Download or read book Dynamics of Cell and Tissue Motion written by Wolfgang Alt and published by Birkhäuser. This book was released on 2012-12-06 with total page 336 pages. Available in PDF, EPUB and Kindle. Book excerpt: An interdisciplinary study explaining the dynamics underlying biological motion – one of the most obvious expressions of self-organization. Designed for a broad audience from bioscientists to applied mathematicians, this book considers possible synergetic mechanisms of interaction and cooperation on different microscopic levels.
Download or read book Dynamics of Cell and Tissue Motion written by Wolfgang Alt and published by . This book was released on 1997-01-01 with total page 336 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Molecular Biology of the Cell written by and published by . This book was released on 2002 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Cell and Matrix Mechanics written by Roland Kaunas and published by CRC Press. This book was released on 2014-10-23 with total page 370 pages. Available in PDF, EPUB and Kindle. Book excerpt: Explores a Range of Multiscale Biomechanics/Mechanobiology ConceptsCell and Matrix Mechanics presents cutting-edge research at the molecular, cellular, and tissue levels in the field of cell mechanics. This book involves key experts in the field, and covers crucial areas of cell and tissue mechanics, with an emphasis on the roles of mechanical forc
Download or read book Mechanics of Growing Tissues written by Jonas Ranft and published by . This book was released on 2012 with total page 162 pages. Available in PDF, EPUB and Kindle. Book excerpt: In this thesis, we investigate the collective organization of cells by cell division and cell death. The multicellular dynamics of growing tissues is influenced by mechanical conditions and can give rise to cell movements. We develop a continuum description of tissue dynamics, which describes the stress distribution and the cell flow field on large scales. Cell division and apoptosis introduce stress sources that, in general, are anisotropic. We show that the tissue effectively behaves as a viscoelastic fluid with a relaxation time set by the rates of division and apoptosis. If the tissue is confined in a fixed volume, it reaches a state in which division and apoptosis balance. In this state, cells undergo a diffusive motion driven by the stochasticity of division and apoptosis. We calculate the diffusion coefficient and compare our results concerning both diffusion and viscosity to simulations of multicellular systems. Introducing a second material component that accounts for the extracellular fluid, we show that a finite permeability of the tissue gives rise to additional mechanical effects. In the limit of long times, the mechanical response of the tissue to external perturbations is confined to a region of which the size depends on the ratio of tissue viscosity and cell-fluid friction. Last but not least, we study the propagation of an interface between two different cell populations within a tissue. We distinguish two different modes of propagation of the more proliferative population: a diffusive regime in which relative fluxes dominate the expansion, and a propulsive regime in which the proliferation gives rise to dominating convective flows.
Download or read book Cell Movement written by Magdalena Stolarska and published by Springer. This book was released on 2018-11-22 with total page 312 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book contains a collection of original research articles and review articles that describe novel mathematical modeling techniques and the application of those techniques to models of cell motility in a variety of contexts. The aim is to highlight some of the recent mathematical work geared at understanding the coordination of intracellular processes involved in the movement of cells. This collection will benefit researchers interested in cell motility as well graduate students taking a topics course in this area.
Download or read book Single Cell Based Models in Biology and Medicine written by Alexander Anderson and published by Springer Science & Business Media. This book was released on 2007-08-08 with total page 346 pages. Available in PDF, EPUB and Kindle. Book excerpt: Aimed at postgraduate students in a variety of biology-related disciplines, this volume presents a collection of mathematical and computational single-cell-based models and their application. The main sections cover four general model groupings: hybrid cellular automata, cellular potts, lattice-free cells, and viscoelastic cells. Each section is introduced by a discussion of the applicability of the particular modelling approach and its advantages and disadvantages, which will make the book suitable for students starting research in mathematical biology as well as scientists modelling multicellular processes.
Download or read book Biomat 2005 Proceedings Of The International Symposium On Mathematical And Computational Biology written by Rubem P Mondaini and published by World Scientific. This book was released on 2006-04-25 with total page 409 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume contains the contributions of the keynote speakers to the BIOMAT 2005 symposium, as well as a collection of selected papers by pioneering researchers. It provides a comprehensive review of the mathematical modeling of cancer development, Alzheimer's disease, malaria, and aneurysm development. Various models for the immune system and epidemiological issues are analyzed and reviewed. The book also explores protein structure prediction by optimization and combinatorial techniques (Steiner trees). The coverage includes bioinformatics issues, regulation of gene expression, evolution, development, DNA and array modeling, and small world networks.
