Download or read book Evolutionary and Functional Relationships of Colonization Factor Antigen I and Other Class 5 Adhesive Fimbriae of Enterotoxigenic Escherichia Coli written by and published by . This book was released on 2004 with total page 13 pages. Available in PDF, EPUB and Kindle. Book excerpt: Colonization factor antigen I (CFA/I) is the archetype of eight genetically related fimbriae of enterotoxigenic Escherichia coli (ETEC) designated class 5 fimbriae. Assembled by the alternate chaperone pathway, these organelles comprise a rigid stalk of polymerized major subunits and an apparently tip-localized minor adhesive subunit. We examined the evolutionary relationships of class 5-specific structural proteins and correlated these with functional properties. We sequenced the gene clusters encoding coli surface antigen 4 (CS4), CS14, CS17, CS19, and putative colonization factor antigen O71 (PCFO71) and analyzed the deduced proteins and the published homologs of CFA/I, CS1, and CS2. Multiple alignment and phylogenetic analysis of the proteins encoded by each operon define three subclasses, 5a (CFA/I, CS4, and CS14), 5b (CS1, CS17, CS19, and PCFO71), and 5c (CS2). These share distant evolutionary relatedness to fimbrial systems of three other genera. Subclass divisions generally correlate with distinguishing in vitro adherence phenotypes of strains bearing the ETEC fimbriae. Phylogenetic comparisons of the individual structural proteins demonstrated greater intrasubclass conservation among the minor subunits than the major subunits. To correlate this with functional attributes, we made antibodies against CFA/I and CS17 whole fimbriae and maltose-binding protein fusions with the amino-terminal half of the corresponding minor subunits. Anti-minor subunit Fab preparations showed hemagglutination inhibition (HAI) of ETEC expressing homologous and intrasubclass heterologous colonization factors while anti-fimbrial Fab fractions showed HAI activity limited to colonization factor-homologous ETEC. These results were corroborated with similar results from the Caco-2 cell adherence assay. Our findings suggest that the minor subunits of class 5 fimbriae may be superior to whole fimbriae in inducing antiadhesive immunity.
Download or read book Pathogenic Escherichia Coli in Latin America written by Alfredo G. Torres and published by Bentham Science Publishers. This book was released on 2010 with total page 274 pages. Available in PDF, EPUB and Kindle. Book excerpt: Pathogenic Escherichia coli are known to be a common cause of diarrheal disease - a common cause of frequently occurring bacterial infections in children and adults in developing countries. It poses a significant problem in Latin America. Pathogenic Escherichia coli in Latin America presents current information on understanding pathogenic E. coli in Latin America and outlines prospects for future research in this region. It features a unique, comprehensive analysis of the most common categories of E. coli associated with diarrheal illness in Latin America. The aim of this book is to help epide.
Download or read book Travelers Vaccines written by Jane N. Zuckerman and published by PMPH-USA. This book was released on 2010 with total page 586 pages. Available in PDF, EPUB and Kindle. Book excerpt: Rev. ed. of: Travelers' vaccines / Elaine C. Jong, Jane N. Zuckerman. 2004.
Download or read book Advances in Applied Microbiology written by and published by Academic Press. This book was released on 2015-01-20 with total page 231 pages. Available in PDF, EPUB and Kindle. Book excerpt: A compilation of up to date reviews of topics in biotechnology and medical field. - Contributions from leading authorities - Informs and updates on all the latest developments in the field
Download or read book Population Genetics of Bacteria written by Seth T. Walk and published by American Society for Microbiology Press. This book was released on 2011-04-20 with total page 392 pages. Available in PDF, EPUB and Kindle. Book excerpt: Revisit the work of a pioneering innovator… • Explores the field of bacterial population genetics by highlighting the work of Thomas S. Whittam, best known for his work with enterohemorrhagic E. coli. • Features a compilation of research projects and ideas stemming from Dr. Whittam’s work that presents a broad perspective on the historical development of bacterial population genetics.
Download or read book Mucosal Vaccines written by David W. Pascual and published by Academic Press. This book was released on 2019-10-19 with total page 941 pages. Available in PDF, EPUB and Kindle. Book excerpt: Mucosal Vaccines: Innovation for Preventing Infectious Diseases discusses basic knowledge and discovery in the area of mucosal immunology and its related scientific fields. This completely updated, revised and authoritative treatise covers all aspects of mucosal vaccines, including their development, mechanisms of action, molecular/cellular aspects and practical applications. The book is organized in a unique format with basic, clinical and practical aspects described and discussed. The accumulated knowledge and new discoveries on the development of mucosal vaccines are logically introduced and discussed in an easy-to-understand format. - Provides the latest views on mucosal vaccines - Applies basic and current principles in the field of mucosal immunology and related scientific fields (e.g., microbiology, infectious diseases, systems biology, medicine, dentistry, veterinary medicine and translational research) to the development of new vaccines - Links basic, clinical and practical aspects of mucosal vaccines to different infectious diseases - Presents user-friendly organization using attractive illustrations
Download or read book Intestinal Microbiota in Health and Disease written by Eduardo J. Schiffrin and published by CRC Press. This book was released on 2014-02-11 with total page 345 pages. Available in PDF, EPUB and Kindle. Book excerpt: Now considered an organ with defensive and metabolic capabilities, the intestinal microbiota plays a major role in the local host immune system development and education. It contributes to the generation of a homeostatic balance characterized by the capacity to react against pathogens while remaining hyperresponsive/tolerant against commensals. Thi
Download or read book Microbial Transmission written by Fernando Baquero and published by John Wiley & Sons. This book was released on 2019-08-19 with total page 507 pages. Available in PDF, EPUB and Kindle. Book excerpt: Microbial transmission, the processes by which microbes transit to new environments, is a significant and broad-reaching concept with applications throughout the biological sciences. This collection of reviews, edited by an international team of experts studying and working across a range of disciplines, explores transmission not just as an idea in disease but as a fundamental biological process that acts in all domains of nature and exerts its force on disparate size scales, from the micro to the macro, and across units of time as divergent as a single bacterial replication cycle and the entire course of evolution. In five sections, this overview Defines the concept of transmission and covers basic processes of transmission, including causality, control strategies, fitness costs, virulence, and selection Presents numerous combinations of transmission scenarios across the bacterial, animal, and human interface Examines transmission as the defining characteristic of infectious disease Presents methods for experimentally verifying and quantifying transmission episodes Concludes with important theoretical and modeling approaches Anyone studying or working in microbial colonization, evolution, pathogenicity, antimicrobial resistance, or public health will benefit from a deeper understanding of Microbial Transmission.
