Download or read book Eukaryotic Gene Expression written by Ajit Kumar and published by Springer Science & Business Media. This book was released on 2013-03-09 with total page 238 pages. Available in PDF, EPUB and Kindle. Book excerpt: The recent surge of interest in recombinant DNA research is understandable considering that biologists from all disciplines, using recently developed mo lecular techniques, can now study with great precision the structure and regulation of specific genes. As a discipline, molecular biology is no longer a mere subspeciality of biology or biochemistry: it is the new biology. Current approaches to the outstanding problems in virtually all the traditional disci plines in biology are now being explored using the recombinant DNA tech nology. In this atmosphere of rapid progress, the role of information exchange and swift publication becomes quite crucial. Consequently, there has been an equally rapid proliferation of symposia volumes and review articles, apart from the explosion in popular science magazines and news media, which are always ready to simplify and sensationalize the implications of recent dis coveries, often before the scientific community has had the opportunity to fully scrutinize the developments. Since many of the recent findings in this field have practical implications, quite often the symposia in molecular biology are sponsored by private industry and are of specialized interest and in any case quite expensive for students to participate in. Given that George Wash ington University is a teaching institution, our aim in sponsoring these Annual Spring Symposia is to provide, at cost, a forum for students and experts to discuss the latest developments in selected areas of great significance in biology. Additionally, since the University is located in Washington, D. C.
Download or read book Transfer and Expression of Eukaryotic Genes written by H.S. Ginsberg and published by Academic Press. This book was released on 2012-12-02 with total page 329 pages. Available in PDF, EPUB and Kindle. Book excerpt: Transfer and Expression of Eukaryotic Genes documents the progress in our understanding of the transfer and expression of eukaryotic genes. This book covers topics organized around three themes: gene expression and its regulation; in vivo gene transfer and development; and viral gene and oncogene systems. This text is divided into three sections encompassing 25 chapters and begins with an overview of the molecular basis of gene expression, with emphasis on transcription complexes that account for transcription control in eukaryotic genes. It then turns to experiments that assess the in vitro stimulatory effect of the SV40 72-bp repeat on specific transcription from heterologous promoter elements using a HeLa whole cell extract. The reader is methodically introduced to the regulation signals and factors of histone gene transcription; transcriptional control of beta-globin and liver-specific genes in mouse cells; and gene transfer in Drosophila and the sea urchin Strongylocentrotus purpuratus. This book also considers the splicing of messenger RNA precursors and the regulation of thymidine kinase enzyme expression, and then concludes with a chapter that describes the activation of the myc oncogene by chromosomal translocation. This book will be of interest to students and researchers in fields ranging from molecular genetics to microbiology, biochemistry, pathology, and immunology.
Download or read book Eukaryotic Genes written by Norman Maclean and published by Butterworth-Heinemann. This book was released on 1983 with total page 504 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Eucaryotic Gene Regulation written by Richard Axel and published by Elsevier. This book was released on 2012-12-02 with total page 682 pages. Available in PDF, EPUB and Kindle. Book excerpt: Eukaryotic Gene Regulation covers the aspects and mechanisms of gene regulation of selected eukaryotes, such as yeast, Drosophila, and insect. This book is organized into eight parts, encompassing 52 chapters. The majority of the chapters are presented in an experimental manner containing an abstract, methods, results and discussion, and conclusion. This book first gives a short overview of the evolutionary role of interspersion in eukaryotic genes. It then presents considerable chapters on control of gene expression in yeast; gene mutation and isolation; structure and function; and analysis. Part III focuses on genetic and DNA sequence analysis in Drosophila. It includes discussions on allelic complementation and transvection, genetic organization, histone gene, and gene transcription. Part IV examines cell lineage; gene expression and sequences; and protein synthesis of insects, sea urchin, and mammalian cells. This is followed by discussions on structure and expression of specific eukaryotic genes from chicken, rat, rabbit, and human. Topics on the transfer of genetic information within and between cells and the structure and function of chromosome are significantly considered in Parts VI and VII. Genes evaluated in these sections include heavy chain immunoglobulin, light chain, beta-globin, and dihydrofolate reductase. Furthermore, this book describes the in vitro transcription and the factors involved; internal organization and mechanism of assembly of nucleosome; and chromatin structure. The concluding section focuses on aspects of viral genome expression including gene regulation, synthesis, processing, and alternative RNA splicing. Research biologists, geneticists, scientists, teachers, and students will greatly benefit from this book.
Download or read book Architecture of Eukaryotic Genes written by Günter Kahl and published by . This book was released on 1988 with total page 540 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Eukaryotic Gene Regulation written by Gerald M. Kolodny and published by CRC Press. This book was released on 2018-01-18 with total page 277 pages. Available in PDF, EPUB and Kindle. Book excerpt: The cause of cancer and its many manifestations is at present unknown. Since many of its manifestations, including is control of cell division, appear to represent abnormal patterns of gene expression, studies of the regulation of gene expression nwill provide important insights in the understanding and treatment of cancer. This volume attempts to present some of the recent work on regulation of gene expression in eukaryotic cells.
