Download or read book Gene and Cell Therapy Biology and Applications written by Giridhara R. Jayandharan and published by Springer. This book was released on 2018-09-12 with total page 316 pages. Available in PDF, EPUB and Kindle. Book excerpt: Recent advances in stem cell biology, nanotechnology and gene therapy have opened new avenues for therapeutics. The availability of molecular therapeutics that rely on the delivery of DNA, RNA or proteins, harnessing enhanced delivery with nanoparticles, and the regenerative potential of stem cells (adult, embryonic or induced pluripotent stem cells) has had a tremendous impact on translational medicine. The chapters in this book cover a range of strategies for molecular and cellular therapies for human disease, their advantages, and central challenges to their widespread application. Potential solutions to these issues are also discussed in detail. Further, the book addresses numerous advances in the field of molecular therapeutics that will be of interest to the general scientific community. Lastly, the book provides specific examples of disease conditions for which these strategies have been transferred to the clinic. As such, it will be extremely useful for all students, researchers and clinicians working in the field of translational medicine and molecular therapeutics.
Download or read book Shadows at Noon written by Joya Chatterji and published by Penguin Random House India Private Limited. This book was released on 2023-07-24 with total page 592 pages. Available in PDF, EPUB and Kindle. Book excerpt: Shadows at Noon is an ambitious synthesis of decades of research and scholarship which explores the key strands of South Asian history in the twentieth century with clarity and authority. Unlike other narrative histories of the subcontinent that concentrate exclusively on politics, here food, leisure and the household are given equal importance to discussions of nationhood, the development of the state and patterns of migration. While it tells the subcontinent's story from the British Raj to independence and partition and on to the forging of the modern nations of India, Pakistan and Bangladesh, the book's structure is thematic rather than chronological. Each of the chapters illuminates on overarching theme or sphere that has shaped South Asia over the course of the century. This format allows the reader to explore particular issues such as the changing character of nationalism or food consumption over time and in depth. Shadows at Noon is a bold, innovative and personal work that pushes back against standard narratives of 'inherent' differences between India, Pakistan and Bangladesh. Its purpose is to make contemporary South Asia intelligible to readers who are fascinated by the subcontinent's cultural vibrancy and diversity but are often perplexed by its social and political makeup. And it illuminates the many aspects that its people have in common rather than what divides them.
Download or read book Pandemic of Diabetes and Prediabetes Prevention and Control An Issue of Endocrinology and Metabolism Clinics of North America EBook written by K M Venkat Narayan and published by Elsevier Health Sciences. This book was released on 2021-08-17 with total page 281 pages. Available in PDF, EPUB and Kindle. Book excerpt: - Provides in-depth, clinical reviews on diabetes and prediabetes prevention and control, providing actionable insights for clinical practice. - Presents the latest information on this timely, focused topic under the leadership of experienced editors in the field; Authors synthesize and distill the latest research and practice guidelines to create these timely topic-based reviews.In this issue of Endocrinology and Metabolism Clinics, guest editor K M Venkat Narayan brings considerable expertise to the topic of diabetes and prediabetes.
Download or read book Health Safety and Well Being of Workers in the Informal Sector in India written by Sigamani Panneer and published by Springer. This book was released on 2019-07-25 with total page 297 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book focuses on the core problems of occupational health, safety and well-being of workers in the informal sector in developing countries, where it accounts for most of the rural labour force and a substantial percentage of the urban labour force. The sector is characterised by low incomes, unstable employment and lack of protection in the form of legislation/policies or trade unions. Though some health and problem-solving measures have been introduced, a focused academic effort to address the problems confronting workers in the unorganised sector, or informal economy, is lacking. The book evaluates workers’ physical and mental health in the context of labour migration, social inclusion of minorities and the differently abled, provisions for women workers, demonetisation, occupational safety for hazardous work, and in connection with various areas of informal work, e.g. agriculture, construction, transportation, sanitation, tanning, the tobacco industry, powerloom industry, surrogacy, and self-employment. It provides a well-rounded description of an analytical reflection on the challenges these workers face and focuses on social policy changes to help alleviate them. Accordingly, it offers a valuable asset for researchers and students interested in development studies, the sociology of work, health and labour economics, public health, and social work.
