Download or read book In Vivo NMR Spectroscopy written by Robin A. de Graaf and published by John Wiley & Sons. This book was released on 2019-03-11 with total page 584 pages. Available in PDF, EPUB and Kindle. Book excerpt: Presents basic concepts, experimental methodology and data acquisition, and processing standards of in vivo NMR spectroscopy This book covers, in detail, the technical and biophysical aspects of in vivo NMR techniques and includes novel developments in the field such as hyperpolarized NMR, dynamic 13C NMR, automated shimming, and parallel acquisitions. Most of the techniques are described from an educational point of view, yet it still retains the practical aspects appreciated by experimental NMR spectroscopists. In addition, each chapter concludes with a number of exercises designed to review, and often extend, the presented NMR principles and techniques. The third edition of In Vivo NMR Spectroscopy: Principles and Techniques has been updated to include experimental detail on the developing area of hyperpolarization; a description of the semi-LASER sequence, which is now a method of choice; updated chemical shift data, including the addition of 31P data; a troubleshooting section on common problems related to shimming, water suppression, and quantification; recent developments in data acquisition and processing standards; and MatLab scripts on the accompanying website for helping readers calculate radiofrequency pulses. Provide an educational explanation and overview of in vivo NMR, while maintaining the practical aspects appreciated by experimental NMR spectroscopists Features more experimental methodology than the previous edition End-of-chapter exercises that help drive home the principles and techniques and offer a more in-depth exploration of quantitative MR equations Designed to be used in conjunction with a teaching course on the subject In Vivo NMR Spectroscopy: Principles and Techniques, 3rd Edition is aimed at all those involved in fundamental and/or diagnostic in vivo NMR, ranging from people working in dedicated in vivo NMR institutes, to radiologists in hospitals, researchers in high-resolution NMR and MRI, and in areas such as neurology, physiology, chemistry, and medical biology.

Download or read book Nuclear Magnetic Resonance Spectroscopy written by Joseph B. Lambert and published by John Wiley & Sons. This book was released on 2019-01-04 with total page 485 pages. Available in PDF, EPUB and Kindle. Book excerpt: Combines clear and concise discussions of key NMR concepts with succinct and illustrative examples Designed to cover a full course in Nuclear Magnetic Resonance (NMR) Spectroscopy, this text offers complete coverage of classic (one-dimensional) NMR as well as up-to-date coverage of two-dimensional NMR and other modern methods. It contains practical advice, theory, illustrated applications, and classroom-tested problems; looks at such important ideas as relaxation, NOEs, phase cycling, and processing parameters; and provides brief, yet fully comprehensible, examples. It also uniquely lists all of the general parameters for many experiments including mixing times, number of scans, relaxation times, and more. Nuclear Magnetic Resonance Spectroscopy: An Introduction to Principles, Applications, and Experimental Methods, 2nd Edition begins by introducing readers to NMR spectroscopy - an analytical technique used in modern chemistry, biochemistry, and biology that allows identification and characterization of organic, and some inorganic, compounds. It offers chapters covering: Experimental Methods; The Chemical Shift; The Coupling Constant; Further Topics in One-Dimensional NMR Spectroscopy; Two-Dimensional NMR Spectroscopy; Advanced Experimental Methods; and Structural Elucidation. Features classical analysis of chemical shifts and coupling constants for both protons and other nuclei, as well as modern multi‐pulse and multi-dimensional methods Contains experimental procedures and practical advice relative to the execution of NMR experiments Includes a chapter-long, worked-out problem that illustrates the application of nearly all current methods Offers appendices containing the theoretical basis of NMR, including the most modern approach that uses product operators and coherence-level diagrams By offering a balance between volumes aimed at NMR specialists and the structure-determination-only books that focus on synthetic organic chemists, Nuclear Magnetic Resonance Spectroscopy: An Introduction to Principles, Applications, and Experimental Methods, 2nd Edition is an excellent text for students and post-graduate students working in analytical and bio-sciences, as well as scientists who use NMR spectroscopy as a primary tool in their work.