Download or read book Gene Regulation written by David S. Latchman and published by Chapman & Hall. This book was released on 1995 with total page 296 pages. Available in PDF, EPUB and Kindle. Book excerpt: Gene Regulation provides a complete and concise picture of the processes regulating gene expression in higher organisms and man. The second edition of this well reviewed textbook has been extensively updated to reflect the scientific progress made in this area over the last four years.
Download or read book Changes in Eukaryotic Gene Expression in Response to Environmental Stress written by Burr Atkinson and published by Elsevier. This book was released on 2012-12-02 with total page 400 pages. Available in PDF, EPUB and Kindle. Book excerpt: Changes in Eukaryotic Gene Expression in Response to Environmental Stress focuses on various aspects of eukaryotic cell's response to heat stress (shock) and other stress stimuli. This book is organized into two major sections, encompassing 17 chapters that reflect the emphasis on research utilizing Drosophila, a variety of animal systems, and plants. This book first provides a brief introduction to the organization, sequences, and induction of heat shock proteins and related genes. It then describes the control of transcription during heat shock from the standpoint of molecular biology and evolutionary variations of the mechanisms in organisms with diverse metabolic needs. It goes on to discuss the issue of coordinate and noncoordinate responses of heat shock genes. It presents a model for post-transcriptional regulation on certain aspects of coordinate and noncoordinate regulations. Chapters 6-12 discuss heat shock proteins and genes and the effects of stress on gene expression of sea urchin, avian, and mammalian cells. The second part of the book focuses on the physiological role of heat shock proteins and genes in plants and fungi. It includes a discussion on experimental problems encountered during studies of the mechanisms of inhibition of photosynthesis by unfavorable environmental conditions. The changes in transcription and translation of specific mRNAs in the developing embryo during heat shock at various temperatures are described. The concluding chapters deal with heat shock response in plants, particularly the response in soybeans and maize, covering both physiological and molecular analyses. Research scientists, clinicians, and agriculturists will greatly benefit from the information presented in this book.
Download or read book The Nucleolus written by Mark O. J. Olson and published by Springer Science & Business Media. This book was released on 2011-09-15 with total page 434 pages. Available in PDF, EPUB and Kindle. Book excerpt: Within the past two decades, extraordinary new functions for the nucleolus have begun to appear, giving the field a new vitality and generating renewed excitement and interest. These new discoveries include both newly-discovered functions and aspects of its conventional role. The Nucleolus is divided into three parts: nucleolar structure and organization, the role of the nucleolus in ribosome biogenesis, and novel functions of the nucleolus.
Download or read book Principles of Biology written by Lisa Bartee and published by . This book was released on 2017 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt: The Principles of Biology sequence (BI 211, 212 and 213) introduces biology as a scientific discipline for students planning to major in biology and other science disciplines. Laboratories and classroom activities introduce techniques used to study biological processes and provide opportunities for students to develop their ability to conduct research.
Download or read book Untranslated Gene Regions and Other Non coding Elements written by Lucy W. Barrett and published by Springer Science & Business Media. This book was released on 2013-06-26 with total page 63 pages. Available in PDF, EPUB and Kindle. Book excerpt: There is now compelling evidence that the complexity of higher organisms correlates with the relative amount of non-coding RNA rather than the number of protein-coding genes. Previously dismissed as “junk DNA”, it is the non-coding regions of the genome that are responsible for regulation, facilitating complex temporal and spatial gene expression through the combinatorial effect of numerous mechanisms and interactions working together to fine-tune gene expression. The major regions involved in regulation of a particular gene are the 5’ and 3’ untranslated regions and introns. In addition, pervasive transcription of complex genomes produces a variety of non-coding transcripts that interact with these regions and contribute to regulation. This book discusses recent insights into the regulatory roles of the untranslated gene regions and non-coding RNAs in the control of complex gene expression, as well as the implications of this in terms of organism complexity and evolution.
Download or read book The Eukaryote Genome in Development and Evolution written by John Bernard and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 432 pages. Available in PDF, EPUB and Kindle. Book excerpt: 'The mind unlearns with difficulty what has long been impressed upon it. ' Seneca Reductionism, is, without question, the most successful analytical approach available to the experimental scientist. With the advent of techniques for cloning and sequencing DNA, and the development of a variety of molecular probes for localizing macromolecules in cells and tissues, the biologist now has available the most powerful reductionist tools ever invented. The application of these new technologies has led to a veritable explosion of facts regarding the types and organization of nucleotide sequences present in the genomes of eukaryotes. These data offer a level of precision and predictability which is unparalleled in biology. Recombinant DNA techniques were initially developed to gather information about the structure and organization of the DNA sequences within a genome. The power and potential of these techniques, however, extend far beyond simple data collection of this kind. In an attempt to use the new technology as a basis for analyzing development and evolution, attention was first focused on the topic of gene regulation, an approach that had proven so successful in prokaryotes. It is now clear that this has not been an adequate approach. Lewin (1984) has quoted Brenner as stating 'at the beginning it was said that the answer to the understanding of development was going to come from a knowledge of the molecular mechanisms of gene control. I doubt whether anyone believes this any more.