Download or read book Neuroepidemiology in Resource Limited Areas written by Ding Ding and published by Frontiers Media SA. This book was released on 2020-06-04 with total page 134 pages. Available in PDF, EPUB and Kindle. Book excerpt: Neuroepidemiology is a branch of epidemiology involving the study of neurological disease distribution and determinants of frequency in human populations. Neuroepidemiology has been perceived for a long time as a science of incidence, prevalence, risk factors, natural history and prognosis of neurological disorders. However, the other integral part of neuroepidemiology is experimental neuroepidemiology, which is research based on clinical trials of effectiveness or efficacy of various interventions in neurological disorders. Neuroepidemiological researches have been conducted since 1960’s, with the development of epidemiological methodology and advance of the clinical neurology. Most improvement of neuroepidemiology was in western countries, largely in US and European countries. This study field has been developed quite late in resourcelimited areas, where 60% of world’s populations are living in. Disease burden of neurological disorders, such as stroke, epilepsy, migraine, neurodegenerated diseases (AD, PD), multiple sclerosis (MS), amyotrophic lateral sclerosis (ALS), are extremely heavy in low and middle income countries (LAMICs), especially with the increasing aging population in these regions. Because of their progressive and disabling nature, these neurological disorders have major adverse personal, social, and economic consequences. Prevention and early detection are critical, because there are no cures and the clinical diagnosis typically occurs after substantial and often irreversible neuronal loss.
Download or read book Public Health Approach to Cardiovascular Disease Prevention Management written by Dorairaj Prabhakaran and published by CRC Press. This book was released on 2022-12-29 with total page 270 pages. Available in PDF, EPUB and Kindle. Book excerpt: Cardiovascular Diseases (CVDs) are the number one cause of death and disability globally, being the most important public health problem that needs to be tackled as more people die annually from CVDs than from any other cause. Over three-quarters of CVD deaths take place in low- and middle-income countries. This book on cardiovascular diseases provides an overview of the global and regional challenges associated with CVDs. Coupled with case studies and theoretical concepts, it helps the reader to contextualize CVDs in the broader public health system and the administrative aspects of practicing CVD control approaches for improved population health in their local setting. Key Features:1. Covers existing and emerging issues in cardiovascular disease epidemiology and prevention. 2. Has a multidisciplinary approach in content and audience. 3. Connects with health systems and relevant sustainable development goals. 4. Provides case studies for enabling readers to understand and apply evidence-based solutions to key public health issues. 5. Has inputs from globally renowned public health experts.
Download or read book Improving maternal nutrition in India through integrated hot cooked meal programs A review of implementation evidence written by Kachwaha, Shivani and published by Intl Food Policy Res Inst. This book was released on 2021-05-20 with total page 34 pages. Available in PDF, EPUB and Kindle. Book excerpt: A notable approach to addressing maternal undernutrition during pregnancy in India in recent years has been the integration of hot-cooked meals (HCM) for pregnant and lactating women together with the provision of other health/nutrition services. Called the One Full Meal (OFM) program, these efforts aim to improve maternal nutrition and health across India by bundling center-based HCM with other nutrition services and behavior change communication implemented through the Integrated Child Development Services (ICDS) scheme. The program is offered at anganwadi centers (AWCs) and has been implemented in eight states in India, including Andhra Pradesh, Chhattisgarh, Gujarat, Karnataka, Maharashtra, Telangana, Madhya Pradesh, and Uttar Pradesh. Although the OFM program has been implemented since 2013, there is limited consolidated insight on its effectiveness or on broader lessons for implementation. The objectives of this evidence review of the OFM program are, therefore, to (1) compare the different state OFM program models on their objectives, implementation elements, cost norms and monitoring mechanisms; (2) develop program impact pathways on the potential ways in which the program could influence intended outcomes; and (3) examine the availability of evidence underpinning the program’s intended pathways to impact.
Download or read book Life under Lockdown written by Sanjai Bhatt and published by Papyrus Scrolls Publications. This book was released on 2021-11-11 with total page 400 pages. Available in PDF, EPUB and Kindle. Book excerpt: Life under Lockdown- Lived Experiences and Lessons Learnt is an edited book with contributions from 32 people during the COVID-19 pandemic. The contributors to this volume are social work professionals, educators, academicians, bureaucrats, researchers, and even students. Prof. Bhatt presents the narratives of the COVID lockdown from different spheres of life and wove them together to present a volume that offers new perspectives of any such situation ever faced in the future. This book will help social work practitioners, academicians, and people who have an inclination towards social work or related disciplines.
