Download or read book Golgi written by Paolo Mazzarello and published by . This book was released on 2010 with total page 552 pages. Available in PDF, EPUB and Kindle. Book excerpt: The life of Camillo Golgi was an extraordinary intellectual adventure in three major fields of biology and medicine, namely neuroscience, emerging cell biology, and the new science of medical microbiology. in 1873, Golgi published the description of a revolutionary histological technique which allowed one, for the first time, to visualize a single nerve cell with all its ramifications, and which could be followed and analyzed even at a great distance from the cell bodies. The so-called "black reaction" (later named the "Golgi method") provided the spark to a truly scientific revolution which allowed the morphology and the basic architecture of the cerebral tissue to be evidenced in all its complexity, thus contributing to the foundation of modern neuroscience. It has been written that, in the same way Galileo Galilei was able to find new stars observing any sky region with his telescope. Golgi was able to find new nervous structures and nerve cells by applying his black reaction to any brain region. Finally, the details of the most complex structure in the known universe, the brain, could be characterized. Golgi's black reaction is just one of his many successes and contributions to society. As this book illustrates, he has also strongly contributed to the development of cell biology with the "internal reticular apparatus" (later called the "Golgi apparatus") and to medical microbiology with his studies on malaria. Engrossing and authoritative, Golgi: A Biography of the Founder of Modern Neuroscience, is a detailed account of one of the most prominent European researchers of his time.
Download or read book Molecular Biology of the Cell written by and published by . This book was released on 2002 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book The Golgi Apparatus and Centriole written by Malgorzata Kloc and published by Springer. This book was released on 2020-09-04 with total page 529 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume takes a closer look how the cell organelles Golgi apparatus (also known as the Golgi complex or Golgi body), and centriole are structurally and functionally intertwined. Initially, it was believed that the role of Golgi complex is limited to the packaging and preparation for secretion of various cellular proteins, while the centriole participates in cell division and cilia formation. However, since their discovery nearly 200 years ago, it became clear that these two organelles are interacting, and that their functions are much more complex and far reaching than previously thought. Recent findings indicate that the Golgi–Centriole relationship may be important for directional protein transport, cell polarization and cell cycle progression. Current studies indicate that Golgi and centriole also participate in development and act as cellular and immunological sensors, and that their abnormalities lead to cell and developmental abnormalities, Alzheimer, cancer, various lipid disorders and neurological and immunological diseases in humans. This volume combines the latest information on the structure, molecular composition, and roles of Golgi and centriole in various cellular functions and diseases. The better understanding of the Golgi–centriole interactions may lead to the development of novel therapies for the treatment of various diseases, including cancer.
Download or read book Essentials of Glycobiology written by Ajit Varki and published by CSHL Press. This book was released on 1999 with total page 694 pages. Available in PDF, EPUB and Kindle. Book excerpt: Sugar chains (glycans) are often attached to proteins and lipids and have multiple roles in the organization and function of all organisms. "Essentials of Glycobiology" describes their biogenesis and function and offers a useful gateway to the understanding of glycans.
Download or read book The Golgi Apparatus written by Eric G. Berger and published by Springer Science & Business Media. This book was released on 1997 with total page 328 pages. Available in PDF, EPUB and Kindle. Book excerpt: In 1898 Camillo Golgi reported his newly observed intracellular structure, the apparato reticolare interno, now universally known as the Golgi Apparatus. The method he used was an ingenious histological technique (La reazione nera) which brought him fame for the discovery of neuronal networks and culminated in the award of the Nobel Prize for Physiology and Medicine in 1906. This technique, however, was not easily reproducible and led to a long-lasting controversy about the reality of the Golgi apparatus. Its identification as a ubiquitous organelle by electron microscopy turned out to be the breakthrough and incited an enormous wave of interest in this organelle at the end of the sixties. In recent years immunochemical techniques and molecular cloning approaches opened up new avenues and led to an ongoing resurgence of interest. The role of the Golgi apparatus in modifying, broadening and refining the structural information conferred by transcription/translation is now generally accepted but still incompletely understood. During the coming years, this topic certainly will remain center stage in the field of cell biology. The centennial of the discovery of this fascinating organelle prompted us to edit a new comprehensive book on the Golgi apparatus whose complexity necessitated the contributions of leading specialists in this field. This book is aimed at a broad readership of glycobiologists as well as cell and molecular biologists and may also be interesting for advanced students of biology and life sciences.
Download or read book Golgi Atlas of the Postnatal Mouse Brain written by Facundo Valverde and published by Springer Science & Business Media. This book was released on 2013-06-29 with total page 148 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Atlas provides a complete overview of all major structures of the mouse brain that can be identified in Golgi preparations. The most important feature is its three-dimensional integrity since all structures and nerve tracts can be followed from one section to the next one with uninterrupted continuity. The Golgi Atlas presents a series of camera lucida drawings of the entire telencephalon and upper brain stem of the young postnatal mouse in 24 transverse, 11 sagittal and 15 horizontal planes. The drawings were prepared from selected brains stained in toto with the Golgi method, that have been serially sectioned in the three orthogonal planes. The text includes an introduction of the material and methods used for the construction of this Atlas and a survey with a complete bibliography on the previous studies made with the Golgi method in Rodents. In this account, a number of issues concerning particular anatomical details are considered in relation to the interpretations obtained by other students. Reference is made to some relevant reviews and key articles.