Download or read book Eukaryotic Transcription Factors written by David S. Latchman and published by Academic Press. This book was released on 2003-11-21 with total page 391 pages. Available in PDF, EPUB and Kindle. Book excerpt: Now in two-colour throughout, the fourth edition of Eukaryotic Transcription Factors has been completely rewritten and restructured to take into account the tremendous advances in our understanding of transcription factors and the mechanisms by which they act. Considerable emphasis has been given to the interaction between transcription factors and chromatin structure. Also included is an entirely new section on the mediator complex and expansion of the space devoted to co-activators and co-repressors.This book is essential reading for all those who wish to understand the impact of molecular biology on medicine, whatever their speciality. - Major families of eukaryotic transcription factors described - Mechanisms of gene activation and repression analysed - Structure-function relationships indicated - Interaction between transcription factors and chromatin structure described - Roles in inducible and cell type-specific gene expression - Roles in development, differentiation and human diseases including cancer - Methods of study in vitro and in vivo
Download or read book Concepts of Biology written by Samantha Fowler and published by . This book was released on 2023-05-12 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Black & white print. Concepts of Biology is designed for the typical introductory biology course for nonmajors, covering standard scope and sequence requirements. The text includes interesting applications and conveys the major themes of biology, with content that is meaningful and easy to understand. The book is designed to demonstrate biology concepts and to promote scientific literacy.
Download or read book Gene Regulation in Eukaryotes written by Edgar Wingender and published by Wiley-Blackwell. This book was released on 1993 with total page 452 pages. Available in PDF, EPUB and Kindle. Book excerpt: A much-needed guide through the overwhelming amount of literature in the field. Comprehensive and detailed, this book combines background information with the most recentinsights. It introduces current concepts, emphasizing the transcriptional control of genetic information. Moreover, it links data on the structure of regulatory proteins with basic cellular processes. Both advanced students and experts will find answers to such intriguing questions as: - How are programs of specific gene repertoires activated and controlled? - Which genes drive and control morphogenesis? - Which genes govern tissue-specific tasks? - How do hormones control gene expression in coordinating the activities of different tissues? An abundant number of clearly presented glossary terms facilitates understanding of the biological background. Speacial feature: over 2200 (!) literature references.
Download or read book Chance in Evolution written by Grant Ramsey and published by University of Chicago Press. This book was released on 2016-10-25 with total page 368 pages. Available in PDF, EPUB and Kindle. Book excerpt: This illuminating volume explores the effects of chance on evolution, covering diverse perspectives from scientists, philosophers, and historians. The evolution of species, from single-celled organisms to multicellular animals and plants, is the result of a long and highly chancy history. But how profoundly has chance shaped life on earth? And what, precisely, do we mean by chance? Bringing together biologists, philosophers of science, and historians of science, Chance in Evolution is the first book to untangle the far-reaching effects of chance, contingency, and randomness on the evolution of life. The book begins by placing chance in historical context, starting with the ancients and moving through Darwin to contemporary biology. It documents the shifts in our understanding of chance as Darwin’s theory of evolution developed into the modern synthesis, and how the acceptance of chance in Darwinian theory affected theological resistance to it. Other chapters discuss how chance relates to the concepts of genetic drift, mutation, and parallel evolution—as well as recent work in paleobiology and the experimental evolution of microbes. By engaging in collaboration across biology, history, philosophy, and theology, this book offers a comprehensive overview both of the history of chance in evolution and of our current understanding of the impact of chance on life.
Download or read book Mechanisms of Eukaryotic DNA Recombination written by Max E Gottesman and published by Academic Press. This book was released on 2014-06-28 with total page 228 pages. Available in PDF, EPUB and Kindle. Book excerpt: Mechanisms of Eukaryotic DNA Recombination is a collection of papers that discusses advances in eukaryotic genetic recombination. Papers address issues in eukaryotic genetic recombination, particularly DNA integration in mammalian genomes, genetic recombination in Drosophila or Caenorhabditis; the manipulation of the mouse genome; genome organization; and genetic recombination in protozoa. One paper discusses chromatid interactions during intrachromosomal recombination in mammalian cells, namely, intrachromatid and sister chromatid. Another paper analyzes the implication for chromosomal recombination and gene targeting; results on extrachromosomal recombination show that circles are inefficient substrates for recombination even if only one of two substrates in an intermolecular reaction is circular. One author discusses the genetics and molecular biology of recombination, citing the work of Watson and Crick, stating that crossing-over occurs between genes (not within them). He also explains that the formation and resolution of recombination intermediaries depend on enzyme or other proteins. This book will prove invaluable to cellular biologists, microbiologists, and researchers engaged in genetics and general biology.
