Download or read book First Hitting Time Regression Models written by Chrysseis Caroni and published by John Wiley & Sons. This book was released on 2017-07-19 with total page 206 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book aims to promote regression methods for analyzing lifetime (or time-to-event) data that are based on a representation of the underlying process, and are therefore likely to offer greater scientific insight compared to purely empirical methods. In contrast to the rich statistical literature, the regression methods actually employed in lifetime data analysis are limited, particularly in the biomedical field where D. R. Cox’s famous semi-parametric proportional hazards model predominates. Practitioners should become familiar with more flexible models. The first hitting time regression models (or threshold regression) presented here represent observed events as the outcome of an underlying stochastic process. One example is death occurring when the patient’s health status falls to zero, but the idea has wide applicability – in biology, engineering, banking and finance, and elsewhere. The central topic is the model based on an underlying Wiener process, leading to lifetimes following the inverse Gaussian distribution. Introducing time-varying covariates and many other extensions are considered. Various applications are presented in detail.

Download or read book Theory and Practice of Risk Assessment written by Christos P. Kitsos and published by Springer. This book was released on 2015-05-18 with total page 414 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book covers the latest results in the field of risk analysis. Presented topics include probabilistic models in cancer research, models and methods in longevity, epidemiology of cancer risk, engineering reliability and economical risk problems. The contributions of this volume originate from the 5th International Conference on Risk Analysis (ICRA 5). The conference brought together researchers and practitioners working in the field of risk analysis in order to present new theoretical and computational methods with applications in biology, environmental sciences, public health, economics and finance.

Download or read book Demography of Population Health Aging and Health Expenditures written by Christos H. Skiadas and published by Springer Nature. This book was released on 2020-08-24 with total page 448 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book provides theoretical and applied material for estimating vital parts of demography and health issues including the healthy aging process along with calculating the healthy life years lost to disability. It further includes the appropriate methodology for the optimum health expenditure allocation. Through providing data analysis, statistical and stochastic methodology, probability approach and important applications, the book explores topics such as aging and mortality, birth-death processes, self-perceived age, life-time and survival as well as pension and labor-force. By providing a methodological approach to health problems in demography and society including and quantifying important parameters, this book is a valuable guide for researchers, theoreticians and practitioners from various disciplines.

Download or read book Mathematical and Statistical Models and Methods in Reliability written by V.V. Rykov and published by Springer Science & Business Media. This book was released on 2010-11-02 with total page 465 pages. Available in PDF, EPUB and Kindle. Book excerpt: The book is a selection of invited chapters, all of which deal with various aspects of mathematical and statistical models and methods in reliability. Written by renowned experts in the field of reliability, the contributions cover a wide range of applications, reflecting recent developments in areas such as survival analysis, aging, lifetime data analysis, artificial intelligence, medicine, carcinogenesis studies, nuclear power, financial modeling, aircraft engineering, quality control, and transportation. Mathematical and Statistical Models and Methods in Reliability is an excellent reference text for researchers and practitioners in applied probability and statistics, industrial statistics, engineering, medicine, finance, transportation, the oil and gas industry, and artificial intelligence.

Download or read book Regression Modeling of Time to Event Data Using the Ornstein Uhlenbeck Process written by Roger Alan Erich and published by . This book was released on 2012 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt: Abstract: In this research, we develop innovative regression models for survival analysis that model time to event data using a latent health process which stabilizes around an equilibrium point; a characteristic often observed in biological systems. Regression modeling in survival analysis is typically accomplished using Cox regression, which requires the assumption of proportional hazards. An alternative model, which does not require proportional hazards, is the First Hitting Time (FHT) model where a subject's health is modeled using a latent stochastic process. In this modeling framework, an event occurs once the process hits a predetermined boundary. The parameters of the process are related to covariates through generalized link functions thereby providing regression coefficients with clinically meaningful interpretations. In this dissertation, we present an FHT model based on the Ornstein-Uhlenbeck (OU) process; a modified Wiener process which drifts from the starting value of the process toward a state of equilibrium or homeostasis present in many biological applications. We extend previous OU process models to allow the process to change according to covariate values. We also discuss extensions of our methodology to include random effects accounting for unmeasured covariates. In addition, we present a mixture model with a cure rate using the OU process to model the latent health status of those subjects susceptible to experiencing the event under study. We apply these methods to survival data collected on melanoma patients and to another survival data set pertaining to carcinoma of the oropharynx.

