Download or read book Hormonally Active Agents in the Environment written by National Research Council and published by National Academies Press. This book was released on 2000-02-03 with total page 453 pages. Available in PDF, EPUB and Kindle. Book excerpt: Some investigators have hypothesized that estrogens and other hormonally active agents found in the environment might be involved in breast cancer increases and sperm count declines in humans as well as deformities and reproductive problems seen in wildlife. This book looks in detail at the science behind the ominous prospect of "estrogen mimics" threatening health and well-being, from the level of ecosystems and populations to individual people and animals. The committee identifies research needs and offers specific recommendations to decision-makers. This authoritative volume: Critically evaluates the literature on hormonally active agents in the environment and identifies known and suspected toxicologic mechanisms and effects of fish, wildlife, and humans. Examines whether and how exposure to hormonally active agents occursâ€"in diet, in pharmaceuticals, from industrial releases into the environmentâ€"and why the debate centers on estrogens. Identifies significant uncertainties, limitations of knowledge, and weaknesses in the scientific literature. The book presents a wealth of information and investigates a wide range of examples across the spectrum of life that might be related to these agents.
Download or read book Environmental Toxicants written by Morton Lippmann and published by John Wiley & Sons. This book was released on 2009-03-26 with total page 1189 pages. Available in PDF, EPUB and Kindle. Book excerpt: Provides the most current information and research available for performing risk assessments on exposed individuals and populations, giving guidance to public health authorities, primary care physicians, and industrial managers Reviews current knowledge on human exposure to selected chemical agents and physical factors in the ambient environment Updates and revises the previous edition, in light of current scientific literature and its significance to public health concerns Includes new chapters on: airline cabin exposures, arsenic, endocrine disruptors, and nanoparticles
Download or read book Endocrine Toxicology written by J. Charles Eldridge and published by CRC Press. This book was released on 2016-04-19 with total page 424 pages. Available in PDF, EPUB and Kindle. Book excerpt: With contributions by international experts in academia, chemical manufacturing, government research laboratories, regulatory agencies, and private consulting, this guide explores the potentially damaging influence of environmental agents on the endocrine system. It examines endocrine toxicology's increased importance in environmental safety issues
Download or read book Challenges in Endocrine Disruptor Toxicology and Risk Assessment written by Alberto Mantovani and published by Royal Society of Chemistry. This book was released on 2020-12-08 with total page 539 pages. Available in PDF, EPUB and Kindle. Book excerpt: Insight into the role of hormones, particularly estrogen and testosterone, in health and disease etiology – including interactions with other hormone pathways – has dramatically changed. Estrogen and androgen receptors, with their polymorphisms, are key molecules in all tissues and are involved in a number of homeostatic mechanisms but also pathological processes including carcinogenesis and the development of metabolic and neurological disorders such as diabetes and Alzheimer’s disease. Endocrine disrupting chemicals (EDCs) can interfere with the endocrine (hormone) systems at certain dosages and play a key role in the pathology of disease. Most known EDCs are manmade and are therefore an increasing concern given the number commonly found in household products and the environment. This book will cover the mechanisms of EDC pathology across the spectrum of disease, as well as risk assessment and government and legal regulation to provide a holistic view of the current issues and cutting-edge research in the topic. With contributions from global leaders in the field, this book will be an ideal reference for toxicologists, endocrinologists and researchers interested in developmental biology, regulatory toxicology and the interface between environment and human health.
Download or read book Environmental Endocrine Toxicants written by Younis Ahmad Hajam and published by CRC Press. This book was released on 2023-08-04 with total page 429 pages. Available in PDF, EPUB and Kindle. Book excerpt: Highlighting cutting-edge research on human exposure to endocrine toxicants and the related harmful effects, this book focuses on the challenges of dealing with increasing pollution levels, increased use of synthetic chemicals, and environmental endocrine disruptors that endanger the human endocrine system and its hormones. Found in manmade and natural substances and materials, these toxicants include pesticides, herbicides, industrial chemicals, solvents and byproducts, phytoestrogens, nanomaterials, and chemicals used in personal care products. They may mimic or interfere with the body’s hormones and are linked with developmental, reproductive, brain, immune, and other problems. The volume discusses the chemical nature and mechanisms of endocrine disruptors, their sources, the impact of endocrine toxicants on a sustainable environment, and the effect of endocrine toxicants on human health, such as on thyroid glands, on human reproduction, etc. The volume also looks at the therapeutic effects of medicinal plants on endocrine disorders in humans.
