides and nucleic acids and on related topics. They edited previously 44 volumes in the series Metal Ions in Biological Systems.
Download or read book The Ribosome Structure Function Evolution written by and published by . This book was released on 1990 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book The Interaction Between Ribosomal Protein S8 and Its Binding Sites on 16S RRNA and Spc MRNA the Minimum Structural Elements of 23S RRNA Required for Binding with Ribosomal Protein L1 written by Lihong Jiang and published by . This book was released on 1994 with total page 172 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Modulation of Translational Fidelity by Small Subunit Ribosoma RNA from Escherichia Coli written by Fazilah Abdul-Latif and published by . This book was released on 1988 with total page 198 pages. Available in PDF, EPUB and Kindle. Book excerpt: Ribosomes are ribonucleoprotein particles that are essential for the process of protein synthesis in all living systems. Escherichia coli, eubacterial organisms, have ribosomes which display a 70S sedimentation coefficient. They are formed by the association of two ribonucleoprotein subunits which sediment at 50S and 30S. The 30S subunit is a construct made of 21 different proteins and 16S ribosomal RNA. The 3'-terminus of this rRNA was the focus of the research recounted in this dissertation. This tract of 10 nucleotides in rRNA is absolutely conserved in eubacterial organisms and is asserted to be crucial for proper initiation of protein synthesis in eubacteria. Here I report the results of experiments done with 16S rRNA missing a part of the conserved 3'-terminus. These experiments were undertaken to provide a refinement of our understanding of the requirement for and function of this conserved segment of 16S rRNA. The deletions were made directly within mature 16S rRNA using RNase H and a 10 nucleotide synthetic DNA complementary to the 3'-terminus of 16S rRNA. The synthetic DNA was hybridized to 16S rRNA and then treated with RNase H. RNase H will only attack RNA when it is basepaired with DNA. This permits site-directed mutagenisis on the mature RNA. This deletion strategy efficiently yielded a 3'-terminal nucleotide deletion in E. coli 16S rRNA. This 3'-terminal deletion did not impair in vitro 30S subunit assembly. Therefore, the conservation of the sequence is not necessary for ribosome assembly. To investigate the functional properties of the modified particles an in vitro protein translation system primed with a natural mRNA was employed. The mRNA was viral MS2 messenger. Modified particles did translate the MS2 mRNA but the fidelity with which the translation occurred was diminished.
Download or read book Translation Initiation Reconstituted Systems and Biophysical Methods written by and published by Academic Press. This book was released on 2007-10-23 with total page 512 pages. Available in PDF, EPUB and Kindle. Book excerpt: For over fifty years the Methods in Enzymology series has been the critically aclaimed laboratory standard and one of the most respected publications in the field of biochemistry. The highly relevant material makes it an essential publication for researchers in all fields of life and related sciences. This volume, the second of three on the topic of Translation Initiation includes articles written by leaders in the field.
Download or read book Ribosomes Structure Function and Dynamics written by Marina V. Rodnina and published by Springer Science & Business Media. This book was released on 2011-12-10 with total page 428 pages. Available in PDF, EPUB and Kindle. Book excerpt: The ribosome is a macromolecular machine that synthesizes proteins with a high degree of speed and accuracy. Our present understanding of its structure, function and dynamics is the result of six decades of research. This book collects over 40 articles based on the talks presented at the 2010 Ribosome Meeting, held in Orvieto, Italy, covering all facets of the structure and function of the ribosome. New high-resolution crystal structures of functional ribosome complexes and cryo-EM structures of translating ribosomes are presented, while partial reactions of translation are examined in structural and mechanistic detail, featuring translocation as a most dynamic process. Mechanisms of initiation, both in bacterial and eukaryotic systems, translation termination, and novel details of the functions of the respective factors are described. Structure and interactions of the nascent peptide within, and emerging from, the ribosomal peptide exit tunnel are addressed in several articles. Structural and single-molecule studies reveal a picture of the ribosome exhibiting the energy landscape of a processive Brownian machine. The collection provides up-to-date reviews which will serve as a source of essential information for years to come.
Download or read book Encyclopedia of Microbiology Four Volume Set written by Martin Alexander and published by Academic Press. This book was released on 2000-02-10 with total page 963 pages. Available in PDF, EPUB and Kindle. Book excerpt: The First Edition of the Encyclopedia of Microbiology was hailed by leading scientists and researchers around the world as "excellent," "outstanding," and "impressive." This Second Edition will serve as an up-to-date version of this reference which has been useful to academic, industrial, and personal libraries for years. The Encyclopedia of Microbiology, Second Edition both challenges and stimulates the reader, and illustrates the importance of microbiology, a field that cannot be over emphasized in this booming biotechnology age. Key Features * Completely redesigned and revised approach with 65% new material * Contains approximately 300 articles, 1000 illustrations, and 400 tables * New design includes thematic table of contents, combined glossary of terms, and appendix * Provides color plate sections in each volume * 17 subject areas, including exciting coverage of microbes in extreme environments and microbes in emerging infections
Download or read book American Doctoral Dissertations written by and published by . This book was released on 1989 with total page 760 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Index Medicus written by and published by . This book was released on 2004 with total page 2036 pages. Available in PDF, EPUB and Kindle. Book excerpt: Vols. for 1963- include as pt. 2 of the Jan. issue: Medical subject headings.
Download or read book Cumulated Index Medicus written by and published by . This book was released on 1999 with total page 1860 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book The Ribosome written by and published by CSHL Press. This book was released on 2001 with total page 660 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Protein Synthesis and Ribosome Structure written by Knud H. Nierhaus and published by John Wiley & Sons. This book was released on 2004-10-15 with total page 608 pages. Available in PDF, EPUB and Kindle. Book excerpt: Knud Nierhaus, who has studied the ribosome for more than 30 years, has assembled here the combined efforts of several scientific disciplines into a uniform picture of the largest enzyme complex found in living cells, finally resolving many decades-old questions in molecular biology. In so doing he considers virtually all aspects of ribosome structure and function -- from the molecular mechanism of different ribosomal ribozyme activities to their selective inhibition by antibiotics, from assembly of the core particle to the regulation of ribosome component synthesis. The result is a premier resource for anyone with an interest in ribosomal protein synthesis, whether in the context of molecular biology, biotechnology, pharmacology or molecular medicine.
