Download or read book High Fat Feeding and Obesity in Rats written by Niloofar Hariri and published by . This book was released on 2010 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Fat Detection written by Jean-Pierre Montmayeur and published by CRC Press. This book was released on 2009-09-14 with total page 646 pages. Available in PDF, EPUB and Kindle. Book excerpt: Presents the State-of-the-Art in Fat Taste TransductionA bite of cheese, a few potato chips, a delectable piece of bacon - a small taste of high-fat foods often draws you back for more. But why are fatty foods so appealing? Why do we crave them? Fat Detection: Taste, Texture, and Post Ingestive Effects covers the many factors responsible for the se
Download or read book Nutrition in Pediatrics written by Christopher Duggan, MD, MPH and published by PMPH USA, Ltd. This book was released on 2016-06-21 with total page 2843 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Drug Discovery and Evaluation Pharmacological Assays written by Franz J. Hock and published by Springer. This book was released on 2015-11-14 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: The 4th edition of this successful reference book contains an updated selection of the most frequently used assays for reliably detecting the pharmacological effects of potential drugs. Effects covered include cardiovascular, analgesic, endocrine, psychotropic, respiratory, renal and immunomodulatory activities. Each of the more than 1,000 assays comprises a detailed protocol outlining the purpose and rationale of the method, a critical assessment of the results and their pharmacological and clinical relevance. In addition, animal models of rare diseases are described. For this 4th edition, all existing chapters have been revised and completely updated. A large number of assays were added. Sections that have been specifically enlarged include - Pharmacological assays in thrombosis and haemostasis, - Antidiabetic activity (includes completely new chapters such as Biochemical Methods in Diabetology), - Anti-atherosclerotic activity. New chapters are added such as Auditory Pharmacology, Oncology Activity, Stem Cells, Omics, Personalized Medicine, etc.
Download or read book The Influence of a Hypercaloric Diet on Gross Body and Adipose Tissue Composition in the Rat written by S. C. Peckham and published by . This book was released on 1962 with total page 40 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Edible Oil Structuring Concepts Methods and Applications written by Ashok R. Patel and published by . This book was released on 2018 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Are Rodent Models Fit for Investigation of Human Obesity and Related Diseases written by Patrick C. Even and published by Frontiers Media SA. This book was released on 2018-02-15 with total page 161 pages. Available in PDF, EPUB and Kindle. Book excerpt: Not only developed countries, but also most developing areas of the world, have experienced a surge in obesity prevalence over recent decades. Obesity complications are now among the leading causes of premature mortality, encompassing conditions such as coronary heart disease, stroke, and type 2 diabetes. This places a heavy burden on contemporary healthcare systems. While rodent models have limitations as experimental models of human obesity-related disease, study of rats and mice either spontaneously prone - or resistant - to obesity, or genetically engineered to illuminate underlying mechanisms has yielded key information about the metabolic defects linked to obesity, and their associated diseases. This topic includes both original research studies and reviews of the use of animal studies in specific areas of obesity-related disease. Various methodological approaches are discussed, with evaluation of the extent to which use of animal models has facilitated progress, or, conversely, has proved a cul de sac in investigation of human disease mechanisms. Consideration is also given to future strategies to use such rodent models optimally to enhance comprehension and treatment of pandemic human obesity-related diseases.
Download or read book In house Validation of High Fat Diet Induced Obesity Models written by POOJA SHARMA and published by LAP Lambert Academic Publishing. This book was released on 2013 with total page 108 pages. Available in PDF, EPUB and Kindle. Book excerpt: Obesity results from a prolonged imbalance between energy intake and energy expenditure, as depending on basal metabolic rate, heat production, thermogenic effects of the diet & physical activity. Diet-induced obesity in rodents can be achieved by different regimens & approaches. Diets providing a high fat intake have been established as a "gold standard" to generate obese rodent models and have proven to initiate pathologies similar to those in humans. However, this dietary treatment is far from being standardized and its relevance has been criticized. Hence, varieties of high fat diet regimens have been introduced by providing a choice of several palatable food items of variable composition. Further male rats have been considered in developing all types of obesity models and no rationale has been provided as of this discrimination and negligence of using female rats. Another pitfall in the obesity model development is that of the choice of the strain of the rats used for the study. The basis on which strain is being chosen still remains controversial. This present study aimed at comparing & validating different diet induced obesity models utilizing different strains and gender.
