Download or read book Genetics of Apicomplexans and Apicomplexan Related Parasitic Diseases written by Moses Okpeku and published by Frontiers Media SA. This book was released on 2022-03-28 with total page 157 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Apicomplexan Parasites written by Katja Becker and published by John Wiley & Sons. This book was released on 2011-01-19 with total page 548 pages. Available in PDF, EPUB and Kindle. Book excerpt: This handbook is the first dealing with the discovery of drugs directed against apicomplexan parasites. Amongst others, this group of endoparasites includes the causative agents of Malaria, Toxoplasmosis, and Babesiosis, the latter occurring mainly in animals. Written by renowned scientific experts from academia and industry, the book focuses on currentdrug development approaches for all apicomplexan diseases making it appealing to a large audience, ranging from research labs in academia to the human and veterinarian pharmaceutical industry. This work is the second volume of the new book series 'Drug Discovery in Infectious Diseases', edited by Prof. Dr Paul M. Selzer.
Download or read book Handbook of the Protists written by John M. Archibald and published by Springer. This book was released on 2017-08-16 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Published in a modern, user-friendly format this fully revised and updated edition of The Handbook of Protoctista (1990) is the resource for those interested in the biology, diversity and evolution of eukaryotic microorganisms and their descendants, exclusive of animals, plants and fungi. With chapters written by leading researchers in the field, the content reflects the present state of knowledge of the cell and genome biology, evolutionary relationships and ecological/medical/economic importance each major group of protists, organized according to current protist systematics as informed by molecular phylogenetics and genomics.
Download or read book Molecular Basis of Stage Conversion in Apicomplexan Parasites written by Maria E. Francia and published by Frontiers Media SA. This book was released on 2021-06-08 with total page 153 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Toxoplasma Gondii written by Louis M. Weiss and published by Academic Press. This book was released on 2013-08-10 with total page 1109 pages. Available in PDF, EPUB and Kindle. Book excerpt: This 2e of Toxoplasma gondii reflects the significant advances in the field in the last 5 years, including new information on the genomics, epigenomics and proteomics of T. gondii as well as a new understanding of the population biology and genetic diversity of this organism. T. gondii remains the best model system for studying the entire Apicomplexa group of protozoans, which includes Malaria, making this new edition essential for a broad group of researchers and scientists. Toxoplasmosis is caused by a one-celled protozoan parasite known as T. gondii. The infection produces a wide range of clinical syndromes in humans, land and sea mammals, and various bird species. Most humans contract toxoplasmosis by eating contaminated, raw or undercooked meat (particularly pork), vegetables, or milk products; by coming into contact with the T. gondii eggs from cat feces; or by drinking contaminated water. The parasite damages the ocular and central nervous systems, causing behavioral and personality alterations as well as fatal necrotizing encephalitis. It is especially dangerous for the fetus of an infected pregnant woman and for individuals with compromised immune systems, such as HIV-infected patients. Completely updated, the 2e presents recent advances driven by new information on the genetics and genomics of the pathogen Provides the latest information concerning the epidemiology, diagnosis, treatment and prevention of toxoplasmosis Offers a single-source reference for a wide range of scientists and physicians working with this pathogen, including parasitologists, cell and molecular biologists, veterinarians, neuroscientists, physicians, and food scientists
Download or read book Molecular Mechanisms of Parasite Invasion written by Barbara A. Burleigh and published by Springer Science & Business Media. This book was released on 2008-12-05 with total page 255 pages. Available in PDF, EPUB and Kindle. Book excerpt: All of the parasitic organisms highlighted in this new book represent medically important human pathogens that contribute significantly to the global burden of disease. As such there is intense interest in understanding the molecular basis of infection by these pathogens—not only with regard to their clinical relevance but also the fascinating biology they reveal. For most of the parasites discussed here the ability to penetrate biological barriers and/or to establish intracellular residence is critical to survival of the pathogen in the mammalian hosts. For other parasites, a tissue invasive phenotype is a key virulence determinant. In the ensuing 18 chapters, select members of this diverse set of protozoan parasites, as well as some examples of the extremely reduced fungal parasites classified as Microsporidia, are discussed within the context of the fascinating molecular strategies employed by these organisms to migrate across biological barriers and to establish residence within target host cells.
