Download or read book Genetics in the Madhouse written by Theodore M. Porter and published by Princeton University Press. This book was released on 2020-07-14 with total page 462 pages. Available in PDF, EPUB and Kindle. Book excerpt: "In the early 1800s, a century before there was any concept of the gene, physicians in insane asylums began to record causes of madness in their admission books. Almost from the beginning, they pointed to heredity as the most important of these causes. As doctors and state officials steadily lost faith in the capacity of asylum care to stem the terrible increase of insanity, they began emphasizing the need to curb the reproduction of the insane. They became obsessed with identifying weak or tainted families and anticipating the outcomes of their marriages. Genetics in the Madhouse is the untold story of how the collection and sorting of hereditary data in mental hospitals, schools for 'feebleminded' children, and prisons gave rise to a new science of human heredity. In this compelling book, Theodore Porter draws on untapped archival evidence from across Europe and North America to bring to light the hidden history behind modern genetics. He looks at the institutional use of pedigree charts, censuses of mental illness, medical-social surveys, and other data techniques--innovative quantitative practices that were worked out in the madhouse long before the manipulation of DNA became possible in the lab. Porter argues that asylum doctors developed many of the ideologies and methods of what would come to be known as eugenics, and deepens our appreciation of the moral issues at stake in data work conducted on the border of subjectivity and science. A bold rethinking of asylum work, Genetics in the Madhouse shows how heredity was a human science as well as a medical and biological one"--Jacket.
Download or read book She Has Her Mother s Laugh written by Carl Zimmer and published by Penguin. This book was released on 2018-05-29 with total page 672 pages. Available in PDF, EPUB and Kindle. Book excerpt: 2019 PEN/E.O. Wilson Literary Science Writing Award Finalist "Science book of the year"—The Guardian One of New York Times 100 Notable Books for 2018 One of Publishers Weekly's Top Ten Books of 2018 One of Kirkus's Best Books of 2018 One of Mental Floss's Best Books of 2018 One of Science Friday's Best Science Books of 2018 “Extraordinary”—New York Times Book Review "Magisterial"—The Atlantic "Engrossing"—Wired "Leading contender as the most outstanding nonfiction work of the year"—Minneapolis Star-Tribune Celebrated New York Times columnist and science writer Carl Zimmer presents a profoundly original perspective on what we pass along from generation to generation. Charles Darwin played a crucial part in turning heredity into a scientific question, and yet he failed spectacularly to answer it. The birth of genetics in the early 1900s seemed to do precisely that. Gradually, people translated their old notions about heredity into a language of genes. As the technology for studying genes became cheaper, millions of people ordered genetic tests to link themselves to missing parents, to distant ancestors, to ethnic identities... But, Zimmer writes, “Each of us carries an amalgam of fragments of DNA, stitched together from some of our many ancestors. Each piece has its own ancestry, traveling a different path back through human history. A particular fragment may sometimes be cause for worry, but most of our DNA influences who we are—our appearance, our height, our penchants—in inconceivably subtle ways.” Heredity isn’t just about genes that pass from parent to child. Heredity continues within our own bodies, as a single cell gives rise to trillions of cells that make up our bodies. We say we inherit genes from our ancestors—using a word that once referred to kingdoms and estates—but we inherit other things that matter as much or more to our lives, from microbes to technologies we use to make life more comfortable. We need a new definition of what heredity is and, through Carl Zimmer’s lucid exposition and storytelling, this resounding tour de force delivers it. Weaving historical and current scientific research, his own experience with his two daughters, and the kind of original reporting expected of one of the world’s best science journalists, Zimmer ultimately unpacks urgent bioethical quandaries arising from new biomedical technologies, but also long-standing presumptions about who we really are and what we can pass on to future generations.
