Download or read book Encyclopedia of Drug Metabolism and Interactions Clinical Aspects written by and published by Wiley. This book was released on 2012-07-03 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: The ideal place to begin researching any question involving drug metabolism and interactions The Encyclopedia of Drug Metabolism and Interactions provides essential support during all phases of drug development, from drug design to drug action and interaction within the human body. This six-volume work covers both preclinical and clinical aspects of drug metabolism and interactions. It also provides a wealth of toxicological, regulatory, and marketing information, all written and edited by leading international experts in the field. By collecting and reviewing the current literature in the field in one expertly organized work, this encyclopedia is the ideal place to begin researching any question involving drug metabolism and interactions. Readers will find such important topics and working tools as: Inhibited or induced enzymes and their impact on drug toxicity and altered response in both animal and human models Effects of both genetic and non-genetic factors on drug metabolism Relationships between a drug metabolism, its activation or inactivation, and a drug's potential toxicity/safety Examples demonstrating all aspects of drug metabolism and interactions in silico, in vitro, in laboratory animals, and in humans Methods and protocols enabling readers to perform seamless studies of metabolism and drug interactions All articles are based on recent findings and standards of practice. By reviewing and contextualizing the current literature, the authors offer new perspectives on our current state of knowledge as well as future directions for research in drug metabolism and interactions. References at the end of each article serve as a gateway to the literature. The Encyclopedia of Drug Metabolism and Interactions is recommended for researchers, physicians, and students at all levels. It introduces the basics to novices and explores the latest science and applications for more experienced investigators.
Download or read book Encyclopedia of Drug Metabolism and Interactions 6 Volume Set written by and published by Wiley. This book was released on 2012-11-05 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: “This one-stop reference brings together information scattered throughout the literature, and it involved the efforts of 270 expert authors from 16 countries — a global endeavor accomplished under the leadership of editor Alexander Lyubimov.” –Book News Inc., February 2013 The Encyclopedia of Drug Metabolism and Interactions provides essential support during all phases of drug development, from drug design to drug action and interaction in patients. This multivolume work covers both preclinical and clinical aspects of drug metabolism and interactions. It also provides a wealth of toxicological, regulatory, and marketing information, all written by leading international experts in the field. Using this reference you’ll discover: • Enzymes that can be inhibited or induced and their impact on drug toxicity and altered response in both animal and human models • Effect of genetic differences and non-genetic factors on drug metabolism • Balance among drug metabolism, its inactivation/activation, and its potential toxicity • Examples demonstrating all aspects of drug metabolism and interactions in silico, in laboratory animals, and in humans • Methods and detailed protocols enabling you to perform seamless studies of metabolism and drug interactions This reference is essential for researchers interested in all aspects of drug development, and chemists, pharmacologists, pharmaceutical specialists, toxicologists, molecular toxicologists, and clinicians, including practitioners and physicians. Enjoy the Online Advantage... The Encyclopedia of Drug Metabolism and Interactions is available online now. For further information visit wileyonlinelibrary.com/ref/lyubimov
Download or read book Encyclopedia of Drug Metabolism and Interactions written by Alexander Lyubimov and published by Anchor Books. This book was released on 2012 with total page 631 pages. Available in PDF, EPUB and Kindle. Book excerpt: This multi-volume, state-of-the-art encyclopedia discusses all preclinical, clinical, toxicological, regulatory and marketing perspectives of drug metabolism and interactions. Methods and detailed protocols describing how to perform studies of metabolism and drug interactions are presented in one of the volumes. All aspects of drug metabolism and interactions in silico, in laboratory animals and in humans, are backed with a range of examples. This reference is essential for researchers interested in all aspects of drug development, and chemists, pharmacologists, pharmaceutical specialists, toxicologists, molecular toxicologists, and clinicians including practitioners and physicians.
Download or read book Encyclopedia of Drug Metabolism and Interactions Clinical Aspects written by and published by Wiley. This book was released on 2012-07-03 with total page 836 pages. Available in PDF, EPUB and Kindle. Book excerpt: "This multi-volume encyclopedia discusses all preclinical, clinical, toxicological, regulatory and marketing perspectives of drug metabolism and interactions. The various types of enzymes that can be inhibited or induced and their impact on drug toxicity and altered response are covered both for animal models and humans"--Provided by publisher.
