Download or read book Gene regulation of fungal secondary metabolism written by Wenbing Yin and published by Frontiers Media SA. This book was released on 2023-09-08 with total page 147 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Biosynthesis and Molecular Genetics of Fungal Secondary Metabolites written by Juan-Francisco Martín and published by Springer. This book was released on 2014-09-09 with total page 357 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume describes the more relevant secondary metabolites of different fungi with current information on their biosynthesis and molecular genetics. Bolstered with color illustrations and photographs, the book describes the possible application of molecular genetics to directed strain improvement in great detail. The needs for future developments in this field are also discussed at length Written by authorities in the field, Biosynthesis and Molecular Genetics of Fungal Secondary Metabolites provides a cutting-edge perspective on fungal secondary metabolism and underlying genetics and is a valuable resource for scientists, researchers, and educators in the field of fungal biology.

Download or read book Fungal Secondary Metabolism written by Nancy P. Keller and published by Humana Press. This book was released on 2012-10-14 with total page 288 pages. Available in PDF, EPUB and Kindle. Book excerpt: Filamentous fungi have long been known for their ability to produce an enormous range of unusual chemical compounds known as secondary metabolites, many of which have potentially useful antibiotic or pharmacological properties. Recent focus on fungal genomics coupled with advances in detection and molecular manipulation techniques has galvanized a revitalization of this field. Fungal Secondary Metabolism: Methods and Protocols is aimed at providing the key methodologies currently in use and necessary for accessing and exploiting the natural product information provided by the genomes of this large and varied kingdom. Written by active researchers in the field, the chapters deal with all the steps necessary, from optimization of fungal culture conditions for metabolite production, through rapid genome sequencing and bioinformatics, and genetic manipulations for functional analysis, to detection and testing of metabolites. In addition, chapters on basic science address approaches to the genetic regulation, protein biochemistry, and cellular localization of the biosynthetic pathways. Written in the highly successful Methods in Molecular BiologyTM series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Practical and hands-on, Fungal Secondary Metabolism: Methods and Protocols encourages new investigators to enter the field and expands upon the expertise and range of skills of those already researching fungal natural products.

Download or read book Fungal Jewels Secondary Metabolites written by Nancy Keller and published by Frontiers Media SA. This book was released on 2017-04-10 with total page 205 pages. Available in PDF, EPUB and Kindle. Book excerpt: Fungal natural products are friends and foes of humans such as deleterious mycotoxins, cytotoxic, carcinogenic compounds or beneficial compounds such as antibiotics, fungicides, insecticides, antiviral and antitumor metabolites. Understanding fungal diversity and estimation of fungal species on our planet poses a great challenge to researchers. This complexity is further multiplied by secondary metabolite diversity of fungi, which requires interdisciplinary studies. It is extremely important to understand the fungal secondary metabolism to stop human, animal and plant diseases caused by fungi and harvest their valuable metabolites. Furthermore, many secondary metabolite gene clusters are silenced under laboratory conditions. It is vital to develop effective methods to activate those clusters in order to discover novel potent metabolites. This e-book is a compilation of original review articles contributed by leading fungal secondary metabolite researchers with a wide range of expertise. Important aspects of fungal secondary metabolism, including regulation, genome mining, evolution, synthetic biology and novel methods have been discussed. This book will be a great source to those people, who are interested in understanding overall structure, diversity and regulation of production of these tiny but precious chemicals.

Download or read book Biosynthesis and Molecular Genetics of Fungal Secondary Metabolites Volume 2 written by Susanne Zeilinger and published by Springer. This book was released on 2015-06-15 with total page 263 pages. Available in PDF, EPUB and Kindle. Book excerpt: ​Fungi produce many chemically diverse secondary metabolites whose biological roles largely remain elusive. Within the increasing number of sequenced fungal genomes several important genes involved in secondary metabolite formation have been identified. Most of these genes are clustered and their coordinated transcription is controlled in a complex way by both narrow pathway-specific regulators as well as broad global transcription factors responsive to environmental cues. In recent years it was discovered many of the newly identified gene clusters are silent under laboratory conditions suggesting that the biosynthetic potential of fungi is far from being exploited. Besides identifying novel bioactive metabolites from still unexplored sources, the activation of these gene clusters by several approaches may result in the discovery of new substances with antibiotic and pharmaceutical benefits. This book covers recent advances in the field of fungal secondary metabolisms ranging from methodologies to biological aspects and will include the latest knowledge on fungal molecular biology, genomics, and metabolomics. With the related volume by Professor Juan-Francisco Martin, where the most relevant and well-studied fungal secondary metabolites are compiled, this book provides a comprehensive overview of the state-of-the-art of research on fungal secondary metabolites.

