Download or read book Genetics in Asthma and Allergy written by Deborah A. Meyers and published by W B Saunders Company. This book was released on 2005 with total page 10 pages. Available in PDF, EPUB and Kindle. Book excerpt: Significant progress has been made in understanding the pathogenesis of many allergic disorders. In spite of the tremendous complexity, dramatic progress in the past few years has led to an improved understanding of the genetic contributions to allergic and immunoregulatory disorders. This issue is divided into four parts: reviews of positional cloned genes from family studies, gene-environment interactions, gene-by-gene interactions, and future directions.
Download or read book Finding a Path to Safety in Food Allergy written by National Academies of Sciences, Engineering, and Medicine and published by National Academies Press. This book was released on 2017-05-27 with total page 575 pages. Available in PDF, EPUB and Kindle. Book excerpt: Over the past 20 years, public concerns have grown in response to the apparent rising prevalence of food allergy and related atopic conditions, such as eczema. Although evidence on the true prevalence of food allergy is complicated by insufficient or inconsistent data and studies with variable methodologies, many health care experts who care for patients agree that a real increase in food allergy has occurred and that it is unlikely to be due simply to an increase in awareness and better tools for diagnosis. Many stakeholders are concerned about these increases, including the general public, policy makers, regulatory agencies, the food industry, scientists, clinicians, and especially families of children and young people suffering from food allergy. At the present time, however, despite a mounting body of data on the prevalence, health consequences, and associated costs of food allergy, this chronic disease has not garnered the level of societal attention that it warrants. Moreover, for patients and families at risk, recommendations and guidelines have not been clear about preventing exposure or the onset of reactions or for managing this disease. Finding a Path to Safety in Food Allergy examines critical issues related to food allergy, including the prevalence and severity of food allergy and its impact on affected individuals, families, and communities; and current understanding of food allergy as a disease, and in diagnostics, treatments, prevention, and public policy. This report seeks to: clarify the nature of the disease, its causes, and its current management; highlight gaps in knowledge; encourage the implementation of management tools at many levels and among many stakeholders; and delineate a roadmap to safety for those who have, or are at risk of developing, food allergy, as well as for others in society who are responsible for public health.
Download or read book Heterogeneity in Asthma written by Allan R. Brasier and published by Springer Science & Business Media. This book was released on 2014-07-08 with total page 353 pages. Available in PDF, EPUB and Kindle. Book excerpt: Asthma is a chronic relapsing airways disease that represents a major public health problem worldwide. Intermittent exacerbations are provoked by airway mucosal exposure to pro-inflammatory stimuli, with RNA viral infections or inhaled allergens representing the two most common precipitants. In this setting, inducible signaling pathways the airway mucosa play a central role in the initiation of airway inflammation through production of antimicrobial peptides (defensins), cytokines, chemokines and arachidonic acid metabolites that coordinate the complex processes of vascular permeability, cellular recruitment, mucous hyper-secretion, bronchial constriction and tissue remodeling. These signals also are responsible for leukocytic infiltration into the submucosa, T helper-lymphocyte skewing, and allergic sensitization. Currently, it is well appreciated that asthma is a heterogeneous in terms of onset, exacerbants, severity, and treatment response. Current asthma classification methods are largely descriptive and focus on a single aspect or dimension of the disease. An active area of investigation on how to collect, use and visualize multidimensional profiling in asthma. This book will overview multidimensional profiling strategies and visualization approaches for phenotyping asthma. As an outcome, this work will facilitate the understanding of disease etiology, prognosis and/or therapeutic intervention.
