Download or read book Handbook of Synthetic Substrates written by H.C. Hemker and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 182 pages. Available in PDF, EPUB and Kindle. Book excerpt: The need for a handbook on the use of synthetic substrates for assay of proteases of the coagulation and fibrinolytic systems became evident several years ago during the activities of the Subcommittee on Synthetic Substrates of the International Committee on Thrombosis and Haemo stasis (lCTH). Production of such a handbook, which was recommended during discussions of the ICTH at its meeting in London in 1979 was made possible by the generous efforts of Professor HC Hemker with the aid of several contributors with particular interests in the use of synthetic substrates in coagulation and fibrinolysis. As current Chairman and Secretary General of the ICTH we would like to express our sincere thanks to Professor Hemker for producing this handbook and look for ward to seeing the benefits of this tremendous effort reflected in the advancement of our understanding of thrombosis and hemostasis and the transfer of such knowledge into improved diagnosis and treatment of thrombotic and hemorrhagic disorders. Craig M Jackson Professor of Biological Chemistry Washington University School of Medicine, St. Louis, MO Chairman, ICTH Harold R Roberts Professor of Internal Medicine University of North Carolina, Chapel Hill, NC Secretary General, ICTH ix Foreword The advent of synthetic substrates for the study of blood coagulation and fibrinolysis was a significant step forward in the investigation of these systems. Both basic research and clinical laboratory investigations can profit from these advanced tools.
Download or read book Modern Inorganic Synthetic Chemistry written by Ruren Xu and published by Elsevier. This book was released on 2011-01-13 with total page 612 pages. Available in PDF, EPUB and Kindle. Book excerpt: The contributors to this book discuss inorganic synthesis reactions, dealing with inorganic synthesis and preparative chemistry under specific conditions. They go on to describe the synthesis, preparation and assembly of six important categories of compounds with wide coverage of distinct synthetic chemistry systems
Download or read book Practical Synthetic Organic Chemistry written by Stéphane Caron and published by John Wiley & Sons. This book was released on 2011-07-26 with total page 870 pages. Available in PDF, EPUB and Kindle. Book excerpt: A hands-on guide to assist in the planning and execution of synthetic reactions in the laboratory Despite the maturity of organic chemistry, it can still be very challenging to identify optimal methods for synthetic transformations that perform as well in real-world manufacturing processes as they do in the laboratory. This detailed and accessible guide attempts to address this vexing issue and deliver proven methodologies practicing synthetic chemists will find valuable for identifying reaction conditions that work reliably over the broadest possible range of substrates. Practical Synthetic Organic Chemistry: Provides a practical guide to strategically planning and executing chemical syntheses for the bench chemist in industry Discusses information that is not common knowledge beyond the boundaries of process chemistry groups, such as the synthetic routes of selected contemporary pharmaceutical drugs and practical solvents, as well as green chemistry concepts Highlights key reactions, including substitutions, additions, eliminations, rearrangements, oxidations, and reductions Addresses basic principles, mechanisms, advantages and disadvantages of the methodology, and techniques for achieving laboratory success Incorporating such an extraordinary wealth of information on organic chemistry and its related fields into one complete volume distinguishes Practical Synthetic Organic Chemistry as an incomparable desktop reference for professionals and an invaluable study aid for students.
Download or read book Handbook of Food Analytical Chemistry Volume 1 written by Ronald E. Wrolstad and published by John Wiley & Sons. This book was released on 2005-09-02 with total page 1397 pages. Available in PDF, EPUB and Kindle. Book excerpt: Emphasizing effective, state-of-the art methodology and written by recognized experts in the field, the Handbook of Food Analytical Chemistry is an indispensable reference for food scientists and technologists to enable successful analysis. * Provides detailed reports on experimental procedures * Includes sections on background theory and troubleshooting * Emphasizes effective, state-of-the art methodology, written by recognized experts in the field * Includes detailed instructions with annotated advisory comments, key references with annotation, time considerations and anticipated results
Download or read book Handbook of Immunological Properties of Engineered Nanomaterials written by Marina Dobrovolskaia and published by World Scientific. This book was released on 2013 with total page 721 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Handbook of Immunological Properties of Engineered Nanomaterials provides a comprehensive overview of the current literature, methodologies, and translational and regulatory considerations in the field of nanoimmunotoxicology. The main subject is the immunological properties of engineered nanomaterials. Focus areas include interactions between engineered nanomaterials and red blood cells, platelets, endothelial cells, professional phagocytes, T cells, B cells, dendritic cells, complement and coagulation systems, and plasma proteins, with discussions on nanoparticle sterility and sterilization. Each chapter presents a broad literature review of the given focus area, describes protocols and resources available to support research in the individual focus areas, highlights challenges, and outlines unanswered questions and future directions. In addition, the Handbook includes an overview of and serves a guide to the physicochemical characterization of engineered nanomaterials essential to conducting meaningful immunological studies of nanoparticles. Regulations related to immunotoxicity testing of materials prior to their translation into the clinic are also reviewed.The Handbook is written by top experts in the field of nanomedicine, nanotechnology, and translational bionanotechnology, representing academia, government, industry, and consulting organizations, and regulatory agencies. The Handbook is designed to serve as a textbook for students, a practical guide for research laboratories, and an informational resource for scientific consultants, reviewers, and policy makers. It is written such that both experts and beginners will find the information highly useful and applicable.