Download or read book The Effects of High fat Feeding on Synaptic Function in Female Rats and Their Offspring written by Isabelle Lorraine Messa-Hamidi and published by . This book was released on 2014 with total page 87 pages. Available in PDF, EPUB and Kindle. Book excerpt: The prevalence of obesity has been increasing across the globe at an unprecedented rate, and obesity is associated with a number of diseases, including diabetes, hypertension, and certain types of cancer. In recent years, increasing evidence has shown that obesity can also cause cognitive impairment, and research is increasingly aimed at elucidating both the nature of, and the mechanisms behind, these impairments in the brain. Because the hippocampus has been shown to be particularly vulnerable to these effects, both of the studies presented in this thesis aimed to investigate the effects of high-fat diet-induced obesity on hippocampal synaptic plasticity.
Download or read book Textbook of Energy Balance Neuropeptide Hormones and Neuroendocrine Function written by Eduardo A. Nillni and published by Springer. This book was released on 2018-08-06 with total page 378 pages. Available in PDF, EPUB and Kindle. Book excerpt: This textbook presents for the first time a comprehensive body of the latest knowledge in the field of neuropeptides and their action on energy balance. It contains a detailed and comprehensive account of the specific hypothalamic peptides in regards to their roles in energy balance, food intake control and co-morbidities, to better understand the patho-physiology of obesity. The textbook includes an examination the history of the evolution of human society from a thin to the obese phenotype and, within that context, how modern society habits and industrial food production did not respect the evolutionary trait resulting in changes in the energy balance set point. It provides a novel conceptualization of the problem of obesity when considering the biochemistry of peptide hormones and entertaining novel ideas on multiple approaches to the problems of energy balance, as well as demonstrates and explains why alterations in pro-hormone processing are paramount to understand metabolic disease. This text is excellent material for teaching graduate and medical school courses, as well as a valuable resource for researchers in biochemistry, cell, and molecular biology, neuroscientists, physician endocrinologists, and nutritionists.
Download or read book Nutrient Requirements of Laboratory Animals written by National Research Council and published by National Academies Press. This book was released on 1995-02-01 with total page 188 pages. Available in PDF, EPUB and Kindle. Book excerpt: In the years since the third edition of this indispensable reference was published, a great deal has been learned about the nutritional requirements of common laboratory species: rat, mouse, guinea pig, hamster, gerbil, and vole. The Fourth Revised Edition presents the current expert understanding of the lipid, carbohydrate, protein, mineral, vitamin, and other nutritional needs of these animals. The extensive use of tables provides easy access to a wealth of comprehensive data and resource information. The volume also provides an expanded background discussion of general dietary considerations. In addition to a more user-friendly organization, new features in this edition include: A significantly expanded section on dietary requirements for rats, reporting substantial new findings. A new section on nutrients that are not required but that may produce beneficial results. New information on growth and reproductive performance among the most commonly used strains of rats and mice and on several hamster species. An expanded discussion of diet formulation and preparationâ€"including sample diets of both purified and natural ingredients. New information on mineral deficiency and toxicity, including warning signs. This authoritative resource will be important to researchers, laboratory technicians, and manufacturers of laboratory animal feed.
Download or read book Pathophysiology of Obesity Induced Health Complications written by Paramjit S. Tappia and published by Springer Nature. This book was released on 2020-01-17 with total page 348 pages. Available in PDF, EPUB and Kindle. Book excerpt: According to the World Health Organization, the epidemic of global obesity has nearly tripled since 1975. In 2016, more than 1.9 billion adults were overweight, over 650 million of which were obese. Being overweight and obese has been linked to a number of non-communicable, chronic diseases. Pathophysiology of Obesity-Induced Health Complications is a compilation of review articles dedicated to describe co-morbidities associated with obesity. The wide range that is covered is of significant interest to basic research scientists, clinicians and graduate students who are engaged in studying obesity-induced health complications. Furthermore, this book highlights the potential of novel approaches for the prevention and treatment of obesity and its related illnesses. Nineteen articles in this book are organized in four sections that are designed to provide an overview of obesity-induced health complications. The first section serves as an introductory section on the prevalence, causes, consequences, treatments and preventive approaches for obesity. Section two covers the metabolic disturbances and inflammation due to obesity. The third section is focused on neurological and visceral complications as a consequence of obesity. The final section covers strategies for the prevention of obesity-induced complications. The book illustrates that obesity can result in a diverse range of pathophysiological conditions that adversely affect health.
