Download or read book Engineered Living Materials written by Wil V. Srubar III and published by Springer Nature. This book was released on 2022-02-16 with total page 219 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book will serve as a primer for readers to understand recent advances, applications, and current challenges in the field of Engineered Living Materials. The chapters cover core science and engineering research areas, including (1) advances in synthetic biology and genetic programmability for Engineered Living Materials, (2) functional Engineered Living Material for application in energy, electronics, and construction, and (3) novel manufacturing approaches for Engineered Living Materials at multiple scales. The emerging field of Engineered Living Materials represents a significant paradigm shift in materials design and synthesis, in which living cells are used to impart biologically active functionalities to manmade materials. The result is a genetically programmable augmentation of non-living matter to exhibit unprecedented life-like (i.e., living) capabilities. At the intersection of synthetic biology and materials science, the field of Engineered Living Materials exhibits unprecedented promise and potential to alter the way we synthesize new materials and design medical devices, fabrics, robotics, commodity polymers, and construction materials. Materials with attributes of living systems can be engineered with an ability to respond to their environment and designed to self-repair in response to physical or other stresses or detect the presence of specific stimuli, such as light, heat, pressure, or hazardous chemical compounds. Although nascent, scientists and researchers in the field of Engineered Living Materials have made marked advances in demonstrating a potential to revolutionize a multitude of science and engineering disciplines. This volume will define the current state of the art of Engineered Living Materials, and highlight grand opportunities and challenges that abound at the nexus of synthetic biology and materials science and engineering.
Download or read book Synthetic Biology Approaches for Engineered Living Materials written by Charles Gilbert and published by . This book was released on 2018 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Biofabrication written by Ritu Raman and published by MIT Press. This book was released on 2021-09-14 with total page 218 pages. Available in PDF, EPUB and Kindle. Book excerpt: How engineered materials and machines powered by living biological cells can tackle technological challenges in medicine, agriculture, and global security. You are a biological machine whose movement is powered by skeletal muscle, just as a car is a machine whose movement is powered by an engine. If you can be built from the bottom up with biological materials, other machines can be as well. This is the conceptual starting point for biofabrication, the act of building with living cells--building with biology in the same way we build with synthetic materials. In this volume in the MIT Press Essential Knowledge series, Ritu Raman offers an accessible introduction to biofabrication, arguing that it can address some of our greatest technological challenges. After presenting the background information needed to understand the emergence and evolution of biofabrication and describing the fundamental technology that enables building with biology, Raman takes deep dives into four biofabrication applications that have the potential to affect our daily lives: tissue engineering, organs-on-a-chip, lab-grown meat and leather, and biohybrid machines. Organs-on-a-chip (devices composed of miniature model tissues), for example, could be used to test new medicine and therapies, and lab-grown meat could alleviate environmental damage done by animal farming. She shows that biological materials have abilities synthetic materials do not, including the ability to adapt dynamically to their environments. Exploring the principles of biofabrication, Raman tells us, should help us appreciate the beauty, adaptiveness, and persistence of the biological machinery that drives our bodies and our world.
Download or read book Biomaterials Artificial Organs and Tissue Engineering written by L Hench and published by Elsevier. This book was released on 2005-09-27 with total page 298 pages. Available in PDF, EPUB and Kindle. Book excerpt: Maintaining quality of life in an ageing population is one of the great challenges of the 21st Century. This book summarises how this challenge is being met by multi-disciplinary developments of specialty biomaterials, devices, artificial organs and in-vitro growth of human cells as tissue engineered constructs. Biomaterials, Artificial Organs and Tissue Engineering is intended for use as a textbook in a one semester course for upper level BS, MS and Meng students. The 25 chapters are organized in five parts: Part one provides an introduction to living and man-made materials for the non-specialist; Part two is an overview of clinical applications of various biomaterials and devices; Part three summarises the bioengineering principles, materials and designs used in artificial organs; Part four presents the concepts, cell techniques, scaffold materials and applications of tissue engineering; Part five provides an overview of the complex socio-economic factors involved in technology based healthcare, including regulatory controls, technology transfer processes and ethical issues. Comprehensive introduction to living and man-made materials Looks at clinical applications of various biomaterials and devices Bioengineering principles, materials and designs used in artificial organs are summarised
Download or read book Living Construction written by Martyn Dade-Robertson and published by Routledge. This book was released on 2020-10-28 with total page 130 pages. Available in PDF, EPUB and Kindle. Book excerpt: Modern biotechnologies give us unprecedented control of the fundamental building blocks of life. For designers, across a range of disciplines, emerging fields such as synthetic biology offer the promise of new sustainable materials and structures which may be grown, are self-assembling, self-healing and adaptable to change. While there is a thriving speculative discourse on the future of design in the age of biotechnology, there are few realized design applications. This book, the first in the Bio Design series, acts as a bridge between design speculation and scientific reality and between contemporary design thinking, in areas such as architecture, product design and fashion design, and the traditional engineering approaches which currently dominate biotechnologies. Filled with real examples, Living Construction reveals how living cells construct and transform materials through methods of fabrication and assembly at multiple scales and how designers can utilize these processes.
