Download or read book Gapp s Generation written by Wade Powers and published by AuthorHouse. This book was released on 2019-10-14 with total page 267 pages. Available in PDF, EPUB and Kindle. Book excerpt: John Gapp lives in Seattle, Washington as a retired and decorated police officer. A series of personal tragedies has left the man as a frightened soul and an agoraphobic. One highlight of Gapp’s life is his radio show, which is broadcast from a studio that is adjacent to his apartment. Crime on Ice, is a hit and has just been syndicated. While working through his demons of the present, an old one comes calling. A serial killer of children that Gapp had almost apprehended in Vietnam in 1968 is up to his old game again. In 2008, he attempts to draw John Gapp out of hiding for one last showdown. At age sixty-two, the former detective must make the choice if he is to face the world and attempt to bring down this dark angel of death. Can Gapp stand on the sidelines while more young lives are destroyed?
Download or read book Gapp s Generation written by Wade Powers and published by AuthorHouse. This book was released on 2019-10-14 with total page 267 pages. Available in PDF, EPUB and Kindle. Book excerpt: John Gapp lives in Seattle, Washington as a retired and decorated police officer. A series of personal tragedies has left the man as a frightened soul and an agoraphobic. One highlight of Gapp’s life is his radio show, which is broadcast from a studio that is adjacent to his apartment. Crime on Ice, is a hit and has just been syndicated. While working through his demons of the present, an old one comes calling. A serial killer of children that Gapp had almost apprehended in Vietnam in 1968 is up to his old game again. In 2008, he attempts to draw John Gapp out of hiding for one last showdown. At age sixty-two, the former detective must make the choice if he is to face the world and attempt to bring down this dark angel of death. Can Gapp stand on the sidelines while more young lives are destroyed?
Download or read book Gapp s Generation written by Wade Powers and published by . This book was released on 2019-10-14 with total page 270 pages. Available in PDF, EPUB and Kindle. Book excerpt: John Gapp lives in Seattle, Washington as a retired and decorated police officer. A series of personal tragedies has left the man as a frightened soul and an agoraphobic. One highlight of Gapp's life is his radio show, which is broadcast from a studio that is adjacent to his apartment. Crime on Ice, is a hit and has just been syndicated. While working through his demons of the present, an old one comes calling. A serial killer of children that Gapp had almost apprehended in Vietnam in 1968 is up to his old game again. In 2008, he attempts to draw John Gapp out of hiding for one last showdown. At age sixty-two, the former detective must make the choice if he is to face the world and attempt to bring down this dark angel of death. Can Gapp stand on the sidelines while more young lives are destroyed?
Download or read book Mechanics and Energetics of the Myocardium written by Christian J.F. Holubarsch and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 219 pages. Available in PDF, EPUB and Kindle. Book excerpt: During several decades of this century, the classical physiological studies on the cardiovascular system have greatly improved our knowledge on the function of this system under normal and pathological conditions. This knowledge was the basis of the breakthrough for diagnostic techniques like the Swan-Ganz catheter, coronary arteriography, left and right heart biopsies, and invasive measurements of contractility, as well as therapeutic tools including aortocoronary bypass surgery, percutanous transluminal coronary angioplasty, and a broad field of pharmacological interventions for the whole spectrum of cardiovascular diseases, especially chronic heart failure. It was during the last decade that the scientific world focused on the evolution of molecular biology of the cardiovascular system so that cardiovascular physiology seemed to become less important. Regarding the myocardium, molecular alterations of important functional proteins (phenotype changes), as well as signal transduction pathways of contractility and cardiac growth have been elucidated. The functional importance of a number of genes has undoubtedly been proven with the help of transgenic animals. Mechanics and Energetics of the Myocardium provides an overview for those researchers and practioners interested in the broad field of molecular biology and physiology of the cardiovascular system.
Download or read book Cellular Automata and Modeling of Complex Physical Systems written by Paul Manneville and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 326 pages. Available in PDF, EPUB and Kindle. Book excerpt: Cellular automata are fully discrete dynamical systems with dynamical variables defined at the nodes of a lattice and taking values in a finite set. Application of a local transition rule at each lattice site generates the dynamics. The interpretation of systems with a large number of degrees of freedom in terms of lattice gases has received considerable attention recently due to the many applications of this approach, e.g. for simulating fluid flows under nearly realistic conditions, for modeling complex microscopic natural phenomena such as diffusion-reaction or catalysis, and for analysis of pattern-forming systems. The discussion in this book covers aspects of cellular automata theory related to general problems of information theory and statistical physics, lattice gas theory, direct applications, problems arising in the modeling of microscopic physical processes, complex macroscopic behavior (mostly in connection with turbulence), and the design of special-purpose computers.
