Download or read book Functional Hydrogels in Drug Delivery written by Umile Gianfranco Spizzirri and published by CRC Press. This book was released on 2017-08-10 with total page 362 pages. Available in PDF, EPUB and Kindle. Book excerpt: The book deals with the synthesis and characterization of hydrogels specifically used as drug delivery systems. Each chapter includes the most recent updates about the different starting materials employed and the improvement of their physicochemical and biological properties to synthetize high performing carriers for specific uses.
Download or read book Functional Hydrogels in Drug Delivery written by Taylor & Francis Group and published by CRC Press. This book was released on 2021-03-31 with total page 362 pages. Available in PDF, EPUB and Kindle. Book excerpt: The book deals with the synthesis and characterization of hydrogels specifically used as drug delivery systems. Each chapter includes the most recent updates about the different starting materials employed and the improvement of their physicochemical and biological properties to synthetize high performing carriers for specific uses.
Download or read book Functional Hydrogels as Biomaterials written by Jun Li and published by Springer. This book was released on 2018-07-17 with total page 163 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book introduces readers to the latest advances in hydrogel biomaterials, mainly focusing on the emerging areas of synthetic and biopolymer hydrogels formed through specially designed chemical or physical crosslinking, and the cyclodextrin-based host-guest supramolecular self-assembly, for cell encapsulation, cell expansion, cell differentiation and tissue repair, stem cell culture, and cellular therapy and drug delivery applications. The book was written by experts at the forefront of these interdisciplinary areas and is intended for all researchers working in the fields of biomaterials and biomedical engineering, as well as medical professions. Jun Li is a Professor at the Department of Biomedical Engineering, National University of Singapore, Singapore. Yoshihito Osada is a Professor at RIKEN Advanced Science Institute, Japan. Justin Cooper-White is a Professor at the Australian Institute for Bioengineering and Nanotechnology, University of Queensland, Australia.
Download or read book Synthesis of Functional Hydrogels written by Weifeng Zhao and published by Frontiers Media SA. This book was released on 2020-07-28 with total page 130 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Functional Polymers for Controlled Drug Release written by Umile Gianfranco Spizzirri and published by MDPI. This book was released on 2020-03-19 with total page 204 pages. Available in PDF, EPUB and Kindle. Book excerpt: This Special Issue focuses on the synthesis and characterization of hydrogels specifically used as carriers of biological molecules for pharmaceutical and biomedical employments. Pharmaceutical applications of hydrophilic materials has emerged as one of the most significant trends in the area of nanotechnology. To propose some of the latest findings in this field, each contribution involves an in-depth analysis including different starting materials and their physico-chemical and biological properties with the aim of synthetizing high-performing devices for specific use. In this context, intelligent polymeric devices able to be morphologically modified in response to an internal or external stimulus, such as pH or temperature, have been actively pursued. In general, hydrophilic polymeric materials lead to high in vitro and/or in vivo therapeutic efficacy, with programmed site-specific feature showing remarkable potential for targeted therapy. This Special Issue serves to highlight and capture the contemporary progress in this field. Relevant resources and people to approach - American Association Pharmaceutical Scientists (AAPS): web: www.aaps.org; email: (marketing division): [email protected]; (mmeting division): [email protected] - International Association for Pharmaceutical Technology (APV): web: apv-mainz.de; email (managing director): [email protected]; (congresses and trade fairs): [email protected] - International Society of Drug Delivery Sciences and Technology (APGI): web: http://www.apgi.org; email: [email protected]; - The Society of Chemical Industry (SCI): web: www.soci.org; email: [email protected] - Italian society of researchers in pharmaceutical technology (A.D.R.I.T.E.L.F.): web: www-3.unipv.it/adritelf/; email (head): [email protected]; - Italian Chemical Society (SCI): web: www.soc.chim.it; email: [email protected] - Associazione Farmaceutici Industria (AFI): web: http://www.afiweb.it; email:: [email protected] - Società Italiana di Chimica e Scienze Cosmetologiche (SICC): web: www.sicc.tv; mail: [email protected] - Society for biomaterials: web: www.biomaterials.org; email: [email protected] - European Society for Biomaterials (ESB): web: www.esbiomaterials.eu; email: - Società Italiana Biomateriali (SIB): web: www.biomateriali.org; email: [email protected] - Medical Device Manufactures Association (MDMA): web: www.medicaldevices.org; - European Polymer Federaton (EPF): web: www.europolyfed.org; email: [email protected] - Society of Plastics Engineers (SPE): web: www.4spe.org; email: [email protected] - Polymer Processing Society (PPS): web: www.poly-eng.uakron.edu/pps/; email: [email protected]; - American Chinese Pharmaceutical Association; web: www.acpa-rx.org; - Chinese Pharmaceutical Association: web: www.pharmachinaonline.com - Society of Polymer Science, Japan: web: www.spsj.or.jp; email: [email protected]
Download or read book Functional Chitosan written by Sougata Jana and published by Springer Nature. This book was released on 2020-03-05 with total page 489 pages. Available in PDF, EPUB and Kindle. Book excerpt: Thanks to their unique properties, chitosan and chitosan-based materials have numerous applications in the field of biomedicine, especially in drug delivery. This book examines biomedical applications of functional chitosan, exploring the various functions and applications in the development of chitosan-based biomaterials. It also describes the chemical structure of chitosan and discusses the relationship between their structure and functions, providing a theoretical basis for the design of biomaterials. Lastly, it reviews chemically modified and composite materials of chitin and chitosan derivatives for biomedical applications, such as tissue engineering, nanomedicine, drug delivery, and gene delivery.
