Download or read book Inhalation Studies Foundations Techniques written by R F. Phalen and published by . This book was released on 1994 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Inhalation Studies written by Robert F. Phalen and published by CRC Press. This book was released on 2008-10-22 with total page 288 pages. Available in PDF, EPUB and Kindle. Book excerpt: This significantly updated and expanded new edition presents the scientific foundations of inhalation research essential to the design and conduct of toxicologic studies. It incorporates the major advances that have been made in the field, including recent advances in biology and the rapidly increasing global concerns and studies on particulate air pollution. The Second Edition was motivated by: new developments in the ultrafine particle health effects and concentrated aerosol research advances in understanding postnatal lung growth and the deposition and clearance of inhaled particles new techniques in toxicity testing the explosion of knowledge in the genetic and molecular realms the introduction of a large number of transgenic animal models updated ethical guidelines for animal testing the emergence of aerosol medicine the growing threat of aerosol-related terrorism increased appreciation of nonpulmonary effects of inhaled substances use of medical scanning techniques to study respiratory tract structure the introduction of new inhalation exposure systems the emergence of aerosol concentrators for use in air pollution studies
Download or read book INHALATION STUDIES FOUNDATIONS AND TECHNIQUES written by RF. PHALEN and published by . This book was released on 1984 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Inhalation Studies written by Robert F. Phalen and published by CRC PressI Llc. This book was released on 1984 with total page 277 pages. Available in PDF, EPUB and Kindle. Book excerpt: 1. Aerosol and gases; 2. Basic morphology and physiology of the respiratory tract; 3. Establishing and controlling exposure environments; 4. Characterizing the exposure; 5. Methods for exposure animals.
Download or read book Methods in Inhalation Toxicology written by Robert F. Phalen and published by CRC Press. This book was released on 1996-11-06 with total page 174 pages. Available in PDF, EPUB and Kindle. Book excerpt: Conducting studies of natural and man-made air contaminants is a specialized research activity that draws upon skills from a variety of disciplines including toxicology, pharmacology, industrial hygiene, and environmental health. Methods in Inhalation Toxicology describes how knowledge from these disciplines is integrated into the design and conduct of inhalation studies. Each of the vital aspects of conducting these studies is discussed in detail, including the use of animal subjects and the related quality control and ethical considerations, air purification methodology, exposure atmosphere generation and characterization, inhalation exposure systems, and real-time and post-exposure biological assessments. These methods will enable you to conduct inhalation studies, easily adding any specific measures of particular interest to your research. The book covers techniques needed to: provide suitable clean air for experiments correctly generate the particles and gases being studied select the proper exposure system monitor the exposure prepare tissues for study ensure that animals do not have confounding lung disease The helpful descriptions and detailed lists of suppliers of preferred equipment and materials will help you to perform valid, reproducible inhalation toxicology studies. Methods in Inhalation Toxicology is a perfect textbook for students in toxicology programs, as well as for scientists who conduct inhalation studies in both academic and industrial environments.
Download or read book Methods in Inhalation Toxicology written by Robert F. Phalen and published by CRC Press. This book was released on 2020-04-30 with total page 171 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book focuses on an important aspect of the methods in laboratory animal inhalation toxicology. It is targeted to students in toxicology programs and scientists contemplating performing inhalation studies.
Download or read book Advances in Controlled Clinical Inhalation Studies written by D.V. Bates and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 423 pages. Available in PDF, EPUB and Kindle. Book excerpt: Advances in Controlled Clinical Inhalation Studies represents scientific work presented at the 3rd International Inhalation Symposium held 1991 in Hannover, FRG. The symposium covered the new developments in this field of research. The main pollutants of interest were acid aerosols, fog, and indoor pollutants, while with regard to biological effects, an emphasis was placed on immunotoxicological and biochemical parameters. Tests on high risk groups were also considered. Initial chapters describe the outdoor environment as well as indoor air, measurement and quality - both at home and in the workplace. Besides methods for clinical inhalation and assessing personal exposure, new methodologies are particularly presented. Further chapters focus on the relevance of clinical data for regulatory decisions.
