Download or read book Innovation in Pharmacy Advances and Perspectives September 2018 written by Organizer Committee IPAP18 – Salamanca and published by Ediciones Universidad de Salamanca. This book was released on 2018-09-21 with total page 358 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book contains the summaries of the "Innovation in Pharmacy: Advances and Perspectives" that took place in Salamanca (Spain) in September 2018. The early science of chemistry and microbiology were the source of most drugs until the revolution of genetic engineering in the mid 1970s. Then biotechnology made available novel protein agents such as interferons, blood factors and monoclonal antibodies that have changed the modern pharmacy. Over the past year, a new pharmacy of oligonucleotides has emerged from the science of gene expression such as RNA splicing and RNA interference. The ability to design therapeutic agents from genomic sequences will transform treatment for many diseases. The science that created this advance and its future promise will be discussed. Phillip Allen Sharp is an American geneticist and molecular biologist who co-discovered RNA splicing. He shared the 1993 Nobel Prize in Physiology or Medicine with Richard J. Roberts for “the discovery that genes in eukaryotes are not contiguous strings but contain introns, and that the splicing of messenger RNA to delete those introns can occur in different ways, yielding different proteins from the same DNA sequence. He works in Institute Professor Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology (MIT), Cambridge, MA, US. Este libro recoge los resúmenes de la «Innovation in Pharmacy: Advances and Perspectives» que tuvo lugar en Salamanca (España) en septiembre de 2018. La ciencia primitiva de la química y la microbiología fue la fuente de la mayoría de las drogas hasta la revolución de la ingeniería genética a mediados de la década de 1970. Luego, la biotecnología puso a disposición agentes proteínicos novedosos como interferones, factores sanguíneos y anticuerpos monoclonales que han cambiado la farmacia moderna. Durante el año pasado, surgió una nueva farmacia de oligonucleótidos a partir de la ciencia de la expresión génica, como el empalme de ARN y la interferencia de ARN. La capacidad de diseñar agentes terapéuticos a partir de secuencias genómicas transformará el tratamiento de muchas enfermedades. La ciencia que creó este avance y su promesa futura será discutida. Phillip Allen Sharp es un genetista y biólogo molecular estadounidense que co-descubrió el empalme de ARN. Compartió el Premio Nobel de 1993 en Fisiología o Medicina con Richard J. Roberts por "el descubrimiento de que los genes en eucariotas no son cadenas contiguas, sino que contienen intrones, y que el empalme del ARN mensajero para eliminar esos intrones puede ocurrir de diferentes maneras, produciendo diferentes proteínas de la misma secuencia de ADN. Trabaja en el Instituto Profesor Koch Institute for Integrative Cancer Research, Instituto Tecnológico de Massachusetts (MIT), Cambridge, MA, EE. UU.

Download or read book Host Bibliographic Record for Boundwith Item Barcode 30112044669122 and Others written by and published by . This book was released on 2013 with total page 2562 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book The Mathematics of the Uncertain written by Eduardo Gil and published by Springer. This book was released on 2018-02-28 with total page 897 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book is a tribute to Professor Pedro Gil, who created the Department of Statistics, OR and TM at the University of Oviedo, and a former President of the Spanish Society of Statistics and OR (SEIO). In more than eighty original contributions, it illustrates the extent to which Mathematics can help manage uncertainty, a factor that is inherent to real life. Today it goes without saying that, in order to model experiments and systems and to analyze related outcomes and data, it is necessary to consider formal ideas and develop scientific approaches and techniques for dealing with uncertainty. Mathematics is crucial in this endeavor, as this book demonstrates. As Professor Pedro Gil highlighted twenty years ago, there are several well-known mathematical branches for this purpose, including Mathematics of chance (Probability and Statistics), Mathematics of communication (Information Theory), and Mathematics of imprecision (Fuzzy Sets Theory and others). These branches often intertwine, since different sources of uncertainty can coexist, and they are not exhaustive. While most of the papers presented here address the three aforementioned fields, some hail from other Mathematical disciplines such as Operations Research; others, in turn, put the spotlight on real-world studies and applications. The intended audience of this book is mainly statisticians, mathematicians and computer scientists, but practitioners in these areas will certainly also find the book a very interesting read.

Download or read book Educating Everybody s Children written by Robert W. Cole W. Cole and published by ASCD. This book was released on 2008-06-15 with total page 317 pages. Available in PDF, EPUB and Kindle. Book excerpt: Designed to promote reflection, discussion, and action among the entire learning community, Educating Everybody's Children encapsulates what research has revealed about successfully addressing the needs of students from economically, ethnically, culturally, and linguistically diverse groups and identifies a wide range of effective principles and instructional strategies. Although good teaching works well with all students, educators must develop an extensive repertoire of instructional tools to meet the varying needs of students from diverse backgrounds. Those tools and the knowledge base behind them are the foundation of this expanded and revised second edition of Educating Everybody's Children. Each strategy discussed in the book includes classroom examples and a list of the research studies that support it. The most important thing we have learned as a result of the education reform movement is that student achievement stands or falls on the motivation and skills of teachers. We must ensure that all teachers are capable of delivering a standards‐based curriculum that describes what students should know and be able to do, and that these standards are delivered by means of a rich and engaging "pedagogy of plenty." By these two acts we can ensure that all schools will be ready and able to educate everybody's children.

