Download or read book La escalera de Jacob written by Henry Gee and published by Grupo Planeta (GBS). This book was released on 2006 with total page 244 pages. Available in PDF, EPUB and Kindle. Book excerpt: La escalera de Jacob nos ofrece una explicación lúcida y sencilla de lo que realmente nos revela la secuenciación del genoma humano. El biólogo evolutivo Henry Gee muestra que conocer la secuenciación es sólo el comienzo de una gran aventura, como ver las letras y las palabras en el acto de leer. La próxima frontera es comprender fragmentos de las conversaciones entre los genes: cómo interactúan para dirigir el crecimiento de un organismo. El autor nos lleva al núcleo de esa conversación, aclarando cómo los genes gobiernan la milagrosa transformación de una única célula madre en un ser humano y cómo continúan dirigiendo el desarrollo diario de esa persona durante el resto de su vida. Gee nos cuenta la historia de lo que sabemos sobre el genoma y lo que es probable que descubramos en un futuro más o menos próximo. A medida que avancen nuestros conocimientos, seremos capaces de dirigir con creciente autoridad las conversaciones entre los genes, no sólo realizando intervenciones médicas, sino creando guiones enteros sobre el nacimiento, la descendencia y la diversidad en un nuevo mundo feliz.
Download or read book The Gene written by Siddhartha Mukherjee and published by Simon and Schuster. This book was released on 2016-05-17 with total page 624 pages. Available in PDF, EPUB and Kindle. Book excerpt: The #1 NEW YORK TIMES Bestseller The basis for the PBS Ken Burns Documentary The Gene: An Intimate History Now includes an excerpt from Siddhartha Mukherjee’s new book Song of the Cell! From the Pulitzer Prize–winning author of The Emperor of All Maladies—a fascinating history of the gene and “a magisterial account of how human minds have laboriously, ingeniously picked apart what makes us tick” (Elle). “Sid Mukherjee has the uncanny ability to bring together science, history, and the future in a way that is understandable and riveting, guiding us through both time and the mystery of life itself.” —Ken Burns “Dr. Siddhartha Mukherjee dazzled readers with his Pulitzer Prize-winning The Emperor of All Maladies in 2010. That achievement was evidently just a warm-up for his virtuoso performance in The Gene: An Intimate History, in which he braids science, history, and memoir into an epic with all the range and biblical thunder of Paradise Lost” (The New York Times). In this biography Mukherjee brings to life the quest to understand human heredity and its surprising influence on our lives, personalities, identities, fates, and choices. “Mukherjee expresses abstract intellectual ideas through emotional stories…[and] swaddles his medical rigor with rhapsodic tenderness, surprising vulnerability, and occasional flashes of pure poetry” (The Washington Post). Throughout, the story of Mukherjee’s own family—with its tragic and bewildering history of mental illness—reminds us of the questions that hang over our ability to translate the science of genetics from the laboratory to the real world. In riveting and dramatic prose, he describes the centuries of research and experimentation—from Aristotle and Pythagoras to Mendel and Darwin, from Boveri and Morgan to Crick, Watson and Franklin, all the way through the revolutionary twenty-first century innovators who mapped the human genome. “A fascinating and often sobering history of how humans came to understand the roles of genes in making us who we are—and what our manipulation of those genes might mean for our future” (Milwaukee Journal-Sentinel), The Gene is the revelatory and magisterial history of a scientific idea coming to life, the most crucial science of our time, intimately explained by a master. “The Gene is a book we all should read” (USA TODAY).
Download or read book Gene Machine written by Venki Ramakrishnan and published by Basic Books. This book was released on 2018-11-06 with total page 290 pages. Available in PDF, EPUB and Kindle. Book excerpt: A Nobel Prize-winning biologist tells the riveting story of his race to discover the inner workings of biology's most important molecule "Ramakrishnan's writing is so honest, lucid and engaging that I could not put this book down until I had read to the very end." -- Siddhartha Mukherjee, author of The Emperor of All Maladies and The Gene Everyone has heard of DNA. But by itself, DNA is just an inert blueprint for life. It is the ribosome -- an enormous molecular machine made up of a million atoms -- that makes DNA come to life, turning our genetic code into proteins and therefore into us. Gene Machine is an insider account of the race for the structure of the ribosome, a fundamental discovery that both advances our knowledge of all life and could lead to the development of better antibiotics against life-threatening diseases. But this is also a human story of Ramakrishnan's unlikely journey, from his first fumbling experiments in a biology lab to being the dark horse in a fierce competition with some of the world's best scientists. In the end, Gene Machine is a frank insider's account of the pursuit of high-stakes science.
