Download or read book Experimental Hematology Today 1985 written by S.J. Baum and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 158 pages. Available in PDF, EPUB and Kindle. Book excerpt: Experimental Hematology Today-1985 is a memento to the superb 14th Annual Meeting of the International Society for Experimental Hematology, held in Jerusa lem, Israel in July 1985. It represents a selection of the best presentations at the meeting. The manuscripts were selected by the local scientific committee and care fully reviewed by the editors. The yearbook is divided into five parts and represents the most recent advances in the basic sciences and clinical applications. Part I, under the leadership of Dr. L.A. Rozenszajn, is entitled "Hematopoietic Regulators." Papers in this section discuss the most recent discoveries on the phys iological regulation of hematopoiesis. Part II, "Hematopoietic Microenvironment," introduced by Dr. J.S. Greenberger, deals with the involvement ofthe hematopoietic microenvironment in the control of hematopoiesis. Dr. M. Saito leads Part Ill, "Dif ferentiation of Normal and Leukemic Cells," while Part IV, "Leukemic Cells in Leukemogenesis," is introduced by Dr. A. Raghavacher. The important discussions on recent advances in "Bone Marrow Transplantation," Part V, are headed by Dr. M.M. Bortin. Recent findings in many disciplines in experimental and clinical hematology are presented in this yearbook. It should be of considerable value to experimental and clinical scientists. The Editors v Contents Part I. Hematopoietic Regulators L.A. Rozenszajn 1. Role of T-Lymphocyte Colony Enhancing Factor, TLCEF, in the Induction of CFU -TL L.A. Rozenszajn, 1. Goldman, H. Poran, M.M. Werber, D. Shoham, and 1. Radnay ...

Download or read book Experimental Hematology Today 1988 written by Siegmund J. Baum and published by Springer Science & Business Media. This book was released on 2013-06-29 with total page 185 pages. Available in PDF, EPUB and Kindle. Book excerpt: Experimental Hematology Today - 1988 presents the latest results of research reflecting the diverse interests of basic and clinical hematologists. The major areas explored are hematopoietic regulation by cytokines; hematopoietic cellular growth regulation, with emphasis on the interaction of stromal with hematopoietic stem and progenitor cells; granulopoietic regulators; gene transfers into hematopoietic progenitor cells; leukemogenesis; and bone marrow transplantation. All chapters report on research or clinical findings of the past year.

Download or read book Experimental Hematology Today 1989 written by Norbert C. Gorin and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 248 pages. Available in PDF, EPUB and Kindle. Book excerpt: Experimental Hematology Today - 1989 comprises selected papers presented at the 18th Annual Meeting of the International Society for Experimental Hematology, July 16-20, 1989, Paris, France. Four major areas of research are explored: present aspects of stem cell transplantation; control of hemopoiesis; hemopoiesis in malignancies; and gene transfer. The role of autologous bone marrow transplantation in acute leukemia and in Hodgkin lymphoma, properties of the murine interleukin-3 receptor, effects of Ubenimex on proliferation and differentiation of human bone marrow cells and leukemic cell lines, immune system stimulation for the therapy of advanced stage neuroblastoma, and retro-viral gene transfer of human adenosine deaminase into hematopoietic cells are some of the topics considered. ^ ***BUCHHÄNDLERTEXT-E*** Selected papers from the 18th Annual Meeting of the International Society for Experimental Hematology. The proceedings are published annually and report on the latest experimental and clinical research.

Download or read book Predictive Drug Testing on Human Tumor Cells written by V. Hofmann and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 334 pages. Available in PDF, EPUB and Kindle. Book excerpt: Predictive drug testing on human tumor cells in order to define the appropriate chemotherapy will remain imperative as long as the anticancer agents available are few in number and show only limited activity. The advantages of an effective test would lie in obviating the need for testing antineoplastic agents on large cohorts of patients for assessment of drug activity (phase II studies) and in allowing determination of optimal use of anticancer agents (phase III trials). Such an in vitro test could help to better define dose and schedule of drugs preclinically. The additive value of individual drugs could be determined on tumor cells in vitro in order to define the best combination chemotherapy in vivo. Test-directed therapy would avoid unnecessary drug-related morbidity in patients with refractory tumors. Chemotherapy treatment would be more than justified even with side effects if palliation or even prolonged survival could be anticipated as a result. The benefits of predictive drug testing on human tumor cells would extend beyond improvement of individual patient treatment if the testing helped to identify new active agents. This spectrum of benefits to the entire field of oncology pro vides tremendous motivation for the development of such testing. Although a number of chemosensitivity tests have been proposed since the advent of modern anticancer chemotherapy, interest has been renewed by the possibility of cloning human tumor cells on agar plates, with a view to testing drug activity on cells with high pro liferation capacity.

