Download or read book Effects Of Nicotine Withdrawal On Motivation Reward Sensitivity And Reward Learning written by Jason A. Oliver and published by . This book was released on 2015 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt: Research on addictive behavior has traditionally emphasized the role that primary reinforcing effects of drugs of abuse plays in the development and maintenance of dependence. However, contemporary behavioral economic theory and animal models of nicotine dependence suggest the need for greater attention to the impact that response to alternative rewards may have on smoking behavior. The present study sought to investigate the impact of nicotine withdrawal on self-report, behavioral and neural indices of motivation, immediate response to rewards and the capacity to learn and modify behavior in response to positive and negative feedback. Heavy smokers (n = 48) completed two laboratory sessions following overnight deprivation, during which they smoked either nicotinized or denicotinized cigarettes. At each session, they completed a reward prediction and feedback learning task while electro-encephalographic recordings were obtained, as well as resting state recordings which were used to extract global indices of motivational state. Results confirmed that nicotine withdrawal produced an avoidant motivational state. This effect was strongly related to numerous indices of smoking motivation. Exploratory analyses also revealed numerous moderators of these effects. Behavioral data from tasks provided some support for the impact of nicotine withdrawal on reward and feedback processing, though minimal impact was observed for neural indices. Together, results confirm the manifestation of a broad-spanning impact of nicotine withdrawal on motivational state, but effects on specific reward systems remains unknown. Future research should examine the impact of nicotine withdrawal on other reward-related constructs to better delineate these effects.

Download or read book The Motivational Impact of Nicotine and its Role in Tobacco Use written by Rick A. Bevins and published by Springer Science & Business Media. This book was released on 2008-12-15 with total page 213 pages. Available in PDF, EPUB and Kindle. Book excerpt: More and more scientists are applying the concepts of motivation and related constructs to modify the behavior of drug-addicted and dependent people. Here, authors discuss effective ‘translational’ strategies for decreasing and preventing tobacco use.

Download or read book Negative Affective States and Cognitive Impairments in Nicotine Dependence written by F. Scott Hall and published by Academic Press. This book was released on 2016-08-17 with total page 364 pages. Available in PDF, EPUB and Kindle. Book excerpt: Negative Affective States and Cognitive Impairments in Nicotine Dependence is the only book of its kind that addresses nicotine use and abuse in the context of negative reinforcement mechanisms. Written and edited by leading investigators in addiction, affective, genetic, and cognitive research, it provides researchers and advanced students with an overview of the clinical bases of these effects, allowing them to fully understand the various underlying dysfunctions that drive nicotine use in different individuals. In addition, this book examines animal models that researchers have utilized to investigate the biological bases of these dysfunctions. The combination of clinical and preclinical approaches to understanding nicotine dependence makes this book an invaluable resource for researchers and practitioners seeking to develop targeted treatments aimed at ameliorating symptoms of nicotine dependence, as well as identifying premorbid differences in affective or cognitive function. - Provides a unique perspective on nicotine dependence that emphasizes negative reinforcement rather than positive reinforcement - Examines psychiatric comorbidities and alleviation of withdrawal states as motivation for continued tobacco use - Includes both clinical and preclinical perspectives - Includes genetic and multi-neurotransmitter perspectives on nicotine use and withdrawal - Emphasizes heterogeneity of underlying reasons for smoking, the need for multiple animal models to understand this heterogeneity, and the expectation of heterogeneous responses to potential treatments, underscoring the need for personalized therapeutics

Download or read book Reward Motivation as a Mechanism Linking Personality and Intermittent Smoking written by Robert MacLean and published by . This book was released on 2015 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt: The negative public health impact of daily smoking has been well established over decades of empirical research. As such, traditional conceptualizations of nicotine addiction emphasize behaviors typically experienced by daily smokers such as withdrawal avoidance. Nondaily/intermittent smokers (ITS), a rising population with similar negative health consequences as daily smokers, have received comparatively little attention. Most notably, nondaily smokers exhibit comparable rates of cessation failure and number of quit attempts as daily smokers. Since nondaily smokers do not smoke on a regular basis, withdrawal avoidance is not likely to motivate smoking maintenance and cessation failure. Instead, nondaily smokers may be motivated by "peak seeking" or the acute rewarding effects of nicotine. Individual factors associated with sensitivity to rewarding stimuli can provide insight into potential mechanisms by which peak seeking motivates smoking behavior. The current study used a rewarded antisaccade task followed by a 7-day ecological momentary assessment period to evaluate the relationship between disinhibition traits, reward motivation, and momentary factors related to reward seeking and the subjective effects of nicotine. More specifically, the analysis tested the hypothesis that reward motivation mediates the relationship between disinhibition and momentary behavior. Results failed to support a mediational model; however, the results highlighted potentially important factors related to smoking behavior in ITS. Primary results suggest that ITS with greater disinhibition and reward motivation report higher momentary adventurousness after smoking a cigarette, but not during nonsmoking occasions. Therefore, within nondaily smokers, consideration of alternative factors that motivate smoking behavior may help better conceptualize problematic smoking in this population. Additionally, relationships between personality, reward motivation, and momentary responses highlight the potential importance of studying co-occurring negative health behaviors in developing intervention strategies.