Download or read book The Hereditary Basis of Allergic Diseases written by Stephen T. Holgate and published by Birkhäuser. This book was released on 2012-12-06 with total page 204 pages. Available in PDF, EPUB and Kindle. Book excerpt: Allergic diseases are complex and involve a range of environmental factors interacting with a susceptible genotype. The familial clustering of diseases, such as asthma and hay fever, has been recognised for over two centuries, but identification of the genetic basis to this had to await the molecular biological revolution. Estimates of the contribution that genetic factors make to asthma susceptibility range from 35% to 70%. For the majority of allergic diseases, segregation analysis has not identified a consistent Mendelian pattern of inheritance, which, when combined with multiple phenotypes and environmental interactions, has made identifying candidate genes especially difficult and, at times, controversial. Part of the difficulty has been lack of agreement over phenotype definitions, reduced power of studies to predict linkage and association, and, importantly, lack of true heterogeneity between populations. Despite these difficulties, the last decade has witnessed enormous progress in this field.
Download or read book Genetics of Allergy and Asthma written by Malcolm N. Blumenthal and published by CRC Press. This book was released on 1997-01-02 with total page 384 pages. Available in PDF, EPUB and Kindle. Book excerpt: Extends investigative studies of allergic disease pathogenesis through a biological and environmental interaction approach-from historical grounding to genetic-nongenetic allergen identification in asthma and allergy development.
Download or read book Allergy and Allergic Diseases written by A. Barry Kay and published by Wiley-Blackwell. This book was released on 1997-07-14 with total page 1872 pages. Available in PDF, EPUB and Kindle. Book excerpt: The most comprehensive and up-to-date allergy textbook in the world. Over 100 chapters written by world leading authorities covering virtually every aspect of basic and clinical allergy fully illustrated throughout with numerous overview diagrams and many colour illustrations. Authors contributing are from UK, Europe, North America and Australia.
Download or read book Asthma written by Celso Pereira and published by BoD – Books on Demand. This book was released on 2016-07-06 with total page 256 pages. Available in PDF, EPUB and Kindle. Book excerpt: The clinical specificities developed in this book, particularly from those reported in the pediatric population to those reported in complex shapes at ACOS patients, emphasize the importance of identifying not only biomarkers but also critical aspects regarding the variability in pharmacogenomics responsible for the individual response to the different drugs on the therapeutic plan. The contribution of several well-known specialists with their profound knowledge inherent to this issue into different age groups and socio geographical contexts has resulted in this interesting book with relevant key contents in asthma.
Download or read book Janeway s Immunobiology written by Kenneth Murphy and published by Garland Science. This book was released on 2010-06-22 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt: The Janeway's Immunobiology CD-ROM, Immunobiology Interactive, is included with each book, and can be purchased separately. It contains animations and videos with voiceover narration, as well as the figures from the text for presentation purposes.
Download or read book Advances in Asthma written by Akihito Yokoyama and published by Springer. This book was released on 2018-12-18 with total page 189 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book provides discussions on bronchial asthma from a clinical perspective, focusing on the recent studies on its pathophysiology, diagnosis and treatment. It also explores the lastest findings regarding the phenotypes and endotypes of asthmatic patients, making it of particular interest to those involved with non-eosinophilic asthma and eosinophilic asthma. Further, it discusses the importance of ILC 2 in eosinophilic asthma, and the accumulated results from the forced oscilliation technique and periostin that are actively practiced in Japan. As some aspects of diagnosis and treatment are different in Western and Asian countries, it is important that the data is disseminated around the globe. The clinical questions addressed by the authors are critical and thought provoking, while the questions raised by the editors are instructive, informative and provide new perspectives on unresolved issues. This book appeals to wide readership from beginning learners to physicians in clinical practice and scholars engaging in basic research.
Download or read book Allergic Diseases From Basic Mechanisms to Comprehensive Management and Prevention written by Claudia Traidl-Hoffmann and published by Springer Nature. This book was released on 2021-11-21 with total page 489 pages. Available in PDF, EPUB and Kindle. Book excerpt: Allergy is the most frequent chronic disease in the 21st century having severe negative effects on health and the economy. The challenge we therefore face in medicine and science incorporates all areas of society – from politics to food industry, from schools to city planning, and many more. This volume informs the reader about continuously ongoing developments in allergy research and their implications for society. The chapter sections cover the immunological mechanisms in allergy on a molecular level, describe the triggers and cures for allergy in detail, entail clinical translation of lab findings on allergens, evaluate diagnostics for allergy markers, and provide solutions for future medical intervention or preventive strategies. Laboratory research, bioinformatics, climate modelling, patient treatment, intervention studies, epigenetics and multiple other disciplines are able to shed new light on this revolutionary field of healthcare.