Download or read book Current Catalog written by National Library of Medicine (U.S.) and published by . This book was released on 1983 with total page 1442 pages. Available in PDF, EPUB and Kindle. Book excerpt: First multi-year cumulation covers six years: 1965-70.

Download or read book National Library of Medicine Current Catalog written by National Library of Medicine (U.S.) and published by . This book was released on with total page 988 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Issues and Reviews in Teratology written by Harold Kalter and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 309 pages. Available in PDF, EPUB and Kindle. Book excerpt: There is still no clear understanding of what causes the great majority of human congenital malformations. And since in most sorts of human disease and pathology that yet prevail prevention usually awaits understanding of cause, it is generally thought that the same is true of developmental aberrations. But is this true? For the relatively few congenital malformations whose causes are primarily environmental, it is plain that their discovery has enabled prevention, but not nec essarily immediately. It took a generation from the time of the discovery that maternal rubella was teratogenic to learn how to immunize against it. Much debate occurred before it was appreciated that thalidomide was a teratogen, and only its removal from the pharmacist's shelf and the end of the epidemic of limb defects attributed to the drug overcame the last doubts. For other proven environmental teratogens doubts and difficulties still con tinue. The claimed prevalence of fetal genital distortions due to female sex hor mones may have been exaggerated. Some potentially teratogenic therapeutic drugs, like anticoagulants, anticonvulsants, and anticancer chemicals, are still pre scribed despite this danger because of their benefits to pregnant women. For those congenital malformations whose basis is predominantly genetic or chromosomal it is different, however. Prevention has not been achieved by the discovery of such causes, as dramatic and revolutionary as some of them have been, except in the questionable sense of interference with reproduction by genetic coun seling or prenatal elimination. But this has not inhibited the romanticists.

Download or read book Stem Cells written by C. Potten and published by Elsevier. This book was released on 1996-10-09 with total page 497 pages. Available in PDF, EPUB and Kindle. Book excerpt: Stem cells are relatively undifferentiated cells which are the permanent lineage ancestor cells of tissues. Newly developed molecular biological techniques and probes have made possible dramatic advances in our ability to study the lineage development of stem cells. A major impetus to develop these techniques has been to identify specific stem cells for gene therapy purposes. The role that stem cells play in the development of cancer is also an important area. This book provides up-to-date reviews on a wide variety of stem cell systems by world experts. Chapters range from descriptions of the current knowledge of the biology of stem cells, to current molecular biological approaches and clinical implications. Oncologists and cell biologists will find this book of particular interest. It will also be usefule to radiobiologist, biotechnologists, and gene therapists. - Provides reviews of stem cell systems by world experts - Covers stem cell biology in plants, invertebrates, and mammals - Presents clinical implications of stem cell differentiation

Download or read book Medical and Health Care Books and Serials in Print written by and published by . This book was released on 1997 with total page 1680 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Macrophages and Natural Killer Cells written by Sigurd J. Normann and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 814 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book is the outcome of a meeting held in Davos, Switzerland, February 7-12, 1982 focused primarily on mononuclear phagocytes and on natural killer (NK) cells. This IX International RES Congress was attended by 489 scientists from 31 countries and there were 340 scientific presentations in oral or poster session. The essential purpose of the Congress was to bring together scientists representing various aspects of mononuclear phagocyte biology to review and examine cri~ically the effects and mechanisms of macrophage growth control as well as the participatio~ of these cells in the afferent and efferent limbs of the immune response. Additional topics included the production and distribution of mono nuclear phagocytes; the intrinsic and extrinsic regulation of these cells; and the origin, nature, function and regulation of NK cells. The ultimate goal of the Congress was to enhance communication between scientists in various countries and disciplines so that new research directives could be defined with which to explore basic aspects of macrophage and NK cell participation in the control of cancer and infection.

Download or read book Monoclonal Antibodies T Cell Products written by David H Katz and published by CRC Press. This book was released on 2019-06-04 with total page 187 pages. Available in PDF, EPUB and Kindle. Book excerpt: First Published in 1982, this book offers a full, comprehensive guide into the applications of Monoclonal Antibodies. Carefully compiled and filled with a vast repertoire of notes, diagrams, and references this book serves as a useful reference for Students of Medicine, and other practitioners in their respective fields.