Download or read book Microstrip Antenna Design Handbook written by Ramesh Garg and published by Artech House. This book was released on 2001 with total page 878 pages. Available in PDF, EPUB and Kindle. Book excerpt: Based on Bahl and Bhartia's popular 1980 classic, Microstrip Antennas, this all new book provides the detail antenna engineers and designers need to design any type of microstrip antenna. After addressing essential microchip antenna theory, the authors highlight current design and engineering practices, emphasizing the most pressing issues in this area, including broadbanding, circular polarization, and active microstrip antennas in particular. Special design challenges, ranging from dual polarization, high bandwidth, and surface wave mitigation, to choosing the proper substrate, and shaping an antenna to achieve desired results are all covered.
Download or read book PEEK Biomaterials Handbook written by Steven M. Kurtz and published by William Andrew. This book was released on 2011-11-09 with total page 309 pages. Available in PDF, EPUB and Kindle. Book excerpt: PEEK biomaterials are currently used in thousands of spinal fusion patients around the world every year. Durability, biocompatibility and excellent resistance to aggressive sterilization procedures make PEEK a polymer of choice, replacing metal in orthopedic implants, from spinal implants and hip replacements to finger joints and dental implants. This Handbook brings together experts in many different facets related to PEEK clinical performance as well as in the areas of materials science, tribology, and biology to provide a complete reference for specialists in the field of plastics, biomaterials, medical device design and surgical applications. Steven Kurtz, author of the well respected UHMWPE Biomaterials Handbook and Director of the Implant Research Center at Drexel University, has developed a one-stop reference covering the processing and blending of PEEK, its properties and biotribology, and the expanding range of medical implants using PEEK: spinal implants, hip and knee replacement, etc. Covering materials science, tribology and applications Provides a complete reference for specialists in the field of plastics, biomaterials, biomedical engineering and medical device design and surgical applications
Download or read book Handbook of Culture Media for Food and Water Microbiology written by Janet E. L. Corry and published by Royal Society of Chemistry. This book was released on 2012 with total page 1036 pages. Available in PDF, EPUB and Kindle. Book excerpt: A reference for microbiologists wanting to know which media to use for the detection of various microbes in foods and how to check their performance.
Download or read book Handbook of Proteolytic Enzymes written by Alan J. Barrett and published by Academic Press. This book was released on 2012-10-30 with total page 4097 pages. Available in PDF, EPUB and Kindle. Book excerpt: Extensively revised and updated, the new edition of the highly regarded Handbook of Proteolytic Enzymes is an essential reference for biochemists, biotechnologists and molecular biologists. Edited by world-renowned experts in the field, this comprehensive work provides detailed information on all known proteolytic enzymes to date. This two-volume set unveils new developments on proteolytic enzymes which are being investigatedin pharmaceutical research for such diseases as HIV, Hepatitis C, and the common cold. Volume I covers aspartic and metallo petidases while Volume II examines peptidases of cysteine, serine, threonine and unknown catalytic type. A CD-ROM accompanies the book containing fully searchable text, specialised scissile bond searches, 3-D color structures and much more. - The only comprehensive book on proteolytic enzymes - Includes 671 chapters, each written by experts in their field, on proteolytic enzymes from all groups of living organisms and the viruses, including those that are currently major targets of pharmaceutical research - Accompanying CD-ROM provides fully searchable text, 2D structures of peptidases in color and links directly to PubMed and MEROPS databases - Each chapter describes in detail the enzyme name, its history, activity and specificity, structural chemistry, preparation, biological aspects and distinguishing features - Over 1000 peptidases included
Download or read book Bioconjugate Techniques written by Greg T. Hermanson and published by Academic Press. This book was released on 2010-07-26 with total page 1233 pages. Available in PDF, EPUB and Kindle. Book excerpt: Bioconjugate Techniques, 2nd Edition, is the essential guide to the modification and cross linking of biomolecules for use in research, diagnostics, and therapeutics. It provides highly detailed information on the chemistry, reagent systems, and practical applications for creating labeled or conjugate molecules. It also describes dozens of reactions with details on hundreds of commercially available reagents and the use of these reagents for modifying or cross linking peptides and proteins, sugars and polysaccharides, nucleic acids and oligonucleotides, lipids, and synthetic polymers. A one-stop source for proven methods and protocols for synthesizing bioconjugates in the lab Step-by-step presentation makes the book an ideal source for researchers who are less familiar with the synthesis of bioconjugates More than 600 figures that visually describe the complex reactions associated with the synthesis of bioconjugates Includes entirely new chapters on the latest areas in the field of bioconjugation as follows: Microparticles and nanoparticlesSilane coupling agentsDendrimers and dendronsChemoselective ligationQuantum dotsLanthanide chelatesCyanine dyesDiscrete PEG compoundsBuckyballs,fullerenes, and carbon nanotubesMass tags and isotope tagsBioconjugation in the study of protein interactions
