Download or read book Growth Factors in Development written by and published by Academic Press. This book was released on 2011-11-07 with total page 269 pages. Available in PDF, EPUB and Kindle. Book excerpt: This new volume of the renowned serial Current Topics in Developmental Biology covers the important features of growth factors in development. With an international board of authors, this volume will be invaluable for researchers in cell, developmental and molecular biology. Provides researchers an overview and synthesis of the latest research findings and contemporary thought in the area This volume provides an up-to-date and timely perspective

Download or read book Holland Frei Cancer Medicine written by Robert C. Bast, Jr. and published by John Wiley & Sons. This book was released on 2017-03-10 with total page 2004 pages. Available in PDF, EPUB and Kindle. Book excerpt: Holland-Frei Cancer Medicine, Ninth Edition, offers a balanced view of the most current knowledge of cancer science and clinical oncology practice. This all-new edition is the consummate reference source for medical oncologists, radiation oncologists, internists, surgical oncologists, and others who treat cancer patients. A translational perspective throughout, integrating cancer biology with cancer management providing an in depth understanding of the disease An emphasis on multidisciplinary, research-driven patient care to improve outcomes and optimal use of all appropriate therapies Cutting-edge coverage of personalized cancer care, including molecular diagnostics and therapeutics Concise, readable, clinically relevant text with algorithms, guidelines and insight into the use of both conventional and novel drugs Includes free access to the Wiley Digital Edition providing search across the book, the full reference list with web links, illustrations and photographs, and post-publication updates

Download or read book Cooperation of Liver Cells in Health and Disease written by Z. Kmiec and published by Springer Science & Business Media. This book was released on 2013-06-29 with total page 154 pages. Available in PDF, EPUB and Kindle. Book excerpt: It is only during the last decade that the functions of sinusoidal endothelial cells, Kupffer cells, hepatic stellate cells, pit cells and other intrahepatic lymphocytes have been better understood. The development of methods for isolation and co-culturing various types of liver cells has established that they communicate and cooperate via secretion of various intercellular mediators. This monograph summarizes multiple data that suggest the important role of cellular cross-talk for the functions of both normal and diseased liver. Special features of the book include concise presentation of the majority of detailed data in 19 tables. Original schemes allow for the clear illustration of complicated intercellular relationships. This is the first ever presentation of the newly emerging field of liver biology, which is important for hepatic function in health and disease and opens new avenues for therapeutic interventions.

Download or read book Growth Factors in Mammalian Development written by I. Y. Rosenblum and published by CRC Press. This book was released on 2021-05-30 with total page 198 pages. Available in PDF, EPUB and Kindle. Book excerpt: The purpose of this volume is to review and discuss key growth factor systems that have been implicated in embryogenesis. Emphasis is placed on the insulin family of peptides, including insulin and the structurally and functionally related insulin-like growth factors. The initial chapters provide a review of basic topics, including developmental genetics, energy metabolism and hormonal signaling mechanisms, which are important prerequisites to the central theme that follows. The book concludes with a brief review of oncogene expression in early development; this new field has contributed significantly to our understanding of how mitogenic signals activate genetic elements responsible for embryonic growth and development. This book presents information important to cell biologists, endocrinologists, biological chemists, and developmental biologists.

Download or read book Growth Factors in Perinatal Development written by Reginald C. Tsang and published by Raven Press (ID). This book was released on 1993 with total page 152 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Fibroblast Growth Factors written by Xiaokun Li and published by Academic Press. This book was released on 2018-06-20 with total page 576 pages. Available in PDF, EPUB and Kindle. Book excerpt: Fibroblast Growth Factors presents research and results from the leading global research group on FGF, providing up-to-date and comprehensive coverage of the field. The book describes the history, basic research and growth engineering technology involved with FGFs, while also introducing detailed research methods. It comprises eight chapters that detail successes and problems in relation to wound healing of engineered growth factors and considers injury repair and regeneration, non-mitogenic mutants, structure modification, pathology, physiology, pharmacology, development, FGF/FGFR inhibitors, bioengineering, and new drug development. It will serve as a key reference book for researchers working on FGFs. Focuses on the growth engineering aspects of FGF-based drug development and its clinical applications Presents useful information on the history of FGFs, along with basic research and growth engineering technology Provides detailed, practical research methods and results obtained on FGFs Considers the successes and problems in engineering technology Offers up-to-date, comprehensive coverage from the world’s leading research group

Download or read book The Role of Growth Factors in Development written by Laura Gillespie and published by . This book was released on 1991 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Insulin Like Growth Factors in Development Cancers and Aging written by Haim Werner and published by MDPI. This book was released on 2021-08-30 with total page 196 pages. Available in PDF, EPUB and Kindle. Book excerpt: This Special Issue of Cells on “Insulin-Like Growth Factors in Development, Cancers and Aging” provides a collection of modern articles dealing with the role of insulin-like growth factors (IGF1) in cancer biology, aging and development. Featured articles explore basic and clinical aspects of the IGF1 system, including post-genomic analyses as well as novel approaches to target the IGF1 receptor (IGF1R) in oncology.