Download or read book Genetics in the Madhouse written by Theodore M. Porter and published by Princeton University Press. This book was released on 2018-06-05 with total page 463 pages. Available in PDF, EPUB and Kindle. Book excerpt: The untold story of how hereditary data in mental hospitals gave rise to the science of human heredity In the early 1800s, a century before there was any concept of the gene, physicians in insane asylums began to record causes of madness in their admission books. Almost from the beginning, they pointed to heredity as the most important of these causes. As doctors and state officials steadily lost faith in the capacity of asylum care to stem the terrible increase of insanity, they began emphasizing the need to curb the reproduction of the insane. They became obsessed with identifying weak or tainted families and anticipating the outcomes of their marriages. Genetics in the Madhouse is the untold story of how the collection and sorting of hereditary data in mental hospitals, schools for "feebleminded" children, and prisons gave rise to a new science of human heredity. In this compelling book, Theodore Porter draws on untapped archival evidence from across Europe and North America to bring to light the hidden history behind modern genetics. He looks at the institutional use of pedigree charts, censuses of mental illness, medical-social surveys, and other data techniques--innovative quantitative practices that were worked out in the madhouse long before the manipulation of DNA became possible in the lab. Porter argues that asylum doctors developed many of the ideologies and methods of what would come to be known as eugenics, and deepens our appreciation of the moral issues at stake in data work conducted on the border of subjectivity and science. A bold rethinking of asylum work, Genetics in the Madhouse shows how heredity was a human science as well as a medical and biological one.
Download or read book Trust in Numbers written by Theodore M. Porter and published by Princeton University Press. This book was released on 2020-08-18 with total page 336 pages. Available in PDF, EPUB and Kindle. Book excerpt: A foundational work on historical and social studies of quantification What accounts for the prestige of quantitative methods? The usual answer is that quantification is desirable in social investigation as a result of its successes in science. Trust in Numbers questions whether such success in the study of stars, molecules, or cells should be an attractive model for research on human societies, and examines why the natural sciences are highly quantitative in the first place. Theodore Porter argues that a better understanding of the attractions of quantification in business, government, and social research brings a fresh perspective to its role in psychology, physics, and medicine. Quantitative rigor is not inherent in science but arises from political and social pressures, and objectivity derives its impetus from cultural contexts. In a new preface, the author sheds light on the current infatuation with quantitative methods, particularly at the intersection of science and bureaucracy.
Download or read book The Epigenetics Revolution written by Nessa Carey and published by Columbia University Press. This book was released on 2012-03-06 with total page 353 pages. Available in PDF, EPUB and Kindle. Book excerpt: Epigenetics can potentially revolutionize our understanding of the structure and behavior of biological life on Earth. It explains why mapping an organism's genetic code is not enough to determine how it develops or acts and shows how nurture combines with nature to engineer biological diversity. Surveying the twenty-year history of the field while also highlighting its latest findings and innovations, this volume provides a readily understandable introduction to the foundations of epigenetics. Nessa Carey, a leading epigenetics researcher, connects the field's arguments to such diverse phenomena as how ants and queen bees control their colonies; why tortoiseshell cats are always female; why some plants need cold weather before they can flower; and how our bodies age and develop disease. Reaching beyond biology, epigenetics now informs work on drug addiction, the long-term effects of famine, and the physical and psychological consequences of childhood trauma. Carey concludes with a discussion of the future directions for this research and its ability to improve human health and well-being.
Download or read book The Rise of Statistical Thinking 1820 1900 written by Theodore M. Porter and published by Princeton University Press. This book was released on 2020-08-18 with total page 360 pages. Available in PDF, EPUB and Kindle. Book excerpt: An essential work on the origins of statistics The Rise of Statistical Thinking, 1820–1900 explores the history of statistics from the field's origins in the nineteenth century through to the factors that produced the burst of modern statistical innovation in the early twentieth century. Theodore Porter shows that statistics was not developed by mathematicians and then applied to the sciences and social sciences. Rather, the field came into being through the efforts of social scientists, who saw a need for statistical tools in their examination of society. Pioneering statistical physicists and biologists James Clerk Maxwell, Ludwig Boltzmann, and Francis Galton introduced statistical models to the sciences by pointing to analogies between their disciplines and the social sciences. A new preface by the author looks at how the book has remained relevant since its initial publication, and considers the current place of statistics in scientific research.