Download or read book Methods in Inhalation Toxicology written by Robert F. Phalen and published by CRC Press. This book was released on 2020-04-30 with total page 174 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book focuses on an important aspect of the methods in laboratory animal inhalation toxicology. It is targeted to students in toxicology programs and scientists contemplating performing inhalation studies.
Download or read book The Particulate Air Pollution Controversy written by Robert F. Phalen and published by Springer Science & Business Media. This book was released on 2007-05-08 with total page 135 pages. Available in PDF, EPUB and Kindle. Book excerpt: Small invisible particles in the urban air, especially those produced by human activities, have recently stimulated intense scrutiny, debate, regulation, and legal proceedings. The stakes are high, both with respect to health impacts and economic costs, and the methods used previously to resolve similar issues are no longer adequate. Everyone on earth inhales thousands to millions of particles in each breath, so if urban particulate air pollution—particulate matter (PM)—is significantly hazardous, the negative impact on health could be staggering. Yet the activities that generate PM, such as farming, manufacturing, mining, transportation, and generating electricity, are themselves essential to human health and welfare. Scientists, regulators, legislators, activists, judges, lawyers, journalists, and representatives of the business community are actively involved in addressing the question of what should be done. This complex issue presents opportunities for critically assessing the relevant knowledge and for adopting more rigorous approaches to this and similar problems. What is the PM controversy, and why is it a good case study for how science and public policy might better interface? The PM controversy is the sum of the frequently heated debates related to the potential health risks from urban PM.
Download or read book Concepts In Inhalation Toxicology written by Roger O. McClellan and published by CRC Press. This book was released on 1995-09-25 with total page 678 pages. Available in PDF, EPUB and Kindle. Book excerpt: Recent developments have provided new data on the subject of inhalation toxicology, requiring an update of the previous edition of this popular text. Like the first, this second edition explains the basic concepts and quantitative approaches in inhalation toxicology, and it gives a comprehensive treatment of evaluations of respiratory responses to inhaled particles and gases. The author here explores new understanding of the role of cytokines in pulmonary inflammation and risk assessment. Immunologists, oncologists, respiratory specialists and students in those fields will find Concepts In Inhalation Toxicology to be essential to their practice.
Download or read book Overcoming Challenges to Develop Countermeasures Against Aerosolized Bioterrorism Agents written by National Research Council and published by National Academies Press. This book was released on 2006-08-07 with total page 87 pages. Available in PDF, EPUB and Kindle. Book excerpt: The National Institute of Allergy and Infectious Diseases (NIAID) gives the highest priority to developing countermeasures against bioterrorism agents that are highly infective when dispersed in aerosol form. Developing drugs to prevent or treat illnesses caused by bioterrorism agents requires testing their effectiveness in animals since human clinical trials would be unethical. At the request of NIAID, the National Academies conducted a study to examine how such testing could be improved. Overcoming Challenges to Develop Countermeasures Against Aerosolized Bioterrorism Agents provides recommendations to researchers on selecting the kinds of animal models, aerosol generators, and bioterrorism agent doses that would produce conditions that most closely mimic the disease process in humans. It also urges researchers to fully document experimental parameters in the literature so that studies can be reproduced and compared. The book recommends that all unclassified data on bioterrorism agent studies-including unclassified, unpublished data from U.S. Army Medical Research Institute of Infectious Diseases (USAMRIID)-be published in the open literature. The book also calls on the U.S. Food and Drug Administration to improve the process by which bioterrorism countermeasures are approved based on the results of animal studies.
Download or read book Pharmaceutical Inhalation Aerosol Technology written by Anthony J. Hickey and published by CRC Press. This book was released on 1992 with total page 400 pages. Available in PDF, EPUB and Kindle. Book excerpt: This thoroughly revised and expanded reference provides authoritative discussions on the physiologic, pharmacologic, metabolic, molecular, cellular and physicochemical factors, influencing the efficacy and utilization of pharmaceutical aerosol. It analyzes the latest science and developments in the generation, administration and characterization of these compounds, showcasing current clinical applications, the efficiency and limitations of major aerosol products and emerging aerosol therapies impacting the field.