Download or read book Rural Women s Sexuality Reproductive Health and Illiteracy written by Gisele Maynard-Tucker and published by Lexington Books. This book was released on 2014-12-11 with total page 157 pages. Available in PDF, EPUB and Kindle. Book excerpt: Based on twenty-five years of fieldwork, Rural Women’s Sexuality, Reproductive Health, and Illiteracy: A Critical Perspective on Development examines rural women’s behaviors towards health in several developing countries. These women are confronted with many factors: gender inequalities, violence from partners, and lack of economic independence. The book also gives insight into the general weakness of the health systems in place and questions the progress of numerous international conferences ICPD (International Conference on Population and Development) and MDGs (Millennium Development Goals) along with WHO (The World Health Organization) Frame Work for Action, UNFPA (United Nations Population Fund) and CEDAW (Committee on the Elimination of Discrimination Against Women) all supporting women’s empowerment as related to violence, education, and reproductive health. Chapters provide numerous concrete examples and vignettes describing constraints on women in a variety of countries related to their intimate lives and their struggle between traditional and modern medicine. Widely practiced clandestine sex work is a challenge to HIV/AIDS programs. The book examines the women who choose clandestine sex work and their clients’ sexual behavior and attitudes toward prostitution and HIV prevention. It also explores the negotiations between promiscuous, migratory men, and the ties of sexuality and fertility that women use to tie them to a male partner. The book argues for effective delivery of healthcare programs accompanied by multi-lateral responses from the civil society, governments, donors and agencies. Rural Women’s Sexuality, Reproductive Health, and Illiteracy is a useful resource scholars, as well as consultants and staff working in development agencies and public health.
Download or read book Climate Change Variability and Sustainable Food Systems written by Victor Owusu and published by Frontiers Media SA. This book was released on 2023-02-16 with total page 136 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Food Insecurity written by William D. Schanbacher and published by Bloomsbury Publishing USA. This book was released on 2023-09-21 with total page 442 pages. Available in PDF, EPUB and Kindle. Book excerpt: This comprehensive and authoritative one-stop resource examines the issue of food insecurity in the United States, including the various economic, social, political, and cultural factors that drive the problem. Social welfare agencies, schools, food banks, and other organizations have all put forth efforts to combat food insecurity, but it remains a serious risk for millions of poor Americans today. Food Insecurity: A Reference Handbook examines the reasons why food insecurity remains such a longstanding problem in American society. Beginning with a history of food insecurity from the country's origins to the present day, the book also delves into the problems and controversies related to food insecurity, such as urban food deserts, substance abuse impacts, nutrition education, and income inequality. One of the most valuable aspects of the book is that it surveys the history of food insecurity in a manner that helps the reader identify key issues in an easy-to-understand fashion. The book's Perspectives chapter presents a broad range of voices on various facets of food insecurity, providing crucial, diverse perspectives to round out the coverage and expertise of the authors.
Download or read book Diabetes During and Beyond Pregnancy A Life Course Perspective written by Wei Bao and published by Frontiers Media SA. This book was released on 2020-08-28 with total page 162 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Ethics in Public Health Practice in India written by Arima Mishra and published by Springer. This book was released on 2018-10-10 with total page 198 pages. Available in PDF, EPUB and Kindle. Book excerpt: This edited volume draws on ten original contributions that locate ethics at the centre-stage of public health practice. The essays explicate ethical issues, challenges, deliberations and resolutions covering a broad canvas of public health practice including policies, programmes, research, training and advocacy. The contributors are academics and practitioners in varying roles and long-standing engagement with public health in diverse settings within India. Their expertise in disciplines range from anthropology, sociology, health communications, gender studies, economics, epidemiology, social work and medicine. Their chapters deal with dimensions of ethical dilemmas that can rarely be defined and contained within ethical guidelines and protocols alone. Instead, they throw light on the associated factors, value systems and contexts in which such complexities occur and require response or redressal. This volume aims to articulate the growing awareness among practitioners that public health ethics is not merely an advanced grouping of possible problems and solutions. It hopes to facilitate robust platforms for dialogue and debate on the subject through the lenses of these contributions. The book is conceptualized to reach broader audiences such as public health practitioners and researchers in several roles within Government health systems, NGOs/Grass root organizations/CSR initiatives/advocacy groups; as well as researchers in academic settings and facilitators involved in teaching ethics and imparting training for students and young practitioners of public health.
