Download or read book Engineering the Knee Meniscus written by Kyriacos A. Athanasiou and published by Morgan & Claypool Publishers. This book was released on 2009 with total page 98 pages. Available in PDF, EPUB and Kindle. Book excerpt: The knee meniscus was once thought to be a vestigial tissue, but is now known to be instrumental in imparting stability, shock absorption, load transmission, and stress distribution within the knee joint. Unfortunately, most damage to the meniscus cannot be effectively healed by the body. Meniscus tissue engineering offers a possible solution to this problem by striving to create replacement tissue that may be implanted into a defect site. With a strong focus on structure-function relationships, this book details the essential anatomical, biochemical, and mechanical aspects of this versatile tissue and reviews current meniscus tissue engineering strategies and repair techniques. We have written this text such that undergraduate students, graduate students, and researchers will find it useful as a first foray into tissue engineering, a cohesive study of the meniscus, or a reference for meniscus engineering specifications. Table of Contents: Structure-Function Relationships of the Knee Meniscus / Pathophysiology and the Need for Tissue Engineering / Tissue Engineering of the Knee Meniscus / Current Therapies and Future Directions

Download or read book Engineering the Knee Meniscus written by Kyriacos Athanasiou and published by Springer Nature. This book was released on 2022-05-31 with total page 90 pages. Available in PDF, EPUB and Kindle. Book excerpt: The knee meniscus was once thought to be a vestigial tissue, but is now known to be instrumental in imparting stability, shock absorption, load transmission, and stress distribution within the knee joint. Unfortunately, most damage to the meniscus cannot be effectively healed by the body. Meniscus tissue engineering offers a possible solution to this problem by striving to create replacement tissue that may be implanted into a defect site. With a strong focus on structure-function relationships, this book details the essential anatomical, biochemical, and mechanical aspects of this versatile tissue and reviews current meniscus tissue engineering strategies and repair techniques. We have written this text such that undergraduate students, graduate students, and researchers will find it useful as a first foray into tissue engineering, a cohesive study of the meniscus, or a reference for meniscus engineering specifications. Table of Contents: Structure-Function Relationships of the Knee Meniscus / Pathophysiology and the Need for Tissue Engineering / Tissue Engineering of the Knee Meniscus / Current Therapies and Future Directions

Download or read book In Vivo Tissue Engineering of the Knee Joint Meniscus written by Tony George Tienen and published by . This book was released on 2004 with total page 160 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Meniscus of the Knee written by Taiceer Abdulwahab and published by BoD – Books on Demand. This book was released on 2019-06-19 with total page 108 pages. Available in PDF, EPUB and Kindle. Book excerpt: The principal aim of this title is to provide the arthroscopic orthopaedic surgeon with a clear, concise account of the anatomy, pathology, conservative and operative surgical techniques in the management of meniscal pathology. Meniscal lesions are extremely common, and arthroscopic meniscal surgery is one of the most common orthopaedic surgical procedures performed. The art of meniscal surgery involves many steps, with ever-evolving techniques and implants. This book has been prepared during a period of widespread debate on, and evolution in, the conservative, surgical, and biological techniques for managing meniscal lesions. This text will help consolidate the current evidence to enable the development of optimal management plans for meniscal injuries.

Download or read book The Meniscus written by Philippe Beaufils and published by Springer Science & Business Media. This book was released on 2010-04-28 with total page 397 pages. Available in PDF, EPUB and Kindle. Book excerpt: This guide focuses on the normal meniscal mechanism, body and function. Meniscal pathology and therapy are depicted in detail, followed by a presentation of long-term experience of meniscal transplantation and a look into the future of meniscal surgery.

Download or read book Bio Engineered Meniscus for Tissue Engineering written by Azran Azhim and published by . This book was released on 2019 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Meniscus plays fundamental roles in the knee mechanisms and functions. It acts as a shock absorber where it enables even distribution of forces, and also lubricates knee joints. Meniscal injuries could result to the onset of degenerative osteoarthritis if proper treatments are delayed. To date, treatment of meniscal injuries are more towards conservative methods and surgical approach commonly known as meniscectomy. Attempts to develop scaffolds for meniscus implants from synthetic and biological sources have been done in the recent years. This approach involves a multidisciplinary study known as tissue engineering and regenerative medicine. It involves the combination of three crucial aspects; the choice of chondrogenic/stem cells, bioscaffolds and favourable environmental factors such as growth factors. This chapter discusses and highlights on the currently available meniscal scaffolds that have been explored before. Focus is also directed on the potential of decellularized extracellular matrix (ECM), prepared through sonication treatment that produced scaffolds which mimics natural meniscus. The evaluation of decellularized scaffolds was portrayed through recellularization using cells namely chondrocytes, fibrochondrocytes and stem cells in order to regenerate new functional tissue. In short, this chapter serves as a representation of current approaches aiming in bio-engineering the meniscal scaffolds as meniscus tissue replacement.