Download or read book The Golgi Apparatus written by James Morré and published by Springer Science & Business Media. This book was released on 2008-12-11 with total page 311 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Golgi apparatus (GA) is typically comprised of a series of five to eight cup-shaped, membrane-covered sacs called cisternae that look something like a stack of deflated balloons. The GA is often considered the "distribution and shipping department" for the cell's chemical products. This book traces the first 100 years of GA discovery from the first published accounts from Pavia, Italy, in 1898 to the Centenary Celebration in Pavia, Italy, in 1998 to our most recent discoveries. It summarizes the past 50 years beginning with the modern era of GA discovery, leading up to the present era with almost exclusive focus on molecular biology.
Download or read book The Hidden Structure written by Paolo Mazzarello and published by . This book was released on 1999 with total page 460 pages. Available in PDF, EPUB and Kindle. Book excerpt: Camillo Golgi (1843-1926) is widely regarded as one of the founders of modern neuroscience. In 1873, he discovered the black reaction -- a histological stain which proved to be a revolutionary method for studying the structure of the nervous system. To this day, the Golgi stain is widely used. And for every student of medicine or biology, Golgi's name is synonymous with one of the basic structures in the cell: Golgi Apparatus. He discovered the apparatus in 1898 and, as a result, is among the most widely cited biologist in scientific literature. But this was only one of Golgi's many contributions to scientific research. He also devised a system for the classification of neurons on the basis of axonal distribution, identified a type of cell in the cerebellum, and described the malarial cycle in the human. His discoveries were rich with therapeutic implications, and his remarkable achievements earned him a Nobel Prize for Medicine in 1906. Most books of biology or medicine point out that Golgi is one of the giants of 19th Century scientific endeavor, but he continues to remain a relatively unknown figure in the history of neuroscience and cell biology. This long-awaited biography, in a new translation from the Italian, is a fascinating analysis of Golgi's experiments, ideas, and personal life. It is welcomed by anyone who has ever learned about his brilliant discoveries but wondered about Golgi, the person. In fact, all those with an interest in the history of science, and cell biology in particular, as well as those involved in neuroscience, medicine, and biochemistry will benefit from this book.
Download or read book The Golgi Apparatus written by Alexander A. Mironov and published by Springer Science & Business Media. This book was released on 2009-03-04 with total page 714 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book summarizes all new data obtained after development of methods of Golgi complex sub fractionation, molecular biology and microscopy. It collects the full range of expertise, different points of view and different approaches. The book is devoted to molecular modes of the function of the Golgi apparatus as a whole, taking into account all experimental data. The book aims to make the functional organization of the Golgi apparatus more understandable.
Download or read book The Golgi Apparatus written by Eric Berger and published by Birkhäuser. This book was released on 2012-12-06 with total page 306 pages. Available in PDF, EPUB and Kindle. Book excerpt: In 1898 Camillo Golgi reported his newly observed intracellular structure, the apparato reticolare interno, now universally known as the Golgi Apparatus. The method he used was an ingenious histological technique (La reazione nera) which brought him fame for the discovery of neuronal networks and culminated in the award of the Nobel Prize for Physiology and Medicine in 1906. This technique, however, was not easily reproducible and led to a long-lasting controversy about the reality of the Golgi apparatus. Its identification as a ubiquitous organelle by electron microscopy turned out to be the breakthrough and incited an enormous wave of interest in this organelle at the end of the sixties. In recent years immunochemical techniques and molecular cloning approaches opened up new avenues and led to an ongoing resurgence of interest. The role of the Golgi apparatus in modifying, broadening and refining the structural information conferred by transcription/translation is now generally accepted but still incompletely understood. During the coming years, this topic certainly will remain center stage in the field of cell biology. The centennial of the discovery of this fascinating organelle prompted us to edit a new comprehensive book on the Golgi apparatus whose complexity necessitated the contributions of leading specialists in this field. This book is aimed at a broad readership of glycobiologists as well as cell and molecular biologists and may also be interesting for advanced students of biology and life sciences.
Download or read book The Golgi Apparatus written by W.G. Whaley and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 281 pages. Available in PDF, EPUB and Kindle. Book excerpt: A comprehensive review of the Golgi apparatus and its functioning would require a multi-volume publication and not a monograph and it would be so repetitious as to discourage the reader. The requirement at this stage is for a reinterpretation of the character and functioning of this organelle since the last major interpretations have concentrated on its role in secretion and it has now been shown to be a component of essentially all cells whether or not they have been traditionally emphasized as secreting cells. As a conse quence the efforts have been placed on the common characteristics of the organelle, a postulate concerning its functioning in cells generally, and the details of variations where these seem important. The major acknowledgment of assistance in compiling the material must go to the investigators whose contributions, sometimes positive and sometimes of a character to spur additional investigations, allowed the development of this postulate. The paper has been prepared with the detailed assistance of Dr. MARIANNE DAUWALDER who, by her own studies and her insight into the significance of other studies, has been a working partner of many years in the development of a general hypothesis and whose knowledge of investiga tions of the Golgi apparatus is great enough to let her call attention to instances of support and contention with the general functional hypothesis that has been involved.
Download or read book Golgi Dynamics in Physiological and Pathological Conditions written by Jaakko Saraste and published by Frontiers Media SA. This book was released on 2020-03-04 with total page 359 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Golgi Apparatus written by Christopher J. Hawkins and published by . This book was released on 2011 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Golgi apparatus is an organelle found in most eukaryotic cells. The primary function of the Golgi apparatus is to process and package macromolecules, such as proteins and lipids, after their synthesis and before they make their way to their destination. This book presents topical research data in the study of Golgi apparatus, including Golgi organization and stress sensing; signaling pathways controlling mitotic Golgi breakdown in mammalian cells; the role of Golgi apparatus in the biological mechanisms of hypericin-mediated photodynamic therapy; the role of the Trans-Golgi Network (TGN) in the sorting of nonenzymic lysosomal proteins; and the mechanisms involving the role of Golgi apparatus alteration in neurological disorders triggered by manganese.
Download or read book The Golgi Apparatus and the Plant Secretory Pathway written by David G. Robinson and published by CRC Press. This book was released on 2003 with total page 280 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Golgi apparatus is a key component of plant and animal cells. Its primary role is to orchestrate the targeting of proteins and lipids to specific cellular destinations. With advances in our understanding of how the Golgi apparatus operates in plants, it will become possible to manipulate both the timing and the site of delivery of macromolecules, thus influencing plant growth and development. This volume concentrates on the major developments of the last few years, drawing attention to the distinct differences between the plant and non-plant Golgi apparatus and highlighting unsolved problems. A chapter is included on the yeast Golgi apparatus.
Download or read book The Golgi Apparatus written by Alexander A. Mironov and published by Springer Science & Business Media. This book was released on 2009-03-04 with total page 714 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book summarizes all new data obtained after development of methods of Golgi complex sub fractionation, molecular biology and microscopy. It collects the full range of expertise, different points of view and different approaches. The book is devoted to molecular modes of the function of the Golgi apparatus as a whole, taking into account all experimental data. The book aims to make the functional organization of the Golgi apparatus more understandable.
Download or read book The Golgi Apparatus and Centriole written by Malgorzata Kloc and published by Springer Nature. This book was released on 2019-08-21 with total page 529 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume takes a closer look how the cell organelles Golgi apparatus (also known as the Golgi complex or Golgi body), and centriole are structurally and functionally intertwined. Initially, it was believed that the role of Golgi complex is limited to the packaging and preparation for secretion of various cellular proteins, while the centriole participates in cell division and cilia formation. However, since their discovery nearly 200 years ago, it became clear that these two organelles are interacting, and that their functions are much more complex and far reaching than previously thought. Recent findings indicate that the Golgi–Centriole relationship may be important for directional protein transport, cell polarization and cell cycle progression. Current studies indicate that Golgi and centriole also participate in development and act as cellular and immunological sensors, and that their abnormalities lead to cell and developmental abnormalities, Alzheimer, cancer, various lipid disorders and neurological and immunological diseases in humans. This volume combines the latest information on the structure, molecular composition, and roles of Golgi and centriole in various cellular functions and diseases. The better understanding of the Golgi–centriole interactions may lead to the development of novel therapies for the treatment of various diseases, including cancer.
Download or read book Functional Morphology of the Golgi Apparatus written by Margit Pavelka and published by Springer Science & Business Media. This book was released on 2013-11-09 with total page 104 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book gives a survey of the architecture of the Golgi apparatus, as revealed by morphological and cytochemical studies with a variety of cell types. The results presented include demonstrations of Golgi architecture in the course of cell differentiation, at varying functional cellular states, and under the influence of microtubule-disrupting agents. Emphasis is particularly placed on the organization of subsections of the Golgi apparatus and the questions of how Golgi subsections may be related to functional subcompartments of the Golgi system. By means of affinity-cytochemical approaches, using a palette of lectins of diverse sugar specificities, it is shown that functional subcompartments can be distributed in the complex Golgi system irrespective of the morphological subdivision in cis-medial-trans-transmost subsections. The use of pre- and post-embedment lectin-cytochemical approaches as a tool for the localization of functional Golgi subcompartments is of particular interest, especially as some of the lectins have been used in these approaches for the first time. This book intends to provide synoptic information on the architecture of the Golgi apparatus, its wide variability and possible arrangements of Golgi subcompartments.
