Download or read book Molecular Pathology written by William B. Coleman and published by Academic Press. This book was released on 2017-11-09 with total page 805 pages. Available in PDF, EPUB and Kindle. Book excerpt: As the molecular basis of human disease becomes better characterized, and the implications for understanding the molecular basis of disease becomes realized through improved diagnostics and treatment, Molecular Pathology, Second Edition stands out as the most comprehensive textbook where molecular mechanisms represent the focus. It is uniquely concerned with the molecular basis of major human diseases and disease processes, presented in the context of traditional pathology, with implications for translational molecular medicine. The Second Edition of Molecular Pathology has been thoroughly updated to reflect seven years of exponential changes in the fields of genetics, molecular, and cell biology which molecular pathology translates in the practice of molecular medicine. The textbook is intended to serve as a multi-use textbook that would be appropriate as a classroom teaching tool for biomedical graduate students, medical students, allied health students, and others (such as advanced undergraduates). Further, this textbook will be valuable for pathology residents and other postdoctoral fellows that desire to advance their understanding of molecular mechanisms of disease beyond what they learned in medical/graduate school. In addition, this textbook is useful as a reference book for practicing basic scientists and physician scientists that perform disease-related basic science and translational research, who require a ready information resource on the molecular basis of various human diseases and disease states. Explores the principles and practice of molecular pathology: molecular pathogenesis, molecular mechanisms of disease, and how the molecular pathogenesis of disease parallels the evolution of the disease Explains the practice of “molecular medicine and the translational aspects of molecular pathology Teaches from the perspective of “integrative systems biology Enhanced digital version included with purchase

Download or read book The Trypanosome Surface written by Étienne Pays and published by De Boeck Supérieur. This book was released on 1999 with total page 300 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book deals with the cellular surface of the parasite Trypanosoma brucei, which is responsible for human sleeping sickness and the nagana disease of cattle, two plagues of the African continent. In the mammalian bloodstream, the trypanosome evades the immune defenses of the host through a continuous variation of its major surface antigen, the VSG (Variant Surface Glycoprotein). The first part of the book is devoted to the study of the genetic mechanisms involved in this process of antigenic variation. The second part is focused on the genetic mechanisms underlying the changes of surface proteins which occur during the life-cycle of the parasite, alternating between the tsetse fly and the mammal. Finally, our knowledge about the surface receptors of trypanosomes, as well as their possible vaccination potential against trypanosomiases, is discussed.

Download or read book Cases in Critical Cross Cultural Management written by Jasmin Mahadevan and published by Routledge. This book was released on 2019-11-07 with total page 212 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book is a collection of 16 empirical cases in critical Cross-Cultural Management (CCM). All cases approach culture in CCM beyond national cultures, and all examine power as an integrative part of any cross-cultural situation. The cases also consider diversity in the sense of culturally or historically learned categorizations of difference (such as gender, race, ethnicity, religion and class), and acknowledge how diversity categories might differ across cultures. Furthermore, each case suggests a specific method or concept for improving upon the situation. Out of this approach, novel insights emerge: we can see how culture, power and diversity categories are inseparable, and we can understand how exactly this is the case. The uses and benefits of this book are thus both conceptual and methodological; they emerge at the intersections of Critical CCM and diversity studies. All cases also discuss implications for practitioners and are suitable for teaching. Mainstream CCM often limits itself to comparative models or cultural dimensions. This approach is widely critiqued for its simplicity but is equally used for the exact same reason. Often, academics teach this approach whilst cautioning students against implementing it, and this might be simply due to a lack of alternatives. Through means of rich empirical cases, this book offers such an alternative. Considering the intersections of culture, diversity and power enables students, researchers and practitioners alike to see ‘more’ or ‘different’ things in the situation, and then come up with novel approaches and solutions that do justice to the realities of culture and diversity in today’s (and the future's) management and organizations. The chapters of this book thus offer concepts and methods to approach cross-cultural situations: the conceptual gain lies in bringing together CCM and (critical) diversity studies in an easily accessible manner. As a methodological contribution, the cases in this book offer the concise tools and methods for implementing an intersectional approach to culture.

Download or read book Essential Concepts in Molecular Pathology written by William B. Coleman and published by Academic Press. This book was released on 2019-11-23 with total page 634 pages. Available in PDF, EPUB and Kindle. Book excerpt: Essential Concepts in Molecular Pathology, Second Edition, offers an introduction to molecular genetics and the "molecular" aspects of human disease. The book illustrates how pathologists harness their understanding of these entities to develop new diagnostics and treatments for various human diseases. This new edition offers pathology, genetics residents, and molecular pathology fellows an advanced understanding of the molecular mechanisms of disease that goes beyond what they learned in medical and graduate school. By bridging molecular concepts of pathogenesis to the clinical expression of disease in cell, tissue and organ, this fully updated, introductory reference provides the background necessary for an understanding of today’s advances in pathology and medicine. Explains the practice of "molecular medicine" and the translational aspects of molecular pathology, including molecular diagnostics, molecular assessment and personalized medicine Orients non-pathologists on what pathologists look for and how they interpret their observational findings based on histopathology Provides the reader with what is missing from most targeted introductions to pathology—the cell biology behind pathophysiology