Download or read book Multifunctional Medical Devices Based on PH sensitive Hydrogels for Controlled Drug Delivery written by Hongyan He and published by . This book was released on 2006 with total page 198 pages. Available in PDF, EPUB and Kindle. Book excerpt: Abstract: Hydrogels are a desired material for biomedical and pharmaceutical applications due to their unique swelling properties and highly hydrated structure. To better control the synthesized hydrogels for various applications, it is necessary to have a thorough understanding of hydrogel structure and reaction mechanism. In this study, pH-sensitive hydrogel networks consisting of methacrylic acid (MAA) crosslinked with tri(ethylene glycol) dimethacrylate (TEGDMA) were synthesized by free-radical photopolymerization in the water/ethanol mixture with different ratios under various light intensity. Reaction rate was measured using Photo-Differential Scanning Calorimetry (PhotoDSC) with a modified sample pan designed for handling volatile reagents. A photo-rheometer and a dynamic light scattering (DLS) goniometer were used to follow the changes in viscosity and molecule size of the resin system during photopolymerization. By using the desired functional hydrogels, several drug delivery systems were developed based on the selected integration of a number of micro-manufacturing modules such as soft-lithography, micro-imprinting, and polymer self-folding, to achieve multi-functionalities such as drug protection, self-regulated oscillatory release, enhanced mucoadhesion, and targeted unidirectional release. To evaluate the device performance, adhesion measurement, dynamic flow testing, and targeted unidirectional release were conducted for trans-luminal delivery of two model drugs, acid orange 8 and bovine serum albumin. The self-folding device first attached to the mucosal surface and then curled into the mucus, leading to enhanced mucoadhesion in the mode of "grabbing". Furthermore, the folded layer served as a diffusion barrier, minimizing the drug leakage in the small intestine. The resulting unidirectional release provides improved drug transport through the mucosal epithelium due to localized high drug concentration. The functionalities of the devices have been successfully demonstrated in vitro using a porcine small intestine. The novel delivery devices will be of great benefit to the advancement of oral administration of proteins and DNAs. Since the mucus layer covers many tissues at other specific sites, the devices may be applied for ocular, buccal, vaginal and rectal administrations. The polymer self-folding at the microscale can also be applied as probe arrays for bio/chemical sensing, carriers in cell-based bioreactors, and tissue clamping.
Download or read book Biodegradable Hydrogels for Drug Delivery written by Haesun Park and published by CRC Press. This book was released on 2011-07-08 with total page 272 pages. Available in PDF, EPUB and Kindle. Book excerpt: From the Authors' Preface The advances made in the area of controlled drug delivery during the last two decades are remarkable ....Of the many polymeric materials, biodegradable hydrogels present unique advantages and opportunities in the development of ...delivery devices....We have undertaken the challenge of putting together information relevant to biodegradable hydrogels in one place. This book covers the mechanisms of biodegradation, types of biodegradable hydrogels,chemical and physical gels, chemical and enzymatic degradation, and examples of biodegradable drug delivery systems.
