Download or read book Gastrointestinal and Hepatic Immunology written by Richard Heatley and published by Cambridge University Press. This book was released on 1994-10-27 with total page 412 pages. Available in PDF, EPUB and Kindle. Book excerpt: This 1994 volume summarizes basic scientific advances in the area of the gut immune system and the immune abnormalities relevant to gastrointestinal and liver disease.
Download or read book Immunological Aspects of the Liver and Gastrointestinal Tract written by A. Ferguson and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 413 pages. Available in PDF, EPUB and Kindle. Book excerpt: We have been privileged to start our academic careers at the begin ning of the decade in which the immunological roles and hypersensitivity diseases of the gastrointestinal tract and liver have been defined. In the early 1960s IgA was reported to be the main secretory immunoglobulin, immunoblasts were shown to home to the intestinal mucosa and certain serum autoantibodies were described in patients with chronic liver disease. Shortly thereafter IgE and Australia antigen were discovered. Parallel advances in clinical investigation, in particular closed biopsy techniques, facilitated correlation of morphological changes with im munological mechanisms in disease of the gastrointestinal tract and liver. Only 10 years later, the concepts of immunity and hypersensitivity are regularly applied to the pathogenesis, diagnosis, treatment and prog nosis of many chronic diseases in these organs. In designing this book we have attempted to integrate theorectical and clinical immunology as they pertain in 1975; our ultimate aim is aptly described by Brachet as quoted by Professor Paronetto (page 319). We would like to think that this review provides a basis for the next major advances in the fields of gastrointestinal and hepatic immunology. As we see it, the outstanding problem in both sites is how to produce protective immunity without hypersensitivity.
Download or read book Immunology of the Gastrointestinal Tract and Liver written by Martin F. Heyworth and published by Lippincott Williams & Wilkins. This book was released on 1988 with total page 250 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Clinical Immunology of the Liver and Gastrointestinal Tract written by David R. Triger and published by Butterworth-Heinemann. This book was released on 1986 with total page 260 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Immunology and Immunopathology of the Liver and Gastrointestinal Tract written by Stephan R. Targan and published by Igaku-Shoin Medical Publishers. This book was released on 1990 with total page 680 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Immunology of Gastrointestinal and Liver Disease written by Ralph Wright (M.D.) and published by Hodder Education. This book was released on 1977 with total page 148 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Immunological Diseases of Liver and Gut written by M. Lukás and published by Springer Science & Business Media. This book was released on 2004-06-30 with total page 338 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book is the proceedings of the Falk Symposium No. 135 held in Prague, Czech Republic, on September 12-13, 2003, and is dedicated to the important issue of immunological aspects of diseases of the liver and gut. Without any doubt, immunological pathways are among the most important and universal factors in the pathogenesis of all diseases. Their importance is also constantly increasing, because these principles have been adopted in clinical practice for both diagnostic and therapeutic procedures. Chapters by prominent experts will stimulate new ideas and set the scene for productive discussion on this topic.
Download or read book Gut and the Liver written by H.E. Blum and published by Springer Science & Business Media. This book was released on 1998-02-28 with total page 450 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book, the proceedings of Falk Symposium 100, `Gut and the Liver', held in Freiburg, Germany, 29-31 May 1997, comprehensively reviews the physiological and pathophysiological interactions between the intestine and the liver as well as between intestinal and hepatic diseases. Apart from the basic aspects of the intestinal microflora and the immune system of the gut, gastrointestinal permeability and translocation as well as the contribution of the intestine and the intestinal bacteria to the metabolism of bile acids, amino acids and drugs are discussed. In addition, experimental as well as clinical data demonstrating the significance of gut-derived bacterial toxins for the development of liver diseases and the effect of liver diseases on gastrointestinal functions are discussed. The major aim of this book, therefore, is to highlight the interactions between gut and liver at the molecular level as well as in clinical disease.