Download or read book How Tobacco Smoke Causes Disease written by United States. Public Health Service. Office of the Surgeon General and published by . This book was released on 2010 with total page 728 pages. Available in PDF, EPUB and Kindle. Book excerpt: This report considers the biological and behavioral mechanisms that may underlie the pathogenicity of tobacco smoke. Many Surgeon General's reports have considered research findings on mechanisms in assessing the biological plausibility of associations observed in epidemiologic studies. Mechanisms of disease are important because they may provide plausibility, which is one of the guideline criteria for assessing evidence on causation. This report specifically reviews the evidence on the potential mechanisms by which smoking causes diseases and considers whether a mechanism is likely to be operative in the production of human disease by tobacco smoke. This evidence is relevant to understanding how smoking causes disease, to identifying those who may be particularly susceptible, and to assessing the potential risks of tobacco products.

Download or read book The Neuropharmacology of Nicotine Dependence written by David J.K. Balfour and published by Springer. This book was released on 2015-01-31 with total page 177 pages. Available in PDF, EPUB and Kindle. Book excerpt: The primary purpose of this book and its companion volume The Behavioral Genetics of Nicotine and Tobacco is to explore the ways in which recent studies on nicotine and its role in tobacco addiction have opened our eyes to the psychopharmacological properties of this unique and fascinating drug. While The Behavioral Genetics of Nicotine and Tobacco considers the molecular and genetic factors which influence behavioral responses to nicotine and how these may impact on the role of nicotine in tobacco dependence, the present book focuses on the complex neural and psychological mechanisms that mediate nicotine dependence in experimental animal models and their relationship to tobacco addiction in humans. These volumes will provide readers a contemporary overview of current research on nicotine psychopharmacology and its role in tobacco dependence from leaders in this field of researchand will hopefully prove valuable to those who are developing their own research programmes in this important topic.

Download or read book Encyclopedia of Psychopharmacology written by Ian Stolerman and published by Springer Science & Business Media. This book was released on 2010-07-31 with total page 1433 pages. Available in PDF, EPUB and Kindle. Book excerpt: Here is a broad overview of the central topics and issues in psychopharmacology, biological psychiatry and behavioral neurosciences, with information about developments in the field, including novel drugs and technologies. The more than 2000 entries are written by leading experts in pharmacology and psychiatry and comprise in-depth essays, illustrated with full-color figures, and are presented in a lucid style.

Download or read book Methods of Behavior Analysis in Neuroscience written by Jerry J. Buccafusco and published by CRC Press. This book was released on 2000-08-29 with total page 341 pages. Available in PDF, EPUB and Kindle. Book excerpt: Using the most well-studied behavioral analyses of animal subjects to promote a better understanding of the effects of disease and the effects of new therapeutic treatments on human cognition, Methods of Behavior Analysis in Neuroscience provides a reference manual for molecular and cellular research scientists in both academia and the pharmaceutic

Download or read book The Cambridge Handbook of Motivation and Learning written by K. Ann Renninger and published by Cambridge University Press. This book was released on 2019-02-14 with total page 1172 pages. Available in PDF, EPUB and Kindle. Book excerpt: Written by leading researchers in educational and social psychology, learning science, and neuroscience, this edited volume is suitable for a wide-academic readership. It gives definitions of key terms related to motivation and learning alongside developed explanations of significant findings in the field. It also presents cohesive descriptions concerning how motivation relates to learning, and produces a novel and insightful combination of issues and findings from studies of motivation and/or learning across the authors' collective range of scientific fields. The authors provide a variety of perspectives on motivational constructs and their measurement, which can be used by multiple and distinct scientific communities, both basic and applied.

