Download or read book Deep Eutectic Solvents written by Yizhak Marcus and published by Springer. This book was released on 2018-12-05 with total page 205 pages. Available in PDF, EPUB and Kindle. Book excerpt: This is one of the first books fully dedicated to the rapidly advancing and expanding research area of deep eutectic solvents. Written by the internationally recognized expert in solution chemistry, it supplies full information regarding preparation of these new eco-friendly solvents, their properties and applications. The current and potential applications of deep eutectic solvents as organic reaction media, catalytic system, in biomass processing, nanotechnology and metal finishing industry, as well as for extraction and separation are extensively discussed.This highly informative and carefully presented book will appeal to practicing chemists (organic chemists, polymer chemists, biochemists) as well as chemical engineers and environmental scientists.
Download or read book Artemisinin Based and Other Antimalarials written by Guoqiao Li and published by Academic Press. This book was released on 2017-11-28 with total page 738 pages. Available in PDF, EPUB and Kindle. Book excerpt: Artemisinin-Based and Other Antimalarials: Detailed Account of Studies by Chinese Scientists Who Discovered and Developed Them provides a historical and scientific background of the discovery and development of artemisinin, artemisinin derivatives, combination drugs and related chemicals. It is a historical document, a scientific treatise, and a fascinating description of innovative research on new drug development that is carried out under extremely difficult conditions. The book also includes detailed experiments, physical-chemical procedures, practical methodologies and clinical trials. It is a valuable reference for students and researchers in the fields of scientific history, medicine, pharmaceutical science, chemistry, pharmacology and toxicology. - Presents details of all stages of drug development, including in vitro experiment, animal exploratory studies, animal tests for toxicity, safety and efficacy followed by stages I, II, III and IV, safety and efficacy in human volunteers and patients with malaria - Provides many physical-chemical laboratory procedures, such as NMR, MS, HPLC and X-ray diffraction used in drug development - Includes practical methodology of clinical trials from many research centers and countries to demonstrate the importance of this discovery
Download or read book Green Extraction of Natural Products written by Farid Chemat and published by John Wiley & Sons. This book was released on 2016-03-11 with total page 384 pages. Available in PDF, EPUB and Kindle. Book excerpt: Extraction processes are essential steps in numerous industrial applications from perfume over pharmaceutical to fine chemical industry. Nowadays, there are three key aspects in industrial extraction processes: economy and quality, as well as environmental considerations. This book presents a complete picture of current knowledge on green extraction in terms of innovative processes, original methods, alternative solvents and safe products, and provides the necessary theoretical background as well as industrial application examples and environmental impacts. Each chapter is written by experts in the field and the strong focus on green chemistry throughout the book makes this book a unique reference source. This book is intended to be a first step towards a future cooperation in a new extraction of natural products, built to improve both fundamental and green parameters of the techniques and to increase the amount of extracts obtained from renewable resources with a minimum consumption of energy and solvents, and the maximum safety for operators and the environment.
Download or read book Applied Thin Layer Chromatography written by Elke Hahn-Deinstrop and published by John Wiley & Sons. This book was released on 2007-02-27 with total page 330 pages. Available in PDF, EPUB and Kindle. Book excerpt: Thin-layer chromatography (TLC) is a powerful, fast and inexpensive analytical method. It has proven its usefulness in pharmaceutical, food and environmental analysis. This new edition of the practical TLC guide features a completely revised chapter on documentation, now including the use of digital cameras. Selected new sorbents and instruments are also introduced. Why has the prior edition been successful? All steps of the analytical procedure are clearly explained, starting with the choice of a suitable TLC technique and ending with data evaluation and documentation. Special emphasis is put on the proper choice of materials for TLC. Properties and functions of various materials and the TLC equipment are described, covering e. g. precoated layers, solvents and developing chambers, including information on suppliers. Many practical hints for trouble shooting are given. All this is illustrated with numerous coloured figures. How to use TLC in compliance with GLP/GMP regulations is described in detail, including the required documentation. Therefore the reader can very easily compile his own standard operating procedures.
Download or read book Green Process Engineering written by Martine Poux and published by CRC Press. This book was released on 2015-06-02 with total page 470 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book has been edited by Martine Poux, Patrick Cognet and Christophe Gourdon from the Laboratoire de Genie Chimique/ENSIACET, Toulouse. It presents an ensemble of methods and new chemical engineering routes that can be integrated in industrial processing for safer, more flexible, economical, and ecological production processes in the context of
Download or read book Fighting Multidrug Resistance with Herbal Extracts Essential Oils and Their Components written by Mahendra Rai and published by Academic Press. This book was released on 2013-05-24 with total page 291 pages. Available in PDF, EPUB and Kindle. Book excerpt: Fighting Multidrug Resistance with Herbal Extracts, Essential Oils and their Components offers scientists a single source aimed at fighting specific multidrug-resistant (MDR) microorganisms such as bacteria, protozoans, viruses and fungi using natural products. This essential reference discusses herbal extracts and essential oils used or under investigation to treat MDR infections, as well as those containing antimicrobial activity that could be of potential interest in future studies against MDR microorganisms. The need to combat multidrug-resistant microorganisms is an urgent one and this book provides important coverage of mechanism of action, the advantages and disadvantages of using herbal extracts, essential oils and their components and more to aid researchers in effective antimicrobial drug discovery - Addresses the need to develop safe and effective approaches to coping with resistance to all classes of antimicrobial drugs - Provides readers with current evidence-based content aimed at using herbal extracts and essential oils in antimicrobial drug development - Includes chapters devoted to the activity of herbal products against herpes, AIDS, tuberculosis, drug-resistant cancer cells and more
Download or read book Tu Youyou And The Discovery Of Artemisinin 2015 Nobel Laureate In Physiology Or Medicine written by Yi Rao and published by World Scientific. This book was released on 2016-09-28 with total page 223 pages. Available in PDF, EPUB and Kindle. Book excerpt: Nobel laureate Tu Youyou won the 2015 prize for Medicine/Physiology for the discovery of artemisinin, a drug therapy for malaria that has saved millions across the globe.This book traces the path of discovery beginning with Chairman Mao's 1964 instruction to Chinese researchers to find a cure for malaria, a disease that plagued the military and civilians alike in endemic regions. It chronicles the years of painstaking research to find effective anti-malarial drugs, and how an entry in a collection of traditional Chinese medicine prescriptions gave Tu Youyou the clue which led her to successfully extract artemisinin from the plant, Artemisia annua.Gathering together information from a variety of sources including first-hand accounts, this book describes the contributions of the many organisations, scientists, doctors and countless others who played a part in the process of discovery and clinical testing. It also provides insights into the challenges of carrying out such an extensive research project with limited resources during the upheavals of the Cultural Revolution. An inspirational read for young scientists.Includes the translation of Professor Tu Youyou's 2015 Nobel Lecture.
Download or read book From Artemisia annua L to Artemisinins written by Youyou Tu and published by Academic Press. This book was released on 2017-07-08 with total page 470 pages. Available in PDF, EPUB and Kindle. Book excerpt: Approx.426 pagesApprox.426 pages
Download or read book Ultrasound in Food Processing written by Malcolm J. W. Povey and published by Springer Science & Business Media. This book was released on 1998 with total page 300 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book addresses the future development of ultrasound in food processing, covering both High Power (material altering) and Low Power (non-destructive testing) applications. Leading work is presented for a non-expert audience, so that people in industry and academia can make informed decisions about future research and the adoption of ultrasound techniques. It will be of particular interest to food manufacturing personnel responsible for process development, engineering and research. It will be invaluable for scientists and technologists involved in active ultrasound research and instrument manufacture.
Download or read book Saving Lives Buying Time written by Institute of Medicine and published by National Academies Press. This book was released on 2004-09-09 with total page 384 pages. Available in PDF, EPUB and Kindle. Book excerpt: For more than 50 years, low-cost antimalarial drugs silently saved millions of lives and cured billions of debilitating infections. Today, however, these drugs no longer work against the deadliest form of malaria that exists throughout the world. Malaria deaths in sub-Saharan Africaâ€"currently just over one million per yearâ€"are rising because of increased resistance to the old, inexpensive drugs. Although effective new drugs called "artemisinins" are available, they are unaffordable for the majority of the affected population, even at a cost of one dollar per course. Saving Lives, Buying Time: Economics of Malaria Drugs in an Age of Resistance examines the history of malaria treatments, provides an overview of the current drug crisis, and offers recommendations on maximizing access to and effectiveness of antimalarial drugs. The book finds that most people in endemic countries will not have access to currently effective combination treatments, which should include an artemisinin, without financing from the global community. Without funding for effective treatment, malaria mortality could double over the next 10 to 20 years and transmission will intensify.
Download or read book Tu Youyou s Journey In The Search For Artemisinin written by Wenhu Zhang and published by World Scientific. This book was released on 2018-02-28 with total page 131 pages. Available in PDF, EPUB and Kindle. Book excerpt: Tu Youyou's Journey in the Search for Artemisinin is an autobiographical science book chronicling in detail the great experiences of Tu Youyou from her childhood to winning the Nobel Prize in Physiology or Medicine.As Tu Youyou is the first female scientist from China to win the Nobel Prize in Physiology or Medicine, this win created a sudden wave of interest in medicine, resulting in numerous autobiographical books about Tu Youyou appearing on the market. Contrary to these mass market titles, this book is uniquely different as it is fully authorized by the Nobel laureate herself. Her once-confidential experimental data and Artemisinin research reports are now revealed in this book for all to learn and comprehend. In addition, one of the book authors, Dr Wang Manyuan, is the only PhD student supervised by Professor Tu.Pharmaceutical researchers can use the book's valuable contents to reference, quote and analyse while searching for their own scientific inspirations. It also successfully serves as a guide for budding scientists and future Nobel Prize winners as it provides the proper guidance and methods of scientific research.
Download or read book Antimalarial Natural Products written by A. Douglas Kinghorn and published by Springer Nature. This book was released on 2022-01-02 with total page 116 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume begins with a short history of malaria and follows with a summary of its biology. It then traces the fascinating history of the discovery of quinine for malaria treatment, and then describes quinine’s biosynthesis, its mechanism of action, and its clinical use, concluding with a discussion of synthetic antimalarial agents based on quinine’s structure. It also covers the discovery of artemisinin and its development as the source of the most effective current antimalarial drug, including summaries of its synthesis and biosynthesis, its mechanism of action, and its clinical use and resistance. A short discussion of other clinically used antimalarial natural products leads to a detailed treatment of additional natural products with significant antiplasmodial activity, classified by compound type. Although the search for new antimalarial natural products from Nature’s combinatorial library is challenging, it is very likely to yield new antimalarial drugs. This book thus ends by identifying ten natural products with development potential as clinical antimalarial agents.
Download or read book Countering the Problem of Falsified and Substandard Drugs written by Institute of Medicine and published by National Academies Press. This book was released on 2013-06-20 with total page 377 pages. Available in PDF, EPUB and Kindle. Book excerpt: The adulteration and fraudulent manufacture of medicines is an old problem, vastly aggravated by modern manufacturing and trade. In the last decade, impotent antimicrobial drugs have compromised the treatment of many deadly diseases in poor countries. More recently, negligent production at a Massachusetts compounding pharmacy sickened hundreds of Americans. While the national drugs regulatory authority (hereafter, the regulatory authority) is responsible for the safety of a country's drug supply, no single country can entirely guarantee this today. The once common use of the term counterfeit to describe any drug that is not what it claims to be is at the heart of the argument. In a narrow, legal sense a counterfeit drug is one that infringes on a registered trademark. The lay meaning is much broader, including any drug made with intentional deceit. Some generic drug companies and civil society groups object to calling bad medicines counterfeit, seeing it as the deliberate conflation of public health and intellectual property concerns. Countering the Problem of Falsified and Substandard Drugs accepts the narrow meaning of counterfeit, and, because the nuances of trademark infringement must be dealt with by courts, case by case, the report does not discuss the problem of counterfeit medicines.
Download or read book Traditional Medicinal Plants and Malaria written by Merlin Willcox and published by CRC Press. This book was released on 2004-06-28 with total page 464 pages. Available in PDF, EPUB and Kindle. Book excerpt: Malaria is an increasing worldwide threat, with more than three hundred million infections and one million deaths every year. The worlds poorest are the worst affected, and many treat themselves with traditional herbal medicines. These are often more available and affordable, and sometimes are perceived as more effective than conventional antimala
Download or read book Use of Gamma Radiation Techniques in Peaceful Applications written by Basim Almayahi and published by BoD – Books on Demand. This book was released on 2019-10-02 with total page 262 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book deals with gamma radiation in many fields, which encompasses diverse factors that affect human and animal life inside an environment. These fields include nuclear and medical physics, industrial processes, environmental sciences, radiation biology, radiation chemistry, radiotherapy, agriculture and forestry, sterilization, the food industry, and so on. The book covers an overview of gamma background radiations and measurements, radioactive decay, radioecological applications in environmental gamma dosimetry, gamma-ray interaction, monocolor gamma, influence of gamma radiation on dynamical mechanical properties, influence of low-dose gamma irradiation treatments on microbial decontamination, gamma-ray ionization enhancement in tissues, gas-filled surge arresters, modeling plastic deformation located in irradiated materials, radiotherapy, application of radiation and genetic engineering techniques, and gamma-ray measurements using unmanned aerial systems. This book is expected to benefit undergraduate and postgraduate students, researchers, teachers, practitioners, policy makers, and every individual who has a concern for a healthy life.
Download or read book WHO Monograph on Good Agricultural and Collection Practices GACP for Artemisia Annua L written by and published by . This book was released on 2006 with total page 49 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Drug Repurposing in Cancer Therapy written by Kenneth K.W. To and published by Academic Press. This book was released on 2020-07-29 with total page 460 pages. Available in PDF, EPUB and Kindle. Book excerpt: Drug Repurposing in Cancer Therapy: Approaches and Applications provides comprehensive and updated information from experts in basic science research and clinical practice on how existing drugs can be repurposed for cancer treatment. The book summarizes successful stories that may assist researchers in the field to better design their studies for new repurposing projects. Sections discuss specific topics such as in silico prediction and high throughput screening of repurposed drugs, drug repurposing for overcoming chemoresistance and eradicating cancer stem cells, and clinical investigation on combination of repurposed drug and anticancer therapy. Cancer researchers, oncologists, pharmacologists and several members of biomedical field who are interested in learning more about the use of existing drugs for different purposes in cancer therapy will find this to be a valuable resource. - Presents a systematic and up-to-date collection of the research underpinning the various drug repurposing approaches for a quick, but in-depth understanding on current trends in drug repurposing research - Brings better understanding of the drug repurposing process in a holistic way, combining both basic and clinical sciences - Encompasses a collection of successful stories of drug repurposing for cancer therapy in different cancer types