Download or read book Encyclopedia of Drug Metabolism and Interactions 6 Volume Set written by and published by Wiley. This book was released on 2012-11-05 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: “This one-stop reference brings together information scattered throughout the literature, and it involved the efforts of 270 expert authors from 16 countries — a global endeavor accomplished under the leadership of editor Alexander Lyubimov.” –Book News Inc., February 2013 The Encyclopedia of Drug Metabolism and Interactions provides essential support during all phases of drug development, from drug design to drug action and interaction in patients. This multivolume work covers both preclinical and clinical aspects of drug metabolism and interactions. It also provides a wealth of toxicological, regulatory, and marketing information, all written by leading international experts in the field. Using this reference you’ll discover: • Enzymes that can be inhibited or induced and their impact on drug toxicity and altered response in both animal and human models • Effect of genetic differences and non-genetic factors on drug metabolism • Balance among drug metabolism, its inactivation/activation, and its potential toxicity • Examples demonstrating all aspects of drug metabolism and interactions in silico, in laboratory animals, and in humans • Methods and detailed protocols enabling you to perform seamless studies of metabolism and drug interactions This reference is essential for researchers interested in all aspects of drug development, and chemists, pharmacologists, pharmaceutical specialists, toxicologists, molecular toxicologists, and clinicians, including practitioners and physicians. Enjoy the Online Advantage... The Encyclopedia of Drug Metabolism and Interactions is available online now. For further information visit wileyonlinelibrary.com/ref/lyubimov
Download or read book Encyclopedia of Drug Metabolism and Interactions 6 Volume Set written by and published by Wiley. This book was released on 2012-11-05 with total page 4736 pages. Available in PDF, EPUB and Kindle. Book excerpt: “This one-stop reference brings together information scattered throughout the literature, and it involved the efforts of 270 expert authors from 16 countries — a global endeavor accomplished under the leadership of editor Alexander Lyubimov.” –Book News Inc., February 2013 The Encyclopedia of Drug Metabolism and Interactions provides essential support during all phases of drug development, from drug design to drug action and interaction in patients. This multivolume work covers both preclinical and clinical aspects of drug metabolism and interactions. It also provides a wealth of toxicological, regulatory, and marketing information, all written by leading international experts in the field. Using this reference you’ll discover: • Enzymes that can be inhibited or induced and their impact on drug toxicity and altered response in both animal and human models • Effect of genetic differences and non-genetic factors on drug metabolism • Balance among drug metabolism, its inactivation/activation, and its potential toxicity • Examples demonstrating all aspects of drug metabolism and interactions in silico, in laboratory animals, and in humans • Methods and detailed protocols enabling you to perform seamless studies of metabolism and drug interactions This reference is essential for researchers interested in all aspects of drug development, and chemists, pharmacologists, pharmaceutical specialists, toxicologists, molecular toxicologists, and clinicians, including practitioners and physicians. Enjoy the Online Advantage... The Encyclopedia of Drug Metabolism and Interactions is available online now. For further information visit wileyonlinelibrary.com/ref/lyubimov
Download or read book Encyclopedia of Drug Metabolism and Interactions 6 Volume Set written by and published by Wiley. This book was released on 2012-11-05 with total page 4736 pages. Available in PDF, EPUB and Kindle. Book excerpt: “This one-stop reference brings together information scattered throughout the literature, and it involved the efforts of 270 expert authors from 16 countries — a global endeavor accomplished under the leadership of editor Alexander Lyubimov.” –Book News Inc., February 2013 The Encyclopedia of Drug Metabolism and Interactions provides essential support during all phases of drug development, from drug design to drug action and interaction in patients. This multivolume work covers both preclinical and clinical aspects of drug metabolism and interactions. It also provides a wealth of toxicological, regulatory, and marketing information, all written by leading international experts in the field. Using this reference you’ll discover: • Enzymes that can be inhibited or induced and their impact on drug toxicity and altered response in both animal and human models • Effect of genetic differences and non-genetic factors on drug metabolism • Balance among drug metabolism, its inactivation/activation, and its potential toxicity • Examples demonstrating all aspects of drug metabolism and interactions in silico, in laboratory animals, and in humans • Methods and detailed protocols enabling you to perform seamless studies of metabolism and drug interactions This reference is essential for researchers interested in all aspects of drug development, and chemists, pharmacologists, pharmaceutical specialists, toxicologists, molecular toxicologists, and clinicians, including practitioners and physicians. Enjoy the Online Advantage... The Encyclopedia of Drug Metabolism and Interactions is available online now. For further information visit wileyonlinelibrary.com/ref/lyubimov
Download or read book Drug Metabolism and Pharmacokinetics Quick Guide written by Siamak Cyrus Khojasteh and published by Springer Science & Business Media. This book was released on 2011-04-07 with total page 222 pages. Available in PDF, EPUB and Kindle. Book excerpt: Drug Metabolism and Pharmacokinetics Quick Guide covers a number of aspects of drug assessment at drug discovery and development stages, topics such as pharmacokinetics, absorption, metabolism, enzyme kinetics, drug transporters, drug interactions, drug-like properties, assays and in silico calculations. It covers key concepts, with useful tables on physiological parameters (eg. blood flow to organs in x-species, expression and localization of enzymes and transporters), chemical structure, nomenclature, and moieties leading to bioactivation (with examples). Overall it includes a number of key topics useful at the drug discovery stage, which would serve as a quick reference with several examples from the literature to illustrate the concept.