Download or read book The Laws of Medicine written by Siddhartha Mukherjee and published by Simon and Schuster. This book was released on 2015-10-13 with total page 96 pages. Available in PDF, EPUB and Kindle. Book excerpt: Essential, required reading for doctors and patients alike: A Pulitzer Prize-winning author and one of the world’s premiere cancer researchers reveals an urgent philosophy on the little-known principles that govern medicine—and how understanding these principles can empower us all. Over a decade ago, when Siddhartha Mukherjee was a young, exhausted, and isolated medical resident, he discovered a book that would forever change the way he understood the medical profession. The book, The Youngest Science, forced Dr. Mukherjee to ask himself an urgent, fundamental question: Is medicine a “science”? Sciences must have laws—statements of truth based on repeated experiments that describe some universal attribute of nature. But does medicine have laws like other sciences? Dr. Mukherjee has spent his career pondering this question—a question that would ultimately produce some of most serious thinking he would do around the tenets of his discipline—culminating in The Laws of Medicine. In this important treatise, he investigates the most perplexing and illuminating cases of his career that ultimately led him to identify the three key principles that govern medicine. Brimming with fascinating historical details and modern medical wonders, this important book is a fascinating glimpse into the struggles and Eureka! moments that people outside of the medical profession rarely see. Written with Dr. Mukherjee’s signature eloquence and passionate prose, The Laws of Medicine is a critical read, not just for those in the medical profession, but for everyone who is moved to better understand how their health and well-being is being treated. Ultimately, this book lays the groundwork for a new way of understanding medicine, now and into the future.
Download or read book History of Human Genetics written by Heike I. Petermann and published by Springer. This book was released on 2017-05-10 with total page 562 pages. Available in PDF, EPUB and Kindle. Book excerpt: Written by 30 authors from all over the world, this book provides a unique overview of exciting discoveries and surprising developments in human genetics over the last 50 years. The individual contributions, based on seven international workshops on the history of human genetics, cover a diverse range of topics, including the early years of the discipline, gene mapping and diagnostics. Further, they discuss the status quo of human genetics in different countries and highlight the value of genetic counseling as an important subfield of medical genetics.
Download or read book Who We Are and How We Got Here written by David Reich and published by Oxford University Press. This book was released on 2018-03-29 with total page 320 pages. Available in PDF, EPUB and Kindle. Book excerpt: The past few years have witnessed a revolution in our ability to obtain DNA from ancient humans. This important new data has added to our knowledge from archaeology and anthropology, helped resolve long-existing controversies, challenged long-held views, and thrown up remarkable surprises. The emerging picture is one of many waves of ancient human migrations, so that all populations living today are mixes of ancient ones, and often carry a genetic component from archaic humans. David Reich, whose team has been at the forefront of these discoveries, explains what genetics is telling us about ourselves and our complex and often surprising ancestry. Gone are old ideas of any kind of racial âpurity.' Instead, we are finding a rich variety of mixtures. Reich describes the cutting-edge findings from the past few years, and also considers the sensitivities involved in tracing ancestry, with science sometimes jostling with politics and tradition. He brings an important wider message: that we should recognize that every one of us is the result of a long history of migration and intermixing of ancient peoples, which we carry as ghosts in our DNA. What will we discover next?