Download or read book Mastering Biochemistry A Comprehensive Guide to Excellence written by Dominic Front and published by Richards Education. This book was released on with total page 217 pages. Available in PDF, EPUB and Kindle. Book excerpt: Embark on a captivating journey through the intricate realm of biochemistry with 'Mastering Biochemistry: A Comprehensive Guide to Excellence.' From the very basics to the forefront of scientific discovery, this book offers an unparalleled exploration of the building blocks of life and the molecular processes that govern it. Delve into the fascinating world of biomolecules, cellular structures, and metabolic pathways as you unravel the mysteries of DNA, enzymes, and genetic expression. With each turn of the page, gain a deeper understanding of the fundamental principles that underpin biological systems and their relevance in modern science. From the elucidation of biochemical pathways to the exploration of cutting-edge technologies like CRISPR-Cas9 and systems biology, this book equips you with the knowledge and tools to navigate the complexities of biochemistry with confidence. Whether you're a student, researcher, or simply curious about the wonders of life at the molecular level, 'Mastering Biochemistry' is your definitive guide to unlocking the secrets of the biochemical universe. Discover the excitement of scientific inquiry, the thrill of discovery, and the limitless potential of biochemistry to shape the future of medicine, biotechnology, and beyond.
Download or read book Adhesives Technology Handbook written by Sina Ebnesajjad and published by William Andrew. This book was released on 2014-11-26 with total page 437 pages. Available in PDF, EPUB and Kindle. Book excerpt: Covering a wide range of industrial applications across sectors including medical applications, automotive/aerospace, packaging, electronics, and consumer goods, this book provides a complete guide to the selection of adhesives, methods of use, industrial applications, and the fundamentals of adhesion. Dr Ebnesajjad examines the selection of adhesives and adhesion methods and challenges for all major groups of substrate including plastics (thermosets and thermoplastics), elastomers, metals, ceramics and composite materials. His practical guidance covers joint design and durability, application methods, test methods and troubleshooting techniques. The science and technology of adhesion, and the principles of adhesive bonding are explained in a way that enhances the reader's understanding of the fundamentals that underpin the successful use and design of adhesives. The third edition has been updated throughout to include recent developments in the industry, with new sections covering technological advances such as nanotechnology, micro adhesion systems, and the replacement of toxic chromate technology. Provides practitioners of adhesion technology with a complete guide to bonding materials successfully Covers the whole range of commonly used substrates including plastics, metals, elastomers and ceramics, explaining basic principles and describing common materials and application techniques Introduces the range of commercially available adhesives and the selection process alongside the science and technology of adhesion
Download or read book Cell Instructive Materials to Control and Guide Cell Function written by Paolo Netti and published by Woodhead Publishing. This book was released on 2020-11-25 with total page 260 pages. Available in PDF, EPUB and Kindle. Book excerpt: Cell Instructive Materials to Control and Guide Cell Function: Programmable Bioactive Interfaces looks at the key determinants of the dynamic interface between cell and materials and how this can be applied in developing new, bioactive biomaterials surfaces. The interface between cell and synthetic materials has attracted considerable scientific and technological interest, leading to the awareness that functional interfaces can actively guide and control specific adhesion and recognitions events. - Introduces readers to the fundamentals of complex cell-material interface dynamics - Provides valuable tools for the control of the interfacial dynamics to instruct and control cells or tissues functions - Covers the prospect of encoding specific cell instructions on, or within, a biomaterial by micro- and nano-patterning materials features