Download or read book Handbook of Human Toxicology written by Edward J. Massaro and published by CRC Press. This book was released on 1997-07-09 with total page 1196 pages. Available in PDF, EPUB and Kindle. Book excerpt: Covering some of the most important topics in modern toxicology, the Handbook of Human Toxicology is a unique and valuable addition to the current literature. It addresses issues, answers questions, and provides data related to. Within each of these five major sections are several carefully selected topics that reflect the current state of human to
Download or read book Handbook of Toxicologic Pathology written by Wanda M Haschek and published by Elsevier. This book was released on 2013-10-22 with total page 1105 pages. Available in PDF, EPUB and Kindle. Book excerpt: This is the first comprehensive reference work on toxicologic pathology, an emerging field that integrates the mechanisms of toxic injury with the resulting pathology. Chapters deal systematically with organ-specific toxic injury, describing the mechanisms of injury, morphological expression of the injury, and evaluation of the pathology. Additional chapters introduce the field to the uninitiated and address such topics as techniques used for morphological evaluation, risk assessment, and regulatory aspects. The Handbook of Toxicologic Pathology will quickly establish itself as the classic reference work in this field for years to come. Comprehensive, "user friendly" reference text on toxicologic pathology Large, easy-to-use 8 1/2" x 11", double-column format Systematic approach to each organ or system More than 500 illustrations and 90 tables complement the text Over 2,000 references for easy access to the primary literature Unique chapters written by leading authorities
Download or read book Fundamentals of Toxicologic Pathology written by Wanda M. Haschek and published by Gulf Professional Publishing. This book was released on 1998 with total page 592 pages. Available in PDF, EPUB and Kindle. Book excerpt: Fundamentals Of Toxicologic Pathology is an enhanced and edited version of the Handbook of Toxicologic Pathology. The editors have created a more concise and affordable text for students in toxicologic pathology and scientists working in academia or industry. This volume focuses on providing basic information integrated from both toxicology and pathology dealing with the mechanisms of toxic injury and morphologic expression of that injury at subcellular, cellular, and tissue levels. The text addresses basic priniciples of toxicologic pathology and deals systematically with organ-specific injuries.
Download or read book Aerobiology written by Harry Salem and published by Royal Society of Chemistry. This book was released on 2016-04-26 with total page 518 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book focusses on the toxicological aspects of aerobiology, considering the adverse health effects associated with the inhalation of airborne biological particulates.
Download or read book Human and Ecological Risk Assessment written by Dennis J. Paustenbach and published by John Wiley & Sons. This book was released on 2024-04-15 with total page 1319 pages. Available in PDF, EPUB and Kindle. Book excerpt: Understand the fundamentals of human risk assessment with this introduction and reference Human risk assessments are a precondition for virtually all industrial action or environmental regulation, all the more essential in a world where chemical and environmental hazards are becoming more abundant. These documents catalog potential environmental, toxicological, ecological, or other harms resulting from a particular hazard, from chemical spills to construction projects to dangerous workplaces. They turn on a number of variables, of which the most significant is the degree of human exposure to the hazardous agent or process. Human and Ecological Risk Assessment combines the virtues of a textbook and reference work to introduce and analyze these vital documents. Beginning with the foundational theory of human health risk assessment, it then supplies case studies and detailed analysis illustrating the practice of producing risk assessment documents. Fully updated and authored by leading authorities in the field, the result is an indispensable work. Readers of the second edition of Human and Ecological Risk Assessment will also find: Over 40 entirely new case studies reflecting the latest in risk assessment practice Detailed discussion of hazards including air emissions, contaminated food and soil, hazardous waste sites, and many more Case studies from multiple countries to reflect diverse international standards Human and Ecological Risk Assessment is ideal for professionals and advanced graduate students in toxicology, industrial hygiene, occupational medicine, environmental science, and all related subjects.
