Download or read book First Conference on DNA Topoisomerases in Cancer Chemotherapy written by and published by . This book was released on 1987 with total page 164 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book First Conference on DNA Topoisomerases in Cancer Chemotherapy written by and published by . This book was released on 1987 with total page 149 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book DNA Topoisomerases in Cancer Therapy written by Toshiwo Andoh and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 208 pages. Available in PDF, EPUB and Kindle. Book excerpt: In the mid 80's type I and II enzymes were found to be the intracellular targets of a number of efficacious anticancer drugs such as doxorubicin, mitoxantrone, etoposide and camptothecin as a result of a continued efforts of many investigators, especially Leroy Liu and his collaborators at Johns Hopkins University. Readers will find a series of chapters written by researchers actively engaged in the expanding field of topoisomerase and their inhibitors. The series of chapters cover review articles on pharmacology and the molecular mechanism of topoisomerase I- and II-targeting anticancer drugs in mammals and in the yeast Saccharomyces cerevisiae, which has proved to be a superb model organism for studies of anticancer drugs. This volume compiles up-to-date information on the topoisomerase-targeting compounds in clinical and preclinical development as a useful and important reference book for students and researchers in the field of pharmacology, toxicology, oncology and molecular biology.
Download or read book First Conference on DNA Topoisomerases in Cancer Chemotherapy written by and published by . This book was released on 1987 with total page 162 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book DNA Topoisomerases and Cancer written by and published by . This book was released on 2011-09-21 with total page 456 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book DNA Topoisomerases in Cancer written by Milan Potmesil and published by Oxford University Press, USA. This book was released on 1991 with total page 364 pages. Available in PDF, EPUB and Kindle. Book excerpt: DNA Topoisomerases are a unique class of enzymes that are responsible for the control and modification of DNA topology (tertiary structure); one example of their function is the transformation of chromosomes from a supercoiled condensed state to uncoiled strands and vice versa. They are of interest both for their intrinsic role in cell biology (i.e. control of cell division) and also because some anticancer drugs, such as camptothecin, act by inhibiting their action.
Download or read book NCI Monographs written by and published by . This book was released on 1987 with total page 436 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Cumulated Index Medicus written by and published by . This book was released on 1987 with total page 1252 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Nuclear Structure and Function written by I.B. Zbarsky and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 479 pages. Available in PDF, EPUB and Kindle. Book excerpt: This collection of 101 short communications, submitted by some of the participants at the 11th Nuclear Workshop held in Suzdal, USSR, 18-23 September, 1989, provides a representative survey of the material presented at the Workshop. Articles have been submitted by both those who delivered lectures and those who had poster presentations. The order of presentation at the Nuclear Workshop is roughly maintained within this proceedings book, but the session titles within the scientific program have not been utilized as discrete subdivisions within the book, because of the considerable overlap of subject matter. The overall sequence is as follows: Genome structure, Gene Structure and Expression, Nucleolar Genes, Structure and Proteins, Chromatin and Nuclear Granules, Nuclear Matrix and Nuclear Proteins, Replication and Transcription and finally Nuclear Envelope and Nuclear Cytoplasmic Transport. Several articles on Nuclear Lipids are also included, stemming from an evening round-table discussion on lipids. The third Wilhelm Bernhard Lecture was delivered in Suzdal by Professor Harris Busch, who can be seen in the photograph above (on the left) in the presence of Professor Ilya B. Zbarsky, President of the organizing committee for the 11th Nuclear Workshop. (Previous Wilhelm Bernhard lecturers have been Ronald H. Reeder, in Krakow, Poland, 1985 and Oscar L. Miller, Jr. , in Stevensbeek, The Netherlands, in 1987).
Download or read book Current Catalog written by National Library of Medicine (U.S.) and published by . This book was released on with total page 782 pages. Available in PDF, EPUB and Kindle. Book excerpt: First multi-year cumulation covers six years: 1965-70.