Download or read book Karl Pearson written by Theodore M. Porter and published by Princeton University Press. This book was released on 2010-01-02 with total page 353 pages. Available in PDF, EPUB and Kindle. Book excerpt: Karl Pearson, founder of modern statistics, came to this field by way of passionate early studies of philosophy and cultural history as well as ether physics and graphical geometry. His faith in science grew out of a deeply moral quest, reflected also in his socialism and his efforts to find a new basis for relations between men and women. This biography recounts Pearson's extraordinary intellectual adventure and sheds new light on the inner life of science. Theodore Porter's intensely personal portrait of Pearson extends from religious crisis and sexual tensions to metaphysical and even mathematical anxieties. Pearson sought to reconcile reason with enthusiasm and to achieve the impersonal perspective of science without sacrificing complex individuality. Even as he longed to experience nature directly and intimately, he identified science with renunciation and positivistic detachment. Porter finds a turning point in Pearson's career, where his humanistic interests gave way to statistical ones, in his Grammar of Science (1892), in which he attempted to establish scientific method as the moral educational basis for a refashioned culture. In this original and engaging book, a leading historian of modern science investigates the interior experience of one man's scientific life while placing it in a rich tapestry of social, political, and intellectual movements.
Download or read book Desperate Remedies written by Andrew Scull and published by Harvard University Press. This book was released on 2022-05-17 with total page 513 pages. Available in PDF, EPUB and Kindle. Book excerpt: A Telegraph Book of the Year A Washington Post Notable Work A Times Book of the Year A Hughes Award Finalist “An indisputable masterpiece...comprehensive, fascinating, and persuasive.” —Wall Street Journal “Brimming with wisdom and brio, this masterful work spans the history of psychiatry. Exceedingly well-researched, wide-ranging, provocative in its conclusions, and magically compact, it is riveting from start to finish. Mark my words, Desperate Remedies will soon be a classic.” —Susannah Cahalan, author of Brain on Fire “Compulsively readable...Scull has joined his wide-ranging reporting and research with a humane perspective on matters that many of us continue to look away from.” —Daphne Merkin, The Atlantic "Scull's fascinating and enraging book is the story of the quacks and opportunists who have claimed to offer cures for mental illness...Madness remains the most fascinating—arguably the defining—aspect of Homo sapiens." —Sebastian Faulks, Sunday Times “I would recommend this fascinating, alarming, and alerting book to anybody. For anyone referred to a psychiatrist it is surely essential.” —The Spectator For more than two hundred years disturbances of the mind have been studied and treated by the medical profession. Mental illness, some insist, is a disease like any other, from which one can be cured. But is this true? From the birth of the asylum to the latest drug trials, Desperate Remedies brings together a galaxy of mind doctors working in and out of institutional settings: psychologists and psychoanalysts, neuroscientists and cognitive behavioral therapists, as well as patients and their families desperate for relief. Surprising, disturbing, and compelling, this passionate account of America’s long battle with mental illness challenges us to revisit some of our deepest assumptions and to confront the epidemic of mental illness so visible all around us.
Download or read book A Cultural History of Heredity written by Staffan Müller-Wille and published by University of Chicago Press. This book was released on 2012-06-26 with total page 339 pages. Available in PDF, EPUB and Kindle. Book excerpt: Heredity: knowledge and power -- Generation, reproduction, evolution -- Heredity in separate domains -- First syntheses -- Heredity, race, and eugenics -- Disciplining heredity -- Heredity and molecular biology -- Gene technology, genomics, postgenomics: attempt at an outlook.
