Download or read book Cooking Well written by Jacob Taylor and published by . This book was released on 2016-06-15 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt: Cookbook tailored for those with Polycystic Kidney Disease

Download or read book Cystogenesis written by Jong Hoon Park and published by Springer. This book was released on 2016-10-12 with total page 128 pages. Available in PDF, EPUB and Kindle. Book excerpt: Autosomal Dominant Polycystic Kidney Disease (ADPKD) is a highly prevalent hereditary renal disorder in which fluid-filled cysts are appeared in both kidneys. Main causative genes of ADPKD are PKD1 and PKD2, encoding for polycystin-1 (PC1) and polycystin-2 (PC2) respectively. Those proteins are localized on primary cilia and function as mechanosensor in response to the fluid flow, translating mechanistic stimuli into calcium signaling. With mutations either of PKD1 or PKD2, hyper-activated renal tubular epithelial cell proliferation is observed, followed by disrupted calcium homeostasis and aberrant intracellular cyclic AMP (cAMP) accumulation. Increased cell proliferation with fluid secretion leads to the development of thousands of epithelial-lined, fluid-filled cysts in kidneys. It is also accompanied by interstitial inflammation, fibrosis, and finally reaching end-stage renal disease (ESRD). In human ADPKD, the age at which renal failure typically occurs is later in life, however no specific targeted medications are available to cure ADPKD. Recently, potential therapeutic targets or surrogate diagnostic biomarkers for ADPKD are proposed with the advances in the understanding of ADPKD pathogenesis, and some of them were attempted for clinical trials. Herein, we will summarize genetic and epi-genetic molecular mechanisms in ADPKD progression, and overview the currently available biomarkers or potential therapeutic reagents suggested.

Download or read book Ubik written by Philip K. Dick and published by Houghton Mifflin Harcourt. This book was released on 2012 with total page 241 pages. Available in PDF, EPUB and Kindle. Book excerpt: A mind-bending, classic Philip K. Dick novel about the perception of reality. Named as one of Time's 100 best books.

Download or read book What If Our World Is Their Heaven written by Gwen Lee and published by ABRAMS. This book was released on 2002-12-31 with total page 110 pages. Available in PDF, EPUB and Kindle. Book excerpt: Interviews with the genius behind The Man in the High Castle and countless other science fiction classics. In the field of science fiction, Philip K. Dick is unparalleled. His novel Do Androids Dream of Electric Sheep? became the classic film Blade Runner. His short story “The Minority Report” was adapted for the screen by Steven Spielberg. The Man in the High Castle has become a hit series on Amazon, and those titles represent only a small fraction of his work. In November 1982, six months before the author’s untimely death, journalist Gwen Lee recorded the first of several in-depth discussions with Philip K. Dick that continued over the course of the next three months. This transcription is a fascinating read for anyone interested in the field of science fiction. “These transcripts bring fresh insights—notably, into the imaginative biotech plot line of the unwritten The Owl in Daylight . . . Dick also discusses music, writing, philosophers and his 1974–1975 mystical visions, when the revelation of his son’s undiagnosed birth defect—‘down to anatomical details’—saved the child’s life . . . Fans will rejoice.” —Publishers Weekly

Download or read book In Pursuit of a Better Quality Life written by Risa Simon and published by Createspace Independent Publishing Platform. This book was released on 2017 with total page 90 pages. Available in PDF, EPUB and Kindle. Book excerpt: You're in need of a living kidney donor, but you're not sure how to go about the process. You've been told to share your story with family and friends-but striking up a conversation about your need for a kidney transplant (and search for a living kidney donor) is the most nerve-racking conversation you can imagine. Whether you're trying to avoid dialysis or be "free of the machine," this book can help get you there. In Pursuit of a Better Life provides communication principles, campaign strategies, template letters and old fashion relationship skills that can instantly create a desire to help. In this book, the author shares strategies taught in her motivational seminars and webinars, and with her mentoring and coaching clients. Living her best life possible as a preemptive (live-donor) kidney transplant recipient, the author invites her readers to proactively engage as their own best advocate and "join her at the top," where dreams do come true. Known as the quintessential marketing plan for finding living kidney donors, this book reveals strategies rarely discussed in your doctor's office or transplant center. Uncover this wildly successful path for attracting potential kidney donors today! ABOUT THE AUTHOR The highlight of Risa Simon's life was the day an unexpected, unrelated, living kidney donor offered to give her a kidney and tests revealed a sister-like match. That day didn't come easy-and it might never have if she wasn't willing to become a proactive contender, competing for her best life possible. Risa knows all too well what it's like to be a kidney patient trapped in a hopeless sinkhole headed towards dialysis. As she watched her renal function numbers decline, her emotions escalated. The thought of surrendering her sense of control over her future consumed her thoughts and immobilized her dreams. Unwittingly, she discovered a new paradigm after attending a kidney patient conference. The presentation she attended caused an awakening that compelled her to stand before her disease and use her voice to proactively secure her best choice - a transplant before dialysis. Today, Risa is living her best life ever as a preemptive (live-donor) transplant recipient. Her passion for helping others reflects in the names of her principal firms, The Proactive Path and the TransplantFirst Academy, a non-profit (501c3) organization leading the way to better outcomes. As an enthusiastic "positive-disruptor," she's dedicated her life to inspiring eligible kidney patients to bypass dialysis (or become dialysis-free) by proactively seeking live-donor transplant opportunities. Known for her trailblazing patient empowerment strategies, she invites her fans and followers to "join her at the top" - where dreams can come true.