Download or read book Environmental Toxicology written by Ming-Ho Yu and published by CRC Press. This book was released on 2004-10-28 with total page 367 pages. Available in PDF, EPUB and Kindle. Book excerpt: An Indispensable Reference of Air, Soil, and Water Pollutants This second edition of Environmental Toxicology focuses on the biological and health effects toxins have on living organisms. It also stresses the relationship between human activity and the environment, relating changes in the environment with the changing patterns of human d
Download or read book Environmental Toxicology written by Ming-Ho Yu and published by CRC Press. This book was released on 2000-06-27 with total page 278 pages. Available in PDF, EPUB and Kindle. Book excerpt: How are pollutants transformed after their release into the environment? How are organisms exposed, and how do physiological alterations impact population dynamics and community structure? What direct or indirect impacts occur? As early as the 50s and 60s people living near industrial plants began to recognize undesirable changes in their environment - and to ask these very questions. The discipline of environmental toxicology addresses these questions. Written by an expert with over twenty years experience, Environmental Toxicology covers the physiological and toxicological effects of environmental toxicants on living systems. It explores the sources, and the physical and chemical characteristics of toxicants. It goes further to highlight their impact on plants, animals, and humans. The author furnishes information on the mechanism of action of individual chemicals and chemical combinations including cellular damage at the molecular level. He defines environmental toxicology and discusses the relationship between human activities and their impacts on living systems. He furnishes an overview of our changing environment and the possible link between that environment and the changing pattern of human diseases. Environmental Toxicology provides fundamental knowledge on the toxicological effects of environmental chemicals on living systems. Its fifteen chapters cover the occurrence of toxicants, air pollution, environmental metals, pesticides and related materials such as PCBs and dioxins, mutagenesis, and environmental cancer. This useful resource will enhance your knowledge of the impacts of environmental toxicants on living organisms.
Download or read book Temperature and Toxicology written by Christopher J. Gordon and published by CRC Press. This book was released on 2005-02-28 with total page 358 pages. Available in PDF, EPUB and Kindle. Book excerpt: Thermoregulation is vital for survival but the interplay between toxic insults and thermoregulatory mechanisms is often poorly understood. Temperature and Toxicology: An Integrative, Comparative, and Environmental Approach is the first major text to study the integrative thermoregulatory responses of mammals that are exposed to toxicants. Because e
Download or read book Zebrafish Protocols for Neurobehavioral Research written by Allan V. Kalueff and published by Humana Press. This book was released on 2012-06-06 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Zebrafish (Danio rerio) play an integral role in biomedical research, enabling researchers to examine physiological mechanisms and pathways relevant to human pathogenesis and its therapy. That, along with their low cost, easy manipulation, short reproductive cycles, and physiological homology to humans, has made zebrafish a vital model organism for neuroscience research. Zebrafish Protocols for Neurobehavioral Research addresses protocols for both larval and adult models, written by the leading experts in the field of zebrafish research. Part I of this book takes advantage of the high-throughput nature of larval models to offer protocols for research requiring high output, easily manipulated screens. The second half of the book focuses on the robust and sophisticated behaviors of adult zebrafish, suitable for the neurophenotyping of complex traits and multi-domain disorders. Importantly, these models complement each other, working together to provide researchers with valuable insights into neurobiology of normal and pathological behavior. Thorough and cutting-edge, this volume is a useful, authoritative reference guide that should hold a coveted spot in zebrafish laboratories across the globe.