Download or read book Recollections of My Life written by Santiago Ramón y Cajal and published by . This book was released on 1966 with total page 702 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Innovating with Concept Mapping written by Alberto Cañas and published by Springer. This book was released on 2016-08-20 with total page 342 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book constitutes the refereed proceedings of the 7th International Conference on Concept Mapping, CMC 2016, held in Tallinn, Estonia, in September 2016. The 25 revised full papers presented were carefully reviewed and selected from 135 submissions. The papers address issues such as facilitation of learning; eliciting, capturing, archiving, and using “expert” knowledge; planning instruction; assessment of “deep” understandings; research planning; collaborative knowledge modeling; creation of “knowledge portfolios”; curriculum design; eLearning, and administrative and strategic planning and monitoring.

Download or read book bookdown written by Yihui Xie and published by CRC Press. This book was released on 2016-12-12 with total page 140 pages. Available in PDF, EPUB and Kindle. Book excerpt: bookdown: Authoring Books and Technical Documents with R Markdown presents a much easier way to write books and technical publications than traditional tools such as LaTeX and Word. The bookdown package inherits the simplicity of syntax and flexibility for data analysis from R Markdown, and extends R Markdown for technical writing, so that you can make better use of document elements such as figures, tables, equations, theorems, citations, and references. Similar to LaTeX, you can number and cross-reference these elements with bookdown. Your document can even include live examples so readers can interact with them while reading the book. The book can be rendered to multiple output formats, including LaTeX/PDF, HTML, EPUB, and Word, thus making it easy to put your documents online. The style and theme of these output formats can be customized. We used books and R primarily for examples in this book, but bookdown is not only for books or R. Most features introduced in this book also apply to other types of publications: journal papers, reports, dissertations, course handouts, study notes, and even novels. You do not have to use R, either. Other choices of computing languages include Python, C, C++, SQL, Bash, Stan, JavaScript, and so on, although R is best supported. You can also leave out computing, for example, to write a fiction. This book itself is an example of publishing with bookdown and R Markdown, and its source is fully available on GitHub.

Download or read book French Sociology written by Johan Heilbron and published by Cornell University Press. This book was released on 2015-11-06 with total page 286 pages. Available in PDF, EPUB and Kindle. Book excerpt: French Sociology offers a uniquely comprehensive view of the oldest and still one of the most vibrant national traditions in sociology. Johan Heilbron covers the development of sociology in France from its beginnings in the early nineteenth century through the discipline’s expansion in the late twentieth century, tracing the careers of figures from Auguste Comte to Pierre Bourdieu. Presenting fresh interpretations of how renowned thinkers such as Émile Durkheim and his collaborators defined the contours and content of the discipline and contributed to intellectual renewals in a wide range of other human sciences, Heilbron’s sophisticated book is both an innovative sociological study and a major reference work in the history of the social sciences. Heilbron recounts the halting process by which sociology evolved from a new and improbable science into a legitimate academic discipline. Having entered the academic field at the end of the nineteenth century, sociology developed along two separate tracks: one in the Faculty of Letters, engendering an enduring dependence on philosophy and the humanities, the other in research institutes outside of the university, in which sociology evolved within and across more specialized research areas. Distinguishing different dynamics and various cycles of change, Heilbron portrays the ways in which individuals and groups maneuvered within this changing structure, seizing opportunities as they arose. French Sociology vividly depicts the promises and pitfalls of a discipline that up to this day remains one of the most interdisciplinary endeavors among the human sciences in France.

Download or read book The Visions of Quevedo written by Francisco de Quevedo and published by Good Press. This book was released on 2019-12-17 with total page 105 pages. Available in PDF, EPUB and Kindle. Book excerpt: A satirical masterpiece, "The Visions of Quevedo" offers a glimpse into Spanish literature through the lens of Francisco de Quevedo. With sharp wit and keen observations, Quevedo critiques society, human nature, and the world around him, making this work a significant contribution to classic literature. His perspective offers a fresh take on traditional themes.

Download or read book Relativistic Quantum Information written by Fabrizio Tamburini and published by . This book was released on 2020-10-12 with total page 140 pages. Available in PDF, EPUB and Kindle. Book excerpt: Relativistic quantum information is one of the most exciting fields of physics today. Not only does it open possibilities for new forms of computing but it also calls into question the peaceful coexistence between classical space-time and quantum physics with scenarios that reopen the relationships between locality and nonlocality in the foundational structure of physics. Curated by two international experts Ignazio Licata and Fabrizio Tamburini, this volume hosts a selection of particularly significant essays for the new territories, and is dedicated to the 60th anniversary of Prof. Ignazio Licata.

