Download or read book Fetal Research and Applications written by Institute of Medicine and published by National Academies Press. This book was released on 1994-02-01 with total page 116 pages. Available in PDF, EPUB and Kindle. Book excerpt: Research involving human fetuses and fetal tissue has been a subject of national debate and rancor for more than two decades. Despite the many demonstrated medical benefits of such research and the issuance of guidelines by various governmental and private ethics advisory bodies, federal support of this research has been severely curtailed. In 1993 the Institute of Medicine (IOM) sponsored a conference on fetal research and applications. This book examines the current state of fetal research and fetal tissue research. It contains an overview of research in the field and a short history on the regulatory and legislative actions governing the field. The bulk of the volume centers on ethical and legal issues of fetal research, preembryo research, fetal research, and fetal tissue transplantation. The volume also contains a full reprinting of the summary from the 1989 IOM book Medically Assisted Conception: An Agenda for Research, including the recommendations and research agenda suggested in that volume. Readers can therefore view that information in context with the suggestions and topics discussed at the conference. The background and research summarized in Fetal Research and Applications should provide insights for future progress and contribute to a fuller understanding of the social and ethical issues involved in this field.
Download or read book Fetal Research and Applications written by Institute of Medicine and published by National Academies Press. This book was released on 1994-02-01 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Research involving human fetuses and fetal tissue has been a subject of national debate and rancor for more than two decades. Despite the many demonstrated medical benefits of such research and the issuance of guidelines by various governmental and private ethics advisory bodies, federal support of this research has been severely curtailed. In 1993 the Institute of Medicine (IOM) sponsored a conference on fetal research and applications. This book examines the current state of fetal research and fetal tissue research. It contains an overview of research in the field and a short history on the regulatory and legislative actions governing the field. The bulk of the volume centers on ethical and legal issues of fetal research, preembryo research, fetal research, and fetal tissue transplantation. The volume also contains a full reprinting of the summary from the 1989 IOM book Medically Assisted Conception: An Agenda for Research, including the recommendations and research agenda suggested in that volume. Readers can therefore view that information in context with the suggestions and topics discussed at the conference. The background and research summarized in Fetal Research and Applications should provide insights for future progress and contribute to a fuller understanding of the social and ethical issues involved in this field.
Download or read book Background and Current Practice of Fetal Tissue and Embryo Research in Canada written by Canada. Royal Commission on New Reproductive Technologies and published by Canadian Government Publishing. This book was released on 1993 with total page 316 pages. Available in PDF, EPUB and Kindle. Book excerpt: These research studies cover human embryo and fetal tissue research, providing a concise overview of the subject; legal issues in embryo and fetal tissue research and therapy; origins, state of the art, future applications, and implications of human fetal tissue research; a survey of use and handling of human reproductive tissues in Canadian health care facilities; a survey of medical laboratories and medical waste disposal firms related to use and handling of human reproductive tissues; embryo transfer and related technologies in domestic animals; and the past, present, and future of human embryo research.
Download or read book Human Fetal Tissue Transplantation written by Niranjan Bhattacharya and published by Springer Science & Business Media. This book was released on 2013-02-26 with total page 467 pages. Available in PDF, EPUB and Kindle. Book excerpt: Many diseases earlier considered to be incurable are now being treated with modern innovations involving fetal tissue transplants and stem cells derived from fetal tissues. Fetal tissues are the richest source of fetal stem cells as well as other varying states of differentiated cells and support or stromal cells. The activity of such stem cells is at their peak provided they are given the correct niche. Stem cells, as we know, are immortal cells with the capacity to regenerate into any kind of differentiated cell as per niche-guidance. As such, fetal tissues have the potential capacity to mend, regenerate and repair damaged cells or tissues in adults, when directly transplanted to the site of injury, or even when transplanted in some other site, because it may have a homing capacity to migrate to the site of the specific injured organ. This is a new area of translational research and needs to be highlighted because of its immense potential. This book will bring together the new work of prominent medical scientists and clinicians who are conducting pioneering research in human fetal tissue transplantation. This will include direct transplant of healthy fetal tissue into mature patients as well as in hosts with genetic diseases. Transplant techniques, donor-host interaction, cell and tissue storage, ethical and legal issues, are some of the many matters which the book will deal with.
