Download or read book Handbook of Basic Pharmacokinetics Including Clinical Applications written by Wolfgang A. Ritschel and published by American Pharmacists Association (APhA). This book was released on 1999 with total page 590 pages. Available in PDF, EPUB and Kindle. Book excerpt: First published in 1976, this handbook is a consolidation of principles and techniques for practitioners, researchers and students involved in the various applications of pharmacokinetics. Twenty-six of the previous edition's 37 chapters have been revised. A new chapter entitled Extracorporeal Methods of Drug Removal addresses the clinical pharmacokinetic challenges that accompany renal replacement therapy. Pharmacokinetic data profiles for an additional 128 drugs have been added to the appendix, which now provides accessible information on 426 drugs.

Download or read book Handbook of Basic Pharmacokinetics Including Clinical Applications written by Wolfgang A. Ritschel and published by . This book was released on 1992 with total page 616 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Handbook of Basic Pharmacokinetics written by W. A. Ritschel and published by . This book was released on 1994 with total page 588 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Handbook of Basic Pharmacokinetics written by Wolfgang A. Ritschel and published by . This book was released on 1982-01-01 with total page 454 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Handbook of Basic Pharmacokinetics written by Wolfgang A. Ritschel and published by . This book was released on 1980 with total page 482 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Pharmacokinetics Basics to Applications written by Biswajit Mukherjee and published by Springer Nature. This book was released on 2022-03-17 with total page 354 pages. Available in PDF, EPUB and Kindle. Book excerpt: This textbook covers all the essential elements of pharmacokinetics, from basics to applications. It describes authoritative equations and methods on pharmacokinetic evaluation procedures with their importance. Each chapter of the book is supplemented with numerous illustrations and figures for easy understanding of the subject. The book presents mathematical techniques, step- by-step descriptive equations, and applicable statistical analysis methods for the easy understanding of the topic. Further, it covers the preclinical applications and methods of pharmacokinetic aspects. The book also contains mathematical problems and questions related to pharmacokinetics for students. Special emphasis is on recent pharmacokinetic methods and their applications for managing clinical data and biostatistical approaches based on the current literature. This book is primarily meant for researchers and students from academic institutions and to R&D professionals.

Download or read book Clinical Pharmacokinetics written by Soraya Dhillon and published by Pharmaceutical Press. This book was released on 2006 with total page 284 pages. Available in PDF, EPUB and Kindle. Book excerpt: Pharmacokinetics is the study of the process of drug absorption, distribution, metabolism and elimination. The aim of applying pharmacokinetic principles is to individualise the dose of drug, and optimise the outcome achieved in each patient. Its application reduces the chance of under-treatment, inadvertent poisoning, and dose related adverse effects. This new edition is specifically aimed at supporting undergraduate studies in pharmacokinetics, and has a strong emphasis on the application of pharmacokinetics in routine clinical practice. Clinical Pharmacokinetics also includes several case studies and 'questions and answers' to further aid understanding and revision.

Download or read book Handbook of Essential Pharmacokinetics Pharmacodynamics and Drug Metabolism for Industrial Scientists written by Younggil Kwon and published by Springer Science & Business Media. This book was released on 2007-05-08 with total page 302 pages. Available in PDF, EPUB and Kindle. Book excerpt: In the pharmaceutical industry, the incorporation of the disciplines of pharma- kinetics, pharmacodynamics, and drug metabolism (PK/PD/DM) into various drug development processes has been recognized to be extremely important for approp- ate compound selection and optimization. During discovery phases, the identifi- tion of the critical PK/PD/DM issues of new compounds plays an essential role in understanding their pharmacological profiles and structure-activity relationships. Owing to recent progress in analytical chemistry, a large number of compounds can be screened for their PK/PD/DM properties within a relatively short period of time. During development phases as well, the toxicology and clinical study designs and trials of a compound should be based on a thorough understanding of its PK/PD/DM properties. During my time as an industrial scientist, I realized that a reference work designed for practical industrial applications of PK/PD/DM could be a very valuable tool for researchers not only in the pharmacokinetics and drug metabolism departments, but also for other discovery and development groups in pharmaceutical companies. This book is designed specifically for industrial scientists, laboratory assistants, and managers who are involved in PK/PD/DM-related areas. It consists of thirteen chapters, each of which deals with a particular PK/PD/DM issue and its industrial applications. Chapters 3 and 12 in particular address recent topics on higher throughput in vivo exposure screening and the prediction of pharmacokinetics in humans, respectively. Chapter 8 covers essential information on drug metabolism for industrial scientists.