Download or read book Journal of Evolutionary Biochemistry and Physiology written by and published by . This book was released on 1999 with total page 362 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Comparative Enzymology of Cholinesterases written by Serge N. Moralev and published by Internat'l University Line. This book was released on 2007 with total page 522 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Inventory of Energy Research and Development 1973 1975 written by Oak Ridge National Laboratory and published by . This book was released on 1976 with total page 1356 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Sidelights on Greek Antiquity written by Konstantinos Kalogeropoulos and published by Walter de Gruyter GmbH & Co KG. This book was released on 2021-03-08 with total page 779 pages. Available in PDF, EPUB and Kindle. Book excerpt: Nineteen contributions by eminent scholars cover topics in Greek Epigraphy, Ancient History, Archaeology, and the Historiography of Archaeology. The section on Epigraphy and Ancient History has a particular focus on Attica, whereas material from Eretria, Delphi, the Argolid, Aetolia, Macedonia, Samothrace, and Aphrodisias widens the picture. The section on Archaeology discusses cultural variation as well as matters of cult, myth, and style, especially in Attica, from the Chalcolithic to the Roman period. The final section on the History of Archaeology reviews the early history of archaeological research at sites such as Piraeus, Rhamnous, Marathon, Oropos, Pylos, and Eretria, based on unpublished archival sources as well as on preliminary sketches and architectural drawings by 19th century artists.

Download or read book The Trypanosomiases written by Ian Maudlin and published by CABI. This book was released on 2004-07-09 with total page 644 pages. Available in PDF, EPUB and Kindle. Book excerpt: This state-of-the-art reference book includes comprehensive coverage of the biology and control of African, Asian and South American trypanosomiasis ("sleeping sickness") in man and animals. It describes recent research developments in the biology and molecular biology of trypanosomes (the protozoan parasite) and their vectors, and methods in diagnosis and control, such as trapping tsetse fly vectors. Different sections of the book are devoted to biology of trypanosomes, vector biology, epidemiology and diagnosis, pathogenesis, disease impact, chemotherapy and disease control, and vector control. The book contains contributions from leading experts from Europe, North and South America, and Africa.

Download or read book Human African Trypanosomiasis Sleeping Sickness written by Christian Burri and published by MDPI. This book was released on 2020-06-17 with total page 280 pages. Available in PDF, EPUB and Kindle. Book excerpt: As it is a goal to eliminate human African trypanosomiasis (HAT; sleeping sickness) as a public health problem by 2020 and interrupt transmission by 2030, this is a good moment to reflect on what we have achieved, what we want to achieve, and what could get in our way. HAT has a reputation for spectacular reappearances, and the latest peak of 40,000 reported and over 300,000 estimated cases only dates back to 1998. Efforts of the WHO and partners as well as the development of simpler and much better-tolerated treatments, improved diagnostics, and vector control tools made it possible to reduce this number by 95%. Case identification and confirmation remain complex and require specific skills, treatment remains error-prone and reports on long-term survivors have emerged, and the relevance of the animal reservoir for T. b. gambiense HAT needs clarification. In addition, to win the “end game” against this massively stigmatized disease, the human factor will play a key role. This Special Issue addresses many of the burning topics about disease elimination in its 12 research and 7 review articles and one case study. The papers critically reflect the approaches used, investigate the mentioned challenges, and propose novel approaches and interventions from various points of view.

Download or read book Mobile DNA III written by Michael Chandler and published by John Wiley & Sons. This book was released on 2020-07-24 with total page 1321 pages. Available in PDF, EPUB and Kindle. Book excerpt: An exploration of the raw power of genetic material to refashion itself to any purpose... Virtually all organisms contain multiple mobile DNAs that can move from place to place, and in some organisms, mobile DNA elements make up a significant portion of the genome. Mobile DNA III provides a comprehensive review of recent research, including findings suggesting the important role that mobile elements play in genome evolution and stability. Editor-in-Chief Nancy L. Craig assembled a team of multidisciplinary experts to develop this cutting-edge resource that covers the specific molecular mechanisms involved in recombination, including a detailed structural analysis of the enzymes responsible presents a detailed account of the many different recombination systems that can rearrange genomes examines the tremendous impact of mobile DNA in virtually all organisms Mobile DNA III is valuable as an in-depth supplemental reading for upper level life sciences students and as a reference for investigators exploring new biological systems. Biomedical researchers will find documentation of recent advances in understanding immune-antigen conflict between host and pathogen. It introduces biotechnicians to amazing tools for in vivo control of designer DNAs. It allows specialists to pick and choose advanced reviews of specific elements and to be drawn in by unexpected parallels and contrasts among the elements in diverse organisms. Mobile DNA III provides the most lucid reviews of these complex topics available anywhere.

