Download or read book Homology Genes and Evolutionary Innovation written by Günter P. Wagner and published by Princeton University Press. This book was released on 2018-07-10 with total page 494 pages. Available in PDF, EPUB and Kindle. Book excerpt: A major synthesis of homology, written by a top researcher in the field Homology—a similar trait shared by different species and derived from common ancestry, such as a seal's fin and a bird’s wing—is one of the most fundamental yet challenging concepts in evolutionary biology. This groundbreaking book provides the first mechanistically based theory of what homology is and how it arises in evolution. Günter Wagner, one of the preeminent researchers in the field, argues that homology, or character identity, can be explained through the historical continuity of character identity networks—that is, the gene regulatory networks that enable differential gene expression. He shows how character identity is independent of the form and function of the character itself because the same network can activate different effector genes and thus control the development of different shapes, sizes, and qualities of the character. Demonstrating how this theoretical model can provide a foundation for understanding the evolutionary origin of novel characters, Wagner applies it to the origin and evolution of specific systems, such as cell types; skin, hair, and feathers; limbs and digits; and flowers. The first major synthesis of homology to be published in decades, Homology, Genes, and Evolutionary Innovation reveals how a mechanistically based theory can serve as a unifying concept for any branch of science concerned with the structure and development of organisms, and how it can help explain major transitions in evolution and broad patterns of biological diversity.
Download or read book Deep Homology written by Lewis I. Held, Jr and published by Cambridge University Press. This book was released on 2017-02-16 with total page 291 pages. Available in PDF, EPUB and Kindle. Book excerpt: A comparison of the genetic circuits of Homo sapiens and Drosophila reveals the evidence for deep homology.
Download or read book Sequence Evolution Function written by Eugene V. Koonin and published by Springer Science & Business Media. This book was released on 2013-06-29 with total page 482 pages. Available in PDF, EPUB and Kindle. Book excerpt: Sequence - Evolution - Function is an introduction to the computational approaches that play a critical role in the emerging new branch of biology known as functional genomics. The book provides the reader with an understanding of the principles and approaches of functional genomics and of the potential and limitations of computational and experimental approaches to genome analysis. Sequence - Evolution - Function should help bridge the "digital divide" between biologists and computer scientists, allowing biologists to better grasp the peculiarities of the emerging field of Genome Biology and to learn how to benefit from the enormous amount of sequence data available in the public databases. The book is non-technical with respect to the computer methods for genome analysis and discusses these methods from the user's viewpoint, without addressing mathematical and algorithmic details. Prior practical familiarity with the basic methods for sequence analysis is a major advantage, but a reader without such experience will be able to use the book as an introduction to these methods. This book is perfect for introductory level courses in computational methods for comparative and functional genomics.
Download or read book Handbook of Paleoanthropology written by Winfried Henke and published by Springer Science & Business Media. This book was released on 2007-05-10 with total page 2057 pages. Available in PDF, EPUB and Kindle. Book excerpt: This 3-volume handbook brings together contributions by the world ́s leading specialists that reflect the broad spectrum of modern palaeoanthropology, thus presenting an indispensable resource for professionals and students alike. Vol. 1 reviews principles, methods, and approaches, recounting recent advances and state-of-the-art knowledge in phylogenetic analysis, palaeoecology and evolutionary theory and philosophy. Vol. 2 examines primate origins, evolution, behaviour, and adaptive variety, emphasizing integration of fossil data with contemporary knowledge of the behaviour and ecology of living primates in natural environments. Vol. 3 deals with fossil and molecular evidence for the evolution of Homo sapiens and its fossil relatives.
Download or read book Molecular Biology of the Cell written by and published by . This book was released on 2002 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Biological Sequence Analysis written by Richard Durbin and published by Cambridge University Press. This book was released on 1998-04-23 with total page 372 pages. Available in PDF, EPUB and Kindle. Book excerpt: Probabilistic models are becoming increasingly important in analysing the huge amount of data being produced by large-scale DNA-sequencing efforts such as the Human Genome Project. For example, hidden Markov models are used for analysing biological sequences, linguistic-grammar-based probabilistic models for identifying RNA secondary structure, and probabilistic evolutionary models for inferring phylogenies of sequences from different organisms. This book gives a unified, up-to-date and self-contained account, with a Bayesian slant, of such methods, and more generally to probabilistic methods of sequence analysis. Written by an interdisciplinary team of authors, it aims to be accessible to molecular biologists, computer scientists, and mathematicians with no formal knowledge of the other fields, and at the same time present the state-of-the-art in this new and highly important field.
Download or read book Computational Protein Design written by Ilan Samish and published by Humana. This book was released on 2016-12-03 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: The aim this volume is to present the methods, challenges, software, and applications of this widespread and yet still evolving and maturing field. Computational Protein Design, the first book with this title, guides readers through computational protein design approaches, software and tailored solutions to specific case-study targets. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Authoritative and cutting-edge, Computational Protein Design aims to ensure successful results in the further study of this vital field.
Download or read book The Evolution of Phylogenetic Systematics written by Andrew Hamilton and published by Univ of California Press. This book was released on 2013-11-09 with total page 320 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Evolution of Phylogenetic Systematics aims to make sense of the rise of phylogenetic systematics—its methods, its objects of study, and its theoretical foundations—with contributions from historians, philosophers, and biologists. This volume articulates an intellectual agenda for the study of systematics and taxonomy in a way that connects classification with larger historical themes in the biological sciences, including morphology, experimental and observational approaches, evolution, biogeography, debates over form and function, character transformation, development, and biodiversity. It aims to provide frameworks for answering the question: how did systematics become phylogenetic?
Download or read book Homology Modeling written by Andrew J. W. Orry and published by Humana Press. This book was released on 2012-02-10 with total page 419 pages. Available in PDF, EPUB and Kindle. Book excerpt: Knowledge about protein tertiary structure can guide experiments, assist in the understanding of structure-function relationships, and aid the design of new therapeutics for disease. Homology modeling is an in silico method that predicts the tertiary structure of an amino acid sequence based on a homologous experimentally determined structure. In, Homology Modelling: Methods and Protocols experts in the field describe each homology modeling step from first principles, provide case studies for challenging modeling targets and describe methods for the prediction of how other molecules such as drugs can interact with the protein. Written in the highly successful Methods in Molecular BiologyTM series format, the chapters include the kind of detailed description and implementation advice that is crucial for getting optimal results in the laboratory. Thorough and intuitive, Homology Modelling: Methods and Protocols guides scientists in the available homology modeling methods.
Download or read book The Philosophy of Biology written by Kostas Kampourakis and published by Springer Science & Business Media. This book was released on 2013-06-18 with total page 765 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book brings together for the first time philosophers of biology to write about some of the most central concepts and issues in their field from the perspective of biology education. The chapters of the book cover a variety of topics ranging from traditional ones, such as biological explanation, biology and religion or biology and ethics, to contemporary ones, such as genomics, systems biology or evolutionary developmental biology. Each of the 30 chapters covers the respective philosophical literature in detail and makes specific suggestions for biology education. The aim of this book is to inform biology educators, undergraduate and graduate students in biology and related fields, students in teacher training programs, and curriculum developers about the current state of discussion on the major topics in the philosophy of biology and its implications for teaching biology. In addition, the book can be valuable to philosophers of biology as an introductory text in undergraduate and graduate courses.
Download or read book Concepts of Biology written by Samantha Fowler and published by . This book was released on 2023-05-12 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Black & white print. Concepts of Biology is designed for the typical introductory biology course for nonmajors, covering standard scope and sequence requirements. The text includes interesting applications and conveys the major themes of biology, with content that is meaningful and easy to understand. The book is designed to demonstrate biology concepts and to promote scientific literacy.
Download or read book Icons of Evolution written by Jonathan Wells and published by Simon and Schuster. This book was released on 2002-01-01 with total page 251 pages. Available in PDF, EPUB and Kindle. Book excerpt: Everything you were taught about evolution is wrong.
Download or read book The Evolutionary Biology of Human Female Sexuality written by Randy Thornhill and published by Oxford University Press. This book was released on 2008 with total page 422 pages. Available in PDF, EPUB and Kindle. Book excerpt: This title introduces a theoretical framework for understanding women's sexuality based on comparative female sexuality across all vertebrate animals. It shows that estrus is present in human females, contrary to earlier research.
