Download or read book Immunology of Psoriatic Disease written by Eva Reali and published by Frontiers Media SA. This book was released on 2019-07-31 with total page 193 pages. Available in PDF, EPUB and Kindle. Book excerpt: Psoriasis is a chronically relapsing inflammatory skin disorder affecting about 2% of the worldwide population. The disease is associated with important systemic manifestations, including cardiovascular comorbidities and metabolic syndrome. In addition, about 30% of patients develop joint inflammation known as psoriatic arthritis (PsA). Our knowledge on the pathogenesis of psoriasis has dramatically expanded in the last decade, suggesting the existence (or co-existence) of both auto-immune and auto-inflammatory components. Skin lesions develop from a complex interplay between keratinocytes, vascular endothelium, dendritic cells, and T cells, generating a self-sustaining inflammatory cycle. Within this cycle, epidermal CD8+ T lymphocytes specific for self-antigens may represent the major autoimmune mechanism. Despite the recent progress in the comprehension of the pathogenesis of psoriasis many questions remain open, ranging from the plaque-initiating events to the characterization of the autoimmune /autoinflammatory components of the disease. The mechanisms that link cutaneous psoriasis to its extra-cutaneous and systemic manifestations also remain vague. In this Research Topic we invited top scientists to summarize the front-line research in the field of immunology of cutaneous psoriasis and its systemic and joint manifestations. Our intention was to integrate the pillar concepts of psoriasis immunopathology with the most novel insights, aiming at providing an advanced view of this rapidly evolving and fascinating field.
Download or read book Psoriasis and Psoriatic Arthritis written by Kenneth B. Gordon and published by Springer Science & Business Media. This book was released on 2005-02-16 with total page 280 pages. Available in PDF, EPUB and Kindle. Book excerpt: First comprehensive book on this topic: Textbooks on psoriasis and psoriatic arthritis in one Newest information on Psoriasis. Written by well-known international experts. Well-structured with reader-friendly format.
Download or read book Handbook of Mouse Mutations with Skin and Hair Abnormalities written by John P. Sundberg and published by CRC Press. This book was released on 1994-05-19 with total page 582 pages. Available in PDF, EPUB and Kindle. Book excerpt: Handbook of Mouse Mutations with Skin and Hair Abnormalities presents 48 mouse mutations that are all available to the biomedical community. Many of the mouse mutations with dermatological diseases are reviewed and illustrated in detail. This popular reference book gives you a single source to use when determining which mouse mutation will best serve your needs as a biomedical tool for sophisticated research projects. The book also includes an overview of domestic animal genodermatoses to provide alternatives to mouse models that do not exist or to complement those that do. A detailed section written by renowned experts compares the biology of human and mouse skin and skin diseases in the areas of development and the use of animal models, mammalian genetics, keratin biochemistry, epidermal and hair follicle cycles and kinetics, cytokines and growth factors, keratinocyte culture systems, cutaneous carcinogenesis, cutaneous immune system, and skin changes associated with mutations of the endocrine system.
Download or read book Recent Advances In Psoriasis The Role Of The Immune System written by Barbara S Baker and published by World Scientific. This book was released on 2000-04-11 with total page 186 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book presents the evidence for the belief that psoriasis is a disease of abnormal keratinocyte proliferation induced by T cells. The latest approaches to investigating the immunopathogenesis of this disease, and a review of previous findings, are presented to give an overall picture of the current knowledge in this field. Each topic is discussed in detail, clearly illustrated and well referenced. The book should prove invaluable to clinical dermatologists, and researchers in the fields of immunology and dermatology who have an interest in skin diseases.