Download or read book The Interdisciplinary Science of Consumption written by Stephanie D. Preston and published by MIT Press. This book was released on 2014-08 with total page 343 pages. Available in PDF, EPUB and Kindle. Book excerpt: Scholars from psychology, neuroscience, economics, animal behavior, and evolution describe the latest research on the causes and consequences of overconsumption. Our drive to consume—our desire for food, clothing, smart phones, and megahomes—evolved from our ancestors' drive to survive. But the psychological and neural processes that originally evolved to guide mammals toward resources that are necessary but scarce may mislead us in modern conditions of material abundance. Such phenomena as obesity, financial bubbles, hoarding, and shopping sprees suggest a mismatch between our instinct to consume and our current environment. This volume brings together research from psychology, neuroscience, economics, marketing, animal behavior, and evolution to explore the causes and consequences of consumption. Contributors consider such topics as how animal food-storing informs human consumption; the downside of evolved “fast and frugal” rules for eating; how future discounting and the draw toward immediate rewards influence food consumption, addiction, and our ability to save; overconsumption as social display; and the policy implications of consumption science. Taken together, the chapters make the case for an emerging interdisciplinary science of consumption that reflects commonalities across species, domains, and fields of inquiry. By carefully comparing mechanisms that underlie seemingly disparate outcomes, we can achieve a unified understanding of consumption that could benefit both science and society.

Download or read book The Cambridge Handbook of Substance and Behavioral Addictions written by Steve Sussman and published by Cambridge University Press. This book was released on 2020-08-06 with total page 1413 pages. Available in PDF, EPUB and Kindle. Book excerpt: Written by leaders in the addictions field, 100 authors from six countries, this handbook is a thoroughly comprehensive resource. Philosophical and legal issues are addressed, while conceptual underpinnings are provided through explanations of appetitive motivation, incentive sensitization, reward deficiency, and behavioral economics theories. Major clinical and research methods are clearly mapped out (e.g. MRI, behavioral economics, interview assessments, and qualitative approaches), outlining their strengths and weaknesses, giving the reader the tools needed to guide their research and practice aims. The etiology of addiction at various levels of analysis is discussed, including neurobiology, cognition, groups, culture, and environment, which simultaneously lays out the foundations and high-level discourse to serve both novice and expert researchers and clinicians. Importantly, the volume explores the prevention and treatment of such addictions as alcohol, tobacco, novel drugs, food, gambling, sex, work, shopping, the internet, and several seldom-investigated behaviors (e.g. love, tanning, or exercise).

Download or read book Treating Tobacco Use and Dependence 2008 Update Clinical Practice Guideline written by and published by DIANE Publishing. This book was released on 2009 with total page 276 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Mindfulness oriented Recovery Enhancement for Addiction Stress and Pain written by Eric L. Garland and published by NASW Press. This book was released on 2013 with total page 206 pages. Available in PDF, EPUB and Kindle. Book excerpt: "Human existence can be beset by a variety of negative mental states such that life seems devoid of meaning, but it can also be liberated--a meaningful life reclaimed and savored through cultivation of a higher kind of mind. This quality, mindfulness, refers to both a set of contemplative practices and certain distinct psychological states and traits, and it can be cultivated through intentional effort and training. In Mindfulness-Oriented Recovery Enhancement for Addiction, Stress, and Pain, Eric L. Garland presents an innovative program of intervention that can be put into practice by therapists working with people struggling with addiction and the conditions that underlie it. Unlike other substance abuse treatment modalities, which focus largely on relapse prevention, Mindfulness-Oriented Recovery Enhancement (MORE) concentrates on helping people to recover a sense of meaning and fulfillment in everyday life, embracing its pleasures and pain without avoiding challenges by turning to substance use. Along with chapters on the bipsychosocial model underlying MORE and the current state of research on mindfulness, this book includes a complete treatment manual laying out for clinicians, step by step, how to run MORE groups--including adaptations to address chronic pain and prescription opioid misuse-- and enhance the holistic recovery process for people striving to overcome addiction. With addiction a widespread and growing problem in our society, Mindfulness-Oriented Recovery Enhancement could not be more timely or needed. It integrates the latest research on addiction, cognitive neuroscience, positive psychology, and mindfulness into a practice that has garnered empirical support and holds the promise of release and fulfillment for those who suffer from addiction."--Publisher's website.