Download or read book Effects of Overfeeding Suckling Rats on Fat Organ Cellularity written by Barbara Estelle Obst and published by . This book was released on 1976 with total page 230 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Effect of Diet and Detraining on Adipocyte Proliferation in Rats written by Jill A. Rose-Ellis and published by . This book was released on 1988 with total page 242 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Lessons from Dietary Obesity in the Rat written by Elena Velkoska and published by LAP Lambert Academic Publishing. This book was released on 2009-11 with total page 244 pages. Available in PDF, EPUB and Kindle. Book excerpt: Obesity places an enormous burden on global health resources. The prevalence of obesity is increasing worldwide and of particular concern is the increasing incidence of obesity in children and adolescents that is frequently associated with diabetes and hypertension. Altered nutrition during critical periods of development can increase the risk of obesity, hypertension and cardiovascular disease in adulthood. This book outlines experiments using animal models of obesity, aimed at determining the interaction of early and late feeding state on subsequent obesity risk. The work examines both physiological and pharmacological interventions to assess the response of various brain peptides and adipose derived mediators involved in energy homeostasis in two different models of dietary obesity in the rat: overnourishment beginning immediately in the postnatal period and obesity induced in adulthood by consumption of palatable, high fat foods. The studies described in this book provide evidence of the importance of early postnatal nutrition and the consequences of consuming a high fat diet in adulthood.
Download or read book Obese Humans and Rats Psychology Revivals written by Stanley Schacter and published by Psychology Press. This book was released on 2014-10-14 with total page 195 pages. Available in PDF, EPUB and Kindle. Book excerpt: Originally published in 1974, this volume examines the behavioural similarities of obese humans and animals whose so-called feeding centre (the ventro-medial hypothalamic nuclei) has been lesioned. Both the obese human and the VMH-lesioned animal seem to share a hyposensitivity to the internal (physiological) cues to eating and hypersensitivity to external cues associated with food. Beginning with a review, these obese animals and the human obese are compared point by point on experimental results reported in the literature. Then, new findings are presented that specifically tested humans for relationships that are well-established for lesioned animals. Next, a theoretical framework integrates the human and animal data to postulate that the relationship of cue prominence and probability of response is stronger for the obese than for normal. The causes for this, and the extension of the basis for the obese’s eating behaviour to other areas, are discussed in light of further experiments that will make this invaluable reading for all concerned with the history of obesity and the issues of regulatory behaviour.
Download or read book Neurobehavioral Toxicity written by Bernard Weiss and published by CRC Press. This book was released on 1994-06-30 with total page 418 pages. Available in PDF, EPUB and Kindle. Book excerpt: In establishing how certain chemicals can cause behavioural disorders, the process of neurotoxicity risk assessment poses significant challenges to every discipline within neuroscience. In this volume, leaders from industrial, academic, and government settings share insights on behavioural measurement in neurotoxicity risk assessment, and address the critical scientific issues arising from the expanding role of neurobehavioral toxicology in public policy development.; The authors set out to provide a comprehensive and authoritative review of current methods in the analysis and interpretation of neurobehavioural toxicology. Coverage begins with a discussion of criteria for determining neurotoxic potential. The next section examines neurobehavioural evaluations in developmental neurotoxicity. Subsequent sections focus on activity and observational data and applications of schedule-controlled operant behaviour in toxicity testing. The contributors address controversies surrounding the suitability and interpretation of procedures designed for neurotoxicological assessments. Some case studies are also included.