Download or read book Into Another s Skin Selected Essays in Honour of Mar a Luisa Da obeitia written by María José de la Torre Moreno and published by Mauricio D. Aguilera Linde. This book was released on 2012-02-20 with total page 287 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Prehistoric Iberia written by Antonio Arnaiz-Villena and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 270 pages. Available in PDF, EPUB and Kindle. Book excerpt: The symposium "Prehistoric Iberia: genetics, anthropology and linguistics" was held in the Circulo de Bellas Artes, Madrid on 16th -17th November 1998. The idea was bringing together specialists who could address not clearly resolved historic and prehistoric issues regarding ancient Iberian and Mediterranean populations, following a multidisciplinary approach. This was necessary in the light of the new bulk of genetic, archeological and linguistic data obtained with the new DNA technology and the recent discoverings in the other fields. Genes may now be easily studied in populations, particularly HLA genes and markers of the mitochondrial DNA and the Y chromosome. Basques, Iberians, North Africans, Berbers (Imazighen) and Mediterraneans have presently been widely studied. The genetic emerging picture is that Mediterraneans are closely related from West (Basque, Iberians, Berbers) to East (Jews, Lebanese, Cretans); however, Greeks are outliers in all the analyses done by using HLA genes. Anthropologists and archeologists showed how there was no people substitution during the revolutionary Mesolithic-Neolithic transition; in addition, cultural relationships were found between Iberia and predinastic Egypt (EI Badari culture). Basque language translation into Spanish has been the key for relating most Mediterranean extinct languages. The Usko-Mediterranean languages were once spoken in a wide African and European area, which also included parts of Asia. This was the "old language" that was slowly substituted by Eurasian languages starting approximately after the Bronze Age (or 2,000 years BC).
Download or read book Spatial Information Theory written by Andrew U. Frank and published by Springer Science & Business Media. This book was released on 1995-09-13 with total page 1074 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book constitutes the refereed proceedings of the International Conference on Spatial Information Theory, COSIT'95, held near Vienna, Austria, in September 1995. Spatial Information Theory brings together three fields of research of paramount importance for geographic information systems technology, namely spatial reasoning, representation of space, and human understanding of space. The book contains 36 fully revised papers selected from a total of 78 submissions and gives a comprehensive state-of-the-art report on this exciting multidisciplinary - and highly interdisciplinary - area of research and development.
Download or read book Experiments in Plant Hybridisation written by Gregor Mendel and published by Cosimo, Inc.. This book was released on 2008-11-01 with total page 54 pages. Available in PDF, EPUB and Kindle. Book excerpt: Experiments which in previous years were made with ornamental plants have already afforded evidence that the hybrids, as a rule, are not exactly intermediate between the parental species. With some of the more striking characters, those, for instance, which relate to the form and size of the leaves, the pubescence of the several parts, etc., the intermediate, indeed, is nearly always to be seen; in other cases, however, one of the two parental characters is so preponderant that it is difficult, or quite impossible, to detect the other in the hybrid. from 4. The Forms of the Hybrid One of the most influential and important scientific works ever written, the 1865 paper Experiments in Plant Hybridisation was all but ignored in its day, and its author, Austrian priest and scientist GREGOR JOHANN MENDEL (18221884), died before seeing the dramatic long-term impact of his work, which was rediscovered at the turn of the 20th century and is now considered foundational to modern genetics. A simple, eloquent description of his 18561863 study of the inheritance of traits in pea plantsMendel analyzed 29,000 of themthis is essential reading for biology students and readers of science history. Cosimo presents this compact edition from the 1909 translation by British geneticist WILLIAM BATESON (18611926).
Download or read book Historical Dictionary of Chile written by Salvatore Bizzarro and published by Scarecrow Press. This book was released on 2005-04-20 with total page 1003 pages. Available in PDF, EPUB and Kindle. Book excerpt: Surveys the radical changes that have occurred in recent years in every aspect of Chilean life. Features more than 3,000 dictionary entries covering history, politics, geography, economics, the environment, culture, and a myriad other topics that include writers, artists, playwrights, and important figures, many of which were not included in the previous edition. Also included are 24 photographs of the paintings of famous Latin American artists, and an exhaustive bibliography of more than 1,200 resources subdivided by topic and fully annotated.
