Download or read book Inhaled Particles VI written by J. Dodgson and published by Elsevier. This book was released on 2013-09-17 with total page 1244 pages. Available in PDF, EPUB and Kindle. Book excerpt: Inhaled Particles VI contains the proceedings of an international symposium and workshop on lung dosimetry, organized by the British Occupational Hygiene Society in cooperation with the Commission of the European Communities and held at Cambridge on September 2-6, 1985. The symposium presents results of research on the entry, destiny, and effects of respired particles, with emphasis on mechanisms and dose-response relationships. This book contains, in three separate parts, 84 papers from the symposium, 34 workshop papers, and 20 poster presentations. Parts 1 and 2 are further divided into sections. Section 1 presents several papers concerning the influence of breathing pattern and activity on regional deposition of inhaled particles. Section 2 shows comparative studies of aerosol deposition in experimental animals and humans. Subsequent sections explore the mineral content of lungs to differing exposures; biological effects of dusts; hazard parameters; dust measurement; exposure of workers to vermiculite and attapulgite; effects of dust exposure in the coal mining industry; and effects of silica dust exposure. Other topics of significance include toxicity of artificial mineral fibers and utility of magnetopneumography as a non-invasive investigational test.
Download or read book Inhaled Particles written by Chiu-sen Wang and published by Elsevier. This book was released on 2005-01-20 with total page 214 pages. Available in PDF, EPUB and Kindle. Book excerpt: Inhaled Particles integrates all that is known about inhaled particles in a unified treatment. It aims to provide a scientific framework essential to a reasonable understanding of inhaled particles. The emphasis is placed on demonstrating the key roles of lung morphology on airflow and particle transport as well as identifying physical and biological factors that influence deposition. Special attention is paid to maintaining consistency of treatment and a balance between theoretical modeling and experimental measurements. The book covers all important aspects of inhaled particles including inhalability, aerosol dispersion, particle deposition, and clearance. It reviews concisely the basic background of lung morphology, respiratory physiology, aerodynamics, and aerosol science pertinent to the subject. Essential aspects of health effects and applications are also included. An easy-to-read, self contained introduction to the field An excellent source of updated research information Useful for students and professionals in aerosol science, environmental health science, occupational hygiene, health physics and biomedical engineering
Download or read book Inhaled Particles VI written by J. Dodgson and published by . This book was released on 1988-01-01 with total page 1225 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book How Tobacco Smoke Causes Disease written by United States. Public Health Service. Office of the Surgeon General and published by . This book was released on 2010 with total page 728 pages. Available in PDF, EPUB and Kindle. Book excerpt: This report considers the biological and behavioral mechanisms that may underlie the pathogenicity of tobacco smoke. Many Surgeon General's reports have considered research findings on mechanisms in assessing the biological plausibility of associations observed in epidemiologic studies. Mechanisms of disease are important because they may provide plausibility, which is one of the guideline criteria for assessing evidence on causation. This report specifically reviews the evidence on the potential mechanisms by which smoking causes diseases and considers whether a mechanism is likely to be operative in the production of human disease by tobacco smoke. This evidence is relevant to understanding how smoking causes disease, to identifying those who may be particularly susceptible, and to assessing the potential risks of tobacco products.
Download or read book Inhaled Particles VI written by British Occupational Hygiene Society and published by . This book was released on 1988 with total page 1225 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Inhaled particles written by and published by . This book was released on 1977 with total page 26 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Hayes Principles and Methods of Toxicology Sixth Edition written by A. Wallace Hayes and published by CRC Press. This book was released on 2014-10-10 with total page 2186 pages. Available in PDF, EPUB and Kindle. Book excerpt: Hayes’ Principles and Methods of Toxicology has long been established as a reliable reference to the concepts, methodologies, and assessments integral to toxicology. The new sixth edition has been revised and updated while maintaining the same high standards that have made this volume a benchmark resource in the field. With new authors and new chapters that address the advances and developments since the fifth edition, the book presents everything toxicologists and students need to know to understand hazards and mechanisms of toxicity, enabling them to better assess risk. The book begins with the four basic principles of toxicology—dose matters, people differ, everything transforms, and timing is crucial. The contributors discuss various agents of toxicity, including foodborne, solvents, crop protection chemicals, radiation, and plant and animal toxins. They examine various methods for defining and measuring toxicity in a host of areas, including genetics, carcinogenicity, toxicity in major body systems, and the environment. This new edition contains an expanded glossary reflecting significant changes in the field. New topics in this edition include: The importance of dose–response Systems toxicology Food safety The humane use and care of animals Neurotoxicology The comprehensive coverage and clear writing style make this volume an invaluable text for students and a one-stop reference for professionals.
