Download or read book Cushing s Disease written by Edward R. Laws Jr and published by Academic Press. This book was released on 2016-11-08 with total page 240 pages. Available in PDF, EPUB and Kindle. Book excerpt: Cushing’s Disease: An Often Misdiagnosed and Not So Rare Disorder reviews the epidemiology of Cushing’s, including statistics on the incidence and prevalence of this disease. There are discussions of the signs and symptoms and the most common co-morbidities, such as diabetes mellitus, hypertension, osteoporosis, amenorrhea, and infertility. Surgical, medical, and radiotherapeutic treatments, including indications, results, risks, and complications, are reviewed. Also featured is a chapter on the patient’s perspective, coping with Cushing’s, quality of life, and psychosomatic issues. This book is essential reading for the wide range of physicians who treat patients with Cushing’s disease symptoms, as well as biomedical researchers who investigate the etiology and mechanisms of rare genetic diseases, in particular rare endocrine disorders. Reviews the basics of Cushing’s disease and its interrelation with hormones, the brain, and bodily functions Includes chapters on diagnosis, surgical, medical, and radiotherapeutic treatments, and variations in presentation, including cyclical disease Presents the cognitive and emotional aspects of Cushing’s and the long-term sequelae Offers an important resource for physicians who are accustomed to treating individual symptoms rather than a disease complex Reviews multidisciplinary management, and post-treatment management of Cushing’s, including recommendations for Cushing’s Centers of Excellence
Download or read book Hypercortisolism Understanding Cushing s Syndrome written by Patrick Kimuyu and published by GRIN Verlag. This book was released on 2018-02-06 with total page 7 pages. Available in PDF, EPUB and Kindle. Book excerpt: Document from the year 2018 in the subject Medicine - Pathology, grade: 1, Egerton University, language: English, abstract: Hormones play integral biological roles in the body, primarily the regulation of body functions. Scientific research indicates that hormones regulate a range of body functions such as reproduction, metabolism, electrolyte balance, as well as, growth and development. As such, the endocrine system is considered supreme in the regulation of biological processes of the body. Biologically, the endocrine system maintains effective communication among various body organs. This communication ensures homeostasis processes are maintained at constant levels, as well as, enabling the body to respond to changes in the external environment. From anatomical perspective, the endocrine system comprises of glands that are located at different regions of the body, which release hormones. The main components of the endocrine system are the hypothalamus, pituitary gland, thyroid gland, parathyroid gland, adrenal glands, pancreas, and the gonads. These glands release hormones through various regulatory hormonal cascades including the hypothalamic-pituitary-gonadal (HPG) axis, the hypothalamic-pituitary-adrenal (HPA) axis and the hypothalamic-pituitary-thyroidal (HPT) axis. As such, any disturbances in the regulatory hormonal cascades results into devastating medical conditions. For instance, disturbances in the HPA axis, primarily excessive release of adrenocorticotropic hormone (ACTH) results into Cushing’s syndrome. Cushing’s syndrome, also known as hypercortisolism is a disorder of the endocrine system that is characterized by excess release of cortisol. Cortisol plays various regulatory functions in all organs and tissues in the body; thus, Cushing’s syndrome affects the entire body. Epidemiological data shows that Cushing’s syndrome affects 10-15 per million people, annually. Therefore, this research paper will provide a comprehensive overview of Cushing’s syndrome. It will discuss the underlying pathology, symptoms, pathophysiology, diagnosis, and treatment of the disorder.