Download or read book Intelligent Hydrogels in Diagnostics and Therapeutics written by Anujit Ghosal and published by CRC Press. This book was released on 2020-05-27 with total page 164 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book explores the potential of hydrogels as a multiutility system and their benefits (biocompatibility, degradability, and supporting scaffolds) for a wide range of applications in diagnostics and therapeutics. It also discusses the future prospects and challenges facing hydrogels. A wide variety of smart hydrogels (conducting, stimuli responsive, and others) with possible biomedical applications are elaborated. The book demonstrates the effectiveness of hydrogels in diagnostics of diseases in various in vivo and in vitro environments and highlights the engineering/functionalization of hydrogels for everyday drug dosage as an efficient drug carrier, scaffold, and sensing application. Explores the potential of hydrogels as a multifunctional system and their benefits, particularly for biomedical applications in diagnostics as well as therapeutics. Highlights the designing and engineering of hydrogels for everyday drug dosage and possible functionalization to fabricate an efficient drug carrier. Examines the significance of biopolymer-based hydrogels and their responsiveness in different physiological fluids. Demonstrates the effectiveness of hydrogels in diagnostics of diseases in various in,vivo and in,vitro environments. Presents challenges associated with the hydrogels and discusses possible in-hand modifications at length. Dr. Anujit Ghosal worked in the School of Biotechnology, Jawaharlal Nehru University, India. Currently, he is affiliated with the School of Life Sciences, Beijing Institute of Technology, Beijing, PRC. Dr. Ghosal researches in biochemistry, polymer chemistry, and nanotechnology. He has been the recipient of prestigious fellowships throughout his research career. His research ability is proven by his published peer-reviewed research and review articles and contributed book chapters. Dr. Ajeet Kaushik works as an assistant professor of chemistry and is exploring advanced electrochemical sensing systems and nanomedicine for personalized health wellness at the Department of Natural Sciences of the Division of Science, Arts, and Mathematics at Florida Polytechnic University, Lakeland, US. He is the recipient of various reputed awards for his service in the area of nanobiotechnology for health care. His excellent research credentials are reflected by his four edited books, 100 international research peer-reviewed publications, and three patents in the area of nanomedicine and smart biosensors for personalized health care.
Download or read book Hydrogels written by Thakur Raghu Raj Singh and published by CRC Press. This book was released on 2018-02-28 with total page 353 pages. Available in PDF, EPUB and Kindle. Book excerpt: Hydrogels are crosslinked, macromolecular polymeric materials arranged in a three-dimensional network, which can absorb and retain large amounts of water. Hydrogels are commonly used in clinical practice and experimental medicine for a wide range of applications, including drug delivery, tissue engineering and regenerative medicine, diagnostics, cellular immobilization, separation of biomolecules or cells, and barrier materials to regulate biological adhesions. This book elucidates the underlying concepts and emerging applications of hydrogels and will provide key case studies and critical analysis of the existing research.
Download or read book Polymeric Gels written by Kunal Pal and published by Woodhead Publishing. This book was released on 2018-06-15 with total page 568 pages. Available in PDF, EPUB and Kindle. Book excerpt: Polymeric Gels: Characterization, Properties and Biomedical Applications covers the fundamentals and applications of polymeric gels. Particular emphasis is given to their synthesis, properties and characteristics, with topics such as natural, synthetic, and smart polymeric gels, medical applications, and advancements in conductive and magnetic gels presented. The book covers the basics and applications of hydrogels, providing readers with a comprehensive guide on the types of polymeric gels used in the field of biomedical engineering. Provides guidance for decisions on the suitability and appropriateness of a synthetic route and characterization technique for particular polymeric networks Analyzes and compares experimental data Presents in-depth information on the physical properties of polymeric gels using mathematical models Uses an interdisciplinary approach to discuss potential new applications for both established polymeric gels and recent advances
Download or read book Hydrogels in Medicine and Pharmacy written by Nikolaos A. Peppas and published by CRC Press. This book was released on 2019-08-15 with total page 191 pages. Available in PDF, EPUB and Kindle. Book excerpt: First Published in 1986, this book offers a full, comprehensive guide to the application of hydrogels in medicine. Carefully compiled and filled with a vast repertoire of notes, diagrams, and references this book serves as a useful reference for students of medicine and other practitioners in their respective fields.
Download or read book Biomedical Applications of Hydrogels Handbook written by Raphael M. Ottenbrite and published by Springer Science & Business Media. This book was released on 2010-09-05 with total page 438 pages. Available in PDF, EPUB and Kindle. Book excerpt: Hydrogels are networks of polymer chains which can produce a colloidal gel containing over 99 per cent water. The superabsorbency and permeability of naturally occurring and synthetic hydrogels give this class of materials an amazing array of uses. These uses range from wound dressings and skin grafts to oxygen-permeable contact lenses to biodegradable delivery systems for drugs or pesticides and scaffolds for tissue engineering and regenerative medicine. Biomedical Applications of Hydrogels Handbook provides a comprehensive description of this diverse class of materials, covering both synthesis and properties and a broad range of research and commercial applications. The Handbook is divided into four sections: Stimuli-Sensitive Hydrogels, Hydrogels for Drug Delivery, Hydrogels for Tissue Engineering, and Hydrogels with Unique Properties. Key Features: Provides comprehensive coverage of the basic science and applications of a diverse class of materials Includes both naturally occurring and synthetic hydrogels Edited and written by world leaders in the field.