Download or read book Drug Metabolism written by Bernard Testa and published by . This book was released on 1976 with total page 500 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Drug Repurposing written by Farid A. Badria and published by BoD – Books on Demand. This book was released on 2020-12-02 with total page 236 pages. Available in PDF, EPUB and Kindle. Book excerpt: Drug repurposing or drug repositioning is a new approach to presenting new indications for common commercial and clinically approved existing drugs. For example, chloroquine, an old antimalarial drug, showed promising results for treating COVID-19, interfering with MDR in several types of cancer, and chemosensitizing human leukemic cells.This book focuses on the hypothesis, risk/benefits, and economic impacts of drug repurposing on drug discovery in dermatology, infectious diseases, neurological disorders, cancer, and orphan diseases. It brings together up-to-date research to provide readers with an informative, illustrative, and easy-to-read book useful for students, clinicians, and the pharmaceutical industry.
Download or read book Translational ADMET for Drug Therapy written by Souzan B. Yanni and published by John Wiley & Sons. This book was released on 2015-10-12 with total page 354 pages. Available in PDF, EPUB and Kindle. Book excerpt: Serving as a practical handbook about ADMET for drug therapy, this book presents effective technologies, methods, applications, data interpretation, and decision-making tactics for pharmaceutical and preclinical scientists. Chapters cover case studies and in vivo, in vitro, and computational tools for drug discovery and development, with new translational approaches to clinical drug investigations in various human populations. Illustrates ADME properties, from bedside to bench and bench to bedside, for the design of safe and effective medicine in human populations Provides examples that demonstrate the integration of in vitro, in vivo, and in silico data to address human PKPD and TKTD and help determine the proper therapeutic dosage Presents successful tools for evaluating drugs and covers current translational ADMET with regulatory guidelines Offers a hands-on manual for researchers and scientists to design and execute in vitro, in silico, preclinical, and clinical studies Includes discussion of IND / NDA filing and drug labeling to support drug registration and approval
Download or read book Side Effects of Drugs Annual written by and published by Elsevier. This book was released on 2016-10-25 with total page 604 pages. Available in PDF, EPUB and Kindle. Book excerpt: Side Effects of Drugs Annual: A Worldwide Yearly Survey of New Data in Adverse Drug Reactions was first published in 1977, and has been continually published as a yearly update to the voluminous encyclopedia Meyler's Side Effects of Drugs. Each annual provides clinicians and medical investigators with a reliable and critical survey of new data and trends in the area of adverse drug reactions and interactions, with an international team of specialists contributing their expertise each year. Provides a critical yearly survey of the new data and trends regarding the side effects of drugs Authored and reviewed by worldwide pioneers in the clinical and practice sciences Presents an essential clinical on the side effects of drugs for practitioners and healthcare professionals alike
Download or read book Encyclopedia of Forensic and Legal Medicine written by and published by Academic Press. This book was released on 2015-09-29 with total page 3080 pages. Available in PDF, EPUB and Kindle. Book excerpt: Encyclopedia of Forensic and Legal Medicine, Volumes 1-4, Second Edition is a pioneering four volume encyclopedia compiled by an international team of forensic specialists who explore the relationship between law, medicine, and science in the study of forensics. This important work includes over three hundred state-of-the-art chapters, with articles covering crime-solving techniques such as autopsies, ballistics, fingerprinting, hair and fiber analysis, and the sophisticated procedures associated with terrorism investigations, forensic chemistry, DNA, and immunoassays. Available online, and in four printed volumes, the encyclopedia is an essential reference for any practitioner in a forensic, medical, healthcare, legal, judicial, or investigative field looking for easily accessible and authoritative overviews on a wide range of topics. Chapters have been arranged in alphabetical order, and are written in a clear-and-concise manner, with definitions provided in the case of obscure terms and information supplemented with pictures, tables, and diagrams. Each topic includes cross-referencing to related articles and case studies where further explanation is required, along with references to external sources for further reading. Brings together all appropriate aspects of forensic medicine and legal medicine Contains color figures, sample forms, and other materials that the reader can adapt for their own practice Also available in an on-line version which provides numerous additional reference and research tools, additional multimedia, and powerful search functions Each topic includes cross-referencing to related articles and case studies where further explanation is required, along with references to external sources for further reading
Download or read book Pharmacokinetics and Pharmacodynamics of Biotech Drugs written by Bernd Meibohm and published by John Wiley & Sons. This book was released on 2006-12-13 with total page 426 pages. Available in PDF, EPUB and Kindle. Book excerpt: This first ever coverage of the pharmacokinetic and pharmacodynamic characteristics of biopharmaceuticals meets the need for a comprehensive book in this field. It spans all topics from lead identification right up to final-stage clinical trials. Following an introduction to the role of PK and PD in the development of biotech drugs, the book goes on to cover the basics, including the pharmacokinetics of peptides, monoclonal antibodies, antisense oligonucleotides, as well as viral and non-viral gene delivery vectors. The second section discusses such challenges and opportunities as pulmonary delivery of proteins and peptides, and the delivery of oligonucleotides. The final section considers the integration of PK and PD concepts into the biotech drug development plan, taking as case studies the preclinical and clinical drug development of tasidotin, as well as the examples of cetuximab and pegfilgrastim. The result is vital reading for all pharmaceutical researchers.
