Download or read book From Sanderson s to Alley s written by Charles W. Parton and published by Charles William Parton. This book was released on 1992 with total page 196 pages. Available in PDF, EPUB and Kindle. Book excerpt: In the guise of telling the story of Alley's, the author has also illuminated island history and the unsettling but inevitable process of change.
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Download or read book Lloyd s Register of Shipping 1889 written by Lloyd's Register Foundation and published by Lloyd's Register . This book was released on 1889-01-01 with total page 1799 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Lloyd's Register of Shipping records the details of merchant vessels over 100 gross tonnes, which are self-propelled and sea-going, regardless of classification. Before the time, only those vessels classed by Lloyd's Register were listed. Vessels are listed alphabetically by their current name.
Download or read book The Boston Directory for the Year 1852 written by and published by . This book was released on 1852 with total page 448 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Official Report of the Debates and Proceedings in the State Convention Assembled May 4th 1853 to Revise and Amend the Constitution of the Commonwealth of Massachusetts written by Massachusetts. Constitutional Convention and published by . This book was released on 1853 with total page 1398 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Records of the Massachusetts volunteer militia called out by the Governor of Massachusetts to suppress a threatened invasion during the war of 1812 14 written by Massachusetts Adjutant General's Office and published by Dalcassian Publishing Company. This book was released on 1913-01-01 with total page 472 pages. Available in PDF, EPUB and Kindle. Book excerpt:
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Download or read book Sacramento City and County Directory for 1868 written by Robert E. Draper and published by BoD – Books on Demand. This book was released on 2022-06-06 with total page 330 pages. Available in PDF, EPUB and Kindle. Book excerpt: Reprint of the original, first published in 1868.
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Download or read book Official report of the debates and proceedings written by Massachusetts constitutional convention, 1853 and published by . This book was released on 1853 with total page 814 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Cytotoxic Payloads for AntibodyDrug Conjugates written by David E Thurston and published by Royal Society of Chemistry. This book was released on 2019-07-11 with total page 502 pages. Available in PDF, EPUB and Kindle. Book excerpt: Antibody–drug conjugates (ADCs) represent one of the most promising and exciting areas of anticancer drug discovery. Five ADCs are now approved in the US and EU [i.e., ado-trastuzumab emtansine (KadcylaTM), brentuximab vedotin (AdcetrisTM), inotuzumab ozogamicin (BesponsaTM), gemtuzumab ozogamicin (MylotargTM) and moxetumomab pasudotox-tdfk (Lumoxiti®)] and over 70 others are in various stages of clinical development, with impressive interim results being reported for many. The technology is based on the concept of delivering a cytotoxic payload selectively to cancer cells by attaching it to an antibody targeted to antigens on the cell surfaces. This approach has several advantages including the ability to select patients as likely responders based on the presence of antigen on the surface of their cancer cells and a wider therapeutic index, given that ADC targeting enables a more efficient delivery of cytotoxic agents to cancer cells than can be achieved by conventional chemotherapy, thus minimising systemic toxicity. Although there are many examples of antibodies that have been developed for this purpose, along with numerous linker technologies used to attach the cytotoxic agent to the antibody, there is presently a relatively small number of payload molecules in clinical use. The purpose of this book is to describe the variety of payloads used to date, along with a discussion of their advantages and disadvantages and to provide information on novel payloads at the research stage that may be used clinically in the future.
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Download or read book Biosimilars of Monoclonal Antibodies written by Cheng Liu and published by John Wiley & Sons. This book was released on 2016-12-12 with total page 645 pages. Available in PDF, EPUB and Kindle. Book excerpt: Addressing a significant need by describing the science and process involved to develop biosimilars of monoclonal antibody (mAb) drugs, this book covers all aspects of biosimilar development: preclinical, clinical, regulatory, manufacturing. • Guides readers through the complex landscape involved with developing biosimilar versions of monoclonal antibody (mAb) drugs • Features flow charts, tables, and figures that clearly illustrate processes and makes the book comprehensible and accessible • Includes a review of FDA-approved mAb drugs as a quick reference to facts and useful information • Examines new technologies and strategies for improving biosimilar mAbs
Download or read book L Z written by London (England). Merchant Taylors' School and published by . This book was released on 1936 with total page 698 pages. Available in PDF, EPUB and Kindle. Book excerpt:
