Download or read book Innovative Biofilm Prevention Strategies written by and published by . This book was released on 2004 with total page 88 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Innovative Biofilm Prevention Strategies written by Alex M. Bargmeyer and published by International Water Assn. This book was released on 2005 with total page 108 pages. Available in PDF, EPUB and Kindle. Book excerpt: Biofilms are ubiquitous in drinking water distribution systems, regardless of the type of treatment or disinfection employed by a utility. In general these biofilms pose no direct health threat unless their growth becomes excessive or pathogens that are inadvertently introduced into a distribution system become part of the biofilm microbial community. While biofilm can cause problems associated with taste and odor or corrosion, the possible presence and persistence of opportunistic pathogens within the biofilm may be the most important concern. Current methods employed to minimize biofilm include the use of residual disinfectants, reduction of organic matter or inorganic electron donors (e.g. ammonia) in the water, use of pipe materials and coatings that reduce the amount of biofilm accumulation, frequent flushing of pipelines, and the practice of corrosion control treatment when corroded iron pipes are present. New strategies for the control of biofilm are being discovered and tested in a wide variety of settings, but generally not within the context of drinking water distribution systems. It is therefore important to investigate the most promising new biofilm control strategies to determine their applicability to the very complex drinking water distribution system environment. The goal of this research was to investigate novel biofilm control strategies and technologies that could possibly be applied to drinking water systems. The intent of the research was to serve as an exploratory look at new control options and determine if any could warrant. Specific objectives of the work included: .Perform laboratory scale investigation of three control technologies using rotating annular reactors to simulate a drinking water distribution pipeline. .Select the most promising technology and test that technology in actual field settings under a variety of water quality and disinfectant conditions.
Download or read book Bacterial Biofilms written by Sadik Dincer and published by BoD – Books on Demand. This book was released on 2020-10-07 with total page 362 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book examines biofilms in nature. Organized into four parts, this book addresses biofilms in wastewater treatment, inhibition of biofilm formation, biofilms and infection, and ecology of biofilms. It is designed for clinicians, researchers, and industry professionals in the fields of microbiology, biotechnology, ecology, and medicine as well as graduate and postgraduate students.
Download or read book Emerging Strategies in Combatting and Managing Bacterial Biofilms written by Reham Wasfi and published by Frontiers Media SA. This book was released on 2023-08-25 with total page 139 pages. Available in PDF, EPUB and Kindle. Book excerpt: Biofilm formation is a survival strategy for many microorganisms. Within biofilms, microorganisms live in multicellular communities enclosed in a protective matrix that enables them to survive harsh conditions and resist conventional treatments. The ability of biofilm-forming microorganisms to inhabit different biotic and abiotic surfaces facilitates their widespread existence in different environments including health care facilities, water systems, ships, and even living hosts. Hence, this microbial phenotype became a major concern in various sectors including public health, medicine, and industry. The challenge imparted by the detrimental effects of biofilms has sparked the interest of many researchers in tackling this problem. Biofilms are not simply a collection of microorganisms but can be considered as new materials. Current research efforts have focused on understanding the mechanisms of biofilm formation and factors affecting their structures, as well as innovative approaches for combating biofilms and achieving rapid biofilm detection. Prevention and proper management of biofilms necessitates a deep understanding of the mechanisms of their formation and the factors affecting their development. It is established that biofilm formation undergoes multiple stages from initial surface adhesion to maturation and dispersion. However, how bacteria trigger, regulate and modulate each stage is not yet well understood. Additionally, early detection of biofilms facilitates early intervention and, consequently, reduction in the economic loss and clinical burden. However, detection of cells within biofilms is particularly challenging and innovative sensing, tracking and diagnostic technologies are needed. Clinically, biofilm formation is a key aspect of antibiotic resistance. Biofilms are not merely protective barriers against antibiotics and the host immune system, but also harbour non-growing “persister” bacteria that survive antibiotics by virtue of their dormancy. It is established that both persisters and biofilms are implicated in chronic infections. However, the triggering factors of their formation are not fully understood. Viable but non culturable (VBNC) cells is another group of non-growing bacteria that can inhabit biofilms and remain dormant for extended periods. The trigger for their formation and revival as well as clinical relevance is unclear.