Download or read book Cushing s Syndrome written by Marcello D. Bronstein and published by Springer Science & Business Media. This book was released on 2010-10-01 with total page 304 pages. Available in PDF, EPUB and Kindle. Book excerpt: Cushing ́s syndrome is a relatively rare clinical disorder that is associated with many co-morbidities such as systemic hypertension, diabetes, osteoporosis, impaired immune function and growth impairment in children, all of which severely reduce quality of life and life expectancy. Cushing’s Syndrome: Pathophysiology, Diagnosis and Treatment reviews the difficulties in distinguishing Cushing’s syndrome from these and other common conditions, such as central obesity, menstrual irregularity and depression. It also provides state-of-the-art information on various strategies to establish the diagnosis of Cushing’s syndrome and the differential diagnosis among its diverse etiologies, as well as therapeutic approaches. Additionally, a range of conditions that represent challenges for the diagnosis and treatment--such as renal failure, pediatric age, cyclic hypercortisolism, and pregnancy--are covered in detail. A valuable resource not only for endocrinologists but also internal medicine physicians, gynecologists, pediatricians, , pituitary surgeons and urologists, Cushing’s Syndrome: Pathophysiology, Diagnosis and Treatment provides insights by experts that will help all physicians dealing with Cushing ́s syndrome to expand their knowledge about the condition and provide targeted, comprehensive care.
Download or read book Androgens in Gynecological Practice written by Leo Plouffe, Jr and published by Cambridge University Press. This book was released on 2015-06-25 with total page 261 pages. Available in PDF, EPUB and Kindle. Book excerpt: A practical approach to the field of androgen excess or deprivation in women's health. The content includes multiple viewpoints on the most common disorders in this class, such as polycystic ovary disease, hirsutism and menopausal issues. Each chapter provides a combination of long-lasting clinical principles in the diagnosis and management of these patients along with a state-of-the-art review. This text takes an innovative approach to uncommon conditions (such as congenital adrenal hyperplasia, transgender conditions). In addition to presenting clinical insights, and a review of the basic science underpinning these conditions, it focuses on key concepts that can be derived from these rare conditions to the entire field. This book is an essential addition to the library for any busy clinician who is looking for a practical reference guide but also for the sub-specialist who is looking for new and thought-provoking insights in this complex scientific area.
Download or read book Polycystic Ovary Syndrome written by Andrea Dunaif and published by Springer Science & Business Media. This book was released on 2008-01-12 with total page 361 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume includes the latest diagnostic criteria for PCOS and comprises the most up-to-date information about the genetic features and pathogenesis of PCOS. It critically reviews the methodological approaches and the evidence for various PCOS susceptibility genes. The book also discusses additional familial phenotypes of PCOS and their potential genetic basis. All four editors of this title are extremely prominent in the field of PCOS.
Download or read book Cushing s Disease written by Brooke Swearingen and published by Springer Science & Business Media. This book was released on 2011-09-08 with total page 267 pages. Available in PDF, EPUB and Kindle. Book excerpt: In Cushing’s Disease, leading authorities in the field offer a thorough review of the pathogenesis, diagnostic algorithm and treatment options for this complex disease. Beginning with a fascinating history of Cushing's disease that outlines its historical significance to both endocrinology and neurosurgery, the book goes onto to cover the full range of important issues, including the molecular pathogenesis of Cushing’s, anatomic pathology, the diagnosis of Cushing's syndrome, the differential of pseudo-Cushing's syndromes, hypercortisolemia, surgical removal of the corticotroph adenoma, post-operative management and assessment of remission, radiotherapeutic options, and the exciting developments in medical therapy. In addition, the book also addresses Cushing's disease in the pediatric population, given that its clinical manifestations and impact on growth can be severe; silent corticotroph adenomas as a distinct clinical entity; diagnosis and management of Cushing's disease during pregnancy, bilateral adrenalectomy, and, finally, the long-term psychological manifestations of hypercortisolemia. Comprehensive and an invaluable addition the literature, Cushing’s Disease is an essential reference for enhancing diagnosis and treatment of this debilitating disorder.
Download or read book Clinical Algorithms in General Surgery written by Salvatore Docimo Jr. and published by Springer. This book was released on 2019-02-04 with total page 786 pages. Available in PDF, EPUB and Kindle. Book excerpt: As the field of general surgery continues to expand, the diagnostic and therapeutic pathways are becoming more complex. The diagnostic modalities available to the clinician can be both very helpful but also overwhelming considering the findings can often determine the scope of treatment for a patient. This text will take the major pathologies of the systems commonly studied in general surgery and present them in a unique format based upon algorithms. The algorithms will begin with the clinical presentation of the patient, work its way through the various diagnostic modalities available to the surgeon, and finally allow the physician to make a decision regarding treatment options based upon various patterns in the algorithms. This text will become a very useful resources for surgeons as it allows complex clinical pathways to be conveniently organized in logical algorithms. It will become a concise yet comprehensive manual to assist in clinical decision making. All algorithms will be reviewed by experts in their field and include the most up-to-date clinical and evidence-based information. Clinical Algorithms in General Surgery provides a useful resource for surgeons in clinical practice as well as surgical residents, and surgical attendings who are preparing for board examinations. See sample algorithm in Attachments.
Download or read book Adrenal Disorders written by Andrew N. Margioris and published by PennWell Corporation. This book was released on 2001-04-20 with total page 444 pages. Available in PDF, EPUB and Kindle. Book excerpt: In Adrenal Disorders, a panel of distinguished physicians and researchers select the most relevant new findings and integrate them into the existing body of clinical knowledge on adrenal pathologies. The book includes important reviews of disturbances in cortisol homeostasis, and new concepts regarding adrenal tumors and hereditary adrenal diseases. Also discussed are mineralocorticoids and the syndromes of mineralocortoid excess and aldosterone synthase deficiency. Authoritative and insightful, Adrenal Disorders provides physicians and scientists with a comprehensive, state-of-the-art practical guide to the devastating diseases of the adrenals that are so often difficult to diagnose and treat.
Download or read book Cushing s Syndrome written by D. T. Krieger and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 249 pages. Available in PDF, EPUB and Kindle. Book excerpt: The unraveling of our knowledge of the functions of the adrenal gland constitutes one exciting development of modern medicine and biochemistry. We owe these advances to the felicitous cooperative efforts of the clinical investigator and the biochemist. Three centuries elapsed between the first recorded anatomical descrip tion of the adrenals and the demonstration by Dr. Addison in the mid-nineteenth century of the fatal results of the destruction of these glands by disease. It became evident from this observation that the adrenals secreted a "factor" or "factors" essential to life. It took approximately 90 years to isolate this elusive vital factor - cortisone - from beef adrenal cortices, independently by both Reichstein and his co-workers in Basle and Kendall and his group in the United States and another 10-15 years before it became more generally available for experimental and clinical use. It is perhaps difficult to believe that as recently as 35-40 years ago, before cortisone and cortisol were clinically available, the surgical removal of a benign adrenal cortical tumor in patients with Cushing's syndrome was associated with a prohibitive postoperative mortality rate. Within 12-36 h after operation, most of such patients developed an intractable state of shock, which was not manifested by significant electrolyte abnormalities or hypoglycemia and was unresponsive to the usual treatment for shock plus the generous use of salt-retaining hormone.
Download or read book Cushing s Syndrome written by Lewis S. Blevins and published by Springer Science & Business Media. This book was released on 2002-09-30 with total page 368 pages. Available in PDF, EPUB and Kindle. Book excerpt: Cushing's Syndrome provides the reader with an update on the clinical presentation, diagnosis, and treatment of patients with Cushing's syndrome. Molecular mechanisms of pituitary and adrenal causes of Cushing's syndrome are reviewed in detail. Successful diagnostic and treatment strategies that have been employed by readers in the field are recommended and discussed. Numerous advances in the pathophysiology and diagnosis of Cushing's syndrome speak to the timeliness of this volume that has been penned by experts in the field.