Download or read book Advances in Psoriasis written by Jeffrey M. Weinberg and published by Springer Nature. This book was released on 2020-11-26 with total page 423 pages. Available in PDF, EPUB and Kindle. Book excerpt: This extensively revised second edition provides an up-to-date and highly informative textbook on psoriasis. The understanding of the mechanisms behind the disease and the available treatment options have continued to develop rapidly in recent times, with this vital resource covering the latest in these management options, including targeted T-cell therapy, the use of immunomodulators, systemic therapies, and ultraviolet and laser therapy. In addition, it provides a detailed overview of the pathophysiology, comorbidities, epidemiology and triggers of the disease. Advances in Psoriasis: A Multisystemic Guide extensively details the scientific basis and practice management of psoriasis. It is therefore a vital resource for practicing and trainee dermatologists looking to develop their clinical knowledge of how to manage and treat these patients.
Download or read book Psoriasis and Psoriatic Arthritis written by Siba P. Raychaudhuri and published by CRC Press. This book was released on 2017-12-15 with total page 513 pages. Available in PDF, EPUB and Kindle. Book excerpt: Psoriasis is a life-long chronic autoimmune disease characterized by thick scaly skin lesions and often associated with severe arthritis. In psoriasis, lesions skin cells, keratinocytes, grow too quickly, resulting in thick, white, silvery or red patches on skin. Normal skin cells grow gradually and flake off about every four weeks, but psoriasis causes new skin cells to move rapidly to the surface of the skin in days rather than weeks. Psoriasis symptoms often appear on the elbows, scalp, feet, knees, hands, or lower back, or as flaking or patches on the skin. It is most common in adults, but teenagers and children can also suffer from psoriasis. Psoriasis is not only a skin condition; it is a chronic disease of the immune system. Chronic psoriasis is associated with other health conditions such as psoriatic arthritis, several inflammatory disorders, type 2 diabetes, and cardiovascular disease. This book provides extensive coverage of psoriasis and psoriatic arthritis. It features information on epidemiology and etiology of psoriasis, pathogenesis, genetics of psoriasis, clinical manifestations, and treatment options using cutting-edge drugs including adalimumab and tofacitinib. Natural phytochemicals and nutraceuticals have demonstrated efficacy in ameliorating psoriasis. The book dedicates comprehensive coverage of nutraceutical therapeutic options including antioxidants, bioactive peptides, carotenoids, alpha lipoic acid, curcumin, and whey protein. These inexpensive natural therapeutics are not associated with any known adverse side effects.
Download or read book Psoriatic and Reactive Arthritis written by Christopher T. Ritchlin and published by Elsevier Health Sciences. This book was released on 2007-01-01 with total page 258 pages. Available in PDF, EPUB and Kindle. Book excerpt: This new companion to Hochberg et al.'s Rheumatology masterwork focuses on the momentous recent advances in our understanding of the genetics and immunology of psoriatic and reactive arthritis, and their implications for diagnosis and management. Leading international authorities explore new concepts in genetic and pathogenic mechanisms and early diagnosis; provide comprehensive, well-illustrated coverage of clinical features; evaluate the very latest therapeutic options, including biologics; and discuss clinical outcome measures. Examines the very latest pathogenic mechanisms and diagnostic criteria, providing the necessary tools for early diagnosis and monitoring of disease progression. Offers comprehensive coverage of the clinical manifestations of psoriatic and reactive arthritis, including a 'mini atlas' of color plates.Examines the pros and cons of the available therapeutic options, including the very latest biological as well as traditional therapies.Includes practical discussions of clinical outcome measures, delivering ongoing tools for assessment of function, disease activity, and quality of life.
Download or read book Psoriatic and Reactive Arthritis E Book written by Christopher T. Ritchlin and published by Elsevier Health Sciences. This book was released on 2007-06-25 with total page 260 pages. Available in PDF, EPUB and Kindle. Book excerpt: This new companion to Hochberg et al.'s Rheumatology masterwork focuses on the momentous recent advances in our understanding of the genetics and immunology of psoriatic and reactive arthritis, and their implications for diagnosis and management. Leading international authorities explore new concepts in genetic and pathogenic mechanisms and early diagnosis; provide comprehensive, well-illustrated coverage of clinical features; evaluate the very latest therapeutic options, including biologics; and discuss clinical outcome measures. Examines the very latest pathogenic mechanisms and diagnostic criteria, providing the necessary tools for early diagnosis and monitoring of disease progression. Offers comprehensive coverage of the clinical manifestations of psoriatic and reactive arthritis, including a ‘mini atlas' of color plates. Examines the pros and cons of the available therapeutic options, including the very latest biological as well as traditional therapies. Includes practical discussions of clinical outcome measures, delivering ongoing tools for assessment of function, disease activity, and quality of life.