Download or read book Gastrointestinal and Liver Immunology written by Ralph Wright and published by . This book was released on 1987 with total page 254 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Liver Immunology written by M. Eric Gershwin and published by Springer Science & Business Media. This book was released on 2013-11-19 with total page 482 pages. Available in PDF, EPUB and Kindle. Book excerpt: Liver Immunology: Principles and Practice, Second Edition begins with important information about the epidemiology and mortality of liver disease worldwide. This information is followed by chapters related to basic immunology, application of liver immunology for diagnosis, and several excellent chapters that provide a solid foundation for understanding immune-mediated liver disease, including those associated with the biliary tree. A chapter on non-hepatic manifestations of immune mediated liver disease helps provide context for how these diseases affect the patient overall. In addition, chapters discuss various discrete immunologically-mediated infectious liver disorders including those related to bacteria, parasites, and all of the classic viruses. Chapters on the traditional autoimmune liver diseases -- primary biliary cirrhosis, autoimmune hepatitis, primary sclerosing cholangitis as well as overlap syndrome – are also included. The breadth of this comprehensive second edition is highlighted by chapters on alcoholic liver disease, non-alcoholic fatty liver disease, and drug-induced liver disease, among others. This invaluable new edition ends with a forward-looking view of future directions and how the field might meet the challenge of refractory patients. Developed by a renowned group of authors, Liver Immunology: Principles and Practice, Second Edition will again serve as a comprehensive textbook by providing an excellent overview for this rapidly evolving field. It greatly adds to the understanding of the pathogenesis of these diseases, while also providing novel insights that can be harnessed into helping improve the care of patients afflicted with various immune-mediated diseases. This volume will again be a must-read for clinicians at all levels, investigators and students.
Download or read book Hepatic Immunology and Gastrointestinal written by Claire Mackay and published by . This book was released on 2019 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Liver Immunology written by M. Eric Gershwin and published by Springer Nature. This book was released on 2020-11-03 with total page 631 pages. Available in PDF, EPUB and Kindle. Book excerpt: The third edition of this acclaimed work provides clinicians and investigators with a wealth of state-of-the-art information that will lead to fresh approaches in thinking about liver physiology and liver diseases. Developed by a panel of renowned international authors, this edition outlines a range of important advances in our understanding of the liver’s role as an immune organ and the functions of innate and adaptive immunity in the pathogenesis of all liver diseases. Indeed, the liver is a vitally important immune organ producing liver-derived products that can trigger the innate and adaptive immune system to initiate, mediate, regulate, and resolve systemic inflammation. The book begins with an analysis of the core concepts of immunology, including the definition of autoimmunity and its unique application to the liver, a tolerogenic organ. Subsequent chapters then explore the biological elements of liver diseases caused by epigenetics, genetics, and innate and adaptive immunity. Specific clinical presentations and aspects of liver diseases are also examined, such as Hepatitis C, non-alcoholic fatty liver disease and parasitic infections. Closing chapters then discuss liver diseases among specific populations, including pediatrics, those with comorbidities and preexisting conditions, pregnant women, and finally patients with transplanted organs. A timely and invaluable update to the clinical literature, Liver Immunology: Principles and Practice, Third Edition, is once again a comprehensive work that will not only enhance the understanding of liver diseases but also provide the kind of novel insights that greatly accelerates the evidence-based care of children and adults afflicted with these diseases. This volume is again a must-read for clinicians at all levels, for investigators and for students.
Download or read book The Undergraduate Teaching Project in Gastroenterology and Liver Disease written by American Gastroenterological Association. Undergraduate Teaching Project in Gastroenterology and Liver Disease and published by . This book was released on 1984 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Clinical Update on Inflammatory Disorders of the Gastrointestinal Tract written by Julia Mayerle and published by Karger Medical and Scientific Publishers. This book was released on 2010 with total page 225 pages. Available in PDF, EPUB and Kindle. Book excerpt: Digestive-disease-associated mortality accounts for a major part of all deaths in Western societies and inflammatory diseases such as GI infections, viral hepatitis, GERD or cancers due to chronic inflammation have a tangible economic and social impact. What further aggravates the situation is the fact that complex immunological disorders have surfaced where anti-infective treatments are not effective. Fortunately, due to breakthroughs in basic research that are being successfully translated into clinical practice, new treatment strategies are constantly evolving. In addition to the development of new therapeutic measures, however, it is also mandatory to review and periodically refine established treatment regimens to reflect current knowledge and ensure up-to-date medical care.Combining outstanding basic research reviews with cutting-edge treatment guidelines on inflammatory disorders of the GI tract, this book presents newly identified treatment targets and provides clinicians and practitioners in the field with a most useful account of the state of the art.