Download or read book Materials in the New Millennium written by National Research Council and published by National Academies Press. This book was released on 2001-09-12 with total page 62 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book details the forum that was held by the National Materials Advisory Board at the National Academy of Sciences. The purpose of this forum was to bring the importance of materials to the attention of policy makers and to promote interactions between policy makers and the materials community. Four key themes were addressed: the critical role of materials in advancing technology and enhancing the nation's economy, security, and health, industrial and societal needs that will require materials development in the new millennium. Materials research areas with the greatest potential for meeting those needs, and federal and industrial research initiatives that can help the materials community meet those needs. To help focus this discussion, special sessions were convened to address the current and future roles of materials in four selected areas: information technology, health and biotechnology, national security, and energy and the environment.
Download or read book Engineering Materials for Biomedical Applications written by Swee Hin Teoh and published by World Scientific. This book was released on 2004 with total page 347 pages. Available in PDF, EPUB and Kindle. Book excerpt: The success of any implant or medical device depends very much on the biomaterial used. Synthetic materials (such as metals, polymers and composites) have made significant contributions to many established medical devices. The aim of this book is to provide a basic understanding on the engineering and processing aspects of biomaterials used in medical applications. Of paramount importance is the tripartite relationship between material properties, processing methods and design. As the target audiences cover a wide interdisciplinary field, each chapter is written with a detailed background so that audience of another discipline will be able to understand. For the more knowledgeable reader, a detailed list of references is included.
Download or read book Positioning Synthetic Biology to Meet the Challenges of the 21st Century written by National Research Council and published by National Academies Press. This book was released on 2013-08-05 with total page 81 pages. Available in PDF, EPUB and Kindle. Book excerpt: Synthetic biology-unlike any research discipline that precedes it-has the potential to bypass the less predictable process of evolution to usher in a new and dynamic way of working with living systems. Ultimately, synthetic biologists hope to design and build engineered biological systems with capabilities that do not exist in natural systems-capabilities that may ultimately be used for applications in manufacturing, food production, and global health. Importantly, synthetic biology represents an area of science and engineering that raises technical, ethical, regulatory, security, biosafety, intellectual property, and other issues that will be resolved differently in different parts of the world. As a better understanding of the global synthetic biology landscape could lead to tremendous benefits, six academies-the United Kingdom's Royal Society and Royal Academy of Engineering, the United States' National Academy of Sciences and National Academy of Engineering, and the Chinese Academy of Science and Chinese Academy of Engineering-organized a series of international symposia on the scientific, technical, and policy issues associated with synthetic biology. Positioning Synthetic Biology to Meet the Challenges of the 21st Century summarizes the symposia proceedings.
Download or read book Bioreactor System Design written by Juan A. Asenjo and published by CRC Press. This book was released on 1994-11-17 with total page 644 pages. Available in PDF, EPUB and Kindle. Book excerpt: Describes the state-of-the-art techniques and methods involved in the design, operation, preparation and containment of bioreactor systems, taking into account the interrelated effects of variables associated with both upstream and downstream stages of the design process. The importance of the initial steps in the development of a bioprocess, such as strain and media selection, that have an overwhelming influence on all further operations, is emphasized.;This work is intended for biochemical, chemical and bioprocess engineers; biotechnologists; industrial biochemists; micro- and molecular biologists; food scientists; and upper-level undergraduate and graduate students in these disciplines.
