Download or read book Developing a Protocol for Observational Comparative Effectiveness Research A User s Guide written by Agency for Health Care Research and Quality (U.S.) and published by Government Printing Office. This book was released on 2013-02-21 with total page 236 pages. Available in PDF, EPUB and Kindle. Book excerpt: This User’s Guide is a resource for investigators and stakeholders who develop and review observational comparative effectiveness research protocols. It explains how to (1) identify key considerations and best practices for research design; (2) build a protocol based on these standards and best practices; and (3) judge the adequacy and completeness of a protocol. Eleven chapters cover all aspects of research design, including: developing study objectives, defining and refining study questions, addressing the heterogeneity of treatment effect, characterizing exposure, selecting a comparator, defining and measuring outcomes, and identifying optimal data sources. Checklists of guidance and key considerations for protocols are provided at the end of each chapter. The User’s Guide was created by researchers affiliated with AHRQ’s Effective Health Care Program, particularly those who participated in AHRQ’s DEcIDE (Developing Evidence to Inform Decisions About Effectiveness) program. Chapters were subject to multiple internal and external independent reviews. More more information, please consult the Agency website: www.effectivehealthcare.ahrq.gov)
Download or read book Nonlinearity Bounded Rationality and Heterogeneity written by Tamotsu Onozaki and published by Springer. This book was released on 2018-01-28 with total page 227 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book pursues a nonlinear approach in considering both chaotic dynamical models and agent-based simulation models of economics, as well as their dynamical behaviors. Three key concepts arising in this context are “nonlinearity,” “bounded rationality” and “heterogeneity,” which also make up the title of the book. Nonlinearity is the warp that runs throughout all models because systems that exhibit chaotic or other complex behavior in the absence of any exogenous disturbances are absolutely nonlinear. Bounded rationality constitutes the woof, because economic systems do not exhibit complex behavior if all agents are perfectly rational, as is usually assumed in neoclassical economics. Agents who are boundedly rational have to struggle to do their best with limited information and tend to adapt to their economic environment without knowing what is the best. Furthermore, the heterogeneity of firms or consumers dyes the fabric of complex dynamics woven from the warp and woof.
Download or read book Ecological Heterogeneity written by Jurek Kolasa and published by New York : Springer-Verlag. This book was released on 1991 with total page 352 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Doing Meta Analysis with R written by Mathias Harrer and published by CRC Press. This book was released on 2021-09-15 with total page 500 pages. Available in PDF, EPUB and Kindle. Book excerpt: Doing Meta-Analysis with R: A Hands-On Guide serves as an accessible introduction on how meta-analyses can be conducted in R. Essential steps for meta-analysis are covered, including calculation and pooling of outcome measures, forest plots, heterogeneity diagnostics, subgroup analyses, meta-regression, methods to control for publication bias, risk of bias assessments and plotting tools. Advanced but highly relevant topics such as network meta-analysis, multi-three-level meta-analyses, Bayesian meta-analysis approaches and SEM meta-analysis are also covered. A companion R package, dmetar, is introduced at the beginning of the guide. It contains data sets and several helper functions for the meta and metafor package used in the guide. The programming and statistical background covered in the book are kept at a non-expert level, making the book widely accessible. Features • Contains two introductory chapters on how to set up an R environment and do basic imports/manipulations of meta-analysis data, including exercises • Describes statistical concepts clearly and concisely before applying them in R • Includes step-by-step guidance through the coding required to perform meta-analyses, and a companion R package for the book
Download or read book Theory of Sampling and Sampling Practice Third Edition written by Francis F. Pitard and published by CRC Press. This book was released on 2019-01-10 with total page 694 pages. Available in PDF, EPUB and Kindle. Book excerpt: A step-by-step guide for anyone challenged by the many subtleties of sampling particulate materials. The only comprehensive document merging the famous works of P. Gy, I. Visman, and C.O. Ingamells into a single theory in a logical way - the most advanced book on sampling that can be used by all sampling practitioners around the world.