Download or read book Pathology of the Lungs E Book written by Bryan Corrin and published by Elsevier Health Sciences. This book was released on 2011-02-25 with total page 785 pages. Available in PDF, EPUB and Kindle. Book excerpt: With an emphasis on practical diagnostic problem solving, Pathology of the Lungs, 3rd Edition provides the pulmonary pathologist and the general surgical pathologist with an accessible, comprehensive guide to the recognition and interpretation of common and rare neoplastic and non-neoplastic lung conditions. The text is written by two authors and covers all topics in a consistent manner without the redundancies or lapses that are common in multi-authored texts. The text is lavishly illustrated with the highest quality illustrations which accurately depict the histologic, immunohistochemical and cytologic findings under consideration and it is supplemented throughout with practical tips and advice from two internationally respected experts. The user-friendly design and format allows rapid access to essential information and the incorporation throughout of relevant clinical and radiographic information makes it a complete diagnostic resource inside the reporting room. Approximately 1,000 high quality full color illustrations.Provides the user with a complete visual guide to each specimen and assists in the recognition and diagnosis of any slide looked at under the microscope. Comprehensive coverage of both common and rare lung diseases and disorders. One stop consultation resource for the reporting room or study, no need to go further to get questions answered. Clinical background and ancillary radiographs incorporated throughout.Provides the user with all of the necessary diagnostic tools to make a complete and accurate pathologic report. Practical advice and tips from two of the world’s recognized experts. Provides the trainee and general surgical pathologist with time saving diagnostic clues when dealing with difficult specimens. Consistent and uniform approach incorporated for each disease and disorder (Etiology, pathogenesis, clinical features, pathologic features, differential diagnosis) User-friendly format enables quick and easy navigation to the key information required. Extensive use of summary tables, charts and graphs throughout the text. Helps simplify and clarify complex concepts and facilitates “at a glance comparisons between entities. Extensive reference list highlights landmark articles as well as including most up-to-date citations. Directs the trainee and practitioner to the most recent and authoritative sources for further reading and investigation
Download or read book Inhalation Aerosols written by Anthony J. Hickey and published by CRC Press. This book was released on 1996-06-07 with total page 548 pages. Available in PDF, EPUB and Kindle. Book excerpt: This unique reference integrates the theory and practical use of aerosols in inhalation therapy into a single resource-presenting the physical chemistry of formulation, the physics of aerosol generation, aerodynamic behavior, and therapeutic implications. Offers up-to-date techniques for droplet and particle generation, including air-blast and ultrasonic nebulizers, propellant-driven metered-dose inhalers, dry-powder inhalers, and elecctrospray systems!
Download or read book Susceptibility to Inhaled Pollutants written by Mark J. Utell and published by ASTM International. This book was released on 1989 with total page 243 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Inhalation Toxicology written by Ulrich Mohr and published by Springer Science & Business Media. This book was released on 2013-03-07 with total page 320 pages. Available in PDF, EPUB and Kindle. Book excerpt: The International Life Sciences Institute (ILSI), a nonprofit, public foundation, was established in 1978 to advance the sciences of nutrition, toxicology, and food safety. ILSI promotes the resolution of health and safety issues in these areas by sponsoring research, conferences, publications, and educational programs. Through ILSI's programs, scientists from government, academia, and industry unite their efforts to resolve issues of critical importance to the public. As part of its commitment to understanding and resolving health and safety issues, ILSI is pleased to sponsor this series of monographs that consolidates new scientific knowledge, defines research needs, and provides a background for the effective application of scientific advances in toxicology and food safety. Alex Malaspina President International Life Sciences Institute Contents Series Foreword . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . v Contributors . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . xi Part I. Approaches to Assessing the Toxicity of Airborne Toxicants Chapter 1. Standard-Setting as an Integrative Exercise: Alchemy, Juggling, or Science? . . . . . . . . . . . . . . . . . . . . . . . 1 D. v. Bates Chapter 2. Species Differences in Inhalation Toxicology: Variations in Exposure-Dose Relationships and Macrophage Function. . . . . . . . . . . . . . . . . . . . . . . . . . . . 11 J. D. Brain Chapter 3. Cell Populations of the Respiratory System: Interspecies Diversity in Composition, Distribution, and Morphology . . . . . . . . . . . . . . . . . . . . . . . . 25 e. G. Plopper, A. Mir, J. St. George, N. Tyler, A. Mariassy, D. Wilson, S. Nishio, D. Cranz, J. Heidsiek, and D. Hyde Chapter 4. Comparative Metabolic Basis for the Disposition and Toxic Effects of Inhaled Materials . . . . . . . . . . . . . . . . . 41 A. R. Dahl Part II. Methodological Issues in Designing and Conducting Studies with Laboratory Animals Chapter 5. Exposure Facilities and Aerosol Generation and Characterization for Inhalation Experiments. . . . . . . . . .
Download or read book Aerosol Science for Industrial Hygienists written by J.H. Vincent and published by Elsevier. This book was released on 1995-10-10 with total page 431 pages. Available in PDF, EPUB and Kindle. Book excerpt: Aerosols in workplace atmospheres have been - and continue to be - a major focus of industrial hygiene. Although there are many existing texts on aerosol science and on occupational health respectively, this new book sets out to be complementary to these and to provide a link between the two fields. In particular, the central concept of worker exposure leads to a structured approach which draws together wide-ranging aspects of aerosol science within the occupational health framework. Introductory chapters are concerned with the nature and properties of aerosols, and how they are generated in the occupational environment. The book then goes on to provide a description of the fundamental mechanical properties of aerosols, in particular those mechanical properties associated with the motion of airborne particles (which govern particle transport, inhalation, deposition, sampling and control). There follows a description of the optical properties of workplace aerosols since these are important in the visual appearance of aerosols and in many aspects of measurement. The central core of the book deals with the processes which govern the nature of exposure to and the subsequent fate and effects of airborne particles, leading to a rational framework for standards, measurement and control. Finally, a chapter is added which relates what has been said about aerosols to gaseous and vapour contaminants. The book is aimed at graduate students and practitioners in industrial hygiene and other occupational (and environmental) health disciplines.