Download or read book Basic Pharmacokinetic Concepts and Some Clinical Applications written by Tarek A Ahmed and published by BoD – Books on Demand. This book was released on 2015-11-18 with total page 170 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book considers the basic principles of biopharmaceutics and pharmacokinetics. It also illustrates clinical pharmacokinetic applications, such as recirculatory models, common antimalarial drugs, and clinical pharmacokinetic principles in critically ill patients, which are essential for medical professionals. Undergraduate and postgraduate students can make use of the information presented. The contents of the book represent the authors points of view as well as clinical findings and basic concepts of pharmacokinetics and biopharmaceutics that are covered in textbooks.

Download or read book Clinical Pharmacokinetics Handbook written by Larry Bauer and published by McGraw-Hill Medical. This book was released on 2006 with total page 502 pages. Available in PDF, EPUB and Kindle. Book excerpt: Designed for pharmacists and clinicians responsible for adjusting drug dosages based on the patient blood serum concentrations and other parameters, this indispensable, portable reference offers a variety of ways to perform pharmacokinetic calculations. Features calculation methods, algorithms for choosing the best calculation method, and case studies.

Download or read book Handbook of Clinical Pharmacokinetic Data written by David B. Jack and published by Springer. This book was released on 1992-12-18 with total page 160 pages. Available in PDF, EPUB and Kindle. Book excerpt: This compendium of essential drug data helps when planning clinical research projects and choosing drugs with specific properties. As well as covering established drugs, data is presented on compounds about to be marketed or in the last stages of clinical development.

Download or read book Basic Pharmacokinetics Second Edition written by Mohsen A. Hedaya and published by CRC Press. This book was released on 2012-02-09 with total page 599 pages. Available in PDF, EPUB and Kindle. Book excerpt: Knowledge of pharmacokinetics is critical to understanding the absorption, distribution, metabolism, and excretion of drugs. It is therefore vital to those engaged in the discovery, development, and preclinical and clinical evaluation of drugs, as well as practitioners involved in the clinical use of drugs. Using different approaches accessible to a wide variety of readers, Basic Pharmacokinetics: Second Edition demonstrates the quantitative pharmacokinetic relations and the interplay between pharmacokinetic parameters. After a basic introduction to pharmacokinetics and its related fields, the book examines: Mathematical operations commonly used in pharmacokinetics Drug distribution and clearance and how they affect the rate of drug elimination after a single dose Factors affecting drug absorption following extravascular drug administration, the rate and extent of drug absorption, and drug bioequivalence The steady-state concept during constant rate intravenous infusion and during multiple drug administration Renal drug elimination, drug metabolism, multicompartment models, nonlinear pharmacokinetics, and drug administration by intermittent intravenous infusion Pharmacokinetic-pharmacodynamic modeling, noncompartmental pharmacokinetic data analysis, clearance concept from the physiological point of view, and physiological modeling Clinical applications of pharmacokinetics, including therapeutic drug monitoring, drug pharmacokinetics in special populations, pharmacokinetic drug-drug interactions, pharmacogenomics, and applications of computers in pharmacokinetics Accompanying the book is a CD-ROM with self-instructional tutorials and pharmacokinetic and pharmacokinetic-pharmacodynamic simulations, allowing visualization of concepts for enhanced comprehension. This learning tool received an award from the American Association of Colleges of Pharmacy for innovation in teaching, making it a valuable supplement to this essential text.