Download or read book The Use of Human Embryos and Fetal Tissues written by Michelle A. Mullen and published by . This book was released on 1992 with total page 41 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Stem Cells and the Future of Regenerative Medicine written by Institute of Medicine and published by National Academies Press. This book was released on 2002-01-25 with total page 112 pages. Available in PDF, EPUB and Kindle. Book excerpt: Recent scientific breakthroughs, celebrity patient advocates, and conflicting religious beliefs have come together to bring the state of stem cell researchâ€"specifically embryonic stem cell researchâ€"into the political crosshairs. President Bush's watershed policy statement allows federal funding for embryonic stem cell research but only on a limited number of stem cell lines. Millions of Americans could be affected by the continuing political debate among policymakers and the public. Stem Cells and the Future of Regenerative Medicine provides a deeper exploration of the biological, ethical, and funding questions prompted by the therapeutic potential of undifferentiated human cells. In terms accessible to lay readers, the book summarizes what we know about adult and embryonic stem cells and discusses how to go about the transition from mouse studies to research that has therapeutic implications for people. Perhaps most important, Stem Cells and the Future of Regenerative Medicine also provides an overview of the moral and ethical problems that arise from the use of embryonic stem cells. This timely book compares the impact of public and private research funding and discusses approaches to appropriate research oversight. Based on the insights of leading scientists, ethicists, and other authorities, the book offers authoritative recommendations regarding the use of existing stem cell lines versus new lines in research, the important role of the federal government in this field of research, and other fundamental issues.
Download or read book Research on the Fetus written by United States. National Commission for the Protection of Human Subjects of Biomedical and Behavioral Research and published by . This book was released on 1975 with total page 104 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Electronic Fetal Monitoring written by Cydney Afriat Menihan and published by Lippincott Williams & Wilkins. This book was released on 2007-05-29 with total page 326 pages. Available in PDF, EPUB and Kindle. Book excerpt: This comprehensive text emphasizes the practical application of electronic fetal monitoring (EFM). Case scenarios link various clinical situations with data interpretation to promote critical thinking. Relevant, up-to-date research helps readers develop problem solving skills; identify optimal treatment responses; and become familiar with the disease and nondisease conditions in pregnant patients that affect fetal health. More than 170 EFM strips complement the text. This edition has more monitoring strips and a new chapter on electronic record-keeping by a well-known expert. Electronic Fetal Monitoring: Concepts and Applications, Second Edition is a must-have purchase for anyone responsible for EFM interpretation.
Download or read book Human Fetal Tissue Transplantation Research written by Advisory Committee to the Director, National Institutes of Health and published by . This book was released on 1988 with total page 76 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book The Vaccine Race written by Meredith Wadman and published by Penguin. This book was released on 2018-09-04 with total page 466 pages. Available in PDF, EPUB and Kindle. Book excerpt: "A real jewel of science history...brims with suspense and now-forgotten catastrophe and intrigue...Wadman’s smooth prose calmly spins a surpassingly complicated story into a real tour de force."—The New York Times “Riveting . . . [The Vaccine Race] invites comparison with Rebecca Skloot's 2007 The Immortal Life of Henrietta Lacks.”—Nature The epic and controversial story of a major breakthrough in cell biology that led to the conquest of rubella and other devastating diseases. Until the late 1960s, tens of thousands of American children suffered crippling birth defects if their mothers had been exposed to rubella, popularly known as German measles, while pregnant; there was no vaccine and little understanding of how the disease devastated fetuses. In June 1962, a young biologist in Philadelphia, using tissue extracted from an aborted fetus from Sweden, produced safe, clean cells that allowed the creation of vaccines against rubella and other common childhood diseases. Two years later, in the midst of a devastating German measles epidemic, his colleague developed the vaccine that would one day wipe out homegrown rubella. The rubella vaccine and others made with those fetal cells have protected more than 150 million people in the United States, the vast majority of them preschoolers. The new cells and the method of making them also led to vaccines that have protected billions of people around the world from polio, rabies, chicken pox, measles, hepatitis A, shingles and adenovirus. Meredith Wadman’s masterful account recovers not only the science of this urgent race, but also the political roadblocks that nearly stopped the scientists. She describes the terrible dilemmas of pregnant women exposed to German measles and recounts testing on infants, prisoners, orphans, and the intellectually disabled, which was common in the era. These events take place at the dawn of the battle over using human fetal tissue in research, during the arrival of big commerce in campus labs, and as huge changes take place in the laws and practices governing who “owns” research cells and the profits made from biological inventions. It is also the story of yet one more unrecognized woman whose cells have been used to save countless lives. With another frightening virus--measles--on the rise today, no medical story could have more human drama, impact, or urgency than The Vaccine Race.