Download or read book In Vivo Magnetic Resonance Spectroscopy II Localization and Spectral Editing written by M. Rudin and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 301 pages. Available in PDF, EPUB and Kindle. Book excerpt: Localization 1. C.S. Bosch, J.J.H. Ackerman, St. Louis, MO/USA SurfaceCoil Spectroscopy 2. P. Styles, Oxford, UK Rotating Frame Spectroscopyand Spectroscopic Imaging 3. P.A. Bottomley, Schenectady, NY/USA DepthResolved Surface Coil Spectroscopy (Dress) 4. R.J. Ordidge, J.A. Helpern, Detroit, MI/USA Image Guided Volume Selective Spectroscopy: A Comparison of Techniques for In-Vivo 31P NMR Spectroscopy of Human Brain 5. M. Decorps, D. Bourgeois, Grenoble, France Localized Spectroscopy Using Static Magnetic Field Gradients: Comparison of Techniques 6. J.A. den Hollander, P.R. Luyten, Ad J.H. Marien, Best, The Netherlands 1H NMR Spectroscopy and Spectroscopic Imaging of the Human Brain Spectral Editing and Kinetic Measurements 7. H.P. Hetherington, Birmingham, AL/USA Homo- and Heteronuclear Editing in Proton Spectroscopy 8. D. Freeman, R. Hurd, Fremont, CA/USA Metabolite Specific Methods Using Double Quantum Coherence Transfer Spectroscopy 9. B.A. Berkowitz, Research Triangle Park, NC/USA Two-Dimensional Correlated Spectroscopy In-Vivo 10. G. Navon, Tel Aviv, Israel; T. Kushnir, Tel Hashomer, Israel; N. Askenasy, O. Kaplan, Tel Aviv, Israel Two-Dimensional 31P-1H Correlation Spectroscopy in Intact Organs and Their Extracts 11. M. Rudin, A. Sauter, Basel, Switzerland Measurement of Reaction Rates In Vivo Using Magnetization Transfer Techniques.

Download or read book MRI from Picture to Proton written by Donald W. McRobbie and published by Cambridge University Press. This book was released on 2017-04-13 with total page 405 pages. Available in PDF, EPUB and Kindle. Book excerpt: MR is a powerful modality. At its most advanced, it can be used not just to image anatomy and pathology, but to investigate organ function, to probe in vivo chemistry, and even to visualise the brain thinking. However, clinicians, technologists and scientists struggle with the study of the subject. The result is sometimes an obscurity of understanding, or a dilution of scientific truth, resulting in misconceptions. This is why MRI from Picture to Proton has achieved its reputation for practical clarity. MR is introduced as a tool, with coverage starting from the images, equipment and scanning protocols and traced back towards the underlying physics theory. With new content on quantitative MRI, MR safety, multi-band excitation, Dixon imaging, MR elastography and advanced pulse sequences, and with additional supportive materials available on the book's website, this new edition is completely revised and updated to reflect the best use of modern MR technology.

Download or read book Handbook of Magnetic Resonance Spectroscopy In Vivo written by Paul A. Bottomley and published by John Wiley & Sons. This book was released on 2016-10-19 with total page 1231 pages. Available in PDF, EPUB and Kindle. Book excerpt: This handbook covers the entire field of magnetic resonance spectroscopy (MRS), a unique method that allows the non-invasive identification, quantification and spatial mapping of metabolites in living organisms–including animal models and patients. Comprised of three parts: Methodology covers basic MRS theory, methodology for acquiring, quantifying spectra, and spatially localizing spectra, and equipment essentials, as well as vital ancillary issues such as motion suppression and physiological monitoring. Applications focuses on MRS applications, both in animal models of disease and in human studies of normal physiology and disease, including cancer, neurological disease, cardiac and muscle metabolism, and obesity. Reference includes useful appendices and look up tables of relative MRS signal-to-noise ratios, typical tissue concentrations, structures of common metabolites, and useful formulae. About eMagRes Handbooks eMagRes (formerly the Encyclopedia of Magnetic Resonance) publishes a wide range of online articles on all aspects of magnetic resonance in physics, chemistry, biology and medicine. The existence of this large number of articles, written by experts in various fields, is enabling the publication of a series of eMagRes Handbooks on specific areas of NMR and MRI. The chapters of each of these handbooks will comprise a carefully chosen selection of eMagRes articles. In consultation with the eMagRes Editorial Board, the eMagRes Handbooks are coherently planned in advance by specially-selected Editors, and new articles are written to give appropriate complete coverage. The handbooks are intended to be of value and interest to research students, postdoctoral fellows and other researchers learning about the scientific area in question and undertaking relevant experiments, whether in academia or industry. Have the content of this handbook and the complete content of eMagRes at your fingertips! Visit the eMagRes Homepage

Download or read book Clinical MR Spectroscopy written by Peter B. Barker and published by Cambridge University Press. This book was released on 2010 with total page 275 pages. Available in PDF, EPUB and Kindle. Book excerpt: Covers all MR spectroscopy techniques and their clinical applications in neurological disorders, malignancies and musculoskeletal diseases.