Download or read book A Handbook of Environmental Toxicology written by J.P.F. D'Mello and published by CABI. This book was released on 2019-12-04 with total page 675 pages. Available in PDF, EPUB and Kindle. Book excerpt: Written by an international team of authors from a range of educational, medical and research establishments, this book is an essential reference for advanced students and researchers in the areas of environmental sciences, ecology, agriculture, environmental health and medicine, in addition to industry and government personnel responsible for environmental regulations and directives. A Handbook of Environmental Toxicology focuses on two key aspects: human disorders and ecotoxicology as affected by major toxins originating from biological sources and pollutants, as well as radiation generated spontaneously or as a result of anthropogenic activity. A diverse array of these potentially harmful agents regularly appear in the atmosphere, soil, water and food, compromising both human health and biodiversity in natural and managed ecosystems.
Download or read book Preterm Birth written by Institute of Medicine and published by National Academies Press. This book was released on 2007-05-23 with total page 791 pages. Available in PDF, EPUB and Kindle. Book excerpt: The increasing prevalence of preterm birth in the United States is a complex public health problem that requires multifaceted solutions. Preterm birth is a cluster of problems with a set of overlapping factors of influence. Its causes may include individual-level behavioral and psychosocial factors, sociodemographic and neighborhood characteristics, environmental exposure, medical conditions, infertility treatments, and biological factors. Many of these factors co-occur, particularly in those who are socioeconomically disadvantaged or who are members of racial and ethnic minority groups. While advances in perinatal and neonatal care have improved survival for preterm infants, those infants who do survive have a greater risk than infants born at term for developmental disabilities, health problems, and poor growth. The birth of a preterm infant can also bring considerable emotional and economic costs to families and have implications for public-sector services, such as health insurance, educational, and other social support systems. Preterm Birth assesses the problem with respect to both its causes and outcomes. This book addresses the need for research involving clinical, basic, behavioral, and social science disciplines. By defining and addressing the health and economic consequences of premature birth, this book will be of particular interest to health care professionals, public health officials, policy makers, professional associations and clinical, basic, behavioral, and social science researchers.
Download or read book Reducing Environmental Cancer Risk written by Suzanne H. Reuben and published by DIANE Publishing. This book was released on 2010-10 with total page 240 pages. Available in PDF, EPUB and Kindle. Book excerpt: Though overall cancer incidence and mortality have continued to decline in recent years, cancer continues to devastate the lives of far too many Americans. In 2009 alone, 1.5 million American men, women, and children were diagnosed with cancer, and 562,000 died from the disease. There is a growing body of evidence linking environmental exposures to cancer. The Pres. Cancer Panel dedicated its 2008¿2009 activities to examining the impact of environmental factors on cancer risk. The Panel considered industrial, occupational, and agricultural exposures as well as exposures related to medical practice, military activities, modern lifestyles, and natural sources. This report presents the Panel¿s recommend. to mitigate or eliminate these barriers. Illus.
Download or read book Ecological Impacts of Toxic Chemicals written by Francisco Sánchez-Bayo, Paul J. van den Brink, Reinier M. Mann and published by Francisco Sanchez-Bayo. This book was released on 2011-09-09 with total page 288 pages. Available in PDF, EPUB and Kindle. Book excerpt: Ecological Impacts of Toxic Chemicals presents a comprehensive, yet readable account of the known disturbances caused by all kinds of toxic chemicals on both aquatic and terrestrial ecosystems. Topics cover the sources of toxicants, their fate and distribution through the planet, their impacts on specific ecosystems, and their remediation by natural systems. Each chapter is written by well-known specialists in those areas, for the general public, students, and even scientists from outside this field. The book intends to raise awareness of the dangers of chemical pollution in a world dominated by industry and globalization of resources. Because the problems are widespread and far reaching, it is hoped that confronting the facts may prompt better management practices at industrial, agricultural and all levels of management, from local to governmental, so as to reduce the negative impacts of chemical contaminants on our planet.