Download or read book Perinatal Tissue Derived Stem Cells written by Babak Arjmand and published by Springer. This book was released on 2016-12-01 with total page 246 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book covers several aspects of perinatal tissue-derived stem cells, from theoretical concepts to clinical applications. Topics include functions and different sources, immunomodulatory properties, translational point of view, GMP facility design and manufacturing for clinical translation, therapeutic potentials, and finally ethical considerations. The text provides a brief review of each type of perinatal stem cells and then focuses on their multi- or pluripotent properties, regenerative capacity, and future therapeutic potential in regenerative medicine. Additionally, the book discusses GMP compliance in stem cell facilities and the manufacture of stem cells for clinical translation. The chapters are authored by world-renowned experts in the perinatal stem cell field. Perinatal Tissue-Derived Stem Cells: Alternative Sources of Fetal Stem Cells, part of Springer’s Stem Cell Biology and Regenerative Medicine series, is essential reading for basic and clinical scientists, clinicians, and pharmaceutical experts working or conducting research in the fields of stem cell biology, molecular aspects of stem cell research, tissue engineering, regenerative medicine, and cellular therapy.
Download or read book Ethical Issues in Human Stem Cell Research Report and recommendations written by United States. National Bioethics Advisory Commission and published by . This book was released on 1999 with total page 128 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Current Research in Embryology written by Sabine Globig and published by CRC Press. This book was released on 2011-04-15 with total page 325 pages. Available in PDF, EPUB and Kindle. Book excerpt: Embryology—the study of embryos—is the branch of biological science that examines the formation and early development of an individual organism from fertilization of the egg (ovum) to birth. This collection of articles by embryology experts discusses research on some of the most important topics in embryology today. Topics include the cryopreservation of human embryos, in vitro generation of neurons from embryonic stem cells, embryonic transfer, transcriptional profiling, and more.
Download or read book Heritable Human Genome Editing written by The Royal Society and published by National Academies Press. This book was released on 2021-01-16 with total page 239 pages. Available in PDF, EPUB and Kindle. Book excerpt: Heritable human genome editing - making changes to the genetic material of eggs, sperm, or any cells that lead to their development, including the cells of early embryos, and establishing a pregnancy - raises not only scientific and medical considerations but also a host of ethical, moral, and societal issues. Human embryos whose genomes have been edited should not be used to create a pregnancy until it is established that precise genomic changes can be made reliably and without introducing undesired changes - criteria that have not yet been met, says Heritable Human Genome Editing. From an international commission of the U.S. National Academy of Medicine, U.S. National Academy of Sciences, and the U.K.'s Royal Society, the report considers potential benefits, harms, and uncertainties associated with genome editing technologies and defines a translational pathway from rigorous preclinical research to initial clinical uses, should a country decide to permit such uses. The report specifies stringent preclinical and clinical requirements for establishing safety and efficacy, and for undertaking long-term monitoring of outcomes. Extensive national and international dialogue is needed before any country decides whether to permit clinical use of this technology, according to the report, which identifies essential elements of national and international scientific governance and oversight.
Download or read book The Maternal Imprint written by Sarah S. Richardson and published by University of Chicago Press. This book was released on 2021-11-05 with total page 319 pages. Available in PDF, EPUB and Kindle. Book excerpt: Introduction: The Maternal Imprint -- Sex Equality in Heredity -- Prenatal Culture -- Germ Plasm Hygiene -- Maternal Effects -- Race, Birth Weight, and the Biosocial Body -- Fetal Programming -- It's the Mother! -- Epilogue: Gender and Heredity in the Postgenomic Moment.
Download or read book Guidelines for Human Embryonic Stem Cell Research written by National Research Council and published by National Academies Press. This book was released on 2005-09-15 with total page 224 pages. Available in PDF, EPUB and Kindle. Book excerpt: Since 1998, the volume of research being conducted using human embryonic stem (hES) cells has expanded primarily using private funds because of restrictions on the use of federal funds for such research. Given limited federal involvement, privately funded hES cell research has thus far been carried out under a patchwork of existing regulations, many of which were not designed with this research specifically in mind. In addition, hES cell research touches on many ethical, legal, scientific, and policy issues that are of concern to the public. This report provides guidelines for the conduct of hES cell research to address both ethical and scientific concerns. The guidelines are intended to enhance the integrity of privately funded hES cell research by encouraging responsible practices in the conduct of that research.
Download or read book Examining the State of the Science of Mammalian Embryo Model Systems written by National Academies of Sciences, Engineering, and Medicine and published by National Academies Press. This book was released on 2020-08-31 with total page 155 pages. Available in PDF, EPUB and Kindle. Book excerpt: Because of the recent advances in embryo modeling techniques, and at the request of the Office of Science Policy in the Office of the Director at the National Institutes of Health, the National Academies of Sciences, Engineering, hosted a 1-day public workshop that would explore the state of the science of mammalian embryo model systems. The workshop, which took place on January 17, 2020, featured a combination of presentations, panels, and general discussions, during which panelists and participants offered a broad range of perspectives. Participants considered whether embryo model systems - especially those that use nonhuman primate cells - can be used to predict the function of systems made with human cells. Presentations provided an overview of the current state of the science of in vitro development of human trophoblast. This publication summarizes the presentation and discussion of the workshop.