Download or read book The Hypothalamus Pituitary Adrenal Axis written by and published by Elsevier. This book was released on 2008-09-12 with total page 413 pages. Available in PDF, EPUB and Kindle. Book excerpt: The hypothalamic-pituitary-adrenal axis controls reactions to stress and regulates various body processes such as digestion, the immune system, mood and sexuality, and energy usage. This volume focuses on the role it plays in the immune system and provides substantive experimental and clinical data to support current understanding in the field, and potential applications of this knowledge in the treatment of disease. Evidence presented in this book suggests that the nervous, endocrine, and immune systems form the Neuroendoimmune Supersystem, which integrates all the biological functions of higher organisms both in health and disease for their entire life cycle Contributors include both the scientists who initiated the work on the HPA axis and on the autonomic nervous system, and those who joined the field later
Download or read book Cushing s Syndrome written by Dorothy T. Krieger and published by Springer. This book was released on 1982 with total page 164 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Pituitary Microadenomas written by G. Faglia and published by . This book was released on 1980 with total page 588 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book The Cushing s Syndrome Diet written by Stan Underhill and published by CreateSpace. This book was released on 2010-06-10 with total page 126 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Cushing's Syndrome Diet is filled with no nonsense recipes that will help control your Cushing's Syndrome symptoms. While there are many treatment options for Cushing's, only one is vital to insuring your overall health: a balanced, nutritional diet, low in salt and fat and high in protein and calcium. This type of diet can slow or prevent the loss of muscle and bone from Cushing's Syndrome. You'll find all of the recipes in this book provide you with maximum nutritional from plant sources-and they are quick and easy to prepare, so you can get back to living your life!
Download or read book Disorders of Blood Pressure Regulation written by Adel E. Berbari and published by Springer. This book was released on 2018-01-25 with total page 880 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book aims to present a comprehensive classification of hypertensive phenotypes based on underlying target organ involvement. Particular emphasis is placed on review and assessment of clinical presentation, pathophysiologic mechanisms, and possible specific therapeutic options for each hypertension phenotype. Several of these phenotypes are well known and well described in the literature, such as prehypertension, white coat and masked hypertension, isolated systolic hypertension, renovascular hypertension, endocrine hypertension, pediatric hypertension, and gestational hypertension. Other hypertension phenotypes, however, are not widely recognized, being reported only in special reviews; examples include hypertension associated with renal calculus disease and other rarer causes such as Turner syndrome, herbal and medicinal compounds, and pharmacologic agents. A detailed account of the various causes of monogenic hypertension is also included. Finally, a section is devoted to general aspects of hypertension, including the significance of blood pressure indices, the natural course of untreated and treated hypertension, hypertension mechanisms, genetics, and guidelines for blood pressure control.
Download or read book The Pituitary Body and Its Disorders written by Harvey Cushing and published by . This book was released on 1912 with total page 368 pages. Available in PDF, EPUB and Kindle. Book excerpt: This work includes Cushing's description of his own method of operating on the pituitary. He was an outstanding neurological surgeon and added much to our knowledgeof the pituitary body and its disorders.
Download or read book The Hypothalamic Pituitary Adrenal Axis in Health and Disease written by Eliza B. Geer and published by Springer. This book was released on 2016-12-01 with total page 323 pages. Available in PDF, EPUB and Kindle. Book excerpt: Cushing ́s syndrome is a rare disorder that is associated with many co-morbidities such as systemic hypertension, diabetes, osteoporosis, impaired immune function, and psychiatric disease, all of which severely reduce quality of life and life expectancy. This book reviews the role of cortisol in the human body, focusing on the effects of excess cortisol due to Cushing’s syndrome as well as the role of the HPA axis in metabolism, inflammation, and neuropsychiatric function. The volume will cover basic mechanistic data, clinical outcomes data, and novel therapies. Also discussed are everything from abnormalities of the HPA axis, to the role of the HPA axis in the development of neuropsychiatric disorders and metabolic disorders, to new definitions of Cushing’s remission and recurrence. The Hypothalamic Pituitary Adrenal Axis in Health and Disease will provide a comprehensive and multi-disciplinary review of the pathophysiology and outcomes of excess cortisol in the human body and brain as well as the role of the HPA axis in other disease states.