Download or read book Fungal Secondary Metabolism written by Nancy P. Keller and published by Humana Press. This book was released on 2016-05-01 with total page 302 pages. Available in PDF, EPUB and Kindle. Book excerpt: This Methods in Molecular Biology volume provides key methodologies for accessing and exploiting natural product information provided by the genomes of filamentous fungi. Includes materials and reagents lists, step-by-step protocols and troubleshooting tips."

Download or read book Gene Expression Systems in Fungi Advancements and Applications written by Monika Schmoll and published by Springer. This book was released on 2016-04-04 with total page 505 pages. Available in PDF, EPUB and Kindle. Book excerpt: Biotechnology has emerged as one of the key environmentally safe technologies for the future which enables use of biomass to develop novel smart materials and to replace oil derived products. Fungi are the most efficient producers of the enzymes needed for this purpose and in addition they produce a plethora of secondary metabolites, among which novel antibiotics can be found. Industrial application and exploitation of the metabolic capacities of fungi requires highly productive and robust gene expression systems, which can be achieved by selection of appropriate species and strain improvement. In this book we aim to summarize homologous and heterologous gene expression systems of fungi for production of enzymes and secondary metabolites. A broad overview on requirements, challenges and successful applications shall serve as a basis for further development of fungi as biotechnological workhorses in research and industry.

Download or read book Secondary Metabolism and Differentiation in Fungi written by Bennett and published by CRC Press. This book was released on 2020-11-25 with total page 495 pages. Available in PDF, EPUB and Kindle. Book excerpt: The first source to unite secondary fungal metabolism and morphogenesis in one volume, Secondary Metabolism and Differentiation in Fungi treats biological systems as parts of a whole rather than as a series of individual elements, highlighting research in genetics, molecular biology, and ecology. Featuring the expertise of 19 international authorities, each chapter is a rich source of experimentation ideas. The book facilitates the application of novel techniques to existing problems in molecular mycology and explores potentials for major new research. This indispensable guide to a key scientific field benefits biologists, chemists, and other scientists.

Download or read book Fungal Metabolites written by Jean-Michel Mérillon and published by . This book was released on with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Microbial Technology for the Welfare of Society written by Pankaj Kumar Arora and published by Springer Nature. This book was released on 2019-09-12 with total page 341 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book describes various aspects of modern microbiology including microbial enzymes, secondary metabolites, next-generation sequencing, microbial-based biopesticides, microbial-based cancer therapies, biodiesel, and microbial products from fermentation, biodegradation, bioremediation and wastewater treatment. Further, it explains how and why microbes play an important role in preserving the welfare of living beings and the environment. Many bacteria play a significant part in cleaning our environment by detoxifying various xenobiotic compounds, while several microbes produce secondary metabolites that are useful to human beings. The book is divided into 15 chapters that cover various aspects of microorganism-based biotechnology, including recent methodologies such as advanced molecular techniques, as well developments in classical microbiological techniques. The authors also explain how the latest and classical techniques are being used in modern-day microbial biotechnology. All chapters were written by experts from prominent universities, research laboratories, and institutes around the globe. Above all, they focus on recent advances in microbial technology that promote the welfare of living beings and the environment.

Download or read book Fungal Primary and Secondary Metabolism and its Importance for Virulence and Biomedical Applications written by Fernando Rodrigues and published by Frontiers Media SA. This book was released on 2021-06-23 with total page 164 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Alterations in Gene Expression and Secondary Metabolite Production During Development of Aspergillus Nidulans written by Marc Dumkow and published by . This book was released on 2013 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Many studies describing development and secondary metabolism of the filamentous fungus Aspergillus nidulans contributed to a better understanding of fungal secondary metabolism regulation at the molecular level. However, a comprehensive picture of the regulation remained to be shown. Therefore, in this work we undertake a global transcriptomic and metabolomic overview, which describes the light-dependent developmental responses of this soil-borne fungus. Light favours the development of asexual spores and inhibits the formation of sexual fruiting bodies (cleistothecia), which are preferenti ...