Download or read book Applied Clinical Pharmacokinetics written by Larry A. Bauer and published by McGraw Hill Professional. This book was released on 2007-09-22 with total page 842 pages. Available in PDF, EPUB and Kindle. Book excerpt: New sections on dosing strategies in all chapters. New chapter on sirolimus under the Immunosuppressants section. Essential information on drug dosing in special populations, including patients with renal and hepatic disease, obesity, and congestive heart failure. 30% of chapters extensively revised, others lightly updated

Download or read book Handbook of Clinical Pharmacokinetics written by L. F. Prescott and published by . This book was released on 1983 with total page 1216 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Pharmacokinetics and Toxicokinetics written by Mehdi Boroujerdi and published by CRC Press. This book was released on 2015-02-24 with total page 538 pages. Available in PDF, EPUB and Kindle. Book excerpt: Pharmacokinetics and Toxicokinetics provides an overview of pharmacokinetics and toxicokinetics in a comprehensible, interrelated, and applied manner. It integrates the principles held in common by both fields through a logical and systematic approach. The book presents mathematical descriptions of physiological processes employed in different appr

Download or read book Pharmacokinetics a Beginner s Guide written by John Kolthammer and published by Inst of Clinical Research. This book was released on 2007 with total page 52 pages. Available in PDF, EPUB and Kindle. Book excerpt: Everything you ever wanted to know about basic pharmacokinetics.

Download or read book Handbook of Basic and Clinical Ocular Pharmacology and Therapeutics written by Sunny Ohia and published by Academic Press. This book was released on 2022-07-26 with total page 673 pages. Available in PDF, EPUB and Kindle. Book excerpt: Handbook of Basic and Clinical Ocular Pharmacology and Therapeutics provides a review of the basic anatomy, physiology, biochemistry and pathology of the eye with a focus drug therapy, drug delivery and use of therapeutic medical miniature devices. An understanding of the pharmacological actions of drugs acting on the eye requires the student and health care practitioner to learn additional principles in basic and clinical sciences that are unique to this organ. As a sensory organ, the eye is relatively inaccessible to the systemic circulation due to the blood-vitreous, blood-aqueous and blood-retinal barriers. Consequently, the administration of drugs for therapeutic effects in the eye necessitates an understanding of physico-chemical properties of the molecules and pharmacokinetic principles involved in the access to its site of action via topical, intracameral and intravitreal administration. This book includes information on the general principles of pharmacokinetics and pharmacodynamics of drugs as it pertains to the eye and in combating ocular disorders and diseases. Using a disease-themed approach, the book discusses basic and clinical pharmacological principles involved in the therapy of these diseases including the ocular side effect of systemically-administered drugs, drugs used in ophthalmic surgery and miscellaneous agents, the therapeutic utility of biologics, drug conjugates, combination products, gene and cellular therapy are also covered. Handbook of Basic and Clinical Ocular Pharmacology and Therapeutics is useful as a primary and secondary source of reference for up-to-date information about the pharmacological mechanisms of action, pharmacokinetics, side effects, drug-drug interactions and therapeutic indications of drugs for pharmacologists, pharmaceutical scientists, students in the health care disciplines (nursing, pharmacy, optometry, medical), and practitioners in optometry and ophthalmology. Explains the mechanisms of action, side-effects and therapeutic uses of drugs, biologics, miniature devices, gene and cellular therapies for the eye Provides a comprehensive review of the anatomy, physiology, biochemistry, pharmacology, microbiology, genetics and pathology of parts of the eye involved in drug therapy to combat eye disorders and diseases Explores the pharmacological and clinical basis of drugs, drug conjugates, combination products used in the treatment of anterior and posterior segment diseases