Download or read book Immunization Against East Coast Fever Isolation and Characterization of Theileria Parva Stocks From Unguja and Pemba for Use in Infection and Treatment written by Subhash P. Morzaria and published by ILRI (aka ILCA and ILRAD). This book was released on 1986-01-01 with total page 32 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Toxoplasma Gondii written by Louis M. Weiss and published by Academic Press. This book was released on 2020-02-28 with total page 1244 pages. Available in PDF, EPUB and Kindle. Book excerpt: Toxoplasma gondii: The Model Apicomplexan - Perspectives and Methods, Third Edition, reflects significant advances in the field in the last five years, including new information on the genomics, epigenomics and proteomics of T. gondii, along with a new understanding of the population biology and genetic diversity of this organism. This edition expands information on the effects of T. gondii on human psychiatric disease and new molecular techniques, such as CAS9/CSPR. T gondii remains the best model system for studying the entire Apicomplexa group of protozoans, which includes Malaria, making this new edition essential for a broad group of researchers and scientists. Presents a complete review of molecular and cellar biology and immunology of Toxoplasma gondii combined with methods and resources for working with this pathogen Provides a single source reference for a wide range of scientists and physicians working with this pathogen, including parasitologists, cell and molecular biologists, veterinarians, neuroscientists, physicians and food scientists Covers recent advances in the genomics, related bioinformatics analysis, epigenomics, gene regulation, genetic manipulation and proteomics of T. gondii Details advances in the molecular and cellular biology and immunology of Toxoplasma, and in the epidemiology, diagnosis, treatment and prevention of toxoplasmosis
Download or read book Farm Animals Diseases Recent Omic Trends and New Strategies of Treatment written by Rosa Estela Quiroz Castañeda and published by BoD – Books on Demand. This book was released on 2018-03-21 with total page 200 pages. Available in PDF, EPUB and Kindle. Book excerpt: The scope of this book is to present the most recent trends based on omic analyses of microorganisms causing diseases in farm animals and how these approaches result in new strategies of treatment. The topics in this book include fasciolosis, avian coccidiosis, bovine anaplasmosis, tick-borne diseases, and babesiosis, among others. This book presents the recent advances in the omic field with an emphasis on how these analyses have led researchers to know the mechanisms that pathogens use to invade and colonize the host cell of farm animals. In this way, new treatments of control and prevention can be employed.
Download or read book Diversity of Antigenic Secretion in Apicomplexan Parasites and Its Role in Plasmodium Falciparum Malaria written by KARELL. PELLE and published by . This book was released on 2013 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Apicomplexan parasites are responsible for some of the most devastating human and veterinarian diseases and are parasites of great economic importance. Apicomplexa include Plasmodium, Toxoplasma and Babesia species. The pathogenic mechanisms developed by Apicomplexa parasites, in particular those that reside in a parasitophorous vacuole, involve considerable changes to the host cell, including the expression of variable surface proteins required for immune evasion. In Plasmodium falciparum infections, host cell remodeling is responsible for disease symptomology and severity in the human host. This work represents a multi-faceted study of antigenic secretion and the role of secreted antigens in pathogenesis. We study in detail the mechanisms of antigen secretion in Apicomplexa parasites. By use of comparative genomics, we find Plasmodium Export Element (PEXEL)-like motifs in a subset of Cryptosporidium and Babesia secreted proteins. However, in Babesia the motif functions as a spherical body targeting sequence, suggesting that secretory mechanisms in Apicomplexa are adapted to the parasite's intracellular lifestyle. To elucidate the relationship and function of exported antigens, we first focused on P. falciparum to determine gene co-expression modules. We found that in vivo, export modules are composed of constitutively or variably expressed genes, the latter group associated with patient clinical phenotypes. We then focused on a novel gene family called "phist" and show, using transcriptional expression profiling, its role in P. falciparum cytoadherence. In total, we demonstrate that antigen secretion is an evolutionary mechanism in Apicomplexa parasites and that variant expression of the genes encoding these antigens may allow parasites to adapt to environmental stresses.
