Download or read book Genetic and Biochemical Determinants of Legionella Pneumophila Pathogenesis in Dictyostelium Discoideum written by Chenyu Zhang and published by . This book was released on 2006 with total page 340 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Management of Legionella in Water Systems written by National Academies of Sciences, Engineering, and Medicine and published by National Academies Press. This book was released on 2020-02-20 with total page 291 pages. Available in PDF, EPUB and Kindle. Book excerpt: Legionnaires' disease, a pneumonia caused by the Legionella bacterium, is the leading cause of reported waterborne disease outbreaks in the United States. Legionella occur naturally in water from many different environmental sources, but grow rapidly in the warm, stagnant conditions that can be found in engineered water systems such as cooling towers, building plumbing, and hot tubs. Humans are primarily exposed to Legionella through inhalation of contaminated aerosols into the respiratory system. Legionnaires' disease can be fatal, with between 3 and 33 percent of Legionella infections leading to death, and studies show the incidence of Legionnaires' disease in the United States increased five-fold from 2000 to 2017. Management of Legionella in Water Systems reviews the state of science on Legionella contamination of water systems, specifically the ecology and diagnosis. This report explores the process of transmission via water systems, quantification, prevention and control, and policy and training issues that affect the incidence of Legionnaires' disease. It also analyzes existing knowledge gaps and recommends research priorities moving forward.
Download or read book Legionella Pneumophila Pathogenesis and Immunity written by Paul Hoffman and published by Springer Science & Business Media. This book was released on 2007-10-24 with total page 217 pages. Available in PDF, EPUB and Kindle. Book excerpt: The volume brings together all of the latest research on this pathogen, the interest in which is rapidly growing. Legionella pneumophila is an emerging human pathogen that resides in natural environments as a parasite of freshwater. There have been major new developments in this field, including the publication of three whole genome sequences and the discovery of a developmental cycle and novel cyst-like highly infectious form.
Download or read book Molecular Mechanisms in Legionella Pathogenesis written by Hubert Hilbi and published by Springer Science & Business Media. This book was released on 2014-07-08 with total page 297 pages. Available in PDF, EPUB and Kindle. Book excerpt: Legionnaires’ disease, a potentially fatal type of pneumonia primarily affecting elderly and immuno-compromised persons, is caused by the ubiquitous environmental bacterium Legionella pneumophila. This book offers authoritative reviews of different facets of its virulence, focusing on comparative phagocyte infection, virulence gene regulation, biochemical functions of effector proteins and cellular pathogen-host interactions, as well as host responses and immunity to L. pneumophila. Taken together, the contributions in this compilation provide a state-of-the-art overview of current insights into the molecular pathogenesis of the opportunistic and potentially fatal pathogen L. pneumophila.
Download or read book Bacterial Biofilms written by Sadik Dincer and published by BoD – Books on Demand. This book was released on 2020-10-07 with total page 362 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book examines biofilms in nature. Organized into four parts, this book addresses biofilms in wastewater treatment, inhibition of biofilm formation, biofilms and infection, and ecology of biofilms. It is designed for clinicians, researchers, and industry professionals in the fields of microbiology, biotechnology, ecology, and medicine as well as graduate and postgraduate students.
Download or read book Microbial Growth in Drinking Water Supplies written by Dick van der Kooij and published by IWA Publishing. This book was released on 2013-09-14 with total page 484 pages. Available in PDF, EPUB and Kindle. Book excerpt: Maintaining the microbial quality in distribution systems and connected installations remains a challenge for the water supply companies all over the world, despite many years of research. This book identifies the main concerns and knowledge gaps related to regrowth and stimulates cooperation in future research. Microbial Growth in Drinking Water Supplies provides an overview of the regrowth issue in different countries and the water quality problems related to regrowth. The book assesses the causes of regrowth in drinking water and the prevention of regrowth by water treatment and distribution. Editors: Dirk van der Kooij and Paul W.J.J. van der Wielen, KWR Watercycle Research Institute, The Netherlands
Download or read book Soil Protists written by Stefan Geisen and published by Sudwestdeutscher Verlag Fur Hochschulschriften AG. This book was released on 2015-10-13 with total page 328 pages. Available in PDF, EPUB and Kindle. Book excerpt: Protists are by far the most diverse and abundant eukaryotes in soils. Nevertheless, very little is known about individual representatives, the diversity and community composition and ecological functioning of these important organisms. For instance, soil protists are commonly lumped into a single functional unit, i.e. bacterivores. This work tackles missing knowledge gaps on soil protists and common misconceptions using multi-methodological approaches including cultivation, microcosm experiments and environmental sequencing. In a first part, several new species and genera of amoeboid protists are described showing their immense unknown diversity. In the second part, the enormous complexity of soil protists communities is highlighted using cultivation- and sequence-based approaches. In the third part, the present of diverse mycophagous and nematophagous protists are shown in functional studies on cultivated taxa and their environmental importance supported by sequence-based approaches. This work is just a start for a promising future of soil Protistology that is likely to find other important roles of these diverse organisms.