Download or read book Liver Pathophysiology written by Pablo Muriel and published by Academic Press. This book was released on 2017-03-02 with total page 914 pages. Available in PDF, EPUB and Kindle. Book excerpt: Liver Pathophysiology: Therapies and Antioxidants is a complete volume on morphology, physiology, biochemistry, molecular biology and treatment of liver diseases. It uses an integral approach towards the role of free radicals in the pathogenesis of hepatic injury, and how their deleterious effects may be abrogated by the use of antioxidants. Written by the most prominent authors in the field, this book will be of use to basic and clinical scientists and clinicians working in the biological sciences, especially those dedicated to the study and treatment of liver pathologies. Presents the most recent advances in hepatology, with a special focus on the role of oxidative stress in liver injury. Provides in vivo and in vitro models to study human liver pathology. Explains the beneficial effects of antioxidants on liver diseases. Contains the most recent and modern treatments of hepatic pathologies, including, but not limited to, stem cells repopulation, gene therapy and liver transplantation.
Download or read book Encyclopedia of Human Nutrition written by Lindsay Allen and published by Elsevier. This book was released on 2005-07-20 with total page 2388 pages. Available in PDF, EPUB and Kindle. Book excerpt: Encyclopedia of Human Nutrition, Second Edition is a thorough revision and 20% expansion of the 1998 release, reflecting the continuing scientific advances in the field of human nutrition. Now a four-volume set, nearly 300 articles with concise, up-to-date information are complemented by an award-winning indexing system. Included is expanded coverage of epidemiology of diet-related diseases, functional foods, food safety, clinical nutrition and gastrointestinal disorders. Virtually everyone will find the Encyclopedia of Human Nutrition an easy-to-use resource making it an ideal reference choice for both the professional and the non-professional alike. Also available online via ScienceDirect – featuring extensive browsing, searching, and internal cross-referencing between articles in the work, plus dynamic linking to journal articles and abstract databases, making navigation flexible and easy. For more information, pricing options and availability visit www.info.sciencedirect.com. FEATURES OF SECOND PRINT EDITION Now a four-volume set with over 250 articles Expanded coverage of epidemiology of diet-related diseases, functional foods, food safety, and gastrointestinal disorders, among other topics ONLINE FEATURES AND FUNCTIONALITIES Browse the whole work by volume, authors or article titles Full and extensive subject index can be searched or browsed online, and takes you directly to the indexed paragraph, section, figure or table Basic and advanced search functionality across the entire work or by specific volume Users can build, save and re-run seraches, as well as combine saved searches Extensive internal cross-referencing and dynamic linking from biliographic references to primary-source material, increasing the scope of your research rapidly and effectively All articles available as full-text HTML files, or as PDF files that can be viewed, downloaded or printed in their original format
Download or read book Encyclopedia of the Neurological Sciences written by and published by Academic Press. This book was released on 2014-04-29 with total page 4744 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Encyclopedia of the Neurological Sciences, Second Edition, Four Volume Set develops from the first edition, covering all areas of neurological sciences through over 1000 entries focused on a wide variety of topics in neurology, neurosurgery, psychiatry and other related areas of neuroscience. The contributing authors represent all aspects of neurology from many viewpoints and disciplines to provide a complete overview of the field. Entries are designed to be understandable without detailed background knowledge in the subject matter, and cross-referencing and suggested further reading lead the reader from a basic knowledge of the subject to more advanced understanding. The easy-to-use 'encyclopedic-dictionary' format of the Encyclopedia of the Neurological Sciences, Second Edition features alphabetic entries, extensive cross-referencing, and a thorough index for quick reference. The wealth of information provided by these four volumes makes this reference work a trusted source of valuable information for a wide range of researchers, from undergraduate students to academic researchers. Provides comprehensive coverage of the field of neurological science in over 1,000 entries in 4 volumes "Encyclopedic-dictionary" format provides for concise, readable entries and easy searching Presents complete, up-to-date information on 32 separate areas of neurology Entries are supplemented with extensive cross-referencing, useful references to primary research articles, and an extensive index