Download or read book Methodologies for Metabolomics written by Norbert W. Lutz and published by Cambridge University Press. This book was released on 2013-01-21 with total page 641 pages. Available in PDF, EPUB and Kindle. Book excerpt: Metabolomics, the global characterisation of the small molecule complement involved in metabolism, has evolved into a powerful suite of approaches for understanding the global physiological and pathological processes occurring in biological organisms. The diversity of metabolites, the wide range of metabolic pathways and their divergent biological contexts require a range of methodological strategies and techniques. Methodologies for Metabolomics provides a comprehensive description of the newest methodological approaches in metabolomic research. The most important technologies used to identify and quantify metabolites, including nuclear magnetic resonance and mass spectrometry, are highlighted. The integration of these techniques with classical biological methods is also addressed. Furthermore, the book presents statistical and chemometric methods for evaluation of the resultant data. The broad spectrum of topics includes a vast variety of organisms, samples and diseases, ranging from in vivo metabolomics in humans and animals to in vitro analysis of tissue samples, cultured cells and biofluids.

Download or read book Magnetic Resonance Spectroscopy written by Charlotte Stagg and published by Academic Press. This book was released on 2013-11-11 with total page 376 pages. Available in PDF, EPUB and Kindle. Book excerpt: Magnetic Resonance Spectroscopy: Tools for Neuroscience Research and Emerging Clinical Applications is the first comprehensive book for non-physicists that addresses the emerging and exciting technique of magnetic resonance spectroscopy. Divided into three sections, this book provides coverage of the key areas of concern for researchers. The first, on how MRS is acquired, provides a comprehensive overview of the techniques, analysis, and pitfalls encountered in MRS; the second, on what can be seen by MRS, provides essential background physiology and biochemistry on the major metabolites studied; the final sections, on why MRS is used, constitutes a detailed guide to the major clinical and scientific uses of MRS, the current state of teh art, and recent innovations. Magnetic Resonance Spectroscopy will become the essential guide for people new to the technique and give those more familiar with MRS a new perspective. - Chapters written by world-leading experts in the field - Fully illustrated - Covers both proton and non-proton MRS - Includes the background to novel MRS imaging approaches

Download or read book In Vivo Magnetic Resonance Spectroscopy I Probeheads and Radiofrequency Pulses Spectrum Analysis written by M. Rudin and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 288 pages. Available in PDF, EPUB and Kindle. Book excerpt: RF Probeheads 1. J. Link, Faellanden, Switzerland The Design of Resonator Probes with Homogeneous Radiofrequency Fields 2. M. Schnall, Philadelphia, PA/USA Probes Tuned to Multiple Frequencies for In-Vivo NMR RF Pulses 3. P.C.M. van Zijl, Rockville, MD/USA; C.T.W. Moonen, Bethesda, MD/USA Solvent Suppression Strategies for In Vivo Magnetic Resonance Spectroscopy 4. M. Garwood, K. Ugurbil, Minneapolis, MN/USA B1 Insensitive Adiabatic RF Pulses 5. P.G. Morris, Nottingham, UK Frequency Selective Excitation Using Phase-Compensated RF Pulses in One andTwo Dimensions 6. S. Mueller, Basel, Switzerland RF Pulses for MultipleFrequency Excitation: Theory and Application Spectrum Analysis 7. R. de Beer, D. van Ormondt, Delft, The Nethelands Analysis of NMR Data Using Time Domain Fitting Procedures 8. E.B. Cady, London, UK Determination of Absolute Concentrations of Metabolites from NMR Spectra.

Download or read book In Vivo Magnetic Resonance Spectroscopy III In Vivo MR Spectroscopy Potential and Limitations written by Markus Rudin and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 199 pages. Available in PDF, EPUB and Kindle. Book excerpt: Isolated Cells and Perfused Organs 1. O. Kaplan, P.C.M. van Zijl, J.S. Cohen, Washington, DC/USA NMR Studies of Metabolism of Cells and Perfused Organs Individual Nuclei 2. S.R. Williams, London, UK In Vivo Proton Spectroscopy: Experimental Asoects and Potential 3. N. Beckmann, Basel, Switzerland In Vivo 13C Spectroscopy in Humans 4. M.J.W. Prior, R.J. Maxwell, J.R. Griffiths, London, UK Fluorine - 19F NMR Spectroscopy and Imaging In Vivo 5. J.S. Ingwall, Boston, MA/USA Measuring Cation Movements Across the Cell Wall Using NMR Spectroscopy: Sodium Movements in Striated Muscle 6. M. Rudin, A. Sauter, Basel, Switzerland In Vivo Phosphorus-31 NMR: Potential and Limitations.

Download or read book Fluorine Magnetic Resonance Imaging written by Ulrich Flogel and published by CRC Press. This book was released on 2016-10-26 with total page 426 pages. Available in PDF, EPUB and Kindle. Book excerpt: Over the past decade, fluorine (19F) magnetic resonance imaging (MRI) has garnered significant scientific interest in the biomedical research community owing to the unique properties of fluorinated materials and the 19F nucleus. Fluorine has an intrinsically sensitive nucleus for MRI. There is negligible endogenous 19F in the body and thus there is no background signal. Fluorine-containing compounds are ideal tracer labels for a wide variety of MRI applications. Moreover, the chemical shift and nuclear relaxation rate can be made responsive to physiology via creative molecular design. This book is an interdisciplinary compendium that details cutting-edge science and medical research in the emerging field of 19F MRI. Edited by Ulrich Flögel and Eric Ahrens, two prominent MRI researchers, this book will appeal to investigators involved in MRI, biomedicine, immunology, pharmacology, probe chemistry, and imaging physics.