Download or read book The Role of the Meniscus in Knee Joint Load Transmission written by Catherine Mary Ford and published by . This book was released on 1992 with total page 226 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Meniscus Injuries An Issue of Clinics in Sports Medicine E Book written by Brett D. Owens and published by Elsevier Health Sciences. This book was released on 2019-12-03 with total page 241 pages. Available in PDF, EPUB and Kindle. Book excerpt: This issue of Clinics in Sports Medicine will provide a comprehensive review of Meniscus Injuries. Guest edited by Drs. Brett Owens and Ramin Tabaddor, this issue will discuss a number of related topics that are important to practicing clinicians. This issue is one of four selected each year by our series Consulting Editor, Dr. Mark Miller. The volume will include articles on: Meniscus Form and Function, Epidemiology of Meniscus Injury, Meniscus Repair Techniques, Meniscus Root Repair, Meniscus Ramp Lesions, Partial Meniscus Replacement, Meniscus Allograft Transplantation, Meniscus Regenerative Basic Science, Rehabilitation Following Meniscus Repair, Return to Play Following Meniscus Repair, Role of Alignment and Osteotomy in Meniscus Pathology, among others.

Download or read book Meniscal Injuries written by John D. Kelly, IV and published by Springer Science & Business Media. This book was released on 2013-09-20 with total page 141 pages. Available in PDF, EPUB and Kindle. Book excerpt: Thoroughly discussing the varied elements of meniscal damage and repair, Meniscal Injuries: Management and Surgical Techniques includes the insights and expertise of over 20 leading surgeons and researchers on topics ranging from meniscal anatomy, physical examination, innovative resection and repair techniques, gene therapy, and tissue regeneration. This treatise offers wisdom aimed at assessing true surgical candidates, exploring the intricacies of meniscal composition and function, an overview of meniscal scaffolds and replacements, and patient examination pearls. Also discussed in depth is cutting edge research concerning meniscal repair enhancement, nanofiber technology as a means of meniscal replacement, and biologic agents directed toward chondral protection. All the science presented will direct the sports medicine practitioner to state-of-the-art treatment aimed at knee preservation. Meniscal repair and regeneration is a rapidly evolving science - early attempts at meniscal restoration or repair resulted in short-term gains which often sacrificed long-term joint integrity. Now, the practitioner is afforded numerous means of retaining or restoring meniscal tissue. Breakthroughs in scaffold and allograft replacement, as featured herein, offer the promise of articular cartilage preservation like never before. In addition, tissue regeneration and gene therapy techniques, featured throughout, offer a glimpse into emerging technologies aimed at preserving or replacing meniscal tissue in previously considered “hopeless” cases. As such, Meniscal Injuries will be an indispensible resource to orthopedic surgeons and sports medicine practitioners interested in providing the absolute most contemporary and evidence-based care to their patients.

Download or read book Load bearing Role of the Human Knee Meniscus written by Gregory Alexander Brown and published by . This book was released on 1990 with total page 520 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Sports Injuries written by Mahmut Nedim Doral and published by Springer Nature. This book was released on 2015-06-29 with total page 3295 pages. Available in PDF, EPUB and Kindle. Book excerpt: Sports Injuries: Prevention, Diagnosis, Treatment and Rehabilitation covers the whole field of sports injuries and is an up-to-date guide for the diagnosis and treatment of the full range of sports injuries. The work pays detailed attention to biomechanics and injury prevention, examines the emerging treatment role of current strategies and evaluates sports injuries of each part of musculoskeletal system. In addition, pediatric sports injuries, extreme sports injuries, the role of physiotherapy, and future developments are extensively discussed. All those who are involved in the care of patients with sports injuries will find this textbook to be an invaluable, comprehensive, and up-to-date reference.

Download or read book Meniscal Transplantation written by René Verdonk and published by Springer Science & Business Media. This book was released on 2013-05-16 with total page 117 pages. Available in PDF, EPUB and Kindle. Book excerpt: Meniscal transplantation has become an attractive option in selected patients with incapacitating knee pain. This book discusses all aspects of meniscal transplantation, covering the use of both allografts and meniscal substitutes, including collagen and polyurethane implants. Acknowledged experts in the field review the basic science, explain indications, and describe surgical techniques and the results achieved to date. All the material is up to date, with information on new implants, new techniques, and new surgical approaches. Future trends in the treatment of meniscal lesions are also discussed as we move towards the application of regenerative strategies to restore meniscus function. ​