Download or read book Journal of the National Cancer Institute written by and published by . This book was released on 1996 with total page 1074 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Scientific Information Services of the National Cancer Institute written by National Institutes of Health (U.S.) and published by . This book was released on 1987 with total page 40 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Monthly Catalog of United States Government Publications written by and published by . This book was released on with total page 1110 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Recent Reviews written by and published by . This book was released on 1988 with total page 124 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book The 4 Quinolones Anti Bacterial Agents in Vitro written by Geoff C. Crumplin and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 282 pages. Available in PDF, EPUB and Kindle. Book excerpt: The 4-quinolone antibacterial agents have been under development and in use for over 25 years, but despite an enormous body of research work there are still many basic questions that remain unanswered. For example, we do not know how these agents kill susceptible cells - or even how the drugs interact with the target mol- ecule(s). However, we do know that the 4-quinolones display many properties which are not shared with any other group of antibacterial agents. This book raises the unanswered questions and assesses the potential significance to future chemotherapy of their unique features. The book also raises matters which are significant for physicians as well as for the pharmaceutical industry and the assessment of these agents by legislative bodies concerned with drug safety.
Download or read book DNA Damage and Repair written by A. Castellani and published by Springer Science & Business Media. This book was released on 2013-03-09 with total page 377 pages. Available in PDF, EPUB and Kindle. Book excerpt: The First International Congress on DNA Damage and Repair was held in Rome, Italy, July 12-17, 1987. It was organized by the Italian Com mission for Nuclear Alternative Energy Sources. The subject of DNA damage and repair involves almost all the fields ofbidogical sciences. Some of the more prominent ones include carcino genesis, photobiology, radiation biology, aging, enzymology, genetics, and molecular biology. These individual fields have their own interna tional meetings and although the meetings often have sessions devoted to DNA repair, they do not bring together a wide diversity of international workers in the field to exchange ideas. The purpose of the Congress was to facilitate such an exchange among scientists representing many fields of endeavor and many countries. The 37 manuscripts in this volume, presented by the invited spea kers during the four and half days of the Congress, encompass the field of DNA damage and repair. They cover biological systems ranging from mo lecules to humans and deal with damages and repair after treatment of cells with various types of radiations, chemicals, and exogenous and en dogenous oxidative damages. The Congress and its Proceedings are dedicated to two international leaders in the field of DNA damage and repair, Alexander Hollaender of the United States and Adriano Buzzati Traverso of Italy. Hollaender, who died in December 1986, was one of the first investigators to recognize the damage to DNA was important in cell killing and mutagenesis. His early work indicated that cells could recover from radiation injury.
Download or read book Molecular Biology of DNA Topoisomerases and Its Application to Chemotherapy written by Toshiwo Andoh and published by CRC Press. This book was released on 1992-10-26 with total page 400 pages. Available in PDF, EPUB and Kindle. Book excerpt: Molecular Biology of DNA Topoisomerases and Its Application to Chemotherapy is based on conference proceedings from the International Symposium on DNA Topoisomerases in Chemotherapy, held in Nagoya, Japan, in November 1991. The book opens with a discussion of the structural and functional properties of various types of DNA topoisomerases identified in prokaryotes and eukaryotes, in addition to their roles as cellular targets of anticancer and antimicrobial agents. Other topics addressed include the genetics and biology of DNA topoisomerases, inhibitors of microbial DNA topoisomerases and drug resistance, inhibitors of mammalian DNA topoisomerases and drug resistance, and preclinical and clinical studies of DNA topoisomerase inhibitors. Molecular Biology of DNA Topoisomerases and Its Application to Chemotherapy will broaden the understanding of biology and genetics of DNA topoisomerases and contribute to the development of antimicrobial and anticancer agents-inhibitors of topoisomerases. It will be invaluable for oncologists, molecular biologists, cellular biologists, geneticists, biochemists, and pharmaceutical researchers.