Download or read book Exhaled Biomarkers written by I. Horvath and published by European Respiratory Society. This book was released on 2010-09-01 with total page 261 pages. Available in PDF, EPUB and Kindle. Book excerpt: Exhaled air contains numerous substances, often in extremely low concentrations. The development of sensitive detection techniques has made it possible to examine the composition of exhaled air in relation to a variety of airway diseases and other disorders. In this book, an overview of current cutting-edge breath analysis techniques and their clinical applications is provided for the clinician. The various contributions give a fascinating perspective of a future where new, highly sensitive methodologies will enable clinicians to diagnose and monitor a wide variety of diseases merely by taking.
Download or read book Asthma written by Graeme P. Currie and published by Oxford University Press. This book was released on 2012-08-30 with total page 162 pages. Available in PDF, EPUB and Kindle. Book excerpt: Asthma is a common chronic condition affecting the airways. It is becoming increasingly recognised by health care workers. Epidemiological studies suggest that, along with other atopic diseases, its prevalence is rising. This book will provide a practical, evidence-based guide to the main aspects of asthma.
Download or read book Paediatric Asthma written by Kai-Håkon Carlsen and published by European Respiratory Society. This book was released on 2012-06-01 with total page 246 pages. Available in PDF, EPUB and Kindle. Book excerpt: Asthma is a disease of many faces and is frequently seen in children. This Monograph covers all aspects of paediatric asthma, across all ages, from birth through to the start of adulthood. It considers diagnostic problems in relation to the many phenotypes of asthma, covers the treatment of both mild-to-moderate and severe asthma, and discusses asthma exacerbations as well as exercise-induced asthma. The issue also provides an update on the pathophysiology of asthma, the role of bacterial and viral infections, and the impact of environmental factors, allergy, genetics and epigenetics. Finally,
Download or read book Pediatric Allergy Asthma and Immunology written by Arnaldo Cantani and published by Springer Science & Business Media. This book was released on 2008-01-23 with total page 1634 pages. Available in PDF, EPUB and Kindle. Book excerpt: Easy to understand and easy to use, this essential book reflects the rapid progress in one of the most intriguing fields of medicine. It offers state-of-the-art information on basic immunology, fetal-neonatal immunology, and many more fascinating areas.
Download or read book Asthma written by Richard F. Lockey and published by Oxford University Press, USA. This book was released on 2014 with total page 513 pages. Available in PDF, EPUB and Kindle. Book excerpt: Diagnosing asthma requires knowledge of the multiple conditions that emulate it, and treatment requires addressing factors that modify the disease. This comprehensive, single reference will help practitioners identify and care for co-morbid conditions and improve asthma treatment.
Download or read book Epigenetic Approaches to Allergy Research written by Marién Pascual and published by Springer Science & Business Media. This book was released on 2013-01-20 with total page 71 pages. Available in PDF, EPUB and Kindle. Book excerpt: In recent years, epigenetic approaches to existing scientific problems have offered many new and exciting perspectives. This book focuses on epigenetic approaches to study asthma and allergy research. The authors briefly review cellular factors, immune signaling, and inflammatory pathways in allergy and asthma, as well as genetic influences in the pathogenesis of atopic disorders. Diseases that have been clearly linked to an epigenetic dysregulation will be discussed, as well as the role of epigenetics in the origin of complex diseases. The authors will examine the impact of environment factors in the predisposition to atopic disorders, and they will also describe the major unanswered questions and future perspectives of an exciting new field that studies allergic diseases from the epigenetic point of view.
Download or read book Allergy written by Royal College of Physicians of London and published by Royal College of Physicians. This book was released on 2003 with total page 116 pages. Available in PDF, EPUB and Kindle. Book excerpt:
