Download or read book Insights in Statistical Genetics and Methodology 2022 written by Simon Charles Heath and published by Frontiers Media SA. This book was released on 2023-10-24 with total page 172 pages. Available in PDF, EPUB and Kindle. Book excerpt: This Research Topic is part of the Insights in Frontiers in Genetics series.

Download or read book Data Mining and Statistical Methods for Knowledge Discovery in Diseases Based on Multimodal Omics written by Jiajie Peng and published by Frontiers Media SA. This book was released on 2022-06-06 with total page 160 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Forensic Investigative Genetic Genealogy and Fine Scale Structure of Human Populations written by Guanglin He and published by Frontiers Media SA. This book was released on 2023-02-03 with total page 150 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Advances in Statistical Methods for the Genetic Dissection of Complex Traits in Plants written by Yuan-Ming Zhang and published by Frontiers Media SA. This book was released on 2024-01-26 with total page 278 pages. Available in PDF, EPUB and Kindle. Book excerpt: Genome-wide association studies (GWAS) have been widely used in the genetic dissection of complex traits. However, there are still limits in current GWAS statistics. For example, (1) almost all the existing methods do not estimate additive and dominance effects in quantitative trait nucleotide (QTN) detection; (2) the methods for detecting QTN-by-environment interaction (QEI) are not straightforward and do not estimate additive and dominance effects as well as additive-by-environment and dominance-by-environment interaction effects, leading to unreliable results; and (3) no or too simple polygenic background controls have been employed in QTN-by-QTN interaction (QQI) detection. As a result, few studies of QEI and QQI for complex traits have been reported based on multiple-environment experiments. Recently, new statistical tools, including 3VmrMLM, have been developed to address these needs in GWAS. In 3VmrMLM, all the trait-associated effects, including QTN, QEI and QQI related effects, are compressed into a single effect-related vector, while all the polygenic backgrounds are compressed into a single polygenic effect matrix. These compressed parameters can be accurately and efficiently estimated through a unified mixed model analysis. To further validate these new GWAS methods, particularly 3VmrMLM, they should be rigorously tested in real data of various plants and a wide range of other species.

Download or read book Systems Genetics of Human Complex Diseases Volume II written by Guiyou Liu and published by Frontiers Media SA. This book was released on 2022-08-19 with total page 222 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Methods for Ecological Research on Terrestrial Small Mammals written by Robert McCleery and published by JHU Press. This book was released on 2022-01-04 with total page 381 pages. Available in PDF, EPUB and Kindle. Book excerpt: All the information researchers, students, and practitioners need to conducted innovative, state-of-the-art research on small mammals. Rodents and insectivores constitute the vast majority of mammals on our planet, yet we often overlook the importance of this group. As seed dispersers, prey species, and disease regulators, these animals are critical to the functioning of our ecological systems. While considerable material exists that describes these species, there has been no dedicated guide explaining how to effectively research them—until now. Methods for Ecological Research on Terrestrial Small Mammals is a one-stop resource compiling all the information readers need to conduct state-of-the-art research on small terrestrial mammals across the globe. The authors cover the full spectrum of issues, from capture, handling, identification, reproduction, demography, and taxonomy to behavior, diet, evolution, diseases, movements, morphometrics, and more. They also: • highlight the latest techniques while carefully explaining the tried-and-tested methods needed to conduct rigorous scientific inquiries; • provide step-by-step examples and case studies, demonstrating how the methods discussed can be used in actual research projects; • compare and contrast methodologies, analytical techniques, and software packages, helping researchers determine which pathways and tools will yield the best results for their studies. A comprehensive and invaluable resource, Methods for Ecological Research on Terrestrial Small Mammals is a must-have for any ecologist working on small mammals.

Download or read book Application of Novel Statistical and Machine learning Methods to High dimensional Clinical Cancer and Multi Omics data written by Chao Xu and published by Frontiers Media SA. This book was released on 2022-02-02 with total page 136 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Statistical Approaches in Omics Data Association Studies written by Qi Yan and published by Frontiers Media SA. This book was released on 2022-06-07 with total page 169 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Genetics of familial hypercholesterolemia New insight Volume II written by Alpo Juhani Vuorio and published by Frontiers Media SA. This book was released on 2023-01-04 with total page 162 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book System Biology Methods and Tools for Integrating Omics Data Volume II written by Liang Cheng and published by Frontiers Media SA. This book was released on 2022-09-07 with total page 158 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Developmental Psychopathology written by Jim Stevenson and published by Springer Nature. This book was released on 2023-12-18 with total page 432 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book addresses the question of whether or not behavioural differences between children can be most appropriately characterised by dimensions of psychological problems or by categorical diagnoses. It describes the concepts and methods that have been developed and applied within developmental psychopathology using this dimensional approach. The book reviews evidence on the interplay between genes and the environment in influencing internalising problems, externalising problems, Attention Deficit Hyperactivity Disorder (ADHD) and Autism Spectrum Disorder (ASD), and on the hierarchical factor structure underlying these behavioural dimensions. It provides an appraisal of the state of knowledge on the longer-term sequelae of these problems and on the efficacy of treatments that have been developed for them.Key areas of coverage include: Multivariate data analytic methods for investigating behavioural differences (e.g., path analysis, cluster analysis, structural equation modelling, network analysis) and their associated theoretical frameworks (e.g., hierarchical factor models). Methods to investigate the biology of behavioural differences (e.g., quantitative and molecular genetics, epigenetics, and brain imaging). The design of research studies that can test most directly for causality (i.e., randomised controlled trials) and others that can estimate plausible causal relationships from associations and correlations. Reviews of studies that have applied these methods to understand the developmental course of internalising and externalising behaviours and the neurodevelopmental problems of Attention Deficit Hyperactivity Disorder (ADHD) and Autism Spectrum Disorder (ASD). Developmental Psychopathology is an essential reference for researchers, professors, and graduate students as well as clinicians and other professionals in developmental psychology, clinical child and school psychology, child and adolescent psychiatry, paediatrics, clinical social work, public health, educational psychology, and all related disciplines.