Download or read book A Finite Element Model of the Human Knee Joint for the Study of Meniscal Replacements written by Tammy Lynn Haut Donahue and published by . This book was released on 2000 with total page 322 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Regenerative Strategies for the Treatment of Knee Joint Disabilities written by Joaquim Miguel Oliveira and published by Springer. This book was released on 2016-09-26 with total page 406 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book presents regenerative strategies for the treatment of knee joint disabilities. The book is composed of four main sections totaling 19 chapters which review the current knowledge on the clinical management and preclinical regenerative strategies. It examines the role of different natural-based biomaterials as scaffolds and implants for addressing different tissue lesions in the knee joint. Section one provides an updated and comprehensive discussion on articular cartilage tissue regeneration. Section two focuses on the important contributions for bone and osteochondral tissue engineering. Section three overview the recent advances on meniscus repair/regeneration strategies. Finally, section four further discusses the current strategies for treatment of ligament lesions. Each chapter is prepared by world know expert on their fields, so we do firmly believe that the proposed book will be a reference in the area of biomaterials for regenerative medicine.

Download or read book Imaging of Arthritis and Metabolic Bone Disease E Book written by Barbara N. W. Weissman and published by Elsevier Health Sciences. This book was released on 2009-05-09 with total page 770 pages. Available in PDF, EPUB and Kindle. Book excerpt: Get state-of-the-art coverage of the full range of imaging techniques available to assist in the diagnosis and therapeutic management of rheumatic diseases. Written by acknowledged experts in musculoskeletal imaging, this richly illustrated, full-color text presents the latest diagnostic and disease monitoring modalities - MRI, CT, ultrasonography, nuclear medicine, DXA — as well as interventional procedures. You'll find comprehensive coverage of specific rheumatic conditions, including osteoarticular and extraarticular findings. This superb new publication puts you at the forefront of imaging in arthritis and metabolic bone disease — a must have reference for the clinician and imaging specialist. Includes all imaging modalities relevant to rheumatic disease, and applications and contraindications of each, for balanced coverage. Incorporates a user-friendly, consistent full-color format for quick and easy reference. Provides osteoarticular and extra-articular features and findings to show how imaging benefits diagnosis and management of complex rheumatologic conditions. Creates a one-stop shop with comprehensive coverage of imaging for all rheumatic conditions, including metabolic conditions and pediatric disorders. Presents interventional techniques—injections, arthrography, radiofrequency ablation—to create the perfect diagnostic and interventional clinical tool.

Download or read book Knee Meniscus written by Van C. Mow and published by . This book was released on 1992 with total page 204 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Enhancing the Biochemical and Mechanical Properties of a Self assembling Scaffold free Tissue Engineered Knee Meniscus written by Pasha Hadidi and published by . This book was released on 2014 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt: Damage to the fibrocartilage of the knee meniscus leads to nearly 1 million procedures annually in the U.S. and Europe, comprising the single most common source of procedures performed by orthopedic surgeons. Although the knee meniscus is frequently injured due to trauma, age, or disease, this tissue is avascular and thus possesses little healing capacity. Because of this, the knee meniscus is a prime candidate for tissue engineering, and recent advances in the field have brought about a range of new approaches. In particular, scaffold-free and self-organizing methods of tissue synthesis have been gaining attention in recent years. This thesis will investigate the application of novel stimuli, both singularly and in combination, with respect to a recently pioneered scaffold-free technique: the self-assembling process. The global objective of this work was to enhance the mechanical properties, biochemical content, and extracellular matrix (ECM) organization of self-assembling knee meniscus fibrocartilage. Towards addressing this objective, this thesis 1) identified a novel stimulus which increased tensile properties of engineered tissues through a new mechanism, 2) characterized the process of tissue formation in the self-assembling process temporally and under a variety of initial conditions, and 3) engineered shape-specific knee meniscus constructs using a combination of ECM modulating agents. When assessing a novel stimulus with which to treat self-assembling tissues, a 1.8-fold increase in tensile properties was achieved, along with beneficial improvements in tissue anisotropy. When a variety of initial seeding densities was investigated, a critical seeding density with superior mechanical and biochemical properties was found, which increased tissue properties by up to 11.8-fold over the historical control while using fewer cells than previously needed. Finally, the application of multiple biophysical agents at a lower seeding density led to a synergistic and additive increases in engineered tissue construct properties, including a 3.8-fold increase in tensile modulus to 3.4 MPa, a 3.2-fold increase in collagen cross-link content to 180 nmol/μg, and a 1.7-fold increase in average collagen fiber diameter to 95 nm. Overall, this thesis underscored the potential for novel biophysical agents to be applied separately and in conjunction to enhance the properties of engineered tissues, and paves the way for future investigations of these agents in scaffold-free and scaffold-based tissue engineering studies.