Download or read book Semi parametric Survival Analysis Via Dirichlet Process Mixtures of the First Hitting Time Model written by Jonathan A. Race and published by . This book was released on 2019 with total page 149 pages. Available in PDF, EPUB and Kindle. Book excerpt: Time-to-event data often violate the proportional hazards assumption inherent in the popular Cox regression model. Such violations are especially common in the sphere of biological and medical data where latent heterogeneity due to unmeasured covariates or time varying effects are common. A variety of parametric survival models have been proposed which make more appropriate assumptions on the hazard function, at least for certain applications. One such model is derived from the First Hitting Time (FHT) paradigm which assumes that a subject's event time is determined by a latent stochastic process reaching a threshold value. Several random effects specifications of the FHT model have also been proposed which allow for better modeling of data with unmeasured covariates. While often appropriate, these methods often display limited flexibility due to their inability to model a wide range of heterogeneities. To address this issue, we propose two Bayesian models which loosen assumptions on the mixing distribution inherent in the random effects FHT models currently in use. The first proposed model is ideally suited for standard regression analyses. The second model is designed for use in clinical trials where survival is the outcome of interest. We demonstrate via simulation study that the proposed models greatly improve both survival and parameter estimation in the presence of latent heterogeneity. We also apply the proposed methodologies to data from a toxicology/carcinogenicity study which exhibits nonproportional hazards and contrast the results with competing methods.

Download or read book Predictions in Time Series Using Regression Models written by Cory Terrell and published by Scientific e-Resources. This book was released on 2019-09-02 with total page 300 pages. Available in PDF, EPUB and Kindle. Book excerpt: Regression methods have been a necessary piece of time arrangement investigation for over a century. As of late, new advancements have made real walks in such territories as non-constant information where a direct model isn't fitting. This book acquaints the peruser with fresher improvements and more assorted regression models and methods for time arrangement examination. Open to any individual who knows about the fundamental present day ideas of factual deduction, Regression Models for Time Series Analysis gives a truly necessary examination of late measurable advancements. Essential among them is the imperative class of models known as summed up straight models (GLM) which gives, under a few conditions, a bound together regression hypothesis reasonable for constant, all out, and check information. The creators stretch out GLM methodology deliberately to time arrangement where the essential and covariate information are both arbitrary and stochastically reliant. They acquaint readers with different regression models created amid the most recent thirty years or somewhere in the vicinity and condense traditional and later outcomes concerning state space models.

Download or read book Applied Regression Analysis written by Norman R. Draper and published by John Wiley & Sons. This book was released on 1998-04-23 with total page 736 pages. Available in PDF, EPUB and Kindle. Book excerpt: Ein Hauptziel wissenschaftlicher Forschung ist das Auffinden von Beziehungen zwischen Variablen. Die Regressionsrechnung ist ein allgemein gebräuchliches statistisches Mittel zur Erstellung von mathematischen Modellen aus Forschungsdaten. Die 3. Auflage wurde um 16 neue Kapitel erweitert; die Grundlagen der Regressionsrechnung werden, ausgehend von klassischen Konzepten, präzise erklärt. Mit vielen Übungsaufgaben und Lösungen sowie einer Diskette. (06/98)

Download or read book Encyclopedia of Quantitative Risk Analysis and Assessment written by and published by Wiley. This book was released on 2008-09-02 with total page 516 pages. Available in PDF, EPUB and Kindle. Book excerpt: Leading the way in this field, the Encyclopedia of Quantitative Risk Analysis and Assessment is the first publication to offer a modern, comprehensive and in-depth resource to the huge variety of disciplines involved. A truly international work, its coverage ranges across risk issues pertinent to life scientists, engineers, policy makers, healthcare professionals, the finance industry, the military and practising statisticians. Drawing on the expertise of world-renowned authors and editors in this field this title provides up-to-date material on drug safety, investment theory, public policy applications, transportation safety, public perception of risk, epidemiological risk, national defence and security, critical infrastructure, and program management. This major publication is easily accessible for all those involved in the field of risk assessment and analysis. For ease-of-use it is available in print and online.

Download or read book Predictions in Time Series Using Regression Models written by Frantisek Stulajter and published by Springer Science & Business Media. This book was released on 2013-06-29 with total page 237 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book will interest and assist people who are dealing with the problems of predictions of time series in higher education and research. It will greatly assist people who apply time series theory to practical problems in their work and also serve as a textbook for postgraduate students in statistics economics and related subjects.

Download or read book Current Index to Statistics Applications Methods and Theory written by and published by . This book was released on 1989 with total page 832 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Current Index to Statistics (CIS) is a bibliographic index of publications in statistics, probability, and related fields.

Download or read book Statistical Theory and Method Abstracts written by and published by . This book was released on 1998 with total page 744 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Considering Time as the Random Variable written by Gilles O. Zumbach and published by . This book was released on 1998 with total page 10 pages. Available in PDF, EPUB and Kindle. Book excerpt: The usual point of view when analyzing time series is to consider quantities for a given fixed time interval. Yet, one can adopt the opposite point of view, namely that the quantity is fixed and the time interval is the random variable of interest. This reverted point of view leads us to study the first hitting time and the first exit time. We are studying the probability density P( t | r), that a given return r is reached for the first time after an elapsed time t. This probability density is being computed for the FX market, for a Garch(1,1) process and for a Gaussian random walk. In particular, this study is showing the region in which the probability density does not scale and exemplify the large event region.