Download or read book The Family Tree Guide to DNA Testing and Genetic Genealogy written by Blaine T. Bettinger and published by Penguin. This book was released on 2019-08-13 with total page 274 pages. Available in PDF, EPUB and Kindle. Book excerpt: Unlock the family secrets in your DNA! Discover the answers to your family history mysteries using the most cutting edge tool available. This plain-English guide (newly updated and expanded to include th latest DNA developments) will teach you what DNA tests are available; the pros and cons of the major testing companies; and how to choose the right test to answer your specific genealogy questions. And once you've taken a DNA test, this guide will help you use your often-overwhelming results, with tips for understanding ethnicity estimates, navigating suggested cousin matches, and using third-party tools like GEDmatch to further analyze your data. The book features: · Colorful diagrams and expert definitions that explain key DNA terms and concepts such as haplogroups and DNA inheritance patterns · Detailed guides to each of the major kinds of DNA tests and tips for selecting the DNA test that can best help you solve your family mysteries, with case studies showing how each can be useful · Information about third-party tools you can use to more thoroughly analyze your test results once you've received them · Test comparison guides and research forms to help you select the most appropriate DNA test and organize your results · Insights into how adoptees and others who know little about their ancestry can benefit from DNA testing Whether you've just heard of DNA testing or you've tested at all three major companies, this guide will give you the tools you need to unpuzzle your DNA and discover what it can tell you about your family tree.

Download or read book The Search for Philip K Dick written by Anne R Dick and published by Tachyon Publications. This book was released on 2010-11-01 with total page 289 pages. Available in PDF, EPUB and Kindle. Book excerpt: Offering an intimate perspective on the life of an important, prolific author, this revealing biography uncovers the inner workings of a cult figure through his tumultuous relationship with his third wife. Brilliant and charismatic, Philip K. Dick was known as a loyal friend, father, and husband, as well as a talented science fiction writer. His six-year marriage to the woman he described as “the love of his life” and his intellectual equal was full of passion—the meeting of soul mates. But behind the façade of an untroubled life was a man struggling with his demons, unable to trust anyone, and reliant upon his charm to navigate his increasingly dark reality and descent into drugs and madness. Exposing personal details of their married life as well as the ways he continued to haunt her even after their relationship collapsed, Anne Dick provides thorough research combined with personal memories of this mysterious man.

Download or read book Kidney Disease written by Walter A. Hunt and published by Johns Hopkins University Press. This book was released on 2011-06-01 with total page 208 pages. Available in PDF, EPUB and Kindle. Book excerpt: By understanding kidney failure—what causes it, how it may affect their lives, and what treatment options they have—people with the disease can improve their quality of life and achieve the best possible outcome.

Download or read book Primary Cilia written by and published by Academic Press. This book was released on 2009-11-30 with total page 423 pages. Available in PDF, EPUB and Kindle. Book excerpt: In recent years, the role of cilia in the study of health, development and disease has been increasingly clear, and new discoveries have made this an exciting and important field of research. This comprehensive volume, a complement to the new three-volume treatment of cilia and flagella by King and Pazour, presents easy-to-follow protocols and detailed background information for researchers working with cilia and flagella. - Covers protocols for primary cilia across several systems and species - Both classic and state-of-the-art methods readily adaptable across model systems, and designed to last the test of time - Relevant to clinicians and scientists working in a wide range of fields