Download or read book Cumulated Index Medicus written by and published by . This book was released on 1996 with total page 1340 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Diseases of Poultry written by and published by John Wiley & Sons. This book was released on 2019-11-19 with total page 1488 pages. Available in PDF, EPUB and Kindle. Book excerpt: The most complete and definitive reference to all aspects of poultry diseases, Diseases of Poultry, Fourteenth Edition has been fully revised and updated to offer a comprehensive survey of current knowledge. Updates the definitive reference of poultry health and disease Provides more clinically relevant information on management of specific diseases, contributed by clinical poultry veterinarians Offers information on disease control in organic and antibiotic-free production Presents more concise, streamlined chapters for ease of use Incorporates advances in the field, from new diagnostic tools and information to changes brought about by the increasing globalization and the re-emergence of zoonotic pathogens
Download or read book Attachment Of Organisms To The Gut Mucosa written by Edgar C. Boedeker and published by CRC Press. This book was released on 2018-01-18 with total page 477 pages. Available in PDF, EPUB and Kindle. Book excerpt: The present volumes are based on the presentations made during the October 1981 research work shopThe attachment of micro-organisms to the intestinal mucosa which was held in Reston, Virginia. The workshop was supported by the American Gastroenterological Association, along with the National Institutes of Health.
Download or read book Structure and Function Relationships of the Binding of and galactosylated Oligosaccharides to K88 Fimbriae of Enterotoxigenic Escherichia Coli written by and published by . This book was released on 2018 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Bacterial Adhesion to Cells and Tissues written by Itzhak Ofek and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 585 pages. Available in PDF, EPUB and Kindle. Book excerpt: Attachment to host cells or tissues is often the first step in the establishment of bacterial infections. A complex array of recognition, attachment, and virulence factors is involved in this process, which recent research has greatly illuminated. This comprehensive and authoritative volume discusses the specific cell and tissue-specific affinities of pathogenic microorganisms, including bioinorganic surfaces such as teeth, and is an essential reference for researchers and students of host-pathogen interactions.
Download or read book Microbiology of Waterborne Diseases written by and published by Academic Press. This book was released on 2013-11-08 with total page 719 pages. Available in PDF, EPUB and Kindle. Book excerpt: The second edition of Microbiology of Waterborne Diseases describes the diseases associated with water, their causative agents and the ways in which they gain access to water systems. The book is divided into sections covering bacteria, protozoa, and viruses. Other sections detail methods for detecting and identifying waterborne microorganisms, and the ways in which they are removed from water, including chlorine, ozone, and ultraviolet disinfection. The second edition of this handbook has been updated with information on biofilms and antimicrobial resistance. The impact of global warming and climate change phenomena on waterborne illnesses are also discussed. This book serves as an indispensable reference for public health microbiologists, water utility scientists, research water pollution microbiologists environmental health officers, consultants in communicable disease control and microbial water pollution students. Focuses on the microorganisms of most significance to public health, including E. coli, cryptosporidium, and enterovirus Highlights the basic microbiology, clinical features, survival in the environment, and gives a risk assessment for each pathogen Contains new material on antimicrobial resistance and biofilms Covers drinking water and both marine and freshwater recreational bathing waters
Download or read book Studies on the Organization and Regulation of the Colonization Factor Antigen 1 CFA 1 Fimbrial System of Escherichia Coli written by Tuomo Kalle Karjalainen and published by . This book was released on 1990 with total page 340 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Colonization factors of enterotoxigenic Escherichia coli written by Harleen M. S. Grewal and published by . This book was released on 1994 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Bacterial Pathogenesis written by and published by Academic Press. This book was released on 1998-07-01 with total page 643 pages. Available in PDF, EPUB and Kindle. Book excerpt: Established almost 30 years ago, Methods in Microbiology is the most prestigious series devoted to techniques and methodology in the field. Now totally revamped, revitalized, with a new format and expanded scope, Methods in Microbiology will continue to provide you with tried and tested, cutting-edge protocols to directly benefit your research. - Focuses on the methods most useful for the microbiologist interested in the way in which bacteria cause disease - Includes section devoted to 'Approaches to characterising pathogenic mechanisms' by Stanley Falkow - Covers safety aspects, detection, identification and speciation - Includes techniques for the study of host interactions and reactions in animals and plants - Describes biochemical and molecular genetic approaches - Essential methods for gene expression and analysis - Covers strategies and problems for disease control