Download or read book Growth Factors and Their Receptors in Cell Differentiation Cancer and Cancer Therapy written by G V Sherbet and published by Elsevier. This book was released on 2011-07-12 with total page 368 pages. Available in PDF, EPUB and Kindle. Book excerpt: Recent years have seen a considerable emphasis on growth factors and the elucidation of their mode of function, which has led to the recognition that growth factors, their receptors as well as downstream elements of signalling associated with their function might be potential targets in therapeutic management of human diseases. Humanised monoclonal antibodies raised against growth factor receptors have proved to be valuable for targeted cancer treatment and in patient management. This book reviews the latest developments providing insights into the signalling processes involved in morphogenesis and pathogenesis with emphasis on using the elements of the signalling cascades as targets for therapeutic deployment. Provides a fundamental understanding of the basic functions of growth factors and their receptors, describing how they are linked in biological processes Aids the development of therapeutic treatments for cancer Focuses on the interrelationships and convergence of growth factors and their receptors in development and pathogenesis and encourages greater cooperation and integration in the areas of developmental, cancer and cancer therapeutic research

Download or read book Handbook of Growth Factors written by Enrique Pimentel and published by CRC Press. This book was released on 1994-06-02 with total page 386 pages. Available in PDF, EPUB and Kindle. Book excerpt: Volume I of this book provides a comprehensive discussion of the factors involved in regulation of the cell cycle, the general biological properties of growth factors, and the receptor and postreceptor mechanisms of action of these signaling agents. It evaluates the possible role of growth factors in the regulation of proto-oncogene and tumor suppressor gene expression, and the development of neoplastic processes is discussed in detail.

Download or read book Signal Transduction in Cancer written by David A. Frank and published by Springer Science & Business Media. This book was released on 2002-12-31 with total page 358 pages. Available in PDF, EPUB and Kindle. Book excerpt: One of the most exciting areas of cancer research now is the development of agents which can target signal transduction pathways that are activated inappropriately in malignant cells. The understanding of the molecular abnormalities which distinguish malignant cells from their normal counterparts has grown tremendously. This volume summarizes the current research on the role that signal transduction pathways play in the pathogenesis of cancer and how this knowledge may be used to develop the next generation of more effective and less toxic anticancer agents. Series Editor comments: "The biologic behavior of both normal and cancer cells is determined by critical signal transduction pathways. This text provides a comprehensive review of the field. Leading investigators discuss key molecules that may prove to be important diagnostic and/or therapeutic targets."

Download or read book Basic Neurochemistry written by George J. Siegel and published by Lippincott Raven. This book was released on 1999 with total page 1216 pages. Available in PDF, EPUB and Kindle. Book excerpt: Illustrations by Lorie M. Gavulic, MFA Sponsored by the American Society for Neurochemistry.

Download or read book Growth Factors and Signal Transduction in Development written by Marit Nilsen-Hamilton and published by Wiley-Liss. This book was released on 1994-06 with total page 272 pages. Available in PDF, EPUB and Kindle. Book excerpt: Describes the interactions of growth factors and their receptors, and the subsequent signal transduction pathways that they activate. Emphasis is placed on the role of these signals in directing developmental events. The contributors provide a mixture of biophysical and biochemical perspectives.

Download or read book Growth Factors in Differentiation and Development written by Royal Society (Great Britain) and published by . This book was released on 1990 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Growth Factors in Reproduction written by David W. Schomberg and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 357 pages. Available in PDF, EPUB and Kindle. Book excerpt: The critical role of growth factors in normal as well as abnormal cellular growth and function has become overwhelmingly apparent in recent years. The significant advances in reproductive biology within this rapidly expanding field were highlighted at the Serono Symposia, USA, symposium entitled Growth Factors in Reproduc tion. The conference focused on growth factors as polyfunctional regulators of growth and development in the reproductive system. The program was organized into five areas: (1) growth factors as polyfunctional regulators of growth and development, (2) growth factors and gonadal function, (3) regulation of normal and neoplastic mammary growth, (4) regulatory peptides in reproductive tract development and function, and (5) embryo-maternal signaling. This volume constitutes the contributions ofthe invited symposium speakers and is organized into sections representing the five topic areas of the sessions. Drs. Eli Y. Adashi, Robert B. Dickson, David C. Lee, James Hammond, John A. McLachlan, and R. Michael Roberts, who served as chairmen ofthese sessions, not only provided invaluable advice and assistance in organizing the symposium, but contributed significantly to its content. The enthusiasm and esprit de corps of the poster presenters and discussion participants also helped make this symposium succeed as the first of its kind. Finally, special thanks are due Drs. James Posillico and Lisa Kern ofSerono Symposia, USA, for their guidance and support in the conception and planning of the symposium and in the publication of this volume.

Download or read book The Fibroblast Growth Factor Family written by Andrew Baird and published by . This book was released on 1991 with total page 542 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Growth Factors written by Choh Hao Li and published by Elsevier. This book was released on 1984-12-28 with total page 329 pages. Available in PDF, EPUB and Kindle. Book excerpt: Hormonal Proteins and Peptides: Growth Factors, Volume XII focuses on the chemistry and biology of nerve growth factor (NGF), insulin-like growth factors/somatomedins/multiplication-stimulating activity (IGFs/SMs/MSA), fibroblast growth factors (FGFs), platelet-derived growth factor (PDGF), and skeletal growth factor (SGF). This book discusses the development of growth factors in cell proliferation, differentiation, and malignancy. Organized into eight chapters, this volume starts with an overview of the findings on the structural and biological properties of NGF. This text then discusses the identical amino acid sequences of IFG-I and SM-c and explains as well the similarities in the structure of IFG-II and MSA. Other chapters present a thorough discussion of human PDGF, with emphasis on the link between the PDGF and the simian sarcoma virus gene product. This book discusses as well the mechanism of action of the pituitary and brain FGF. The final chapter deals with the discovery, isolation, and characterization of the biological activities of epidermal growth factor (EGF). This book is a valuable resource for biochemists, endocrinologists, and physicians.