Download or read book Pattern Recognition written by William Gibson and published by Penguin UK. This book was released on 2004-06-24 with total page 419 pages. Available in PDF, EPUB and Kindle. Book excerpt: 'Part-detective story, part-cultural snapshot . . . all bound by Gibson's pin-sharp prose' Arena -------------- THE FIRST NOVEL IN THE BLUE ANT TRILIOGY - READ ZERO HISTORY AND SPOOK COUNTRY FOR MORE Cayce Pollard has a new job. She's been offered a special project: track down the makers of an addictive online film that's lighting up the internet. Hunting the source will take her to Tokyo and Moscow and put her in the sights of Japanese hackers and Russian Mafia. She's up against those who want to control the film, to own it - who figure breaking the law is just another business strategy. The kind of people who relish turning the hunter into the hunted . . . A gripping spy thriller by William Gibson, bestselling author of Neuromancer. Part prophesy, part satire, Pattern Recognition skewers the absurdity of modern life with the lightest and most engaging of touches. Readers of Neal Stephenson, Ray Bradbury and Iain M. Banks won't be able to put this book down. -------------- 'Fast, witty and cleverly politicized' Guardian 'A big novel, full of bold ideas . . . races along like an expert thriller' GQ 'Dangerously hip. Its dialogue and characterization will amaze you. A wonderfully detailed, reckless journey of espionage and lies' USA Today 'A compelling, humane story with a sympathetic heroine searching for meaning and consolation in a post-everything world' Daily Telegraph 'Electric, profound. Gibson's descriptions of Tokyo, Russia and London are surreally spot-on' Financial Times

Download or read book Clinical Management of Male Infertility written by Giorgio Cavallini and published by Springer. This book was released on 2014-10-20 with total page 180 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book provides andrologists and other practitioners with reliable, up-to-date information on all aspects of male infertility and is designed to assist in the clinical management of patients. Clear guidance is offered on classification of infertility, sperm analysis interpretation and diagnosis. The full range of types and causes of male infertility are then discussed in depth. Particular attention is devoted to poorly understood conditions such as unexplained couple infertility and idiopathic male infertility, but the roles of diverse disorders, health and lifestyle factors and environmental pollution are also fully explored. Research considered stimulating for the reader is highlighted, reflecting the fascinating and controversial nature of the field. International treatment guidelines are presented and the role of diet and dietary supplements is discussed in view of their increasing importance. Clinicians will find that the book’s straightforward approach ensures that it can be easily and rapidly consulted.

Download or read book Every Tool s a Hammer written by Adam Savage and published by Atria Books. This book was released on 2020-10-27 with total page 320 pages. Available in PDF, EPUB and Kindle. Book excerpt: In this New York Times bestselling “imperative how-to for creativity” (Nick Offerman), Adam Savage—star of Discovery Channel’s Mythbusters—shares his golden rules of creativity, from finding inspiration to following through and successfully making your idea a reality. Every Tool’s a Hammer is a chronicle of my life as a maker. It’s an exploration of making, but it’s also a permission slip of sorts from me to you. Permission to grab hold of the things you’re interested in, that fascinate you, and to dive deeper into them to see where they lead you. Through stories from forty-plus years of making and molding, building and break­ing, along with the lessons I learned along the way, this book is meant to be a toolbox of problem solving, complete with a shop’s worth of notes on the tools, techniques, and materials that I use most often. Things like: In Every Tool There Is a Hammer—don’t wait until everything is perfect to begin a project, and if you don’t have the exact right tool for a task, just use whatever’s handy; Increase Your Loose Tolerance—making is messy and filled with screwups, but that’s okay, as creativity is a path with twists and turns and not a straight line to be found; Use More Cooling Fluid—it prolongs the life of blades and bits, and it prevents tool failure, but beyond that it’s a reminder to slow down and reduce the fric­tion in your work and relationships; Screw Before You Glue—mechanical fasteners allow you to change and modify a project while glue is forever but sometimes you just need the right glue, so I dig into which ones will do the job with the least harm and best effects. This toolbox also includes lessons from many other incredible makers and creators, including: Jamie Hyneman, Nick Offerman, Pixar director Andrew Stanton, Oscar-winner Guillermo del Toro, artist Tom Sachs, and chef Traci Des Jardins. And if everything goes well, we will hopefully save you a few mistakes (and maybe fingers) as well as help you turn your curiosities into creations. I hope this book serves as “creative rocket fuel” (Ed Helms) to build, make, invent, explore, and—most of all—enjoy the thrills of being a creator.