Download or read book Stochastic Optimal Control in Infinite Dimension written by Giorgio Fabbri and published by Springer. This book was released on 2017-06-22 with total page 928 pages. Available in PDF, EPUB and Kindle. Book excerpt: Providing an introduction to stochastic optimal control in infinite dimension, this book gives a complete account of the theory of second-order HJB equations in infinite-dimensional Hilbert spaces, focusing on its applicability to associated stochastic optimal control problems. It features a general introduction to optimal stochastic control, including basic results (e.g. the dynamic programming principle) with proofs, and provides examples of applications. A complete and up-to-date exposition of the existing theory of viscosity solutions and regular solutions of second-order HJB equations in Hilbert spaces is given, together with an extensive survey of other methods, with a full bibliography. In particular, Chapter 6, written by M. Fuhrman and G. Tessitore, surveys the theory of regular solutions of HJB equations arising in infinite-dimensional stochastic control, via BSDEs. The book is of interest to both pure and applied researchers working in the control theory of stochastic PDEs, and in PDEs in infinite dimension. Readers from other fields who want to learn the basic theory will also find it useful. The prerequisites are: standard functional analysis, the theory of semigroups of operators and its use in the study of PDEs, some knowledge of the dynamic programming approach to stochastic optimal control problems in finite dimension, and the basics of stochastic analysis and stochastic equations in infinite-dimensional spaces.

Download or read book Civil Affairs Handbook written by United States. Army Service Forces and published by . This book was released on 1944 with total page 142 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Whose Urban Renaissance written by Libby Porter and published by Routledge. This book was released on 2009-01-13 with total page 374 pages. Available in PDF, EPUB and Kindle. Book excerpt: The desire of governments for a 'renaissance' of their cities is a defining feature of contemporary urban policy. From Melbourne and Toronto to Johannesburg and Istanbul, government policies are successfully attracting investment and middle-class populations to their inner areas. Regeneration - or gentrification as it can often become - produces winners and losers. There is a substantial literature on the causes and unequal effects of gentrification, and on the global and local conditions driving processes of dis- and re-investment. But there is little examination of the actual strategies used to achieve urban regeneration - what were their intents, did they 'succeed' (and if not why not) and what were the specific consequences? Whose Urban Renaissance? asks who benefits from these urban transformations. The book contains beautifully written and accessible stories from researchers and activists in 21 cities across Europe, North and South America, Asia, South Africa, the Middle East and Australia, each exploring a specific case of urban regeneration. Some chapters focus on government or market strategies driving the regeneration process, and look closely at the effects. Others look at the local contingencies that influence the way these strategies work. Still others look at instances of opposition and struggle, and at policy interventions that were used in some places to ameliorate the inequities of gentrification. Working from these stories, the editors develop a comparative analysis of regeneration strategies, with nuanced assessments of local constraints and counteracting policy responses. The concluding chapters provide a critical comparison of existing strategies, and open new directions for more equitable policy approaches in the future. Whose Urban Renaissance? is targeted at students, academics, planners, policy-makers and activists. The book is unique in its geographical breadth and its constructive policy emphasis, offering a succinct, critical and timely exploration of urban regeneration strategies throughout the world.

Download or read book Audit Report written by and published by . This book was released on 1995 with total page 560 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Encyclopedia of Microbiology Four Volume Set written by Martin Alexander and published by Academic Press. This book was released on 2000-02-10 with total page 963 pages. Available in PDF, EPUB and Kindle. Book excerpt: The First Edition of the Encyclopedia of Microbiology was hailed by leading scientists and researchers around the world as "excellent," "outstanding," and "impressive." This Second Edition will serve as an up-to-date version of this reference which has been useful to academic, industrial, and personal libraries for years. The Encyclopedia of Microbiology, Second Edition both challenges and stimulates the reader, and illustrates the importance of microbiology, a field that cannot be over emphasized in this booming biotechnology age. Key Features * Completely redesigned and revised approach with 65% new material * Contains approximately 300 articles, 1000 illustrations, and 400 tables * New design includes thematic table of contents, combined glossary of terms, and appendix * Provides color plate sections in each volume * 17 subject areas, including exciting coverage of microbes in extreme environments and microbes in emerging infections

Download or read book Parasitic Protozoa written by and published by Academic Press. This book was released on 2012-12-02 with total page 344 pages. Available in PDF, EPUB and Kindle. Book excerpt: Updated and much expanded, the Second Edition of Parasitic Protozoa is designed to be useful to physicians, veterinarians, and research scientists concerned with diseases caused by protozoa in man, and in domestic and wild animals including fish, mollusks and insects, as well as the more commonly considered vertebrate animals. Each section contains information on disease pathogens, treatment, diagnosis, and epidemiology of the diseases caused by the various protozoans. The book is not limited to these medically-oriented subjects, but treats taxonomy, morphology, and metabolism of the organisms in such a way as to be of interest to scientists and graduate students working in the field of protozoology. The entire edition, published in ten volumes, is arranged so that subjects of common interest occupy individual volumes.