Download or read book The Fluid Dynamics of Cell Motility written by Eric Lauga and published by Cambridge University Press. This book was released on 2020-11-05 with total page 392 pages. Available in PDF, EPUB and Kindle. Book excerpt: Fluid dynamics plays a crucial role in many cellular processes, including the locomotion of cells such as bacteria and spermatozoa. These organisms possess flagella, slender organelles whose time periodic motion in a fluid environment gives rise to motility. Sitting at the intersection of applied mathematics, physics and biology, the fluid dynamics of cell motility is one of the most successful applications of mathematical tools to the understanding of the biological world. Based on courses taught over several years, it details the mathematical modelling necessary to understand cell motility in fluids, covering phenomena ranging from single-cell motion to instabilities in cell populations. Each chapter introduces mathematical models to rationalise experiments, uses physical intuition to interpret mathematical results, highlights the history of the field and discusses notable current research questions. All mathematical derivations are included for students new to the field, and end-of-chapter exercises help consolidate understanding and practise applying the concepts.
Download or read book The Guide to Investigation of Mouse Pregnancy written by B. Anne Croy and published by Academic Press. This book was released on 2013-12-09 with total page 829 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Guide to Investigation of Mouse Pregnancy is the first publication to cover the mouse placenta or the angiogenic tree the mother develops to support the placenta. This much-needed resource covers monitoring of the cardiovascular system, gestational programming of chronic adult disease, epigenetic regulation, gene imprinting, and stem cells. Offering detailed and integrated information on how drugs, biologics, stress, and manipulations impact pregnancy in the mouse model, this reference highlights techniques used to analyze mouse pregnancy. Joining the ranks of much referenced mouse resources, The Guide to Investigation of Mouse Pregnancy is the only manual providing needed content on pregnancy in animal models for translational medicine and research. - Provides instruction on how to collect pre-clinical data on pregnancy in mouse models for eventual use in human applications - Describes the angiogenic tree the mother's uterus develops to support pregnancy and the monitoring of pregnancy-induced cardiovascular changes - Educates readers on placental cell lineages, decidual development including immune cells, epigenetic regulation, gene imprinting, stem cells, birth and lactation - Discusses how stress, environmental toxicants and other manipulations impact upon placental function and pregnancy success
Download or read book The Dynamic Body Tissues written by W. S. Bullough and published by . This book was released on 1983-06-30 with total page 192 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Advanced Diffusion Encoding Methods in MRI written by Daniel Topgaard and published by Royal Society of Chemistry. This book was released on 2020-08-17 with total page 455 pages. Available in PDF, EPUB and Kindle. Book excerpt: The medical MRI community is by far the largest user of diffusion NMR techniques and this book captures the current surge of methods and provides a primary source to aid adoption in this field. There is a trend to adapting the more advanced diffusion encoding sequences developed by NMR researchers within the fields of porous media, chemical engineering, and colloid science to medical research. Recently published papers indicate great potential for improved diagnosis of the numerous pathological conditions associated with changes of tissue microstructure that are invisible to conventional diffusion MRI. This book disseminates these recent developments to the wider community of MRI researchers and clinicians. The chapters cover the theoretical basis, hardware and pulse sequences, data analysis and validation, and recent applications aimed at promoting further growth in the field. This is a fast moving field and chapters are written by key MRI scientists that have contributed to the successful translation of the advanced diffusion NMR methods to the context of medical MRI, from global locations.