Download or read book Introduction to Quantitative Macroeconomics Using Julia written by Petre Caraiani and published by Academic Press. This book was released on 2018-08-29 with total page 240 pages. Available in PDF, EPUB and Kindle. Book excerpt: Introduction to Quantitative Macroeconomics Using Julia: From Basic to State-of-the-Art Computational Techniques facilitates access to fundamental techniques in computational and quantitative macroeconomics. It focuses on the recent and very promising software, Julia, which offers a MATLAB-like language at speeds comparable to C/Fortran, also discussing modeling challenges that make quantitative macroeconomics dynamic, a key feature that few books on the topic include for macroeconomists who need the basic tools to build, solve and simulate macroeconomic models. This book neatly fills the gap between intermediate macroeconomic books and modern DSGE models used in research. - Combines an introduction to Julia, with the specific needs of macroeconomic students who are interested in DSGE models and PhD students and researchers interested in building DSGE models - Teaches fundamental techniques in quantitative macroeconomics by introducing theoretical elements of key macroeconomic models and their potential algorithmic implementations - Exposes researchers working in macroeconomics to state-of-the-art computational techniques for simulating and solving DSGE models
Download or read book Membrane active Peptides written by Miguel A. R. B. Castanho and published by Internat'l University Line. This book was released on 2010 with total page 675 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Novel Therapeutic Strategies for Chronic HBV Infection An Immunological Perspective written by Seung Kew Yoon and published by Frontiers Media SA. This book was released on 2020-08-14 with total page 144 pages. Available in PDF, EPUB and Kindle. Book excerpt: Chronic hepatitis B (CHB) is a life-threatening liver disease affecting 257 million people worldwide, in particular in the Asia-Pacific regions. In endemic areas, hepatitis B virus (HBV) is usually transmitted from chronically infected mothers to neonates. Perinatal HBV infection causes chronic infection in more than 90% of exposed individuals. With perinatal infection, lifetime mortality risk due to complications of liver cirrhosis (LC) or hepatocellular carcinoma (HCC) reaches up to 40% in men and 15% in women. For the treatment of chronic HBV infection, nucleos(t)ide analogue antivirals have been successfully used to suppress viral replication. However, HBV exists as a cccDNA, which cannot be eliminated by nucleos(t)ide analogues. Therefore, a practical goal of novel HBV therapeutics can be HBs seroconversion (loss of HBsAg and development of HBsAg-specific antibodies), which occurs during spontaneous recovery from acute HBV infection. This HBs seroconversion is referred to as “functional cure” of HBV infection. When functional cure is reached, HBsAg-specific antibodies have virus-neutralizing activity and control HBV infection even in the presence of cccDNA. Currently, peg-IFN-a is often used to induce HBs seroconversion in patients with chronic HBV infection; however, the efficacy is not satisfactory. In future, other immunological therapeutics must be considered to achieve HBs seroconversion, including therapeutic vaccines and immune checkpoint blockers.
Download or read book Testing the Proportional Hazards Assumption in the Presence of Unmeasured Heterogeneity written by Brian Patrick McCall and published by . This book was released on 1992 with total page 60 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Geology and Geomorphology of Alluvial and Fluvial Fans written by D. Ventra and published by Geological Society of London. This book was released on 2018-07-04 with total page 351 pages. Available in PDF, EPUB and Kindle. Book excerpt: Alluvial and fluvial fans are the most widespread depositional landform bordering the margins of highland regions and actively subsiding continental basins, across a broad spectrum of tectonic and climatic settings. They are significant to the local morphodynamics of mountain regions and also to the evolution of sediment-routing systems, affecting the propagation and preservation of stratigraphic signals of environmental change over vast areas. The volume presents case studies discussing the geology and geomorphology of alluvial and fluvial fans from both active systems and ancient ones preserved in the stratigraphic record. It brings together case studies from a range of continents, climatic and tectonic settings, some introducing innovative monitoring and analysis techniques, and it provides an overview of current debates in the field. This volume will be of particular interest to geologists, geomorphologists, sedimentologists and the general reader with an interest in Earth science.