Download or read book Particle Overload In The Rat Lung And Lung Cancer written by Robert J McCunney and published by CRC Press. This book was released on 1996-06-03 with total page 314 pages. Available in PDF, EPUB and Kindle. Book excerpt: Recent inhalation toxicology studies suggest that when laboratory rats are exposed to inorganic particles to the point that lung overload occurs, both benign and malignant tumours may develop. The significance of these results for estimating human risk, however, is unclear.; Originally published as a special issue of the journal "Inhalation Toxicology", the contributions to this volume are derived from a symposium held in March, 1995, by the Environmental Medical Service of the Massachusetts Institute of Technology. Topics addressed include epidemiology, the pathology of lung tumours, maximum tolerated doses in inhalation toxicology studies, risk assessment, the extrapolation of results from animal studies to humans, current modelling techniques and regulatory concerns.
Download or read book Particle Lung Interactions written by Peter Gehr and published by CRC Press. This book was released on 2000-02-18 with total page 718 pages. Available in PDF, EPUB and Kindle. Book excerpt: This wide-ranging, comprehensive reference presents the latest developments in aerosol science and interactions between particles and the respiratory tract-utilizing an inter-disciplinary approach that integrates advances in physics, chemistry, and engineering with the epidemiological and biomedical sciences, and focusing on the dynamics of particl
Download or read book EHP written by and published by . This book was released on 1993 with total page 546 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book WHO Guidelines for Indoor Air Quality written by and published by World Health Organization. This book was released on 2010 with total page 488 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book presents WHO guidelines for the protection of public health from risks due to a number of chemicals commonly present in indoor air. The substances considered in this review, i.e. benzene, carbon monoxide, formaldehyde, naphthalene, nitrogen dioxide, polycyclic aromatic hydrocarbons (especially benzo[a]pyrene), radon, trichloroethylene and tetrachloroethylene, have indoor sources, are known in respect of their hazardousness to health and are often found indoors in concentrations of health concern. The guidelines are targeted at public health professionals involved in preventing health risks of environmental exposures, as well as specialists and authorities involved in the design and use of buildings, indoor materials and products. They provide a scientific basis for legally enforceable standards.
Download or read book Extrapolation of Dosimetric Relationships for Inhaled Particles and Gases written by James D. Crapo and published by . This book was released on 1989 with total page 400 pages. Available in PDF, EPUB and Kindle. Book excerpt: Extrapolation Modeling, Advancements and Research Issues in Lung Dosimetry; Lung Structure, Function Relationships; Species Differences in Airway Cell Distribution and Morphology; Alternative Methods to Evaluate Species Differences in Upper Airway Structure, Function; Preparation of Rat Nasal Airway Casts and Their Application to Studies of Nasal Airflow; Age Related Morphometric Analysis of Human Lung Casts; Anatomical Modeling of Microdosimetry of Inhaled Particles and Gases in the Lung; Experimental Dosimetry; Particle Deposition at the Alveolar Duct Bifurcations; Effects of Airway Branch Angle, Branch Point Number, and Gravity on Particle Deposition and Retention; Regional Deposition of Inhaled Particulates in Conducting Airways and Lung Segments; The Physical Properties of Mainstream Cigarette Smoke and Their Relationship to Deposition in the Respiratory Tract; Localization of 14C Dotriacontane Labeled Cigarette Smoke Particulate in the Dog Lung; Human Lung Clearance Following Bolus Inhalation of Radioaerosols; Effects of Ventilatory Patterns and Pre-existing Disease on Deposition of Inhaled Particles in Animals; Nasopharyngeal Uptake of Ozone in Humans and Animals; New Methods; Regional Dosimetry of Inhaled Particles Using SPECT; Dual Laser Doppler System for Real Time, Simultaneous Characterization of Aerosols by Size and Concentration; Dosimetry of Inhaled Particles by Means of Light Scattering; Modeling Approaches; Issues That Must Be Addressed When Constructing Anatomical Models of the Developing Lung; Significances of the Variability of Tracheobronchial Airway Paths and Their Air Flow Rates to Dosimetry Model Predictions of the Absorption of Gases; Predicting Respiratory Tract Clearance in Man; The Role of Particle Hygroscopicity in Aerosol Therapy and Inhalation Toxicology; Age-Dependent Lung Dosimetry of Radon Progeny; Deposition and Retention Modeling of Inhaled Cadmium in Rat and Human Lung, An Example for Extrapolation of Effects and Risk Estimation.