Download or read book Psoriasis written by Anca Chiriac and published by BoD – Books on Demand. This book was released on 2017-07-05 with total page 248 pages. Available in PDF, EPUB and Kindle. Book excerpt: In 2014, psoriasis was recognized as a serious noncommunicable disease in the World Health Assembly Resolution WHA67.9, with a great negative impact on patients' quality of life. Psoriasis is a worldwide chronic disease, affecting all ages and all races, and a serious global health problem. Psoriasis is a complex disease with still unknown etiology and no specific curative treatment. The chapters provide comprehensive and new description of some issues related to psoriasis research and for understanding of clinical correlations, genetic aspects, experimental research, and potential therapeutic interventions. The book could be a source of information for clinicians and researchers from different fields in raising awareness of the disease.
Download or read book Autoimmunity In Psoriasis written by Ernst H. Beutner and published by CRC Press. This book was released on 2019-06-04 with total page 285 pages. Available in PDF, EPUB and Kindle. Book excerpt: First published in 1982: The book affords a fresh outlook on the nature of psoriasis. Dermatologists and dermatopathologists have long recognized that acanthosis together with hyperkeratosis and papillomatosis are characteristic features not only of psoriasis but all of many other skin diseases.
Download or read book Treatment of Psoriasis written by Jeffrey M. Weinberg and published by Springer Science & Business Media. This book was released on 2008-09-16 with total page 187 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume provides an in-depth overview of the current state of psoriasis and its management. It reviews the clinical manifestations of psoriasis as well as psoriatic arthritis and emphasizes the evolving paradigm of therapy. Coverage includes topical and ultraviolet therapies as well as traditional systemic therapy. In addition, a major focus of the volume is on biologic therapies. New agents in development are also reviewed.
Download or read book Moderate to Severe Psoriasis Fourth Edition written by John Y. M. Koo and published by CRC Press. This book was released on 2014-03-18 with total page 422 pages. Available in PDF, EPUB and Kindle. Book excerpt: Written by experts in the dermatology field, this new fourth edition of Moderate-to-Severe Psoriasis discusses the current use of biologics and other pharmacologic and phototherapy treatments for moderate-to-severe psoriasis. Illustrated with high quality color figures, this standalone text emphasizes safe and effective treatments for the psoriasis patient that are perfect for the dermatologist in daily practice. New to this edition are chapters on day treatment programs, new agents, erythrodermic and pustular psoriasis, special populations, and pharmacogenetics.
Download or read book Psoriasis written by Alan Menter and published by CRC Press. This book was released on 2010-08-15 with total page 160 pages. Available in PDF, EPUB and Kindle. Book excerpt: This is a concise yet thorough review of the diagnosis and treatment of many forms of psoriasis and covers current concepts in the ever-expanding field of psoriasis pathophysiology. Emerging concerns, such as systemic disease associations, quality of life, and psoriatic arthritis, are discussed, plus recent advances in basic science and clinical trial data. The book is of interest to all physicians with an interest in inflammatory skin diseases with systemic associations, including dermatologists in training and practice, candidates for post-registration qualifications, primary care physicians, emergency physicians, and senior medical students.
Download or read book A Comprehensive Rheumatological and Immunological Approach to Diagnosis of Psoriatic Arthritis written by Syuichi Koarada and published by Cambridge Scholars Publishing. This book was released on 2020-07-31 with total page 456 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book provides a detailed investigation of psoriatic arthritis (PsA), a chronic rheumatic disease that involves joints, entheses and skin. Although PsA has been considered as a milder form of arthritis, in the past decade, it has been proven to be a potentially serious disease like rheumatoid arthritis (RA). Radiographic findings, clinical presentation and laboratory tests reveal that PsA is a distinct joint disorder from RA. However, early diagnosis of PsA is difficult. The book illustrates how to accurately diagnose the disease through a systematic approach to PsA. It presents typical and important case studies, alongside rarer and interesting examples. It will be of interest to rheumatologists, dermatologists, orthopedists, radiologist, physiatrists, pediatricians, general physicians, and patients and their families.