Download or read book An Introduction to Stochastic Modeling written by Howard M. Taylor and published by Academic Press. This book was released on 2014-05-10 with total page 410 pages. Available in PDF, EPUB and Kindle. Book excerpt: An Introduction to Stochastic Modeling provides information pertinent to the standard concepts and methods of stochastic modeling. This book presents the rich diversity of applications of stochastic processes in the sciences. Organized into nine chapters, this book begins with an overview of diverse types of stochastic models, which predicts a set of possible outcomes weighed by their likelihoods or probabilities. This text then provides exercises in the applications of simple stochastic analysis to appropriate problems. Other chapters consider the study of general functions of independent, identically distributed, nonnegative random variables representing the successive intervals between renewals. This book discusses as well the numerous examples of Markov branching processes that arise naturally in various scientific disciplines. The final chapter deals with queueing models, which aid the design process by predicting system performance. This book is a valuable resource for students of engineering and management science. Engineers will also find this book useful.

Download or read book Probability and Bayesian Modeling written by Jim Albert and published by CRC Press. This book was released on 2019-12-06 with total page 553 pages. Available in PDF, EPUB and Kindle. Book excerpt: Probability and Bayesian Modeling is an introduction to probability and Bayesian thinking for undergraduate students with a calculus background. The first part of the book provides a broad view of probability including foundations, conditional probability, discrete and continuous distributions, and joint distributions. Statistical inference is presented completely from a Bayesian perspective. The text introduces inference and prediction for a single proportion and a single mean from Normal sampling. After fundamentals of Markov Chain Monte Carlo algorithms are introduced, Bayesian inference is described for hierarchical and regression models including logistic regression. The book presents several case studies motivated by some historical Bayesian studies and the authors’ research. This text reflects modern Bayesian statistical practice. Simulation is introduced in all the probability chapters and extensively used in the Bayesian material to simulate from the posterior and predictive distributions. One chapter describes the basic tenets of Metropolis and Gibbs sampling algorithms; however several chapters introduce the fundamentals of Bayesian inference for conjugate priors to deepen understanding. Strategies for constructing prior distributions are described in situations when one has substantial prior information and for cases where one has weak prior knowledge. One chapter introduces hierarchical Bayesian modeling as a practical way of combining data from different groups. There is an extensive discussion of Bayesian regression models including the construction of informative priors, inference about functions of the parameters of interest, prediction, and model selection. The text uses JAGS (Just Another Gibbs Sampler) as a general-purpose computational method for simulating from posterior distributions for a variety of Bayesian models. An R package ProbBayes is available containing all of the book datasets and special functions for illustrating concepts from the book. A complete solutions manual is available for instructors who adopt the book in the Additional Resources section.

Download or read book Statistical Models written by Source Wikipedia and published by University-Press.org. This book was released on 2013-09 with total page 108 pages. Available in PDF, EPUB and Kindle. Book excerpt: Please note that the content of this book primarily consists of articles available from Wikipedia or other free sources online. Pages: 107. Chapters: Markov chain, Stochastic process, Statistical model, Power law, Linear model, Bayesian network, Mixture model, Item response theory, Discrete choice, Random walk, Predictive analytics, Errors-in-variables models, Rasch model, Rubin causal model, Generalized linear model, Restricted randomization, Directional statistics, Mediation, Total least squares, Cumulative frequency analysis, Generalized additive model for location, scale and shape, Common-cause and special-cause, Proportional hazards models, Independent component analysis, Mixed logit, Parametric model, Regression dilution, Classical test theory, Boolean analysis, Power transform, Segmented regression, Graphical model, Predictive modelling, Generalizability theory, Neighbourhood components analysis, Time-frequency representation, Population modeling, Regression model validation, Completely randomized design, Random effects model, Econometric model, Multilevel model, Generalized estimating equation, Independent and identically distributed random variables, Latent variable, Model selection, Stationary subspace analysis, Threshold model, Local independence, Rasch model estimation, Semiparametric model, Statistical interference, First-hitting-time model, Generative model, Moderation, Dummy variable, Latent variable model, Log-linear modeling, Rare disease assumption, Hierarchical linear modeling, Function approximation, Observational equivalence, Doubly stochastic model, Latent growth modeling, Exponential dispersion model, Marginal model, Epitome, Continuum structure function, Reification, Multinomial probit.

Download or read book Lifetime Data Models in Reliability and Survival Analysis written by Nicholas P. Jewell and published by Springer Science & Business Media. This book was released on 2013-04-17 with total page 392 pages. Available in PDF, EPUB and Kindle. Book excerpt: Statistical models and methods for lifetime and other time-to-event data are widely used in many fields, including medicine, the environmental sciences, actuarial science, engineering, economics, management, and the social sciences. For example, closely related statistical methods have been applied to the study of the incubation period of diseases such as AIDS, the remission time of cancers, life tables, the time-to-failure of engineering systems, employment duration, and the length of marriages. This volume contains a selection of papers based on the 1994 International Research Conference on Lifetime Data Models in Reliability and Survival Analysis, held at Harvard University. The conference brought together a varied group of researchers and practitioners to advance and promote statistical science in the many fields that deal with lifetime and other time-to-event-data. The volume illustrates the depth and diversity of the field. A few of the authors have published their conference presentations in the new journal Lifetime Data Analysis (Kluwer Academic Publishers).