Download or read book Bacterial Biofilms written by Tony Romeo and published by Springer Science & Business Media. This book was released on 2008-02-26 with total page 302 pages. Available in PDF, EPUB and Kindle. Book excerpt: Throughout the biological world, bacteria thrive predominantly in surface-attached, matrix-enclosed, multicellular communities or biofilms, as opposed to isolated planktonic cells. This choice of lifestyle is not trivial, as it involves major shifts in the use of genetic information and cellular energy, and has profound consequences for bacterial physiology and survival. Growth within a biofilm can thwart immune function and antibiotic therapy and thereby complicate the treatment of infectious diseases, especially chronic and foreign device-associated infections. Modern studies of many important biofilms have advanced well beyond the descriptive stage, and have begun to provide molecular details of the structural, biochemical, and genetic processes that drive biofilm formation and its dispersion. There is much diversity in the details of biofilm development among various species, but there are also commonalities. In most species, environmental and nutritional conditions greatly influence biofilm development. Similar kinds of adhesive molecules often promote biofilm formation in diverse species. Signaling and regulatory processes that drive biofilm development are often conserved, especially among related bacteria. Knowledge of such processes holds great promise for efforts to control biofilm growth and combat biofilm-associated infections. This volume focuses on the biology of biofilms that affect human disease, although it is by no means comprehensive. It opens with chapters that provide the reader with current perspectives on biofilm development, physiology, environmental, and regulatory effects, the role of quorum sensing, and resistance/phenotypic persistence to antimicrobial agents during biofilm growth.
Download or read book Innovative Biofilm Control Strategies written by Alex Martin Bargmeyer and published by . This book was released on 2003 with total page 242 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Innovative Strategies for the Control of Biofilm Formation in Clinical Settings written by Mohsin Khurshid and published by . This book was released on 2018 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Biofilm formation in clinical settings is an increasingly important issue particularly due to the emergence of multidrug-resistant strains, as it resulted in increased mortality, which poses a considerable financial burden on healthcare systems. The bacterial biofilms are quite resistant to the routine antimicrobial-based therapies; therefore, the novel strategies are desired in addition to the conventional antibiotics for the effective control of infections caused by biofilm-forming microbes. So far, the approaches being proposed to control the biofilm formation in clinical practice settings include the use of biofilm inhibitors and the use of modified biomaterials for the development of medical devices to thwart the formation of biofilms. In this chapter, we have focused on the latest developments in the anti-biofilm strategies through the interruption of the quorum-sensing system, which is crucial for biofilm formation and have summarized the various classes of antibacterial compounds for the control of biofilm formation. This agrees with the recent approaches suggested by the National Institute of Health (NIH) that advocates the use of combinational therapies based on the conventional methods and complementary treatment to explore the potential utility and safety concerns of the natural products. The studies regarding these emerging strategies could possibly lead to the establishment of better therapeutic alternates compared to conventional treatments.
Download or read book Microbial Biofilms in Healthcare written by Karen Vickery and published by MDPI. This book was released on 2020-03-16 with total page 166 pages. Available in PDF, EPUB and Kindle. Book excerpt: Biofilms are ubiquitous and their presence in industry can lead to production losses. However, nowhere do biofilms impact human health and welfare as much as those that are found contaminating the healthcare environment, surgical instruments, equipment, and medical implantable devices. Approximately 70% of healthcare-associated infections are due to biofilm formation, resulting in increased patient morbidity and mortality. Biofilms formed on medical implants are recalcitrant to antibiotic treatment, which leaves implant removal as the principal treatment option. In this book, we investigate the role of biofilms in breast and dental implant disease and cancer. We include in vitro models for investigating treatment of chronic wounds and disinfectant action against Candida sp. Also included are papers on the most recent strategies for treating biofilm infection ranging from antibiotics incorporated into bone void fillers to antimicrobial peptides and quorum sensing.