Download or read book Oxford Textbook of Psoriatic Arthritis written by Oliver FitzGerald and published by Oxford University Press. This book was released on 2018-06-28 with total page 803 pages. Available in PDF, EPUB and Kindle. Book excerpt: Psoriatic arthritis, or PsA, is now acknowledged the second most prevalent and important inflammatory arthropathy worldwide. The addition of this new textbook on PsA is a fitting and important inclusion to the Oxford Textbooks in Rheumatology series, written to reflect the significant advances in the field in recent years. With the recent advances in the understanding of pathogenesis, and the development of novel therapies, the Oxford Textbook of Psoriatic Arthritis provides a comprehensive overview of the disease. Each chapter is written by leading clinicians and scientists in the field of psoriatic arthritis, to provide a contemporary view of PsA, and a look into the future directions of research. Covering everything from epidemiology and diagnosis to genetics and pathology, detailed sections on treatment and outcomes provide an invaluable resource for the clinician. The book is also highly illustrated with both clinical images such as x-rays and histological photographs to aid clinical knowledge, and diagrams of the immunology and genetics that underlie the disease. Practical and all-inclusive, with summary boxes to distil the most important information, the Oxford Textbook of Psoriatic Arthritis will prove an invaluable resource for rheumatologists, dermatologists, trainees, and all members of the multidisciplinary team who are interested in recent advances in PsA.
Download or read book Psoriasis written by Hermenio Lima and published by BoD – Books on Demand. This book was released on 2013-04-17 with total page 194 pages. Available in PDF, EPUB and Kindle. Book excerpt: By virtue of the dynamic nature of the scientific process, the description of the type, pathogenesis and treatment of a disease is always a work in progress. The complex nature of any disease can similarly be unveiled through understanding the historical context of our current understanding, examining prevailing hypotheses, and extrapolating horizons for new research. For better development of this book, the main objective was to provide insights on the types, causes, and treatments of psoriasis. This approach might substantially improve the transference of disease knowledge for physicians and intended to improve quality of medical services that endorses training of excellence and assesses the quali?cations of physicians, most of whom will be naive to clinical dermatological practices.
Download or read book Psoriasis Advances in Knowledge and Care An Issue of Dermatologic Clinics written by Alan Menter and published by Elsevier Health Sciences. This book was released on 2014-12-27 with total page 194 pages. Available in PDF, EPUB and Kindle. Book excerpt: Psoriasis is the most prevalent autoimmune disease in the U.S. • ~125 million people worldwide have psoriasis. Commonly misunderstood and interpreted as a “cosmetic problem, psoriasis is a complex and potentially debilitating disease; nearly 60% of people with psoriasis reported their disease to be a large problem in their everyday life. This issue of Dermatologic Clinics devoted exclusively to psoriasis is edited by two leaders of the International Psoriasis Council, Dr Alan Menter and Dr Chris Griffiths. Topics include: Genetics of psoriasis; Immunopathogenesis of psoriasis; Phenotypical expressions of psoriasis; Psoriasis as a systemic disease with multiple comorbidities; Outcomes measures in the assessment of psoriasis in clinical practice and trials; Update on topical therapies for mild to moderate psoriasis; Phototherapy and photochemotherapy (PUVA) for psoriasis; Current and future oral systemic therapies for psoriasis; Current biological therapies for psoriasis; Future biological therapies for psoriasis; Psoriatic arthritis for the dermatologist; Pharmacogenomics and the future of psoriasis therapies. This information that goes to the heart of clinical practice is equally appropriate, beyond dermatologists, for internal medicine clinicians, primary care physicians, bone & joint specialists; hematologists/oncologists, and researchers in genetic targeted therapy development.