Download or read book Fungal Secondary Metabolites written by Kamel A. Abd-Elsalam and published by Elsevier. This book was released on 2023-09-19 with total page 586 pages. Available in PDF, EPUB and Kindle. Book excerpt: Fungal Secondary Metabolites: Synthesis and Applications in Agroecosystem presents the properties and biotechnological applications of microbial metabolites and their industrial, pharmaceutical, antimicrobial, and anticancer applications. Chapters cover topics such as the role of fungal metabolites in the management of abiotic stress, microbial alkaloids and their pharmaceutical and agricultural applications, and fungal metabolites as novel plant pathogen antagonists. Plant and agri-food environmental scientists, researchers, graduate, and post-graduate students in related fields will find value in this reference which is published as part of the series Nanobiotechnology for Plant Protection. - Addresses the link between fungal secondary metabolites and health - Covers cryptic genes and their link to the production of bioactive compounds - Explores possibilities for producing bio-based business solutions

Download or read book The Fungal Kingdom written by Joseph Heitman and published by John Wiley & Sons. This book was released on 2020-07-10 with total page 1136 pages. Available in PDF, EPUB and Kindle. Book excerpt: Fungi research and knowledge grew rapidly following recent advances in genetics and genomics. This book synthesizes new knowledge with existing information to stimulate new scientific questions and propel fungal scientists on to the next stages of research. This book is a comprehensive guide on fungi, environmental sensing, genetics, genomics, interactions with microbes, plants, insects, and humans, technological applications, and natural product development.

Download or read book Secondary Metabolites in Soil Ecology written by Petr Karlovsky and published by Springer Science & Business Media. This book was released on 2008-01-03 with total page 296 pages. Available in PDF, EPUB and Kindle. Book excerpt: Microbiologists and soil scientists will find this study compelling reading. It focuses on the role of bacterial, fungal and plant secondary metabolites in soil ecosystems. Our understanding of the biological function of secondary metabolites is surprisingly limited, considering our knowledge of their structural diversity and pharmaceutical activity. This book reviews functional aspects of secondary metabolite production, with a focus on interactions among soil organisms.

Download or read book Endophytes and Secondary Metabolites written by Sumita Jha and published by Springer. This book was released on 2019-07-24 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: This reference work presents an authoritative review of endophytes and their applications to human welfare. Endophytes have become a class of interesting and curious microorganisms due to their intimate intra- and intercellular association with plants for competence, survival and reproduction. They can be bacteria or fungi, and they are usually non-pathogenic to their host. Endophytes have important applications in agriculture and industry, namely, they can help with plant growth, act as biocontrol agents and biosurfactant and secondary metabolite producers, and they are also rich sources of bioactive natural products. Novel and beneficial effects of endophytes are constantly emerging, and this book, divided into four sections, provides readers with the latest developments in this fast expanding field. In the first section, readers will discover the biology of the major groups of endophytes, followed by a summary of conventional and molecular tools for endophytes’ identification in Section II. The production of high-value metabolites by endophytes will be explored in the third section of this book, and in the final section, readers will find several case studies, examples and prospects for endophytes’ application in agriculture and industry. Written by leading international authors, this reference work will appeal to a wide readership, from students and researchers in the field of botany, biotechnology and agriculture to professionals interested in the production and applications of endophytic metabolites.

Download or read book Fungal Jewels Secondary Metabolites written by and published by . This book was released on 2017 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Fungal natural products are friends and foes of humans such as deleterious mycotoxins, cytotoxic, carcinogenic compounds or beneficial compounds such as antibiotics, fungicides, insecticides, antiviral and antitumor metabolites. Understanding fungal diversity and estimation of fungal species on our planet poses a great challenge to researchers. This complexity is further multiplied by secondary metabolite diversity of fungi, which requires interdisciplinary studies. It is extremely important to understand the fungal secondary metabolism to stop human, animal and plant diseases caused by fungi and harvest their valuable metabolites. Furthermore, many secondary metabolite gene clusters are silenced under laboratory conditions. It is vital to develop effective methods to activate those clusters in order to discover novel potent metabolites. This e-book is a compilation of original review articles contributed by leading fungal secondary metabolite researchers with a wide range of expertise. Important aspects of fungal secondary metabolism, including regulation, genome mining, evolution, synthetic biology and novel methods have been discussed. This book will be a great source to those people, who are interested in understanding overall structure, diversity and regulation of production of these tiny but precious chemicals.