Download or read book Perspectives in Computational Complexity written by Manindra Agrawal and published by Springer. This book was released on 2014-07-16 with total page 206 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book brings together contributions by leading researchers in computational complexity theory written in honor of Somenath Biswas on the occasion of his sixtieth birthday. They discuss current trends and exciting developments in this flourishing area of research and offer fresh perspectives on various aspects of complexity theory. The topics covered include arithmetic circuit complexity, lower bounds and polynomial identity testing, the isomorphism conjecture, space-bounded computation, graph isomorphism, resolution and proof complexity, entropy and randomness. Several chapters have a tutorial flavor. The aim is to make recent research in these topics accessible to graduate students and senior undergraduates in computer science and mathematics. It can also be useful as a resource for teaching advanced level courses in computational complexity.
Download or read book The Complexity Theory Companion written by Lane A. Hemaspaandra and published by Springer Science & Business Media. This book was released on 2013-03-14 with total page 375 pages. Available in PDF, EPUB and Kindle. Book excerpt: Here is an accessible, algorithmically oriented guide to some of the most interesting techniques of complexity theory. The book shows that simple algorithms are at the heart of complexity theory. The book is organized by technique rather than by topic. Each chapter focuses on one technique: what it is, and what results and applications it yields.
Download or read book Proceedings written by and published by . This book was released on 1988 with total page 424 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Stress Resilience written by Alon Chen and published by Academic Press. This book was released on 2019-10-31 with total page 390 pages. Available in PDF, EPUB and Kindle. Book excerpt: Stress Resilience: Molecular and Behavioral Aspects presents the first reference available on the full-breadth of cutting-edge research being carried out in this field. It includes a wide range of basic molecular knowledge on the potential associations between resilience phenomenon and biochemical balance, but also focuses on the molecular and cellular mechanisms underlying stress resilience. World-renowned experts provide chapters that cover everything from the neural circuits of resilience, the effects of early-life adversity, and the transgenerational inheritance of resilience. This unique and timely book will be a go-to resource for neuroscientists and biological psychiatrists who want to improve their understanding of the consequences of stress and on how some people are able to avoid it. Approaches resilience as a process rather than as a static trait Provides basic molecular knowledge on the potential associations between resilience phenomenon and biochemical balance Presents thorough coverage of both the genetic and environmental factors that contribute to resilience
Download or read book Effects of Early Life Stress on Neurodevelopment and Health Bridging the Gap Between Human Clinical Studies and Animal Models written by Arie Kaffman and published by Frontiers Media SA. This book was released on 2021-12-01 with total page 247 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Gabbard s Textbook of Psychotherapeutic Treatments Second Edition written by Holly Crisp, M.D. and published by American Psychiatric Pub. This book was released on 2022-09-21 with total page 832 pages. Available in PDF, EPUB and Kindle. Book excerpt: "The second edition of Gabbard's Textbook of Psychotherapeutic Treatments provides up-to-date information on psychotherapies, including psychodynamic therapies, mentalization-based treatment, transference-focused therapy, cognitive-behavioral therapy, supportive psychotherapy, and interpersonal psychotherapy. The textbook also reflects social changes that have had profound impacts on how therapists practice, including the advancement of LGBTQ rights, calls for racial and social justice, and the COVID-19 pandemic"--
Download or read book Non Equilibrium Reacting Gas Flows written by Ekaterina Nagnibeda and published by Springer Science & Business Media. This book was released on 2009-07-09 with total page 255 pages. Available in PDF, EPUB and Kindle. Book excerpt: In the present monograph, we develop the kinetic theory of transport phenomena and relaxation processes in the flows of reacting gas mixtures and discuss its applications to strongly non-equilibrium conditions. The main attention is focused on the influence of non-equilibrium kinetics on gas dynamics and transport properties. Closed systems of fluid dynamic equations are derived from the kinetic equations in different approaches. We consider the most accurate approach taking into account the state-to-state kinetics in a flow, as well as simplified multi-temperature and one-temperature models based on quasi-stationary distributions. Within these approaches, we propose the algorithms for the calculation of the transport coefficients and rate coefficients of chemical reactions and energy exchanges in non-equilibrium flows; the developed techniques are based on the fundamental kinetic theory principles. The theory is applied to the modeling of non-equilibrium flows behind strong shock waves, in the boundary layer, and in nozzles. The comparison of the results obtained within the frame of different approaches is presented, the advantages of the new state-to-state kinetic model are discussed, and the limits of validity for simplified models are established. The book can be interesting for scientists and graduate students working on physical gas dynamics, aerothermodynamics, heat and mass transfer, non-equilibrium physical-chemical kinetics, and kinetic theory of gases.