Download or read book Viral Gene Therapy written by Ke Xu and published by BoD – Books on Demand. This book was released on 2011-07-20 with total page 466 pages. Available in PDF, EPUB and Kindle. Book excerpt: The development of technologies that allow targeting of specific cells has progressed substantially in recent years for several types of vectors, particularly viral vectors, which have been used in 70% of gene therapy clinical trials. Particular viruses have been selected as gene delivery vehicles because of their capacities to carry foreign genes and their ability to efficiently deliver these genes associated with efficient gene expression. This book is designed to present the most recent advances in viral gene therapy
Download or read book Tandon s Textbook of Cardiology written by Dorairaj Prabhakaran and published by Wolters kluwer india Pvt Ltd. This book was released on 2019-01-17 with total page 1700 pages. Available in PDF, EPUB and Kindle. Book excerpt: An authoritative, comprehensive, and accessible cardiology textbook that caters to the needs of trainees and practicing cardiologists. Cardiovascular disease is now the largest contributor to global mortality. Low and middle income countries. (Lmics) presently bear the brunt of this global epidemic, accounting for over three quarters of cardiovascular deaths and 90% of these deaths under 70 years of age. The experience and expertise of health professionals in these countries will therefore be the principal determinant of global success in countering and curbing the global cardiovascular epidemic in the coming decades. This book covers the fundamentals of cardiology in depth, to provide conceptual clarity, and delves into specific cardiovascular disorders with detailed descriptions that range from aetiology and pathophysiology to evidence informed approaches to diagnosis and management. It does all of this by blending contextual relevance with uncompromising academic rigor.
Download or read book Pandemic Ethics written by Julian Savulescu and published by Oxford University Press. This book was released on 2023-04-01 with total page 413 pages. Available in PDF, EPUB and Kindle. Book excerpt: The COVID-19 pandemic is a defining event of the 21st century. It has taken over eighteen million lives, closed national borders, put whole populations into quarantine and devastated economies. Yet while COVID-19 is catastrophic, it is not unique. Children who have been home-schooled during COVID-19 will almost certainly face another pandemic in their lifetime - one at least as bad-and potentially much worse-than this one. The WHO has referred to such a future (currently unknown) pathogen as “Disease X”. The defining feature of a pandemic is its scale-the simultaneous threat to millions or even billions of lives. That scale leads to unavoidable ethical dilemmas since the lives and livelihood of all cannot be protected. But since one of the most powerful ways of arresting the spread of a pandemic is to reduce contact between people, pandemic ethics also challenges some of our most widely accepted ethical beliefs about individual liberty and autonomy. Finally, pandemic ethics brings vividly to the foreground debates about the structure of society, inequalities, disadvantage and our global responsibilities. In this timely and vital collection, Dominic Wilkinson and Julian Savulescu bring together a global team of leading philosophers, lawyers, economists, and bioethicists. The book reviews the COVID-19 pandemic to ask not only 'did our societies make the right ethical choices?', but also 'what lessons must we learn before Disease X arrives?'
Download or read book The unfolded protein response in virus infections written by Shiu-Wan Chan and published by Frontiers Media SA. This book was released on 2015-03-05 with total page 130 pages. Available in PDF, EPUB and Kindle. Book excerpt: Unfolded protein response (UPR) is a cellular adaptive response for restoring endoplasmic reticulum (ER) homeostasis in response to ER stress. Perturbation of the UPR and failure to restore ER homeostasis inevitably leads to diseases. It has now become evident that perturbation of the UPR is the cause of many important human diseases such as neurodegenerative diseases, cystic fibrosis, diabetes and cancer. It has recently emerged that virus infections can trigger the UPR but the relationship between virus infections and host UPR is intriguing. On one hand, UPR is harmful to the virus and virus has developed means to subvert the UPR. On the other hand, virus exploits the host UPR to assist in its own infection, gene expression, establishment of persistence, reactivation from latency and to evade the immune response. When this delicate balance of virus-host UPR interaction is broken down, it may cause diseases. This is particularly challenging for viruses that establish a chronic infection to maintain this balance. Each virus interacts with the host UPR in a different way to suit their life style and how the virus interacts with the host UPR can define the characteristic of a particular virus infection. Understanding how a particular virus interacts with the host UPR may pave the way to the design of a new class of anti-viral that targets this particular pathway to skew the response towards anti-virus. This knowledge can also be translated into the clinics to help re-design oncolytic virotherapy and gene therapy. In this research topic we aimed to compile a collection of focused review articles, original research articles, commentary, opinion, hypothesis and methods to highlight the current advances in this burgeoning area of research, in an attempt to provide an in-depth understanding of how viruses interact with the host UPR, which may be beneficial to the future combat of viral and human diseases.
