Download or read book Principles of Pharmaceutical Chemistry written by Mathew George and published by MV Learning. This book was released on 2015-08-30 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Systematically draws together the huge amount of information available in this field for the benefit of students. The authors have taken great care to discuss every topic with clarity and simplicity. With its methodical presentation of complicated chemical reactions, this text will help students grasp the subject easily and quickly.

Download or read book Color Atlas of Biochemistry written by Jan Koolman and published by Thieme. This book was released on 2011-01-01 with total page 482 pages. Available in PDF, EPUB and Kindle. Book excerpt: Totally revised and expanded, the Color Atlas of Biochemistry presents the fundamentals of human and mammalian biochemistry on 215 stunning color plates.Alongside a short introduction to chemistry and the classical topics of biochemistry, the 2nd edition covers new approaches and aspects in biochemistry, such as links between chemical structure and biological function or pathways for information transfer, as well as recent developments and discoveries, such as the structures of many new important molecules. Key features of this title include:- The unique combination of highly effective color graphics and comprehensive figure legends;- Unified color-coding of atoms, coenzymes, chemical classes, and cell organelles that allows quick recognition of all involved systems;- Computer graphics provide simulated 3D representation of many important molecules.This Flexibook is ideal for students of medicine and biochemistry and a valuable source of reference for practitioners.

Download or read book Diversity Oriented Synthesis written by Andrea Trabocchi and published by John Wiley & Sons. This book was released on 2013-06-17 with total page 550 pages. Available in PDF, EPUB and Kindle. Book excerpt: Discover an enhanced synthetic approach to developing and screening chemical compound libraries Diversity-oriented synthesis is a new paradigm for developing large collections of structurally diverse small molecules as probes to investigate biological pathways. This book presents the most effective methods in diversity-oriented synthesis for creating small molecule collections. It offers tested and proven strategies for developing diversity-oriented synthetic libraries and screening methods for identifying ligands. Lastly, it explores some promising new applications based on diversity-oriented synthesis that have the potential to dramatically advance studies in drug discovery and chemical biology. Diversity-Oriented Synthesis begins with an introductory chapter that explores the basics, including a discussion of the relationship between diversity-oriented synthesis and classic combinatorial chemistry. Divided into four parts, the book: Offers key chemical methods for the generation of small molecules using diversity-oriented principles, including peptidomimetics and macrocycles Expands on the concept of diversity-oriented synthesis by describing chemical libraries Provides modern approaches to screening diversity-oriented synthetic libraries, including high-throughput and high-content screening, small molecule microarrays, and smart screening assays Presents the applications of diversity-oriented synthetic libraries and small molecules in drug discovery and chemical biology, reporting the results of key studies and forecasting the role of diversity-oriented synthesis in future biomedical research This book has been written and edited by leading international experts in organic synthesis and its applications. Their contributions are based on a thorough review of the current literature as well as their own firsthand experience developing synthetic methods and applications. Clearly written and extensively referenced, Diversity-Oriented Synthesis introduces novices to this highly promising field of research and serves as a springboard for experts to advance their own research studies and develop new applications.

Download or read book Peptidomimetics in Organic and Medicinal Chemistry written by Antonio Guarna and published by John Wiley & Sons. This book was released on 2014-04-07 with total page 334 pages. Available in PDF, EPUB and Kindle. Book excerpt: A peptidomimetic is a small protein-like chain designed to mimic a peptide with adjusted molecular properties such as enhanced stability or biological activity. It is a very powerful approach for the generation of small-molecule-based drugs as enzyme inhibitors or receptor ligands. Peptidomimetics in Organic and Medicinal Chemistry outlines the concepts and synthetic strategies underlying the building of bioactive compounds of a peptidomimetic nature. Topics covered include the chemistry of unnatural amino acids, peptide- and scaffold-based peptidomimetics, amino acid-side chain isosteres, backbone isosteres, dipeptide isosteres, beta-turn peptidomimetics, proline-mimetics as turn inducers, cyclic scaffolds, amino acid surrogates, and scaffolds for combinatorial chemistry of peptidomimetics. Case studies in the hit-to-lead process, such as the development of integrin ligands and thrombin inhibitors, illustrate the successful application of peptidomimetics in drug discovery.