Download or read book The Best American Science Writing 2000 written by James Gleick and published by Ecco. This book was released on 2000-09-05 with total page 272 pages. Available in PDF, EPUB and Kindle. Book excerpt: The first volume in this annual series of the best writing by Americans, meticulously selected by bestselling author James Gleick, one of the foremost chronicles of scientific social history, debuts with a stellar collection of writers and thinkers. Many of these cutting-edge essays offer glimpses of new realms of discovery and thought, exploring territory that is unfamiliar to most of us, or finding the unexpected in the midst of the familiar. Nobel Laureate physicist Steven Weinberg challenges the idea of whether the universe has a designer; Pulitzer Prize winner Natalie Angier reassesses caveman (and-woman) couture; bestselling author and Darwinian theorist Stephen Jay Gould makes a claim for the man whose ideas Darwin discredited; Timothy Ferris proposes a realistic alternative to wrap-speed interseller travel; neurologist and bestselling author Oliver Sacks reminisces about his first loves-chemistry and math. This diverse, stimulating and accessible collection is required reading for anyone who wants to travel to the frontier of knowledge.
Download or read book Life in Search of Readers written by Manuel M. Martín-Rodríguez and published by UNM Press. This book was released on 2003 with total page 252 pages. Available in PDF, EPUB and Kindle. Book excerpt: In this examination of Chicano/a literature, Manuel M. Martin-Rodriguez analyzes the ways it connects with and is shaped by the interaction with its audiences.
Download or read book Current Catalog written by National Library of Medicine (U.S.) and published by . This book was released on 1982 with total page 1174 pages. Available in PDF, EPUB and Kindle. Book excerpt: First multi-year cumulation covers six years: 1965-70.
Download or read book A Catalogue of the Library Collected by Miss Richardson Currer at Eshton Hall Craven Yorkshire written by Frances Mary Richardson Currer and published by . This book was released on 1833 with total page 548 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book The Epigenetics Revolution written by Nessa Carey and published by Columbia University Press. This book was released on 2012-03-06 with total page 353 pages. Available in PDF, EPUB and Kindle. Book excerpt: Epigenetics can potentially revolutionize our understanding of the structure and behavior of biological life on Earth. It explains why mapping an organism's genetic code is not enough to determine how it develops or acts and shows how nurture combines with nature to engineer biological diversity. Surveying the twenty-year history of the field while also highlighting its latest findings and innovations, this volume provides a readily understandable introduction to the foundations of epigenetics. Nessa Carey, a leading epigenetics researcher, connects the field's arguments to such diverse phenomena as how ants and queen bees control their colonies; why tortoiseshell cats are always female; why some plants need cold weather before they can flower; and how our bodies age and develop disease. Reaching beyond biology, epigenetics now informs work on drug addiction, the long-term effects of famine, and the physical and psychological consequences of childhood trauma. Carey concludes with a discussion of the future directions for this research and its ability to improve human health and well-being.
Download or read book Inequality written by Carles Lalueza-Fox and published by MIT Press. This book was released on 2023-09-19 with total page 187 pages. Available in PDF, EPUB and Kindle. Book excerpt: How genomics reveals deep histories of inequality, going back many thousands of years. Inequality is an urgent global concern, with pundits, politicians, academics, and best-selling books all taking up its causes and consequences. In Inequality, Carles Lalueza-Fox offers an entirely new perspective on the subject, examining the genetic marks left by inequality on humans throughout history. Lalueza-Fox describes genetic studies, made possible by novel DNA sequencing technologies, that reveal layers of inequality in past societies, manifested in patterns of migration, social structures, and funerary practices. Through their DNA, ancient skeletons have much to tell us, yielding anonymous stories of inequality, bias, and suffering. Lalueza-Fox, a leader in paleogenomics, offers the deep history of inequality. He explores the ancestral shifts associated with migration and describes the gender bias unearthed in these migrations—the brutal sexual asymmetries, for example, between male European explorers and the women of Latin America that are revealed by DNA analysis. He considers social structures, and the evidence that high social standing was inherited—the ancient world was not a meritocracy. He untangles social and genetic factors to consider whether wealth is an advantage in reproduction, showing why we are more likely to be descended from a king than a peasant. And he explores the effects of ancient inequality on the human gene pool. Marshaling a range of evidence, Lalueza-Fox shows that understanding past inequalities is key to understanding present ones.