Download or read book Genome Chaos written by Henry H. Heng and published by Academic Press. This book was released on 2019-05-25 with total page 564 pages. Available in PDF, EPUB and Kindle. Book excerpt: Genome Chaos: Rethinking Genetics, Evolution, and Molecular Medicine transports readers from Mendelian Genetics to 4D-genomics, building a case for genes and genomes as distinct biological entities, and positing that the genome, rather than individual genes, defines system inheritance and represents a clear unit of selection for macro-evolution. In authoring this thought-provoking text, Dr. Heng invigorates fresh discussions in genome theory and helps readers reevaluate their current understanding of human genetics, evolution, and new pathways for advancing molecular and precision medicine. - Bridges basic research and clinical application and provides a foundation for re-examining the results of large-scale omics studies and advancing molecular medicine - Gathers the most pressing questions in genomic and cytogenomic research - Offers alternative explanations to timely puzzles in the field - Contains eight evidence-based chapters that discuss 4d-genomics, genes and genomes as distinct biological entities, genome chaos and macro-cellular evolution, evolutionary cytogenetics and cancer, chromosomal coding and fuzzy inheritance, and more
Download or read book Poached written by Rachel Love Nuwer and published by Da Capo Press. This book was released on 2018-09-25 with total page 471 pages. Available in PDF, EPUB and Kindle. Book excerpt: An intrepid investigation of the criminal world of wildlife trafficking--the poachers, the traders, and the customers--and of those fighting against it Journalist Rachel Nuwer plunges the reader into the underground of global wildlife trafficking, a topic she has been investigating for nearly a decade. Our insatiable demand for animals -- for jewelry, pets, medicine, meat, trophies, and fur -- is driving a worldwide poaching epidemic, threatening the continued existence of countless species. Illegal wildlife trade now ranks among the largest contraband industries in the world, yet compared to drug, arms, or human trafficking, the wildlife crisis has received scant attention and support, leaving it up to passionate individuals fighting on the ground to try to ensure that elephants, tigers, rhinos, and more are still around for future generations. As Reefer Madness (Schlosser) took us into the drug market, or Susan Orlean descended into the swampy obsessions of TheOrchid Thief, Nuwer--an award-winning science journalist with a background in ecology--takes readers on a narrative journey to the front lines of the trade: to killing fields in Africa, traditional medicine black markets in China, and wild meat restaurants in Vietnam. Through exhaustive first-hand reporting that took her to ten countries, Nuwer explores the forces currently driving demand for animals and their parts; the toll that demand is extracting on species across the planet; and the conservationists, rangers, and activists who believe it is not too late to stop the impending extinctions. More than a depressing list of statistics, Poached is the story of the people who believe this is a battle that can be won, that our animals are not beyond salvation.
Download or read book Madness in Civilization written by Andrew Scull and published by Princeton University Press. This book was released on 2015-04-06 with total page 12 pages. Available in PDF, EPUB and Kindle. Book excerpt: Originally published: London: Thames & Hudson Ltd, 2015.
Download or read book Medical History Education for Health Practitioners written by Lisett Lovett and published by CRC Press. This book was released on 2022-02-16 with total page 259 pages. Available in PDF, EPUB and Kindle. Book excerpt: 'Twenty-first century medicine is just the current stage of a never-ending journey of tremendous complexity. Those of us who are fortunate enough to practise in this day and age do so in ways that are themselves the results of huge changes over many centuries - advances in areas such as medication and surgical and imaging techniques and developments in our understanding of the human body and its attendant threats through genetics. Add to that list the huge social and societal changes in public health, attitudes to illness and changes in ethical viewpoints, and we find ourselves at the current forefront of medical evolution but nowhere near the end of this particular journey.' From the Foreword by Paul Lazarus This fascinating book brings to life the history of medicine in Britain since 1600. Throughout the historical account the authors cover mainstream clinical issues but also make reference to the importance of literature and art, presenting a wide-ranging view of the past. It also incorporates milestones in other cultures and epochs, where appropriate, for a balanced overview. The concise, self-contained sections are a joy to read and can be easily dipped into. The majority of chapters include suggested questions for students, assisting group discussion. It is ideal for medical and healthcare course organisers, lecturers and tutors who require a rapid resource of information in their subject area - be it cardiovascular disease, emergency medicine or child protection - to provide context, interest and entertainment for their students. It is also highly recommended as the basis for a programme of seminars on the history of medicine.