Download or read book Functional Polymers for Controlled Drug Release written by Umile Gianfranco Spizzirri and published by . This book was released on 2020 with total page 204 pages. Available in PDF, EPUB and Kindle. Book excerpt: This Special Issue focuses on the synthesis and characterization of hydrogels specifically used as carriers of biological molecules for pharmaceutical and biomedical employments. Pharmaceutical applications of hydrophilic materials has emerged as one of the most significant trends in the area of nanotechnology. To propose some of the latest findings in this field, each contribution involves an in-depth analysis including different starting materials and their physico-chemical and biological properties with the aim of synthetizing high-performing devices for specific use. In this context, intelligent polymeric devices able to be morphologically modified in response to an internal or external stimulus, such as pH or temperature, have been actively pursued. In general, hydrophilic polymeric materials lead to high in vitro and/or in vivo therapeutic efficacy, with programmed site-specific feature showing remarkable potential for targeted therapy. This Special Issue serves to highlight and capture the contemporary progress in this field. Relevant resources and people to approach - American Association Pharmaceutical Scientists (AAPS): web: www.aaps.org; email: (marketing division): [email protected]; (mmeting division): [email protected] - International Association for Pharmaceutical Technology (APV): web: apv-mainz.de; email (managing director).
Download or read book Hydrogels written by Thakur Raghu Raj Singh and published by CRC Press. This book was released on 2018-02-28 with total page 289 pages. Available in PDF, EPUB and Kindle. Book excerpt: Hydrogels are crosslinked, macromolecular polymeric materials arranged in a three-dimensional network, which can absorb and retain large amounts of water. Hydrogels are commonly used in clinical practice and experimental medicine for a wide range of applications, including drug delivery, tissue engineering and regenerative medicine, diagnostics, cellular immobilization, separation of biomolecules or cells, and barrier materials to regulate biological adhesions. This book elucidates the underlying concepts and emerging applications of hydrogels and will provide key case studies and critical analysis of the existing research.
Download or read book Hydrogels written by Lacramioara Popa and published by BoD – Books on Demand. This book was released on 2019-04-10 with total page 133 pages. Available in PDF, EPUB and Kindle. Book excerpt: Hydrogels, as three-dimensional polymer networks, are able to retain a large amount of water in their swollen state. The biomedical application of hydrogels was initially hampered by the toxicity of cross-linking agents and the limitations of hydrogel formation under physiological conditions. However, emerging knowledge in polymer chemistry and an increased understanding of biological processes have resulted in the design of versatile materials and minimally invasive therapies.The novel but challenging properties of hydrogels are attracting the attention of researchers in the biological, medical, and pharmaceutical fields. In the last few years, new methods have been developed for the preparation of hydrophilic polymers and hydrogels, which may be used in future biomedical and drug delivery applications. Such efforts include the synthesis of self-organized nanostructures based on triblock copolymers with applications in controlled drug delivery. These hydrogels could be used as carriers for drug delivery when combined with the techniques of drug imprinting and subsequent release. Engineered protein hydrogels have many potential advantages. They are excellent biomaterials and biodegradables. Furthermore, they could encapsulate drugs and be used in injectable forms to replace surgery, to repair damaged cartilage, in regenerative medicine, or in tissue engineering. Also, they have potential applications in gene therapy, although this field is relatively new.
Download or read book Plant and Algal Hydrogels for Drug Delivery and Regenerative Medicine written by Tapan Kumar Giri and published by Woodhead Publishing. This book was released on 2021-06-12 with total page 592 pages. Available in PDF, EPUB and Kindle. Book excerpt: Plant and Algal Hydrogels for Drug Delivery and Regenerative Medicine offers a materials-focused and systematic overview of biopolymeric hydrogels utilized for biomedical applications. The book details the synthesis and characterization of plant and algal-based hydrogels, with each chapter addressing a separate polysaccharide hydrogel type. Specific applications in drug delivery and regenerative medicine are also discussed, highlighting the efficacy, biocompatibility, benefits and challenges for each polysaccharide hydrogel subtype. There is increasing demand for biomaterials which reduce/prevent the host response, inflammation and rejection, hence this book provides a timely resource. Biopolymeric hydrogels have skyrocketed because of their necessity in in vivo applications. They create an environment similar to living tissue, which is both biocompatible and biodegradable. Plant and algal polysaccharides in particular are well-equipped with functional groups that are easily modified for beneficial results. Systematically covers each plant and algal polysaccharide hydrogel subtype, from starch-based hydrogels to pectin and alginate-based hydrogels Provides an end-to-end description of the synthesis, characterization and application of biopolymeric hydrogels for drug delivery and regenerative medicine Appeals to a diverse readership, including those in biomedicine, pharmacy, polymer chemistry, biochemistry, materials science, biomedical engineering, and other biotechnology related disciplines