Download or read book Hereditary Gastric and Breast Cancer Syndrome written by Giovanni Corso and published by Springer Nature. This book was released on 2023-03-17 with total page 412 pages. Available in PDF, EPUB and Kindle. Book excerpt: In this book the editors and authors provide a comprehensive overview on basic research and clinical aspects of hereditary breast and gastric tumors. In particular, this updated editorial work aims to suggest guidelines for the clinical management of patients with hereditary diffuse gastric and lobular breast cancer. Special attention is given to E-cadherin (CDH1 gene) germline mutations, genetic screening approaches, the underlying molecular mechanisms and pathological and microscopic features. In addition, the book aims to define clinical criteria for genetic screening, and highlights current surgical treatment and clinical approaches for asymptomatic mutation carriers. Other inherited predispositions involving gastric and breast carcinoma are discussed as well. Divided into eight sections, the book starts by providing an epidemiological overview of gastric and breast cancers, followed by a section dealing with new descriptions of genetic pathways in hereditary cancer predispositions. The third section focuses on pathological features of the diseases, in an effort to bridge the gap between discovery and cancer therapy development. Subsequent sections of the book are dedicated to endoscopy and breast imaging, as well as risk-reducing surgeries to curb the risk of developing cancer. The sixth section focuses on the generation of ideas for the identification of targets and novel treatment strategies. Finally, in the seventh section the authors share the story of two patients and their experiences with the diagnosis and treatment of hereditary cancer. This multidisciplinary book brings together multiple disciplines in science and technology; specifically, medicine, surgery and biology. The majority of authors are members of the International Gastric Cancer Linkage Consortium (IGCLC) and of the European Cancer Prevention Organization (EJCPO), with relevant experience in this context. Offering in-depth insights into hereditary cancers, this book represents essential reading for students, researchers, and specialists who want to extend their knowledge on hereditary gastric and breast cancers.
Download or read book Reliable and Energy Efficient Streaming Multiprocessor Systems written by Anup Kumar Das and published by Springer. This book was released on 2018-01-03 with total page 158 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book discusses analysis, design and optimization techniques for streaming multiprocessor systems, while satisfying a given area, performance, and energy budget. The authors describe design flows for both application-specific and general purpose streaming systems. Coverage also includes the use of machine learning for thermal optimization at run-time, when an application is being executed. The design flow described in this book extends to thermal and energy optimization with multiple applications running sequentially and concurrently.
Download or read book Voltage Gated Calcium Channels written by Gerald Werner Zamponi and published by Springer Science & Business Media. This book was released on 2007-02-26 with total page 392 pages. Available in PDF, EPUB and Kindle. Book excerpt: oltage-gated calcium channels are essential mediators of a range of physiological functions, including the communication between nerve Vcells, the regulation of heart beat, muscle contraction, and secretion of hormones such as insulin. Consequently, these channels are critical phar macological targets in the treatment of a variety of disorders, such as epi lepsy, hypertension, and pain. Voltage-gated calcium channels have there fore been subject to intense study by numerous investigators over the past few decades, and an immense body of work has accumulated. In this book, we provide the first comprehensive overview of our current state of knowl edge concerning this exciting field of research. Leading off with a general review of calcium signaling and techniques to measure calcium channel ac tivity, the book delves into a provocative overview of the history of the cal cium channel field, contributed by one of the key pioneers in the field. Dr. Richard Tsien. This is followed by an in depth review of the biochemical and molecular biological characterization of calcium channel genes by Drs. Catterall and Snutch whose research has resulted in major advances in the calcium channel field. A number of chapters are dedicated towards various aspects of calcium channel structure and function, including channel gat ing, permeation, modulation and interactions with members of the exo- totic machinery—contributed by both established leaders and rising stars in the field.
Download or read book Current Topics in Heart Failure written by Rainer W. G? lch Gerolf Kissling and published by Steinkopff. This book was released on 2013-11-09 with total page 229 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Epigenetics and Neuroendocrinology written by Dietmar Spengler and published by Springer. This book was released on 2016-06-29 with total page 276 pages. Available in PDF, EPUB and Kindle. Book excerpt: The field of neuroendocrinology has extended from the initial interest in the hypothalamic control of pituitary secretion to embrace multiple reciprocal interactions between the central nervous system (CNS) and endocrine systems in the coordination of homeostasis and various physiological responses from adaptation to disease. Most recently, epigenetic mechanisms were recognized for their role in the development of the neuroendocrine axes as well as in the mediation of gene-environment interactions in stress-related psychiatry disorders.