Download or read book Human Genetics written by Ricki Lewis and published by McGraw-Hill Science, Engineering & Mathematics. This book was released on 2004-02 with total page 439 pages. Available in PDF, EPUB and Kindle. Book excerpt: Human Genetics, 6/e is a non-science majors human genetics text that clearly explains what genes are, how they function, how they interact with the environment, and how our understanding of genetics has changed since completion of the human genome project. It is a clear, modern, and exciting book for citizens who will be responsible for evaluating new medical options, new foods, and new technologies in the age of genomics.
Download or read book Give a Girl a Knife written by Amy Thielen and published by Clarkson Potter Publishers. This book was released on 2017 with total page 322 pages. Available in PDF, EPUB and Kindle. Book excerpt: Amy Thielen, author of the James Beard Award-winning cookbook The New Midwestern Table, traces her journey from Park Rapids, Minnesota, to cooking professionally under some of New York City's finest chefs -- including David Bouley, Daniel Boulud, and Jean-Georges Vongerichten -- and then back home again. A love of food and an overwhelming desire to get the hell out of small-town America drive Thielen to New York to seek out its intense culinary world, which she embraces enthusiastically, while her boyfriend finds success in its fickle art world. After years of living in the city, with frequent trips back home in the summertime, the couple eventually chooses life deep in the woods in a cabin Thielen's husband built by hand. There Aaron can practice his craft while Amy takes the skills she learned cooking professionally and turns them to undoing years of processed foods to uncover true Midwestern cooking, which begins simply with humble workhorse ingredients such as potatoes and onions.
Download or read book At the Mountains of Madness written by H. P. Lovecraft and published by DigiCat. This book was released on 2022-11-13 with total page 140 pages. Available in PDF, EPUB and Kindle. Book excerpt: At the Mountains of Madness is a story, which details the events of a disastrous expedition to the Antarctic continent in September 1930 and what was found there by a group of explorers led by the narrator, Dr. William Dyer of Miskatonic University. Throughout the story, Dyer details a series of previously untold events in the hope of deterring another group of explorers who wish to return to the continent. The title is derived from a line in "The Hashish Man," a short story by fantasy writer Edward Plunkett, Lord Dunsany: "And we came at last to those ivory hills that are named the Mountains of Madness..." Howard Phillips Lovecraft (1890-1937) was an American author who achieved posthumous fame through his influential works of horror fiction. He is now regarded as one of the most significant 20th-century authors in his genre. Some of Lovecraft's work was inspired by his own nightmares. His interest started from his childhood days when his grandfather would tell him Gothic horror stories.
Download or read book Data Journeys in the Sciences written by Sabina Leonelli and published by Springer Nature. This book was released on 2020-06-29 with total page 411 pages. Available in PDF, EPUB and Kindle. Book excerpt: This groundbreaking, open access volume analyses and compares data practices across several fields through the analysis of specific cases of data journeys. It brings together leading scholars in the philosophy, history and social studies of science to achieve two goals: tracking the travel of data across different spaces, times and domains of research practice; and documenting how such journeys affect the use of data as evidence and the knowledge being produced. The volume captures the opportunities, challenges and concerns involved in making data move from the sites in which they are originally produced to sites where they can be integrated with other data, analysed and re-used for a variety of purposes. The in-depth study of data journeys provides the necessary ground to examine disciplinary, geographical and historical differences and similarities in data management, processing and interpretation, thus identifying the key conditions of possibility for the widespread data sharing associated with Big and Open Data. The chapters are ordered in sections that broadly correspond to different stages of the journeys of data, from their generation to the legitimisation of their use for specific purposes. Additionally, the preface to the volume provides a variety of alternative “roadmaps” aimed to serve the different interests and entry points of readers; and the introduction provides a substantive overview of what data journeys can teach about the methods and epistemology of research.