Download or read book Medical Surgical Nursing Single Volume Text and Elsevier Adaptive Learning Package written by Sharon L. Lewis and published by Elsevier. This book was released on 2014-06-17 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Corresponding chapter-by-chapter to Medical-Surgical Nursing, 9e, Elsevier Adaptive Learning combines the power of brain science with sophisticated, patented Cerego algorithms to help you learn faster and remember longer. It's fun; it's engaging; and it's constantly tracking your performance and adapting to deliver content precisely when it's needed to ensure core information is transformed into lasting knowledge. Please refer to the individual product pages for the duration of access to these products. An individual study schedule reduces cognitive workload and helps you become a more effective learner by automatically guiding the learning and review process. The mobile app offers a seamless learning experience between your smartphone and the web with your memory profile maintained and managed in the cloud. UNIQUE! Your memory strength is profiled at the course, chapter, and item level to identify personal learning and forgetting patterns. UNIQUE! Material is re-presented just before you would naturally forget it to counteract memory decay. A personalized learning pathway is established based on your learning profile, memory map, and time required to demonstrate information mastery. The comprehensive student dashboard allows you to view your personal learning progress.

Download or read book Maternal and Newborn Success written by Margot De Sevo and published by F.A. Davis. This book was released on 2016-10-19 with total page 529 pages. Available in PDF, EPUB and Kindle. Book excerpt: Assure your mastery of maternal and newborn nursing knowledge while honing your critical-thinking and test-taking skills. An easy-to-follow format parallels the content of your course, topic by topic, resulting in maternal and newborn content made manageable. The 3rd Edition of this popular resource features multiple-choice and alternate-format questions that reflect the latest advances in maternal-newborn nursing and the latest NCLEX-RN® test plan. Rationales for both correct and incorrect answers as well as test-taking tips help you critically analyze the question types. You’ll also find a wealth of alternate-format questions, including fill in the blank and select all that apply (SATA).

Download or read book The Meat Racket written by Christopher Leonard and published by Simon and Schuster. This book was released on 2014-02-18 with total page 384 pages. Available in PDF, EPUB and Kindle. Book excerpt: A former agribusiness reporter critically assesses the corporate meat industry as demonstrated by the practices of Tyson Foods, documenting the meat supply's takeover by a few powerful companies who are raising prices and outmaneuvering reforms.

Download or read book Waste Tide written by Chen Qiufan and published by Tor Books. This book was released on 2019-04-30 with total page 352 pages. Available in PDF, EPUB and Kindle. Book excerpt: A LOCUS AWARD FINALIST FOR BEST FIRST NOVEL Award-winning author Chen Qiufan's Waste Tide is a thought-provoking vision of the future. Translated by Ken Liu, who brought Cixin Liu's Hugo Award-winning The Three Body Problem to English-speaking readers. Mimi is drowning in the world's trash. She’s a waste worker on Silicon Isle, where electronics -- from cell phones and laptops to bots and bionic limbs — are sent to be recycled. These amass in towering heaps, polluting every spare inch of land. On this island off the coast of China, the fruits of capitalism and consumer culture come to a toxic end. Mimi and thousands of migrant waste workers like her are lured to Silicon Isle with the promise of steady work and a better life. They're the lifeblood of the island’s economy, but are at the mercy of those in power. A storm is brewing, between ruthless local gangs, warring for control. Ecoterrorists, set on toppling the status quo. American investors, hungry for profit. And a Chinese-American interpreter, searching for his roots. As these forces collide, a war erupts -- between the rich and the poor; between tradition and modern ambition; between humanity’s past and its future. Mimi, and others like her, must decide if they will remain pawns in this war or change the rules of the game altogether. "An accomplished eco-techno-thriller with heart and soul as well as brain. Chen Qiufan is an astute observer, both of the present world and of the future that the next generation is in danger of inheriting." – David Mitchell, New York Times bestselling author of Cloud Atlas

Download or read book Robopocalypse written by Daniel H. Wilson and published by Vintage. This book was released on 2012-04-17 with total page 418 pages. Available in PDF, EPUB and Kindle. Book excerpt: In this terrifying tale of humanity’s desperate stand against a robot uprising, Daniel H. Wilson has written the most entertaining sci-fi thriller in years. Not far into our future, the dazzling technology that runs our world turns against us. Controlled by a childlike—yet massively powerful—artificial intelligence known as Archos, the global network of machines on which our world has grown dependent suddenly becomes an implacable, deadly foe. At Zero Hour—the moment the robots attack—the human race is almost annihilated, but as its scattered remnants regroup, humanity for the first time unites in a determined effort to fight back. This is the oral history of that conflict, told by an international cast of survivors who experienced this long and bloody confrontation with the machines. Brilliantly conceived and amazingly detailed, Robopocalypse is an action-packed epic with chilling implications about the real technology that surrounds us.