Download or read book Myeloid Cells in Health and Disease written by Siamon Gordon and published by John Wiley & Sons. This book was released on 2020-07-10 with total page 892 pages. Available in PDF, EPUB and Kindle. Book excerpt: The structure, functions, and interactions of myeloid cells have long been the focus of research and therapeutics development. Yet, much more remains to be discovered about the complex web of relationships that makes up the immune systems of animals. Scientists today are applying genome-wide analyses, single-cell methods, gene editing, and modern imaging techniques to reveal new subclasses of differentiated myeloid cells, new receptors and cytokines, and important interactions among immune cells. In Myeloid Cells in Health and Disease: A Synthesis, Editor Siamon Gordon has assembled an international team of esteemed scientists to provide their perspectives of myeloid cells during innate and adaptive immunity. The book begins by presenting the foundational research of Paul Ehrlich, Elie Metchnikoff, and Donald Metcalf. The following chapters discuss evolution and the life cycles of myeloid cells; specific types of differentiated myeloid cells, including macrophage differentiation; and antigen processing and presentation. The rest of the book is organized by broad topics in immunology, including the recruitment of myeloid and other immune cells following microbial infection the role of myeloid cells in the inflammation process and the repair of damaged tissue the vast arsenal of myeloid cell secretory molecules, including metalloproteinases, tumor necrosis factor, histamine, and perforin receptors and downstream signaling pathways that are activated following ligand-receptor binding roles of myeloid cells during microbial and parasite infections contributions of myeloid cells in atherosclerosis myeloid-derived suppressor cells in tumor development and cancer Myeloid Cells in Health and Disease: A Synthesis will benefit graduate students and researchers in immunology, hematology, microbial pathogenesis, infectious disease, pathology, and pharmacology. Established scientists and physicians in these and related fields will enjoy the book's rich history of myeloid cell research and suggestions for future research directions and potential therapies.
Download or read book Environmental Aspects of Zoonotic Diseases written by Robert Armon and published by IWA Publishing. This book was released on 2012-01-31 with total page 517 pages. Available in PDF, EPUB and Kindle. Book excerpt: Environmental Aspects of Zoonotic Diseases provides a definitive description, commentary and research needs of environmental aspects related to zoonotic diseases. There are many interrelated connections between the environment and zoonotic diseases such as: water, soil, air and agriculture. The book presents investigations of these connections, with specific reference to environmental processes such as: deforestation, floods, draughts, irrigation practices, soil transfer and their impact on bacterial, viral, fungal, and parasitological spread. Environmental aspects such as climate (tropical, sub-tropical, temperate, arid and semi-arid), developed and undeveloped countries, animal (domestic and wild) traffic animal border crossing, commercial animal trade, transportation, as well geography and weather on zoonosis, are also discussed and relevant scientific data is condensed and organized in order to give a better picture of interrelationship between the environment and current spread of zoonotic diseases. Altogether, the book presents a remarkable and a vast amount of potential future research directions based on the link: environment-vectors-pathogens-humans. The most up-to-date source of information on this increasingly important cross-disciplinary subject, Environmental Aspects of Zoonotic Diseases will be invaluable for environmentalists, veterinarians, medical staff, environmental engineers, government agencies and consultants working in this field. Authors: Prof. Robert Armon, Technion (Israel Institute of Technology), Haifa, Israel, Dr. Uta Cheruti, Technion (Israel Institute of Technology), Haifa, Israel
Download or read book Research Awards Index written by and published by . This book was released on 1982 with total page 1170 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Pathogenic Bacteria written by Sahra Kırmusaoğlu and published by BoD – Books on Demand. This book was released on 2020-12-09 with total page 248 pages. Available in PDF, EPUB and Kindle. Book excerpt: Pathogenic bacteria are the main problem in hospital- and community-acquired infections. As bacteria continue to develop more resistance to antibiotics, it is imperative to develop antibacterial treatment strategies. Written by experts from all over the world, this book examines pathogenic bacteria and their link to multidrug resistance. Over thirteen chapters, it presents examples of pathogenesis, virulence factors, and treatment strategies.