Download or read book Experimental Hematology Today 1982 written by Siegmund J. Baum and published by S. Karger AG (Switzerland). This book was released on 1982 with total page 298 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Blood cells in nuclear medicine part I written by M.R. Hardeman and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 419 pages. Available in PDF, EPUB and Kindle. Book excerpt: Xi List of first authors xiii Acknowledgements xv INTRODUCTICN Approaches to radiolabelling blood d-c cells: past, present and future M.L. Thakur 3 CELL LABELLllJG TEDlNIQUES 2 Labelling techniques of granulocytes and platelets 17 with 111 In-oxinate M.R. Hardeman, E.G.J. Eitjes-van Overbeek, A.J.M. van Velzen, M.H. Rovekarnp 111rndium-labelling of human washed platelets; kinetics 3 29 and in vivo sequestration sites M. Eber, J.P. Cazenave, J.C. Grob, J. Abecassis, G.!o1ethlin 111Indium loss from platelets by in vitro and ex 4 44 vivo manipulation R.J. Hawker, C.E. Hall, H. C-oldman, C.N. McCollum PIATELEl'S: KrnETIC STUDIES 5 The maturation of megakaryocytes and their precursors 65 J.H. Paulus 6!o1egakaryocytic precursors 74 J. Breton-Gorius, W. Vainchenker 7!-1ethods of quantification of platelet production 86 in man. A critical analysis Y. Najean vi 8 Platelet production rate deteDmination with (75se)_ seleno-m:thionine R. Cardinaud, E. Dassin 96 9 Platelet kinetics: the state of the art A. duP Heyns 110 10 Platelet kinetics A.M. Peters 130 Evaluation of models to deteDmine platelet life 11 span and survival curve shape M.G. LOtter, C.P. Herbst, P.N. Badenhorst, A. duP Heyns, P. Wessels, P.C. Minnaar 139 12 Canparison of three m:thods evaluating platelet survival tim: in patients with prosthetic heart valve J. Schbath, D. Ville, B. Hathy, B. Sanchini, E. Benveniste, J. Belleville, M. Dechavanne, J.P. Boissel, J.

Download or read book Vitamin D Chemical Biochemical and Clinical Endocrinology of Calcium Metabolism written by A. W. Norman and published by Walter de Gruyter GmbH & Co KG. This book was released on 2020-10-26 with total page 1319 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Textbook of Malignant Haematology written by Laurent Degos and published by CRC Press. This book was released on 1999-01-01 with total page 972 pages. Available in PDF, EPUB and Kindle. Book excerpt: This textbook provides a concise overview of malignant haematology, including reviews of cell and molecular biology, and implications for new trends in treatment.

Download or read book Current Hematology and Oncology written by and published by . This book was released on 1986 with total page 430 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Stem Cell Biology and Gene Therapy written by Peter J. Quesenberry and published by John Wiley & Sons. This book was released on 1998-09-10 with total page 586 pages. Available in PDF, EPUB and Kindle. Book excerpt: STEM CELL BIOLOGY AND GENE THERAPY Edited by Peter J. Quesenberry, Gary S. Stein, Bernard Forget, and Sherman Weissman Advances in molecular genetics and recombinant DNA technology have ushered in a new era in medical therapeutic research. New insights into the molecular basis of human disease and the role played by biological regulatory mechanisms have precipitated tremendous drug development efforts backed by intensive research into human gene therapy worldwide. Stem Cell Biology and Gene Therapy is the first book to thoroughly cover major advances in the field and their applications to novel molecular therapies. This self-contained volume integrates biological and clinical components of stem cell biology, examines some of the most difficult aspects of gene therapy, and provides a systematic review of advanced gene modification techniques. Twenty essays by leading researchers address some of the most compelling topics in contemporary medical research, including: * Fundamental regulatory mechanisms that operate in stem cells * Stem cells from a therapeutic perspective, including preparations of stem cells and their therapeutic potential as vehicles for gene therapy * Delivery systems for therapeutic genes, including an overview of the most promising vectors * Clinical applications for gene therapy, covering a broad range of diseases such as hemophilia, cancers, neurological disease, and more Complete with illustrations and real-world examples of a variety of disorders, Stem Cell Biology and Gene Therapy is essential for researchers in gene therapy and members of the biotechnology industry who are developing human molecular therapies for commercial use. It is also an important reference for molecular biologists, cell biologists, immunologists, molecular geneticists, hematologists, cancer researchers, biochemists, and anyone working in internal medicine.