Download or read book Endocrine Disruption and Human Health written by Philippa D. Darbre and published by Academic Press. This book was released on 2015-03-21 with total page 390 pages. Available in PDF, EPUB and Kindle. Book excerpt: Endocrine Disruption and Human Health starts with an overview of what endocrine disruptors are, the issues surrounding them, and the source of these chemicals in the ecosystem. This is followed by an overview of the mechanisms of action and assay systems. The third section includes chapters written by specialists on different aspects of concern for the effects of endocrine disruption on human health. Finally, the authors consider the risk assessment of endocrine disruptors and the pertinent regulation developed by the EU, the US FDA, as well as REACH and NGOs. The book has been written for researchers and research clinicians interested in learning about the actions of endocrine disruptors and current evidence justifying concerns for human health but is useful for those approaching the subject for the first time, graduate students, and advanced undergraduate students. - Provides readers with access to a range of information from the basic mechanisms and assays to cutting-edge research investigating concerns for human health - Presents a comprehensive, translational look at all aspects of endocrine disruption and its effects on human health - Offers guidance on the risk assessment of endocrine disruptors and current relevant regulatory considerations
Download or read book XIIIth International Symposium on Spermatology written by Lars Björndahl and published by Springer Nature. This book was released on 2021-07-22 with total page 370 pages. Available in PDF, EPUB and Kindle. Book excerpt: These proceedings of the 2018 XIII International Symposium on Spermatology focus on comparative biology, and encourages discussion and the exchange of ideas. The aim of this Symposium was to provide a unique opportunity and bring together scientists from a wide spectrum of research fields – human, domestic animals and other mammals, vertebrates, insects, and plants. The underlying focus is on the function of the spermatozoon – a common feature for sexual reproduction, but extremely varied. By exploring the variability, a better understanding of male reproductive functions can develop. These proceedings address the mechanisms of physiology and pathophysiology, rather than diagnosis and treatment. The symposium featured keynote lectures by invited speakers, followed by presentations on specific aspects of the general topic of the session. Experimental studies are given priority over clinical studies of patient populations. The proceedings comprise both keynote speakers' texts and selected free communications. Posters were considered for publication in the proceedings, and the volume includes exhibited materials on the work of prominent spermatologists, highlighting their important past achievements in the field.
Download or read book Ecosystems and Human Health written by Richard B. Philp and published by CRC Press. This book was released on 2013-03-27 with total page 441 pages. Available in PDF, EPUB and Kindle. Book excerpt: Since the second edition of this text was published, many new environmental incidents have occurred, including another nuclear disaster, a mine disaster in the United States, and the Gulf of Mexico oil spill. Updated throughout the text, Ecosystems and Human Health: Toxicology and Environmental Hazards, Third Edition explores the broad range of environmental and human health aspects of chemical and biological hazards—from natural toxins and disasters to man-made pollutants and environmental crises. The book begins with the basic principles of pharmacology and toxicology, risk analysis, and air, water, and soil pollution. It then examines various toxicants and hazards, such as airborne hazards, halogenated hydrocarbons, metals, and organic solvents. Chapters also discuss food additives and contaminants, pesticides, hormone disrupters, radiation hazards, and natural environmental hazards such as venomous and toxic animals. The text reviews the Chernobyl nuclear crisis and the Walkerton drinking water tragedy, as well as other disasters, assessing some of their long-term effects, now that sufficient time has elapsed since their occurrence. With updates in every chapter, this third edition contains significant expansion of information on the genetics of chemical carcinogenesis, global warming, food additives, invasive species in the Great Lakes, nuclear accidents, and more. The book describes how chemical toxins and biological hazards can impact the environment and the people who live in it. The author presents numerous examples of the relationship between ecosystem health and human health. He emphasizes the need to consider the environmental impact of human activities and includes many real-world examples and new case studies.
Download or read book Endocrine Disrupting Chemicals written by Andrea C. Gore and published by Springer Science & Business Media. This book was released on 2007-06-08 with total page 361 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book provides comprehensive coverage of the three most important themes in the field of Endocrine Disrupting Chemicals (EDC) research: the basic biology of EDCs, particularly their effects on reproductive systems; EDC effects on humans and wildlife, including biomedical considerations; and potential interventions and practical advice for dealing with the problem of EDCs.