Download or read book Laboratory Guide to Enzymology written by Geoffrey A. Holdgate and published by John Wiley & Sons. This book was released on 2024-03-05 with total page 309 pages. Available in PDF, EPUB and Kindle. Book excerpt: LABORATORY GUIDE TO ENZYMOLOGY An accessible guide to understanding the foundations of enzymology at its application in drug discovery Enzymes are highly specialized proteins necessary for performing specific biochemical reactions essential for life in all organisms. In disease, the functioning of these enzymes can become altered and, therefore, enzymes represent a large class of key targets for drug discovery. In order to successfully target dysfunctional enzymes pharmaceutically, the unique mechanism of each enzyme must be understood through thorough and in-depth kinetic analysis. The topic of enzymology can appear challenging due its interdisciplinary nature combining concepts from biology, chemistry, and mathematics. Laboratory Guide to Enzymology brings together the theory of enzymology and associated lab-based work to offer a practical, accessible guide encompassing all three scientific disciplines. Beginning with a brief introduction to proteins and enzymes, the book slowly immerses the reader into the foundations of enzymology and how it can be used in drug discovery using modern methods of experimentation. The result is a detailed but highly readable volume detailing the basis of drug discovery research. Laboratory Guide to Enzymology readers will also find: Descriptions of key concepts in enzymology Examples of drugs targeting different enzymes via different mechanisms Detailed discussion about many areas of enzymology such as binding and steady-state kinetics, assay development, and enzyme inhibition and activation Laboratory Guide to Enzymology is ideal for all pharmaceutical and biomedical researchers working in enzymology and assay development, as well as advanced students in the biochemical or biomedical sciences looking to develop a working knowledge of this field of research.
Download or read book Organic Synthesis Using Samarium Diiodide written by David J. Procter and published by Royal Society of Chemistry. This book was released on 2010 with total page 221 pages. Available in PDF, EPUB and Kindle. Book excerpt: Samarium diiodide is one of the most important reducing agents available to synthetic organic chemists. The lanthanide(II) reagent acts by single-electron transfer to organic substrates leading to the formation of both radical and/or anionic intermediates. The power of the reagent arises from its versatility - samarium diiodide can be used in processes ranging from functional group conversions to elaborate carbon-carbon bond-forming cyclization sequences that result in a dramatic increase in molecular complexity. In addition, reactions involving samarium diiodide often show high stereoselectivity as samarium ions can coordinate to Lewis basic sites on substrates and can direct the stereochemical course of reactions. The ability to fine-tune the reactivity of the reagent by the use of additives and co-solvents is an additional, attractive feature. Although samarium diiodide is used extensively by organic chemists, there is still a widely held view that the reagent can be difficult to prepare and use. In addition, samarium diiodide can mediate such a wide variety of organic chemistry that potential new users are often overawed by the extensive primary literature on the reagent. The objective of this book is to provide a concise, practical guide to the reagent. Rather than being a comprehensive review of the chemistry of samarium diiodide, this user-friendly book adopts an "an all you need to know" approach to the topic. The international authors are well-known for their work with the reagent and their expertise covers current developments in new reactivity and selectivity, applications in target synthesis, co-solvent and additive effects, coordination chemistry and mechanism. The book includes the best methods for preparing and handling the reagent, how solvents, co-solvents and additives alter reactivity, the basic mechanisms of reactions, common transformations using the reagent, and emerging areas in samarium diiodide chemistry. The authors have distilled the extensive primary literature to allow the reader to quickly grasp an understanding of the reagent and its utility. The illustrative practical procedures help the reader to prepare and use the reagent in the laboratory while references from the recent literature allow readers to pursue their interest in the popular reagent. The book also contains many illustrations and chemical schemes.
Download or read book Handbook of Plastics Joining written by Michael J. Troughton and published by William Andrew. This book was released on 2008-10-17 with total page 615 pages. Available in PDF, EPUB and Kindle. Book excerpt: The new edition of this bestselling reference provides fully updated and detailed descriptions of plastics joining processes, plus an extensive compilation of data on joining specific materials. The volume is divided into two main parts: processes and materials. The processing section has 18 chapters, each explaining a different joining technique. The materials section has joining information for 25 generic polymer families. Both sections contain data organized according to the joining methods used for that material. - A significant and extensive update from experts at The Welding Institute - A systematic approach to discussing each joining method including: process, advantages and disadvantages, applications, materials, equipment, joint design, and welding parameters - Includes international suppliers' directory and glossary of key joining terms - Includes new techniques such as flash free welding and friction stir welding - Covers thermoplastics, thermosets, elastomers, and rubbers.
Download or read book Current Catalog written by National Library of Medicine (U.S.) and published by . This book was released on with total page 1550 pages. Available in PDF, EPUB and Kindle. Book excerpt: First multi-year cumulation covers six years: 1965-70.