Download or read book Bacterial Resistance to Antibiotics written by Boyan B. Bonev and published by John Wiley & Sons. This book was released on 2019-06-10 with total page 288 pages. Available in PDF, EPUB and Kindle. Book excerpt: AN AUTHORITATIVE SURVEY OF CURRENT RESEARCH INTO CLINICALLY USEFUL CONVENTIONAL AND NONCONVENTIONAL ANTIBIOTIC THERAPEUTICS Pharmaceutically-active antibiotics revolutionized the treatment of infectious diseases, leading to decreased mortality and increased life expectancy. However, recent years have seen an alarming rise in the number and frequency of antibiotic-resistant "Superbugs." The Centers for Disease Control and Prevention (CDC) estimates that over two million antibiotic-resistant infections occur in the United States annually, resulting in approximately 23,000 deaths. Despite the danger to public health, a minimal number of new antibiotic drugs are currently in development or in clinical trials by major pharmaceutical companies. To prevent reverting back to the pre-antibiotic era—when diseases caused by parasites or infections were virtually untreatable and frequently resulted in death—new and innovative approaches are needed to combat the increasing resistance of pathogenic bacteria to antibiotics. Bacterial Resistance to Antibiotics – From Molecules to Man examines the current state and future direction of research into developing clinically-useful next-generation novel antibiotics. An internationally-recognized team of experts cover topics including glycopeptide antibiotic resistance, anti-tuberculosis agents, anti-virulence therapies, tetracyclines, the molecular and structural determinants of resistance, and more. Presents a multidisciplinary approach for the optimization of novel antibiotics for maximum potency, minimal toxicity, and appropriated degradability Highlights critical aspects that may relieve the problematic medical situation of antibiotic resistance Includes an overview of the genetic and molecular mechanisms of antibiotic resistance Addresses contemporary issues of global public health and longevity Includes full references, author remarks, and color illustrations, graphs, and charts Bacterial Resistance to Antibiotics – From Molecules to Man is a valuable source of up-to-date information for medical practitioners, researchers, academics, and professionals in public health, pharmaceuticals, microbiology, and related fields.
Download or read book The Rasputin Effect When Commensals and Symbionts Become Parasitic written by Christon J. Hurst and published by Springer. This book was released on 2016-07-05 with total page 364 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume focuses on those instances when benign and even beneficial relationships between microbes and their hosts opportunistically change and become detrimental toward the host. It examines the triggering events which can factor into these changes, such as reduction in the host’s capacity for mounting an effective defensive response due to nutritional deprivation, coinfections and seemingly subtle environmental influences like the amounts of sunlight, temperature, and either water or air quality. The effects of environmental changes can be compounded when they necessitate a physical relocation of species, in turn changing the probability of encounter between microbe and host. The change also can result when pathogens, including virus species, either have modified the opportunist or attacked the host’s protective natural microflora. The authors discuss these opportunistic interactions and assess their outcomes in both aquatic as well as terrestrial ecosystems, highlighting the impact on plant, invertebrate and vertebrate hosts.
Download or read book Dictyostelids written by Maria Romeralo and published by Springer. This book was released on 2013-07-30 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Since their discovery in 1869, the dictyostelids have attracted the attention of scientists in a wide variety of fields. This interest has stemmed from their peculiar lifestyle and developmental properties, which were shaped by the evolutionary forces that generated multicellularity during eukaryotic evolution. More recently, the dictyostelids have gained attention due to the striking similarities found at the genomic, cellular and biochemical levels with human cells, which has propelled the species Dictyostelium discoideum to become a model system for biology and medicine in many laboratories. This book covers the latest advances in our knowledge of these extraordinary organisms with topics spanning from their evolutionary history, ecology and diversity to the recent discoveries regarding their cellular and molecular biology.
Download or read book Bacterial Virulence Factors and Rho GTPases written by Patrice Boquet and published by Springer Science & Business Media. This book was released on 2005-04-01 with total page 216 pages. Available in PDF, EPUB and Kindle. Book excerpt: Pathogenic bacteria for human and animals have developed sophisticated weapons, termed virulence factors, to ensure their replication and persistence into their hosts. The authors in this volume show a synthesis on how the various host cellular Rho GTPases activities are manipulated by bacteria to fulfil their virulence.
Download or read book Legionella Pneumophila Pathogenesis and Immunity written by Paul Hoffman and published by Springer. This book was released on 2010-11-25 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: The volume brings together all of the latest research on this pathogen, the interest in which is rapidly growing. Legionella pneumophila is an emerging human pathogen that resides in natural environments as a parasite of freshwater. There have been major new developments in this field, including the publication of three whole genome sequences and the discovery of a developmental cycle and novel cyst-like highly infectious form.
Download or read book Type IV Secretion in Gram Negative and Gram Positive Bacteria written by Steffen Backert and published by Springer. This book was released on 2018-03-13 with total page 364 pages. Available in PDF, EPUB and Kindle. Book excerpt: Type IV secretion systems (T4SSs) are highly versatile membrane-associated transporter machines used by Gram-negative and Gram-positive bacteria to deliver substrate molecules to a large variety of target cells. This volume summarizes our current knowledge of the large variety and structural diversity of T4SSs in pathogenic Escherichia, Agrobacterium, Legionella, Coxiella, Bartonella, Helicobacter, Enterococcus and other species. Divided into 13 chapters contributed by leading experts, it presents findings that significantly enhance our understanding of how various pathogens manipulate host cell functions to trigger bacterial uptake, promote intracellular growth, suppress defense mechanisms and of how bacteria spread antibiotic resistances, thus facilitating bacterial colonization and disease development. The book is an invaluable source of information for researchers and clinicians.