Download or read book Homology Molecular Modeling written by Rafael Trindade Maia and published by BoD – Books on Demand. This book was released on 2021-03-10 with total page 147 pages. Available in PDF, EPUB and Kindle. Book excerpt: Homology modeling is an extremely useful and versatile technique that is gaining more and more space and demand in research in computational and theoretical biology. This book, “Homology Molecular Modeling - Perspectives and Applications”, brings together unpublished chapters on this technique. In this book, 7 chapters are intimately related to the theme of molecular modeling, carefully selected and edited for academic and scientific readers. It is an indispensable read for anyone interested in the areas of bioinformatics and computational biology. Divided into 4 sections, the reader will have a didactic and comprehensive view of the theme, with updated and relevant concepts on the subject. This book was organized from researchers to researchers with the aim of spreading the fascinating area of molecular modeling by homology.
Download or read book On the Nature of Limbs written by Richard Owen and published by University of Chicago Press. This book was released on 2008-11-15 with total page 231 pages. Available in PDF, EPUB and Kindle. Book excerpt: The most prominent naturalist in Britain before Charles Darwin, Richard Owen made empirical discoveries and offered theoretical innovations that were crucial to the proof of evolution. Among his many lasting contributions to science was the first clear definition of the term homology—“the same organ in different animals under every variety of form and function.” He also graphically demonstrated that all vertebrate species were built on the same skeletal plan and devised the vertebrate archetype as a representation of the simplest common form of all vertebrates. Just as Darwin’s ideas continue to propel the modern study of adaptation, so too will Owen’s contributions fuel the new interest in homology, organic form, and evolutionary developmental biology. His theory of the archetype and his views on species origins were first offered to the general public in On the Nature of Limbs, published in 1849. It reemerges here in a facsimile edition with introductory essays by prominent historians, philosophers, and practitioners from the modern evo-devo community.
Download or read book Origination of Organismal Form written by Gerd B. Muller and published by MIT Press. This book was released on 2003-01-03 with total page 354 pages. Available in PDF, EPUB and Kindle. Book excerpt: A more comprehensive version of evolutionary theory that focuses as much on the origin of biological form as on its diversification. The field of evolutionary biology arose from the desire to understand the origin and diversity of biological forms. In recent years, however, evolutionary genetics, with its focus on the modification and inheritance of presumed genetic programs, has all but overwhelmed other aspects of evolutionary biology. This has led to the neglect of the study of the generative origins of biological form. Drawing on work from developmental biology, paleontology, developmental and population genetics, cancer research, physics, and theoretical biology, this book explores the multiple factors responsible for the origination of biological form. It examines the essential problems of morphological evolution—why, for example, the basic body plans of nearly all metazoans arose within a relatively short time span, why similar morphological design motifs appear in phylogenetically independent lineages, and how new structural elements are added to the body plan of a given phylogenetic lineage. It also examines discordances between genetic and phenotypic change, the physical determinants of morphogenesis, and the role of epigenetic processes in evolution. The book discusses these and other topics within the framework of evolutionary developmental biology, a new research agenda that concerns the interaction of development and evolution in the generation of biological form. By placing epigenetic processes, rather than gene sequence and gene expression changes, at the center of morphological origination, this book points the way to a more comprehensive theory of evolution.
Download or read book Evolutionary Developmental Biology written by Laura Nuno de la Rosa and published by Springer. This book was released on 2020-11-15 with total page 1000 pages. Available in PDF, EPUB and Kindle. Book excerpt: This reference work provides an comprehensive and easily accessible source of information on numerous aspects of Evolutionary Developmental Biology. The work provides an extended overview on the current state of the art of this interdisciplinary and dynamic scientific field. The work is organized in thematic sections, referring to the specific requirements and interests in each section in far detail. “Evolutionary Developmental Biology – A Reference Guide” is intended to provide a resource of knowledge for researchers engaged in evolutionary biology, developmental biology, theoretical biology, philosophy of sciences and history of biology.