Download or read book Microbial Biofilms written by Gianfranco Donelli and published by Humana. This book was released on 2016-08-23 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: The discovery that most of the chronic infections in humans, including the oral, lung, vaginal and foreign body-associated infections, are biofilm-based, has prompted the need to design new and properly focused preventive and therapeutic strategies for these diseases. Microbial Biofilms: Methods and Protocols provides a detailed description of the currently available methods and protocols to investigate bacterial and fungal biofilms, exhaustively illustrated and critically annotated in 25 chapters written by authors well known for their experience in the respective fields. The book has joined together microbiologists and specialists in infectious diseases, hygiene and public health involved in exploring different aspects of microbial biofilms as well as in designing new methods and/or developing innovative laboratory protocols. Written in the successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible protocols and notes on troubleshooting and avoiding known pitfalls. Authoritative and easily accessible, Microbial Biofilms: Methods and Protocols presents readers with the most established and validated experimental procedures to investigate microbial biofilms.
Download or read book Recent Trends in Biofilm Science and Technology written by Manuel Simoes and published by Academic Press. This book was released on 2020-06-04 with total page 418 pages. Available in PDF, EPUB and Kindle. Book excerpt: Recent Trends in Biofilm Science and Technology helps researchers working on fundamental aspects of biofilm formation and control conduct biofilm studies and interpret results. The book provides a remarkable amount of knowledge on the processes that regulate biofilm formation, the methods used, monitoring characterization and mathematical modeling, the problems/advantages caused by their presence in the food industry, environment and medical fields, and the current and emergent strategies for their control. Research on biofilms has progressed rapidly in the last decade due to the fact that biofilms have required the development of new analytical tools and new collaborations between biologists, engineers and mathematicians. - Presents an overview of the process of biofilm formation and its implications - Provides a clearer understanding of the role of biofilms in infections - Creates a foundation for further research on novel control strategies - Updates readers on the remarkable amount of knowledge on the processes that regulate biofilm formation
Download or read book Biofilm based Healthcare associated Infections written by Gianfranco Donelli and published by Springer. This book was released on 2014-11-10 with total page 197 pages. Available in PDF, EPUB and Kindle. Book excerpt: The aim of this book is to provide readers with a wide overview of the main healthcare-associated infections caused by bacteria and fungi able to grow as biofilm. The recently acquired knowledge on the pivotal role played by biofilm-growing microorganisms in healthcare-related infections has given a new dynamic to detection, prevention and treatment of these infections in patients admitted to both acute care hospitals and long-term care facilities. Clinicians, hygienists and microbiologists will be updated by leading scientists on the state-of-art of biofilm-based infections and on the most innovative strategies for prevention and treatment of these infections, often caused by emerging multidrug-resistant biofilm-growing microorganisms.
Download or read book Biofilm Infections written by Thomas Bjarnsholt and published by Springer. This book was released on 2014-10-11 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book will cover both the evidence for biofilms in many chronic bacterial infections as well as the problems facing these infections such as diagnostics and treatment regimes. A still increasing interest and emphasis on the sessile bacterial lifestyle biofilms has been seen since it was realized that that less than 0.1% of the total microbial biomass lives in the planktonic mode of growth. The term was coined in 1978 by Costerton et al. who defined the term biofilm for the first time.In 1993 the American Society for Microbiology (ASM) recognised that the biofilmmode of growth was relevant to microbiology. Lately many articles have been published on the clinical implications of bacterial biofilms. Both original articles and reviews concerning the biofilm problem are available.