Download or read book Computational methods for microbiome analysis volume 2 written by Setubal and published by Frontiers Media SA. This book was released on 2023-01-04 with total page 223 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Advancement in Gene Set Analysis Gaining Insight From High throughput Data written by Farhad Maleki and published by Frontiers Media SA. This book was released on 2022-08-01 with total page 195 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Prospects and challenges for the implementation of HTS genetic methods in fisheries research surveys and stock assessments written by Fran Saborido-Rey and published by Frontiers Media SA. This book was released on 2023-08-02 with total page 214 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Handbook of Statistical Genetics written by David J. Balding and published by John Wiley & Sons. This book was released on 2008-06-10 with total page 1616 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Handbook for Statistical Genetics is widely regarded as the reference work in the field. However, the field has developed considerably over the past three years. In particular the modeling of genetic networks has advanced considerably via the evolution of microarray analysis. As a consequence the 3rd edition of the handbook contains a much expanded section on Network Modeling, including 5 new chapters covering metabolic networks, graphical modeling and inference and simulation of pedigrees and genealogies. Other chapters new to the 3rd edition include Human Population Genetics, Genome-wide Association Studies, Family-based Association Studies, Pharmacogenetics, Epigenetics, Ethic and Insurance. As with the second Edition, the Handbook includes a glossary of terms, acronyms and abbreviations, and features extensive cross-referencing between the chapters, tying the different areas together. With heavy use of up-to-date examples, real-life case studies and references to web-based resources, this continues to be must-have reference in a vital area of research. Edited by the leading international authorities in the field. David Balding - Department of Epidemiology & Public Health, Imperial College An advisor for our Probability & Statistics series, Professor Balding is also a previous Wiley author, having written Weight-of-Evidence for Forensic DNA Profiles, as well as having edited the two previous editions of HSG. With over 20 years teaching experience, he’s also had dozens of articles published in numerous international journals. Martin Bishop – Head of the Bioinformatics Division at the HGMP Resource Centre As well as the first two editions of HSG, Dr Bishop has edited a number of introductory books on the application of informatics to molecular biology and genetics. He is the Associate Editor of the journal Bioinformatics and Managing Editor of Briefings in Bioinformatics. Chris Cannings – Division of Genomic Medicine, University of Sheffield With over 40 years teaching in the area, Professor Cannings has published over 100 papers and is on the editorial board of many related journals. Co-editor of the two previous editions of HSG, he also authored a book on this topic.

Download or read book Handbook of Statistical Bioinformatics written by Henry Horng-Shing Lu and published by Springer Nature. This book was released on 2022-12-08 with total page 406 pages. Available in PDF, EPUB and Kindle. Book excerpt: Now in its second edition, this handbook collects authoritative contributions on modern methods and tools in statistical bioinformatics with a focus on the interface between computational statistics and cutting-edge developments in computational biology. The three parts of the book cover statistical methods for single-cell analysis, network analysis, and systems biology, with contributions by leading experts addressing key topics in probabilistic and statistical modeling and the analysis of massive data sets generated by modern biotechnology. This handbook will serve as a useful reference source for students, researchers and practitioners in statistics, computer science and biological and biomedical research, who are interested in the latest developments in computational statistics as applied to computational biology.

Download or read book Suicidal behavior and depression among perinatal women Research Prevention Intervention and Treatment written by Yari Gvion and published by Frontiers Media SA. This book was released on 2024-10-01 with total page 100 pages. Available in PDF, EPUB and Kindle. Book excerpt: Suicide is a multifaceted phenomenon, with numerous contributing and facilitating factors and variables. Despite motherhood serving as a potential protective factor against suicidal tendencies, a notable prevalence of suicidality persists among pregnant and postpartum women, making suicide a leading cause of death among women with postpartum depression (PDD). Furthermore, numerous women experience emotional challenges during pregnancy, which often persist into the postpartum phase, thus making them also susceptible to depression and suicidality. This Research Topic is dedicated to studies exploring various approaches to suicidal behavior, depression as well as of non-suicidal self-injury (NSSI)among pregnant and postpartum women. The purpose of this Research Topic is to elucidate comprehensive analyses of extant knowledge and empirical data about models, theories, and specific dimensions and variables that may help us increase the understanding of suicidal phenomena among perinatal women (pregnant and postpartum). The specific goal is to identify characteristics that may be used to develop prevention and intervention methods among this at-risk population.