Download or read book Small Molecule Drug Discovery written by Andrea Trabocchi and published by Elsevier. This book was released on 2019-11-23 with total page 358 pages. Available in PDF, EPUB and Kindle. Book excerpt: Small Molecule Drug Discovery: Methods, Molecules and Applications presents the methods used to identify bioactive small molecules, synthetic strategies and techniques to produce novel chemical entities and small molecule libraries, chemoinformatics to characterize and enumerate chemical libraries, and screening methods, including biophysical techniques, virtual screening and phenotypic screening. The second part of the book gives an overview of privileged cyclic small molecules and major classes of natural product-derived small molecules, including carbohydrate-derived compounds, peptides and peptidomimetics, and alkaloid-inspired compounds. The last section comprises an exciting collection of selected case studies on drug discovery enabled by small molecules in the fields of cancer research, CNS diseases and infectious diseases. The discovery of novel molecular entities capable of specific interactions represents a significant challenge in early drug discovery. Small molecules are low molecular weight organic compounds that include natural products and metabolites, as well as drugs and other xenobiotics. When the biological target is well defined and understood, the rational design of small molecule ligands is possible. Alternatively, small molecule libraries are being used for unbiased assays for complex diseases where a target is unknown or multiple factors contribute to a disease pathology. - Outlines modern concepts and synthetic strategies underlying the building of small molecules and their chemical libraries useful for drug discovery - Provides modern biophysical methods to screening small molecule libraries, including high-throughput screening, small molecule microarrays, phenotypic screening and chemical genetics - Presents the most advanced chemoinformatics tools to characterize the structural features of small molecule libraries in terms of chemical diversity and complexity, also including the application of virtual screening approaches - Gives an overview of structural features and classification of natural product-derived small molecules, including carbohydrate derivatives, peptides and peptidomimetics, and alkaloid-inspired small molecules

Download or read book Chemical Age written by and published by . This book was released on 1910 with total page 210 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Carrion Ecology Evolution and Their Applications written by M. Eric Benbow and published by CRC Press. This book was released on 2015-08-18 with total page 596 pages. Available in PDF, EPUB and Kindle. Book excerpt: Shortlisted for the 2018 TWS Wildlife Publication Awards in the edited book categoryDecomposition and recycling of vertebrate remains have been understudied, hampered largely due to these processes being aesthetically challenging (e.g., smell and sight). Technological innovations have provided the means to explore new and historically understo

Download or read book Principles of Fluorescence Spectroscopy written by Joseph R. Lakowicz and published by Springer Science & Business Media. This book was released on 2007-12-05 with total page 961 pages. Available in PDF, EPUB and Kindle. Book excerpt: The third edition of this established classic text reference builds upon the strengths of its very popular predecessors. Organized as a broadly useful textbook Principles of Fluorescence Spectroscopy, 3rd edition maintains its emphasis on basics, while updating the examples to include recent results from the scientific literature. The third edition includes new chapters on single molecule detection, fluorescence correlation spectroscopy, novel probes and radiative decay engineering. Includes a link to Springer Extras to download files reproducing all book artwork, for easy use in lecture slides. This is an essential volume for students, researchers, and industry professionals in biophysics, biochemistry, biotechnology, bioengineering, biology and medicine.

Download or read book Five a Day for Better Health written by and published by . This book was released on 1994 with total page 690 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Organometallic Polymers written by Charles E. Jr. Carraher and published by Elsevier. This book was released on 2012-12-02 with total page 368 pages. Available in PDF, EPUB and Kindle. Book excerpt: Organometallic Polymers focuses on the synthesis, characterization, and potential applications of organometallic polymers. The discussion is organized around seven themes: vinyl polymerization of organometallic monomers; condensation polymerization of organometallic monomers; polymer-bound catalysts; applications of organotin polymers; developments in organosilicon polymers; phosphonitrile and sulfur nitride polymers; and coordination polymers. This book is comprised of 33 chapters and begins with a general review of polymerized vinyl monomers containing transition metals, as well as the reactivity of such monomers in addition to homo- and copolymerizations. The following chapters explore the participation of the ferrocene nucleus in the polymerization of vinylferrocene and its effect on polymer properties; thermomechanical transitions of ferrocene-containing polymers; photocrosslinkable organometallic polyesters; and supported catalysts for ethylene polymerization. The remaining sections discuss antifouling applications of various tin-containing organometallic polymers; structure and applications of polyphosphazenes and polymeric sulfur nitride; and coordination of inorganic ions to polymers. This monograph will be a useful resource for organic chemists and research workers in the field.

Download or read book How does MRI work written by Dominik Weishaupt and published by Springer Science & Business Media. This book was released on 2008-02-01 with total page 172 pages. Available in PDF, EPUB and Kindle. Book excerpt: A succinct introduction to the physics and function of magnetic resonance imaging with an emphasis on practical information. This thoroughly revised second edition is clearly structured. The underlying physical principles of the MR experiment are described and the basic pulse sequences commonly used in clinical MRI. It progresses to more advanced techniques such as parallel imaging and cardiovascular MR imaging. An extensive glossary offers rapid access to MRI terminology and will help those seeking to understand this interesting fascinating subject.

Download or read book A History of Western Architecture written by David Watkin and published by . This book was released on 1996 with total page 612 pages. Available in PDF, EPUB and Kindle. Book excerpt: Preface p. 6 1 Mesopotamia and Egypt p. 9 Mesopotamia p. 9 Egypt p. 13 2 The Classical Foundation: Greek, Hellenistic, Roman p. 19 The Bronze Age Heritage p. 19 The Hellenistic Background p. 41 The Rise of Rome p. 57 3 Early Christian and Byzantine p. 89 4 Carolingian and Romanesque p. 107 5 The Gothic Experiment p. 149 France p. 150 England p. 168 Germany and Central Europe, Belgium, Italy, Spain, Portugal p. 185 Town Planning p. 207 6 Renaissance Harmony p. 211 The Birth of the Renaissance p. 211 High Renaissance p. 223 The Renaissance Outside Italy p. 251 Town Planning p. 279 7 Baroque Expansion p. 283 Italy p. 283 Baroque Outside Italy p. 314 Town Planning p. 362 8 Eighteenth-Century Classicism p. 369 The Impact of Rome p. 369 The Rise of Neo-Classicism in France p. 391 The Classical Tradition Elsewhere in Europe p. 410 The Rise of Classicism in the USA p. 424 Town Planning p. 434 9 The Nineteenth Century p. 439 France p. 439 Britain p. 459 Germany, Austria and Italy p. 477 Scandinavia, Russia and Greece p. 497 Belgium and Holland p. 509 USA p. 512 Town Planning p. 530 10 Art Nouveau p. 537 Belgium and France p. 537 Scotland and England p. 543 Germany, Austria and Italy p. 546 Spain p. 556 11 The Twentieth Century p. 565 USA Up to 1939 p. 565 Europe Up to 1939 p. 582 Modernism After 1945 p. 648 Post-Modernism p. 660 Town Planning p. 668 Architecture for the Millennium p. 670 Glossary p. 685 Further Reading p. 688 Acknowledgements p. 693 Index p. 694.

Download or read book Electron Microscopy written by John J. Bozzola and published by Jones & Bartlett Learning. This book was released on 1999 with total page 702 pages. Available in PDF, EPUB and Kindle. Book excerpt: New edition of an introductory reference that covers all of the important aspects of electron microscopy from a biological perspective, including theory of scanning and transmission; specimen preparation; darkroom, digital imaging, and image analysis; laboratory safety; interpretation of images; and an atlas of ultrastructure. Generously illustrated with bandw line drawings and photographs. Annotation copyrighted by Book News, Inc., Portland, OR

Download or read book Chemical Metallurgical Engineering written by Eugene Franz Roeber and published by . This book was released on 1918 with total page 858 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Organic Chemical Transformations written by and published by . This book was released on 1923 with total page 8 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book The Formation of Chinese Civilization written by Kwang-chih Chang and published by Yale University Press. This book was released on 2005-01-01 with total page 396 pages. Available in PDF, EPUB and Kindle. Book excerpt: Paleolithic sites from one million years ago, Neolithic sites with extraordinary jade and ceramic artifacts, excavated tombs and palaces of the Shang and Zhou dynasties--all these are part of the archaeological riches of China. This magnificent book surveys China's archaeological remains and in the process rewrites the early history of the world's most enduring civilization. Eminent scholars from China and America show how archaeological evidence establishes that Chinese culture did not spread from a single central area, as was long assumed, but emerged out of geographically diverse, interacting Neolithic cultures. Taking us to the great archaeological finds of the past hundred years--tombs, temples, palaces, cities--they shed new light on many aspects of Chinese life. With a wealth of fascinating detail and hundreds of reproductions of archaeological discoveries, including very recent ones, this book is an invaluable resource for anyone interested in Chinese antiquity and Chinese views on the formation of their own civilization.

Download or read book Biocatalysis written by W.-D. Fessner and published by Springer Science & Business Media. This book was released on 2003-09-05 with total page 273 pages. Available in PDF, EPUB and Kindle. Book excerpt: Here, leading contributors from the forefront of this exciting technology present authoritative and timely reviews on the state of the art of biocatalysis. They cover the whole spectrum from the discovery of novel enzymes - by modern screening, evolutionary or immunological approaches - through immobilization techniques for technical processes, to their use in the asymmetric synthesis of important target compounds.