Download or read book SME Mineral Processing and Extractive Metallurgy Handbook written by Courtney A. Young and published by Society for Mining, Metallurgy & Exploration. This book was released on 2019-02-01 with total page 2258 pages. Available in PDF, EPUB and Kindle. Book excerpt: This landmark publication distills the body of knowledge that characterizes mineral processing and extractive metallurgy as disciplinary fields. It will inspire and inform current and future generations of minerals and metallurgy professionals. Mineral processing and extractive metallurgy are atypical disciplines, requiring a combination of knowledge, experience, and art. Investing in this trove of valuable information is a must for all those involved in the industry—students, engineers, mill managers, and operators. More than 192 internationally recognized experts have contributed to the handbook’s 128 thought-provoking chapters that examine nearly every aspect of mineral processing and extractive metallurgy. This inclusive reference addresses the magnitude of traditional industry topics and also addresses the new technologies and important cultural and social issues that are important today. Contents Mineral Characterization and AnalysisManagement and ReportingComminutionClassification and WashingTransport and StoragePhysical SeparationsFlotationSolid and Liquid SeparationDisposalHydrometallurgyPyrometallurgyProcessing of Selected Metals, Minerals, and Materials
Download or read book Heterogeneous Computing Architectures written by Olivier Terzo and published by CRC Press. This book was released on 2019-09-10 with total page 316 pages. Available in PDF, EPUB and Kindle. Book excerpt: Heterogeneous Computing Architectures: Challenges and Vision provides an updated vision of the state-of-the-art of heterogeneous computing systems, covering all the aspects related to their design: from the architecture and programming models to hardware/software integration and orchestration to real-time and security requirements. The transitions from multicore processors, GPU computing, and Cloud computing are not separate trends, but aspects of a single trend-mainstream; computers from desktop to smartphones are being permanently transformed into heterogeneous supercomputer clusters. The reader will get an organic perspective of modern heterogeneous systems and their future evolution.
Download or read book Heterogeneity and Output Fluctuations in a Dynamic Menu cost Economy written by Ricardo J. Caballero and published by . This book was released on 1991 with total page 56 pages. Available in PDF, EPUB and Kindle. Book excerpt: When firms face menu costs, the relation between their output and money is highly nonlinear. At the aggregate level, however, this needs not be so. In this paper we study the dynamic behavior of a general equilibrium menu-cost economy where firms are heterogeneous in the shocks they perceive, and the demands and adjustment Costs they face. In this context we (i) generalize the Caplin and Spulber [1987] steady state monetary neutrality result; (ii) show that uniqueness of equilibria depends not only on the degree of strategic complementarities but also on the degree of dispersion of firms' positions in their price-cycle; (iii) characterize the path of output outside the steady state and show that as strategic complementarities become more important, expansions become longer and smoother than contractions; and (iv) show that the potential effectiveness of monetary policy is an increasing function of the distance of the economy from its steady state, but that an uninformed policy maker will have no effect on output on average.
Download or read book Parallel Computing on Heterogeneous Networks written by Alexey L. Lastovetsky and published by John Wiley & Sons. This book was released on 2008-05-02 with total page 440 pages. Available in PDF, EPUB and Kindle. Book excerpt: New approaches to parallel computing are being developed that make better use of the heterogeneous cluster architecture Provides a detailed introduction to parallel computing on heterogenous clusters All concepts and algorithms are illustrated with working programs that can be compiled and executed on any cluster The algorithms discussed have practical applications in a range of real-life parallel computing problems, such as the N-body problem, portfolio management, and the modeling of oil extraction
Download or read book Heterogeneous Information Network Analysis and Applications written by Chuan Shi and published by Springer. This book was released on 2017-05-25 with total page 233 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book offers researchers an understanding of the fundamental issues and a good starting point to work on this rapidly expanding field. It provides a comprehensive survey of current developments of heterogeneous information network. It also presents the newest research in applications of heterogeneous information networks to similarity search, ranking, clustering, recommendation. This information will help researchers to understand how to analyze networked data with heterogeneous information networks. Common data mining tasks are explored, including similarity search, ranking, and recommendation. The book illustrates some prototypes which analyze networked data. Professionals and academics working in data analytics, networks, machine learning, and data mining will find this content valuable. It is also suitable for advanced-level students in computer science who are interested in networking or pattern recognition.
Download or read book Research Frontiers in Aging and Cancer written by and published by . This book was released on 1982 with total page 324 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Principles of Econometrics written by R. Carter Hill and published by John Wiley & Sons. This book was released on 2018-02-21 with total page 1808 pages. Available in PDF, EPUB and Kindle. Book excerpt: Principles of Econometrics, Fifth Edition, is an introductory book for undergraduate students in economics and finance, as well as first-year graduate students in a variety of fields that include economics, finance, accounting, marketing, public policy, sociology, law, and political science. Students will gain a working knowledge of basic econometrics so they can apply modeling, estimation, inference, and forecasting techniques when working with real-world economic problems. Readers will also gain an understanding of econometrics that allows them to critically evaluate the results of others’ economic research and modeling, and that will serve as a foundation for further study of the field. This new edition of the highly-regarded econometrics text includes major revisions that both reorganize the content and present students with plentiful opportunities to practice what they have read in the form of chapter-end exercises.