Download or read book Physical Models of Cell Motility written by Igor S. Aranson and published by Springer. This book was released on 2015-12-16 with total page 208 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book surveys the most recent advances in physics-inspired cell movement models. This synergetic, cross-disciplinary effort to increase the fidelity of computational algorithms will lead to a better understanding of the complex biomechanics of cell movement, and stimulate progress in research on related active matter systems, from suspensions of bacteria and synthetic swimmers to cell tissues and cytoskeleton.Cell motility and collective motion are among the most important themes in biology and statistical physics of out-of-equilibrium systems, and crucial for morphogenesis, wound healing, and immune response in eukaryotic organisms. It is also relevant for the development of effective treatment strategies for diseases such as cancer, and for the design of bioactive surfaces for cell sorting and manipulation. Substrate-based cell motility is, however, a very complex process as regulatory pathways and physical force generation mechanisms are intertwined. To understand the interplay between adhesion, force generation and motility, an abundance of computational models have been proposed in recent years, from finite element to immerse interface methods and phase field approaches.This book is primarily written for physicists, mathematical biologists and biomedical engineers working in this rapidly expanding field, and can serve as supplementary reading for advanced graduate courses in biophysics and mathematical biology. The e-book incorporates experimental and computer animations illustrating various aspects of cell movement./div
Download or read book Nonlinear Physics of Complex Systems written by Jürgen Parisi and published by Springer. This book was released on 1996-10-04 with total page 412 pages. Available in PDF, EPUB and Kindle. Book excerpt: The review articles in this book treat the overall nonlinear and complex behavior of nature from the viewpoint of such diverse research fields as fluid mechanics, condensed matter physics, biophysics, biochemistry, biology, and applied mathematics. Attention is focussed on a broad and comprehensive overview of recent developments and perspectives. Particular attention is given to the so-far unsolved problem of how to capture the mutual interplay between the microscopic and macroscopic dynamics that extend over various length and time scales. The book addresses researchers as well as graduate students.
Download or read book Cardiovascular Soft Tissue Mechanics written by Stephen C. Cowin and published by Springer Science & Business Media. This book was released on 2001 with total page 252 pages. Available in PDF, EPUB and Kindle. Book excerpt: Cowin (New York Center for Biomedical Engineering) and Humphrey (biomedical engineering, Texas A&M U.) present seven papers that discuss current research and future directions. Topics concern tissues within the cardiovascular system (arteries, the heart, and biaxial testing of planar tissues such as heart valves). Themes include an emphasis on data on the underlying microstructure, especially collagen; the consideration of the fact that both arteries and the heart contain muscle and that there is, therefore, a need to quantify both the active and passive response; constitutive relations for active behavior; and the growth and remodeling of cardiovascular tissues. Of interest to cardiovascular and biomechanics soft tissue researchers, and bioengineers. Annotation copyrighted by Book News, Inc., Portland, OR.
Download or read book Precision Medicine in Chronic Inflammation written by and published by Frontiers Media SA. This book was released on 2021-11-09 with total page 159 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Capillary Fluid Exchange written by Joshua Scallan and published by Morgan & Claypool Publishers. This book was released on 2010 with total page 86 pages. Available in PDF, EPUB and Kindle. Book excerpt: The partition of fluid between the vascular and interstitial compartments is regulated by forces (hydrostatic and oncotic) operating across the microvascular walls and the surface areas of permeable structures comprising the endothelial barrier to fluid and solute exchange, as well as within the extracellular matrix and lymphatics. In addition to its role in the regulation of vascular volume, transcapillary fluid filtration also allows for continuous turnover of water bathing tissue cells, providing the medium for diffusional flux of oxygen and nutrients required for cellular metabolism and removal of metabolic byproducts. Transendothelial volume flow has also been shown to influence vascular smooth muscle tone in arterioles, hydraulic conductivity in capillaries, and neutrophil transmigration across postcapillary venules, while the flow of this filtrate through the interstitial spaces functions to modify the activities of parenchymal, resident tissue, and metastasizing tumor cells. Likewise, the flow of lymph, which is driven by capillary filtration, is important for the transport of immune and tumor cells, antigen delivery to lymph nodes, and for return of filtered fluid and extravasated proteins to the blood. Given this background, the aims of this treatise are to summarize our current understanding of the factors involved in the regulation of transcapillary fluid movement, how fluid movements across the endothelial barrier and through the interstitium and lymphatic vessels influence cell function and behavior, and the pathophysiology of edema formation. Table of Contents: Fluid Movement Across the Endothelial Barrier / The Interstitium / The Lymphatic Vasculature / Pathophysiology of Edema Formation