Download or read book Addiction Neuroethics written by Adrian Carter and published by Academic Press. This book was released on 2011-10-04 with total page 347 pages. Available in PDF, EPUB and Kindle. Book excerpt: Research increasingly suggests that addiction has a genetic and neurobiological basis, but efforts to translate research into effective clinical treatments and social policy needs to be informed by careful ethical analyses of the personal and social implications. Scientists and policy makers alike must consider possible unintended negative consequences of neuroscience research so that the promise of reducing the burden and incidence of addiction can be fully realized and new advances translated into clinically meaningful and effective treatments. This volume brings together leading addiction researchers and practitioners with neuroethicists and social scientists to specifically discuss the ethical, philosophical, legal and social implications of neuroscience research of addiction, as well as its translation into effective, economical and appropriate policy and treatments. Chapters explore the history of ideas about addiction, the neuroscience of drug use and addiction, prevention and treatment of addiction, the moral implications of addiction neuroscience, legal issues and human rights, research ethics, and public policy. - Features outstanding and truly international scholarship, with chapters written by leading experts in neuroscience, addiction medicine, psychology and more - Informs psychologists of related research in neuroscience and vice versa, giving researchers easy one-stop access to knowledge outside their area of specialty

Download or read book Neural Mechanisms of Addiction written by Mary Torregrossa and published by Academic Press. This book was released on 2018-08-24 with total page 308 pages. Available in PDF, EPUB and Kindle. Book excerpt: Neural Mechanisms of Addiction is the only book available that synthesizes the latest research in the field into a single, accessible resource covering all aspects of how addiction develops and persists in the brain. The book summarizes our most recent understanding on the neural mechanisms underlying addiction. It also examines numerous biobehavioral aspects of addiction disorders, such as reinforcement learning, reward, cognitive dysfunction, stress, and sleep and circadian rhythms that are not covered in any other publication. Readers with find the most up-to-date information on which to build a foundation for their future research in this expanding field. Combining chapters from leading researchers and thought leaders, this book is an indispensable guide for students and investigators engaged in addiction research. - Transcends multiple neural, neurochemical and behavioral domains - Summarizes advances in the field of addiction research since the advent of optogenetics - Discusses the most current, leading theories of addiction, including molecular mechanisms and dopamine mechanisms

Download or read book Neurocircuitry of Addiction written by Nicholas W. Gilpin and published by Academic Press. This book was released on 2022-11-29 with total page 560 pages. Available in PDF, EPUB and Kindle. Book excerpt: People use drugs for many different reasons, including the pursuit of "high," social factors and self-medication of other conditions. Many millions of people are addicted to at least one substance, and the cost of addiction is immense, at both the individual and societal levels. Neurocircuitry of Addiction is the first book of its kind, with a focus on addiction neuroscience from a neural circuit perspective. This book begins with a primer on circuit-based neuroscience that equips the reader with an understanding of the applications described throughout the book. Each subsequent chapter positions a different brain region at the "center" of addiction neurocircuitry and goes on to describe the anatomical connectivity of that brain region, how those circuits are affected by drug exposure, and the role of those circuits in controlling addiction-related behaviors. All chapters of this book are written by content experts for a target audience that has some basic neuroscience background, but no prior in-depth knowledge regarding the neurocircuitry of addiction. Reviews the circuit-based tools that are used by scientists to investigate neural circuit function Describes how acute and chronic alcohol and drug exposure affect neural circuit function Describes the state of the science regarding the role of specific neural circuis in drug addiction Chapters include data from both human neuroscience and animal models

Download or read book Handbook of Neuroethics written by Jens Clausen and published by Springer. This book was released on 2014-10-28 with total page 1850 pages. Available in PDF, EPUB and Kindle. Book excerpt: Based on the study of neuroscientific developments and innovations, examined from different angles, this Handbook provides a comprehensive overview of the international neuroethical debate, and offers unprecedented insights into the impact of neuroscientific research, diagnosis, and therapy. Neuroethics – as a multi-disciplinary and inter-disciplinary endeavor – examines the implications of the neurosciences for human beings in general and for their self-understanding and their social interactions in particular. The range of approaches adopted in neuroethics and thus in this handbook includes but is not limited to historical, anthropological, ethical, philosophical, theological, sociological and legal approaches. The Handbook deals with a plethora of topics, divided into in three parts: the first part contains discussions of theories of neuroethics and how neuroscience impacts on our understanding of personal identity, free will, and other philosophical concepts. The second part is dedicated to issues involved in current and future clinical applications of neurosciences, such as brain stimulation, brain imaging, prosthetics, addiction, and psychiatric ethics. The final part deals with neuroethics and society and includes chapters on neurolaw, neurotheology, neuromarketing, and enhancement.