Download or read book The Chemistry of Contrast Agents in Medical Magnetic Resonance Imaging written by Andre S. Merbach and published by John Wiley & Sons. This book was released on 2013-02-19 with total page 514 pages. Available in PDF, EPUB and Kindle. Book excerpt: Magnetic Resonance Imaging (MRI) is one of the most important tools in clinical diagnostics and biomedical research. The number of MRI scanners operating around the world is estimated to be approximately 20,000, and the development of contrast agents, currently used in about a third of the 50 million clinical MRI examinations performed every year, has largely contributed to this significant achievement. This completely revised and extended second edition: Includes new chapters on targeted, responsive, PARACEST and nanoparticle MRI contrast agents. Covers the basic chemistries, MR physics and the most important techniques used by chemists in the characterization of MRI agents from every angle from synthesis to safety considerations. Is written for all of those involved in the development and application of contrast agents in MRI. Presented in colour, it provides readers with true representation and easy interpretation of the images. A word from the Authors: Twelve years after the first edition published, we are convinced that the chemistry of MRI agents has a bright future. By assembling all important information on the design principles and functioning of magnetic resonance imaging probes, this book intends to be a useful tool for both experts and newcomers in the field. We hope that it helps inspire further work in order to create more efficient and specific imaging probes that will allow materializing the dream of seeing even deeper and better inside the living organisms. Reviews of the First Edition: "...attempts, for the first time, to review the whole spectrum of involved chemical disciplines in this technique..."—Journal of the American Chemical Society "...well balanced in its scope and attention to detail...a valuable addition to the library of MR scientists..."—NMR in Biomedicine

Download or read book Magnetic Resonance Spectroscopy in Multiple Sclerosis written by M. Filippi and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 180 pages. Available in PDF, EPUB and Kindle. Book excerpt: Recent years have witnessed dramatic advances in the development and use of magnetic resonance imaging (MRI) techniques that can provide quantitative measures with some degree of pathological specificity for the heterogeneous substrates of multiple sclerosis (MS). Magnetic resonance spectroscopy (MRS) is one of the most promising of these techniques. Thanks to MRS, axonal damage is no longer considered an end-stage phenomenon typical of only the most destructive lesions and the most unfortunate cases, but rather as a major component of the MS pathology of lesions and normal-appearing white matter at all the phases of the disease. This new concept is rapidly changing our understanding of MS pathophysiology and, as a consequence, the therapeutic strategies to modify the disease course favorably. Many of the authors have pionereed the use of MRS in MS, thus contributing to the foundation of the "axonal hypothesis".

Download or read book Foundations of Sport Related Brain Injuries written by Semyon M. Slobounov and published by Springer Science & Business Media. This book was released on 2006-08-25 with total page 482 pages. Available in PDF, EPUB and Kindle. Book excerpt: In summarizing current insights and controversies over concussions in athletics, this book makes the vital point that symptom resolution does not necessarily mean injury resolution. Research shows that dysfunctional pathways continue for extended periods even after a minor concussion. Until the consequences of short-term perturbations and long-term residual brain dysfunctions are better understood, concussions must be treated with respect and given a higher priority for continued research activity.

Download or read book Paradigms of Neural Injury written by and published by Academic Press. This book was released on 1996-05-23 with total page 355 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume includes paradigms, model systems, and techniques for the study of dysfunctions in the nervous system. The advantages and disadvantages of the approaches presented are critically discussed. - Neural injury - Developmental cell death - Disease processes and aging

Download or read book NMR written by and published by . This book was released on 1969 with total page 234 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book NMR in Medicine and Biology written by Karl H. Hausser and published by Springer. This book was released on 2012-02-24 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: 0 e From the reviews of the German edition: "NMR: readable yet professional... Through this book the reader with a scientific background becomes familiar with all important NMR phenomena, methods and conceptions... The great amount of carefully drawn figures and skillfully selected biologically relevant spectra and figures are an decisive bridge to the ... aim, to convey the NMR basics without mathematics. Besides biologists and physicians the book can be highly recommended to physicists and chemists..." #Nachrichten a. d. Chemie, Technik u. Laboratorien#1 "An extraordinary NMR textbook ... The authors succeeded in presenting the subject vividly. This book is clearly set out and easy to follow at a glance, and its numerous figures are extremely well done." #Labo#2