Download or read book Engineered Biomimicry written by Akhlesh Lakhtakia and published by Newnes. This book was released on 2013-05-24 with total page 493 pages. Available in PDF, EPUB and Kindle. Book excerpt: Engineered Biomimicry covers a broad range of research topics in the emerging discipline of biomimicry. Biologically inspired science and technology, using the principles of math and physics, has led to the development of products as ubiquitous as VelcroTM (modeled after the spiny hooks on plant seeds and fruits). Readers will learn to take ideas and concepts like this from nature, implement them in research, and understand and explain diverse phenomena and their related functions. From bioinspired computing and medical products to biomimetic applications like artificial muscles, MEMS, textiles and vision sensors, Engineered Biomimicry explores a wide range of technologies informed by living natural systems. Engineered Biomimicry helps physicists, engineers and material scientists seek solutions in nature to the most pressing technical problems of our times, while providing a solid understanding of the important role of biophysics. Some physical applications include adhesion superhydrophobicity and self-cleaning, structural coloration, photonic devices, biomaterials and composite materials, sensor systems, robotics and locomotion, and ultra-lightweight structures. Explores biomimicry, a fast-growing, cross-disciplinary field in which researchers study biological activities in nature to make critical advancements in science and engineering Introduces bioinspiration, biomimetics, and bioreplication, and provides biological background and practical applications for each Cutting-edge topics include bio-inspired robotics, microflyers, surface modification and more
Download or read book Towards Engineering Living Functional Materials written by Tzu-Chieh Tang (Ph. D.) and published by . This book was released on 2021 with total page 221 pages. Available in PDF, EPUB and Kindle. Book excerpt: Synthetic biology has become one of the most rapidly evolving research fields, with impacts on all aspects of our daily life. Through applying engineering principles to programming biological systems, synthetic biology provides advanced techniques to program organisms to perform desired tasks, similar to machines created by humans. Today, it has enabled the development of alternative meat substitutes, biosensors for water contamination, and living fertilizers that promote plant growth. The grand challenge to bridge the concept-to-product gap is twofold: scalability and safe deployment. First, most model microorganisms cannot produce a macroscale matrix to sustain themselves as standalone devices. The field of engineered living materials (ELMs) aims to recapitulate the remarkable properties of natural biology to create novel, growable, multifunctional materials using genetically engineered organisms. Nevertheless, most relevant pioneering work was created using nano- to microscale biofilm, which has rather small yields and usually requires costly modification. Second, releasing genetically modified microorganisms (GMMs) into the field for food, water, or agricultural applications is often considered risky due to the uncertainty of wild-type organisms acquiring undesirable traits, such as antibiotic resistance, from the GMMs. A significant effort in addressing these unmet needs is called for. This Thesis starts with an introduction of genetic circuits and an in-depth review of the current trends in materials synthetic biology, which includes two major categories of ELMs: self-organizing functional materials and hybrid living materials. The following chapters describe the technologies developed to achieve high scalability and safe deployment of ELMs in these two categories and living devices suitable for real-world applications. Finally, a detailed outlook summarizes the challenges and prospects for materials synthetic biology and engineering living functional materials.
Download or read book Inspired by Biology written by National Research Council and published by National Academies Press. This book was released on 2008-06-17 with total page 170 pages. Available in PDF, EPUB and Kindle. Book excerpt: Scientists have long desired to create synthetic systems that function with the precision and efficiency of biological systems. Using new techniques, researchers are now uncovering principles that could allow the creation of synthetic materials that can perform tasks as precise as biological systems. To assess the current work and future promise of the biology-materials science intersection, the Department of Energy and the National Science Foundation asked the NRC to identify the most compelling questions and opportunities at this interface, suggest strategies to address them, and consider connections with national priorities such as healthcare and economic growth. This book presents a discussion of principles governing biomaterial design, a description of advanced materials for selected functions such as energy and national security, an assessment of biomolecular materials research tools, and an examination of infrastructure and resources for bridging biological and materials science.
Download or read book Living Materials for the Deployment of Genetically Engineered Organisms written by Eleonore Claure Cecilia Tham and published by . This book was released on 2018 with total page 106 pages. Available in PDF, EPUB and Kindle. Book excerpt: The primary objective of this work is to establish an innovative and broad platform to engineer living materials and assemble them into functional devices. First, we assemble bacterial sensor communities into core-shell hydrogel structures to address the major challenge of biocontainment. Biosafety has become a major challenge for synthetic biology tools to transition from laboratory experiments to real applications and prevent potential negative impacts. Genetic and chemical containment strategies have been implemented to restrict the growth and replication of genetically modified organisms while no robust physical containment has been proposed. We developed a hydrogel-based encapsulation technique by leveraging a tough biocompatible shell and genetically recoded organisms to achieve unprecedented containment performance. Then, we implemented biocontainment into wearable hydrogel devices. We use stretchable, robust, and biocompatible hydrogel-elastomer hybrids to host genetically programed bacteria, thus creating a set of stretchable and wearable living materials and devices that possess unprecedented functions and capabilities. Lastly, we genetically encode the formation of biological polymers in E.coli to achieve the self-assembly of bacterial devices. Generating complex biomaterials often requires the coordinated and precise expression of several genes and light induction of biological material formation and patterning offer a powerful toolkit to achieve the necessary degree of precision and control. We leveraged a multichromatic optogenetic control in the bacterium Escherichia coli to express the principal structural component biological nanowires.