Download or read book Secondary Endosymbioses written by Yoshihisa Hirakawa and published by Academic Press. This book was released on 2017-10-27 with total page 452 pages. Available in PDF, EPUB and Kindle. Book excerpt: Secondary Endosymbioses, Volume 84, the latest release in the Advances in Botanical Research series, summarizes eight major groups possessing complex plastids, including heterokonts, dinoflagellates, apicomplexans, chromerids, haptophytes, cryptophytes, euglenophytes and chlorarachniophytes. Updates to this new volume include sections on the Evolution of secondary plastid-bearing organisms, Primary plastids of Archeaplastida, Secondary plastids of heterokonts (diatoms), Secondary and tertiary plastids of dinoflagellates, Apicoplasts, Secondary plastids of chromerids, Secondary Plastids of haptophytes, Secondary Plastids of cryptophytes, Secondary Plastids of euglenids, and Secondary Plastids of chlorarachinophytes. Through an examination on how plastids evolved by multiple endosymbiotic events, this book discusses how diverse and abundant organisms harbor complex plastids. Presents the latest release in the Advances in Botanical Research series Ideal resource for post-graduates and researchers in the plant sciences, including botany, plant biochemistry, plant pathology and plant physiology Contains contributions from internationally recognized authorities in their respective fields
Download or read book The Biology and Identification of the Coccidia Apicomplexa of Marsupials of the World written by Donald W. Duszynski and published by Academic Press. This book was released on 2015-09-10 with total page 256 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Biology and Identification of the Coccidia (Apicomplexa) of Marsupials of the World contains the most up-to-date information on the former order marsupial that is now partitioned by mammalogists into seven separate orders that contain 20 families, 86 genera, and 318 species that live on land or in trees in Oceania and the Americas. Marsupials, like other vertebrate animals have many different kinds of parasites (e.g. viruses, protozoa, worms, arthropods, etc.), but there is no definitive text that covers any one of these groups found in all marsupials. Coccidiosis is a serious global problem in most domesticated animals, and under increasing circumstances of loss of habitat and crowding, may also affect some wild animal populations, thus, there is a real need for their identification and control. Offers line drawings and photomicrograph of each parasite from each hosts species, including methods of identification and treatment Presents a complete historical rendition of all known publications on coccidia (and their closest relatives) from all marsupials species on Earth, and evaluates the scientific and scholarly merit of each Provides a complete species analysis of the known biology of every coccidian described from marsupials Reviews the most current taxonomy of marsupials and their phylogenetic relationships needed to help assess host-specificity and evaluate what little cross-transmission work is available
Download or read book Parasitic Protozoa of Farm Animals and Pets written by Monica Florin-Christensen and published by Springer. This book was released on 2018-04-17 with total page 438 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book provides an in-depth yet concise overview of the most common and emerging protozoa that cause diseases in both farm animals and companion animals. As outlined in the concise introduction, pathogenic protozoans represent an evolutionary highly diverse and little understood group of disease-causing microorganisms. For each of the featured parasitic unicellular eukaryotes, it discusses the morphology, lifecycle, epidemiology and host-pathogen interactions. In addition, the book highlights the latest developments in diagnostic methods, as well as prevention and treatment strategies. Thorough information on genomes and genetic manipulation strategies for some of the protozoa covered in this book is also included. Infections involving parasitic protozoa can cause productivity losses and/or reduce the quality of life of infected animals. Some infections are zoonotic, posing an on-going public health threat. In most cases, prevention and treatment are either non-existent or need considerable improvement. On the other hand, a great deal of research has recently been conducted on these organisms, yielding valuable new information on their global distribution and revealing the mechanisms of host-pathogen interactions at the molecular level – and essential insights that can be used for the development of new control tools. This book includes extensive information on both basic aspects and recent scientific discoveries on these protozoa and thus constitutes a unique resource for students, veterinarians, and researchers alike.