Download or read book A Guide to the Latin American Art Song Repertoire written by Stela M. Brandão and published by Indiana University Press. This book was released on 2010-04-29 with total page 369 pages. Available in PDF, EPUB and Kindle. Book excerpt: A reference guide to the vast array of art song literature and composers from Latin America, this book introduces the music of Latin America from a singer's perspective and provides a basis for research into the songs of this richly musical area of the world. The book is divided by country into 22 chapters, with each chapter containing an introductory essay on the music of the region, a catalog of art songs for that country, and a list of publishers. Some chapters include information on additional sources. Singers and teachers may use descriptive annotations (language, poet) or pedagogical annotations (range, tessitura) to determine which pieces are appropriate for their voices or programming needs, or those of their students. The guide will be a valuable resource for vocalists and researchers, however familiar they may be with this glorious repertoire.

Download or read book Social Knowledge in the Making written by Charles Camic and published by University of Chicago Press. This book was released on 2012-07-24 with total page 464 pages. Available in PDF, EPUB and Kindle. Book excerpt: Over the past quarter century, researchers have successfully explored the inner workings of the physical and biological sciences using a variety of social and historical lenses. Inspired by these advances, the contributors to Social Knowledge in the Making turn their attention to the social sciences, broadly construed. The result is the first comprehensive effort to study and understand the day-to-day activities involved in the creation of social-scientific and related forms of knowledge about the social world. The essays collected here tackle a range of previously unexplored questions about the practices involved in the production, assessment, and use of diverse forms of social knowledge. A stellar cast of multidisciplinary scholars addresses topics such as the changing practices of historical research, anthropological data collection, library usage, peer review, and institutional review boards. Turning to the world beyond the academy, other essays focus on global banks, survey research organizations, and national security and economic policy makers. Social Knowledge in the Making is a landmark volume for a new field of inquiry, and the bold new research agenda it proposes will be welcomed in the social science, the humanities, and a broad range of nonacademic settings.

Download or read book The Complete Posthumous Poetry written by César Vallejo and published by Univ of California Press. This book was released on 1980-09-29 with total page 378 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Translation judges for the National Book Awards--Richard Miller, Alastair Reid, Eliot Weinberger--cited Clayton Eshleman and Jose Rubia Barcia's translation of Cesar Vallejo's The Complete Posthumous Poetry as follows: "This, the first National Book Award to be given to a translation of modern poetry, is a recognition of Clayton Eshleman's seventeen-year apprenticeship to perhaps the most difficult poetry in the Spanish language. Eshleman and his present collaborator, Jose Rubia Barcia, have not only rendered these complex poems into brilliant and living English, but have also established a definitive Spanish test based on Vallejo's densely rewritten manuscripts. In recreating this modern master in English, they have also made a considerable addition to poetry in our language."

Download or read book Spain s First Democracy written by Stanley G. Payne and published by Univ of Wisconsin Press. This book was released on 1993 with total page 498 pages. Available in PDF, EPUB and Kindle. Book excerpt: Payne's study places Spain's Second Republic within the historical framework of Spanish liberalism, and the rapid modernisation of inter-war Europe. He aims to present a consistent and detailed interpretation, demonstrating striking parallels to the German Weimar Republic.

Download or read book Biology written by Teresa Audesirk and published by Pearson. This book was released on 2011 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Includes 45 case studies and essays under the topics: Earth watch; Health watch; A closer look at ...; Scientific inquiry; Links to everyday life.

Download or read book Kagan Cooperative Learning Structures written by Spencer Kagan and published by . This book was released on 2013 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Big Picture in a MiniBook! Kagan Cooperative Learning Structures have revolutionized the way tens of thousands of teachers teach. Students achieve remarkable academic gains and acquire a range of social skills. Discipline problems disappear. And teaching and learning are fun! To good to be true? No. The data is in! This MiniBook reveals the secret to success. With no change in your curriculum, and with no specials materials, you will transform your class and your career. It is easy! Read this MiniBook and join the instructional revolution.

Download or read book Galaxies written by Francoise Combes and published by John Wiley & Sons. This book was released on 2021-03-05 with total page 288 pages. Available in PDF, EPUB and Kindle. Book excerpt: Galaxies are vast ensembles of stars, gas and dust, embedded in dark matter halos. They are the basic building blocks of the Universe, gathered in groups, clusters and super-clusters. They exist in many forms, either as spheroids or disks. Classifications, such as the Hubble sequence (based on mass concentration and gas fraction) and the colormagnitude diagram (which separates a blue cloud from a red sequence) help to understand their formation and evolution. Galaxies spend a large part of their lives in the blue cloud, forming stars as spiral or dwarf galaxies. Then, via a mechanism that is still unclear, they stop forming stars and quietly end in the red sequence, as spheroids. This transformation may be due to galaxy interactions, or because of the feedback of active nuclei, through the energy released by their central super-massive black holes. These mechanisms could explain the history of cosmic star formation, the rate of which was far greater in the first half of the UniverseÂs life. Galaxies delves into all of these surrounding subjects in six chapters written by dedicated, specialist astronomers and researchers in the field, from their numerical simulations to their evolutions.