Download or read book Opportunities in Biotechnology for Future Army Applications written by National Research Council and published by National Academies Press. This book was released on 2001-07-11 with total page 118 pages. Available in PDF, EPUB and Kindle. Book excerpt: This report surveys opportunities for future Army applications in biotechnology, including sensors, electronics and computers, materials, logistics, and medical therapeutics, by matching commercial trends and developments with enduring Army requirements. Several biotechnology areas are identified as important for the Army to exploit, either by direct funding of research or by indirect influence of commercial sources, to achieve significant gains in combat effectiveness before 2025.
Download or read book Living Matter written by Rachel Rivenc and published by Getty Conservation Institute. This book was released on 2022-06-13 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: This innovative volume is the first to address the conservation of contemporary art incorporating biological materials such as plants, foods, bodily fluids, or genetically engineered organisms. Eggshells, flowers, onion peels, sponge cake, dried bread, breast milk, bacteria, living organisms—these are just a few of the biological materials that contemporary artists are using to make art. But how can works made from such perishable ingredients be preserved? And what logistical, ethical, and conceptual dilemmas might be posed by doing so? Because they are prone to rapid decay, even complete disappearance, biological materials used in art pose a range of unique conservation challenges. This groundbreaking book probes the issues associated with displaying, collecting, and preserving these unique works of art. The twenty-four papers from the conference present a range of case studies, prominently featuring artists’ perspectives, as well as conceptual discussions, thereby affording a comprehensive and richly detailed overview of current thinking and practices on this topic. Living Matter is the first publication to explore broadly the role of biological materials in the creative process and present a variety of possible approaches to their preservation. The free online edition of this open-access publication is available at www.getty.edu/publications/living-matter/ and includes videos and zoomable illustrations. Also available are free PDF, EPUB, and Kindle/MOBI downloads of the book.
Download or read book Engineering of Biomaterials written by Venina dos Santos and published by Springer. This book was released on 2017-05-31 with total page 92 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book focuses on biomaterials of different forms used for medical implants. The authors introduce the characteristics and properties of biomaterials and then dedicate special chapters to metallic, ceramic, polymeric and composite biomaterials. Case studies on sterilization methods by biomaterials are also presented. Finally, the authors describe the degradation and effects of biomaterials in living tissue.
Download or read book New Frontiers and Applications of Synthetic Biology written by Vijai Singh and published by Academic Press. This book was released on 2022-01-12 with total page 487 pages. Available in PDF, EPUB and Kindle. Book excerpt: New Frontiers and Applications of Synthetic Biology presents a collection of chapters from eminent synthetic biologists across the globe who have established experience and expertise working with synthetic biology. This book offers several important areas of synthetic biology which allow us to read and understand easily. It covers the introduction of synthetic biology and design of promoter, new DNA synthesis and sequencing technology, genome assembly, minimal cells, small synthetic RNA, directed evolution, protein engineering, computational tools, de novo synthesis, phage engineering, a sensor for microorganisms, next-generation diagnostic tools, CRISPR-Cas systems, and more. This book is a good source for not only researchers in designing synthetic biology, but also for researchers, students, synthetic biologists, metabolic engineers, genome engineers, clinicians, industrialists, stakeholders and policymakers interested in harnessing the potential of synthetic biology in many areas. Offers basic understanding and knowledge in several aspects of synthetic biology Covers state-of-the-art tools and technologies of synthetic biology, including promoter design, DNA synthesis, DNA sequencing, genome design, directed evolution, protein engineering, computational tools, phage design, CRISPR-Cas systems, and more Discusses the applications of synthetic biology for smart drugs, vaccines, therapeutics, drug discovery, self-assembled materials, cell free systems, microfluidics, and more