Download or read book Comprehensive Biophysics written by and published by Academic Press. This book was released on 2012-04-12 with total page 3533 pages. Available in PDF, EPUB and Kindle. Book excerpt: Biophysics is a rapidly-evolving interdisciplinary science that applies theories and methods of the physical sciences to questions of biology. Biophysics encompasses many disciplines, including physics, chemistry, mathematics, biology, biochemistry, medicine, pharmacology, physiology, and neuroscience, and it is essential that scientists working in these varied fields are able to understand each other's research. Comprehensive Biophysics, Nine Volume Set will help bridge that communication gap. Written by a team of researchers at the forefront of their respective fields, under the guidance of Chief Editor Edward Egelman, Comprehensive Biophysics, Nine Volume Set provides definitive introductions to a broad array of topics, uniting different areas of biophysics research - from the physical techniques for studying macromolecular structure to protein folding, muscle and molecular motors, cell biophysics, bioenergetics and more. The result is this comprehensive scientific resource - a valuable tool both for helping researchers come to grips quickly with material from related biophysics fields outside their areas of expertise, and for reinforcing their existing knowledge. Biophysical research today encompasses many areas of biology. These studies do not necessarily share a unique identifying factor. This work unites the different areas of research and allows users, regardless of their background, to navigate through the most essential concepts with ease, saving them time and vastly improving their understanding The field of biophysics counts several journals that are directly and indirectly concerned with the field. There is no reference work that encompasses the entire field and unites the different areas of research through deep foundational reviews. Comprehensive Biophysics fills this vacuum, being a definitive work on biophysics. It will help users apply context to the diverse journal literature offering, and aid them in identifying areas for further research Chief Editor Edward Egelman (E-I-C, Biophysical Journal) has assembled an impressive, world-class team of Volume Editors and Contributing Authors. Each chapter has been painstakingly reviewed and checked for consistent high quality. The result is an authoritative overview which ties the literature together and provides the user with a reliable background information and citation resource
Download or read book Structures and Organelles in Pathogenic Protists written by W. de Souza and published by Springer Science & Business Media. This book was released on 2010-09-10 with total page 332 pages. Available in PDF, EPUB and Kindle. Book excerpt: Parasitic protozoa, including some which are agents of human and veterinary diseases, display special cytoplasmic structures and organelles. Metabolic pathways have been discovered in these organelles which open up new possibilities for drug targets. This work presents reviews dealing with cytoskeletal structures such as the mastigont system found in trichomonads, the sub-pellicular microtubules in trypanosomatids and the paraflagellar rod. Further chapters cover structures involved in the synthesis, secretion and uptake of molecules, including the flagellar pocket of trypanosomatids, the reservosome of Trypanosoma and the megasome found in Leishmania, the traffic of vesicles in Entamoeba histolytica, secretory organelles and the secretory events of intestinal parasites during encystation. Reviews on special organelles, such as the kinetoplast-mitochondrion complex, the apicoplast found in Apicomplexa, the glycosomes in Kinetoplastida and the acidocalcisomes found in several protozoa complete the volume.
Download or read book Encyclopedia of Parasitology A M written by Heinz Mehlhorn and published by Springer Science & Business Media. This book was released on 2007-11-28 with total page 1577 pages. Available in PDF, EPUB and Kindle. Book excerpt: Knowledge in the field of parasitology must be kept at a high level and up to date in order to fight a parasitosis as quickly and effectively as possible. The third edition of this, one of Springer’s renowned and authoritative Major Reference Works, contributes to these goals in several ways. First, the number of entries has been increased by about 30%. Secondly the content has been improved even more by adding additional tables and figures. Thirdly, the extensive linking between definitions and essays facilitates information within a minimum of time. More than 40 international contributors, who are well known specialists in their fields, give a comprehensive review of all parasites and therapeutic strategies in veterinarian and human parasitology.
Download or read book The Biology and Identification of the Coccidia Apicomplexa of Carnivores of the World written by Donald W. Duszynski and published by Academic Press. This book was released on 2018-06-29 with total page 315 pages. Available in PDF, EPUB and Kindle. Book excerpt: The fundamental concept of The Biology and Identification of the Coccidia (Apicomplexa) of Carnivores of the World is to provide an up-to-date reference guide to the identification, taxonomy, and known biology of apicomplexan intestinal and tissue parasites of carnivores including, but not limited to, geographic distribution, prevalence, sporulation, prepatent and patent periods, site(s) of infection in the definitive and (if known) intermediate hosts, endogenous development, cross-transmission, pathology, phylogeny, and (if known) their treatments. These data will allow easy parasite recognition with a summation of virtually everything now known about the biology of each parasite species covered. The last (very modest) and only treatise published on this subject was in 1981 so this book fills a fundamental gap in our knowledge of what is now known, and what is not, about the coccidian parasites that infect and sometimes kill carnivores and/or their prey that can harbor intermediate stages, including many domestic and game animals. Offers line drawings and photomicrographs of many parasite species that will allow easy diagnosis and identification by both laypersons and professionals (veterinarians, wildlife biologists, etc.) Presents a complete historical rendition of all known publications on carnivore coccidia for all carnivore families and evaluates the scientific and scholarly merit of each apicomplexan species relative to the current body of knowledge Provides a complete species analysis and their known biology of all coccidia described from each carnivore lineage and species Reviews the most current taxonomy of carnivores and their phylogenetic relationships to help assess host-specificity patterns that may be apparent Evaluates what little cross-transmission work is available to help understand the complexities of those coccidians that use two hosts (e.g., Sarcocystis, Besnoitia, and others) Provides known treatments for the various parasite genera/species