Download or read book Neuro Immuno Gastroenterology written by Cris S. Constantinescu and published by Springer. This book was released on 2016-05-24 with total page 345 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book addresses important issues regarding the interaction between the nervous system, the immune system, and the digestive system. Gut flora has a profound influence on the shaping of the immune response, not only in the gastrointestinal system but also in the nervous system. Fascinatingly, manipulation of intestinal immune responses can be used to modulate neurological disease. Conversely, the nervous system and the psyche have significant effects on the functioning of the gut and liver. After introductory chapters on the neurology, the immunology and microbiology of the gut, the effects of the gut immune system and gut flora and its manipulation on neurological disease are discussed, followed by molecular mimicry and immune tolerance in neuroimmune diseases. Additionally, several chapters deal with gastrointestinal manifestations of neurological diseases. Neuro-Immuno-Gastroenterology is aimed at neurologists, gastroenterologists, and immunologists.
Download or read book Gastrointestinal Immunity for the Clinician written by Roy Gerrard Shorter and published by Saunders. This book was released on 1985 with total page 296 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Autoimmune Diseases in Pediatric Gastroenterology written by Faruk Hadziselimovic and published by Springer Science & Business Media. This book was released on 2002-09-30 with total page 304 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book is the proceedings of the Falk Symposium No. 127 on `Autoimmune Diseases in Paediatric Gastroenterology' (IV International Falk Symposium on Paediatric Gastroenterology), held in Basel, Switzerland, on November 8-9, 2001. The symposium focused on the role of the immune system, both the acquired and the innate systems, in inflammatory bowel disease (IBD) in children and adolescents. The innate system has an important fundamental role in host defence by initiating immune responses against potentially deleterious matter. However, a mutation within the innate system may elicit an immune response against the host: hence, an autoimmune response. Chronic autoimmune hepatitis occurs predominantly in young people, and especially in women. Immunological changes are conspicuous. Tissue antibodies are found in a large number of patients. This is a disease of disordered immunoregulation marked by a deficit in suppressor T cells causing the production of autoantibodies against specific hepatocyte surface antigen. Liver membrane protein is found in the sera of patients with autoimmune chronic acute hepatitis and with primary biliary cirrhosis (PBC). The latter condition of progressive granulomatous destruction of intrahepatic bile ducts is, in many respects, analogous to the graft-versus-host syndrome where the immune system has become sensitized to foreign HLA-molecules. Primary sclerosing cholangitis (PSC) is another condition of unknown origin. All parts of the biliary tree can be involved in a chronic, fibrosing, inflammatory process that results in obliteration of the biliary tree and ultimately in biliary cirrhosis. About half of the patients also suffer from ulcerative colitis and rarely from Crohn's disease. Circulating antibodies to some antigens are found in obstructed portal tracts, as well as increased concentrations of biliary immune complexes in patients with PBC. In all three previous Falk symposia on paediatric gastroenterology, attention was focused on the role of the innate immune system in the aetiology of IBD. It has become increasingly clear in recent years that the innate system has a much more important and fundamental role in host defence. The decision to initiate an immune response is one of the major roles of the innate system. Mutations within this system could transform it into becoming constitutively active, resulting in an inflammatory reaction and thus eliciting an autoimmune response. Following an introduction to the basic phenomena of autoimmunity, the proceedings discuss clinical aspects of autoimmune diseases. In particular, current knowledge and the state of the art about the diagnosis and treatment of the autoimmune diseases of the gastrointestinal tract are described by world-renowned experts. The book also contains the short presentations on selected topics, as well as abstracts of the mini-posters read by title, which were included in the symposium.