Download or read book Biofilm based Healthcare associated Infections written by Gianfranco Donelli and published by Springer. This book was released on 2016-09-22 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: The aim of this book is to provide readers with a wide overview of the main healthcare-associated infections caused by bacteria and fungi able to grow as biofilm. The recently acquired knowledge on the pivotal role played by biofilm-growing microorganisms in healthcare-related infections has given a new dynamic to detection, prevention and treatment of these infections in patients admitted to both acute care hospitals and long-term care facilities. Clinicians, hygienists and microbiologists will be updated by leading scientists on the state-of-art of biofilm-based infections and on the most innovative strategies for prevention and treatment of these infections, often caused by emerging multidrug-resistant biofilm-growing microorganisms.
Download or read book Network proposal Innovative strategies for biofilm prevention and protein stabilization Project TP4 title Immobilization procedure for quorum quenching enzymes their characterization and evaluation for technical application written by Andreas Liese and published by . This book was released on 2013 with total page 25 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Antibiofilm Agents written by Kendra P. Rumbaugh and published by Springer Science & Business Media. This book was released on 2014-05-08 with total page 495 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book provides a survey of recent advances in the development of antibiofilm agents for clinical and environmental applications. The fact that microbes exist in structured communities called biofilms has slowly become accepted within the medical community. We now know that over 80% of all infectious diseases are biofilm-related; however, significant challenges still lie in our ability to diagnose and treat these extremely recalcitrant infections. Written by experts from around the globe, this book offers a valuable resource for medical professionals seeking to treat biofilm-related disease, academic and industry researchers interested in drug discovery and instructors who teach courses on microbial pathogenesis and medical microbiology.
Download or read book Microbial Biofilms written by Dharumadurai Dhanasekaran and published by BoD – Books on Demand. This book was released on 2016-07-13 with total page 526 pages. Available in PDF, EPUB and Kindle. Book excerpt: In the book Microbial Biofilms: Importance and applications, eminent scientists provide an up-to-date review of the present and future trends on biofilm-related research. This book is divided with four subdivisions as biofilm fundamentals, applications, health aspects, and their control. Moreover, this book also provides a comprehensive account on microbial interactions in biofilms, pyocyanin, and extracellular DNA in facilitating Pseudomonas aeruginosa biofilm formation, atomic force microscopic studies of biofilms, and biofilms in beverage industry. The book comprises a total of 21 chapters from valued contributions from world leading experts in Australia, Bulgaria, Canada, China, Serbia, Germany, Italy, Japan, the United Kingdom, the Kingdom of Saudi Arabia, Republic of Korea, Mexico, Poland, Portugal, and Turkey. This book may be used as a text or reference for everyone interested in biofilms and their applications. It is also highly recommended for environmental microbiologists, soil scientists, medical microbiologists, bioremediation experts, and microbiologists working in biocorrosion, biofouling, biodegradation, water microbiology, quorum sensing, and many other related areas. Scientists in academia, research laboratories, and industry will also find it of interest.
Download or read book The Science and Applications of Synthetic and Systems Biology written by Institute of Medicine and published by National Academies Press. This book was released on 2011-12-30 with total page 570 pages. Available in PDF, EPUB and Kindle. Book excerpt: Many potential applications of synthetic and systems biology are relevant to the challenges associated with the detection, surveillance, and responses to emerging and re-emerging infectious diseases. On March 14 and 15, 2011, the Institute of Medicine's (IOM's) Forum on Microbial Threats convened a public workshop in Washington, DC, to explore the current state of the science of synthetic biology, including its dependency on systems biology; discussed the different approaches that scientists are taking to engineer, or reengineer, biological systems; and discussed how the tools and approaches of synthetic and systems biology were being applied to mitigate the risks associated with emerging infectious diseases. The Science and Applications of Synthetic and Systems Biology is organized into sections as a topic-by-topic distillation of the presentations and discussions that took place at the workshop. Its purpose is to present information from relevant experience, to delineate a range of pivotal issues and their respective challenges, and to offer differing perspectives on the topic as discussed and described by the workshop participants. This report also includes a collection of individually authored papers and commentary.
