Download or read book Drying of a Single Suspension Droplet in Suspension Plasma Spray written by Seyyed Morteza Javid and published by . This book was released on 2021 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Suspension plasma spray is a powerful coating technique for depositing high-quality thermal barrier coatings with promising mechanical and physical properties while taking advantage of the well-established atmospheric plasma spray process. In this process, fine ceramic particles are suspended in liquids such as water or ethanol before injection into a plasma jet. The heat from plasma evaporates the carrier liquid of injected suspension droplets and leads to an agglomeration of the particles. The agglomeration process plays a crucial role in the state of particles before impacting a substrate and, consequently, the mechanical properties of the coating. In this work, numerical models for simulating different cases of drying of a single suspension droplet in processes with a high evaporation rate like suspension plasma spray are devised. The models use a Lagrangian method for tracking suspended solid particles and the Eulerian method for the liquid phase. These models not only demonstrate droplet distortion during evaporation but also predict solid particles behavior suspended in the droplet. The numerical models can describe consecutive states of the agglomeration process, including droplet shrinkage, particle accumulation on droplet surface, and buckling. Also, the numerical analysis sheds more light on the complex phenomena of buckling, especially the interaction of the droplet interface and suspended solid particles, and different types of suspension droplet buckling. The numerical results reveal that the role of capillary forces in the shape of agglomerated particles is significant. It is found that particle-induced surface pressure drives the buckling of the suspension droplet. It is also shown that the particle-induced surface pressure reaches a threshold value at the onset of buckling and overcomes surface tension. Finally, the models have been validated by comparing the simulation results with designed experiments. The numerical results are in good agreement with the experimental ones, both qualitatively and quantitatively.

Download or read book Temporal and Spatial Study of Drying of Suspension and Solution Droplets for Tablets Coating Purposes written by Silvana Sartori Velasco and published by . This book was released on 2010 with total page 122 pages. Available in PDF, EPUB and Kindle. Book excerpt: Suspensions or solutions of polymers are widely used in the pharmaceutical industry to coat tablets with different agents. These allow controlling the rate at which the drug is delivered, taste or appearance. The coating is performed by spraying and drying the tablets at moderate temperatures. The spreading of the coating on the pills surface depends on the droplet Webber and Reynolds numbers, angle of impact, but especially on the rheological properties of the drop. We present simplified models for the evaporation of suspension and solution droplets in a hot air environment with temperatures substantially lower than the boiling temperature of the carrier fluid. As the liquid vaporizes from the surface in the solution case, the solution becomes more concentrated, until reaching its saturation point. After saturation, precipitation occurs uniformly within the drop. As the surface regresses, a compacting front formed by the solid precipitate at its maximum packing density advances into the drop, while more solute continues.

Download or read book Thermal Spray Fundamentals written by Pierre L. Fauchais and published by Springer Science & Business Media. This book was released on 2014-01-24 with total page 1587 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book provides readers with the fundamentals necessary for understanding thermal spray technology. Coverage includes in-depth discussions of various thermal spray processes, feedstock materials, particle-jet interactions, and associated yet very critical topics: diagnostics, current and emerging applications, surface science, and pre and post-treatment. This book will serve as an invaluable resource as a textbook for graduate courses in the field and as an exhaustive reference for professionals involved in thermal spray technology.

Download or read book Frontiers in Spray Drying written by Nan Fu and published by CRC Press. This book was released on 2020-08-13 with total page 95 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book covers the latest developments and advances in spray drying and describes how they impact the basic aspect of designing and operating spray dryers. This generic approach allows users to understand how different basic aspects of spray drying have advanced. Users will learn how to apply these advances in their own specific spray drying applications. This book also discusses the handling and control of spray dried products. Includes the latest techniques for use in the design and operation of spray drying operations Covers the basic operations of spray drying that can be applied to different applications of spray drying Discusses the handling and control of spray dried product qualities from a general approach, allowing readers to tailor these approaches to their own specific products This book is aimed at professionals, researchers, and academics working in the fields of food, chemical, pharmaceutical, and industrial engineering.

Download or read book Handbook of Food Powders written by Bhesh Bhandari and published by Elsevier. This book was released on 2023-11-11 with total page 598 pages. Available in PDF, EPUB and Kindle. Book excerpt: Handbook of Food Powders: Chemistry and Technology, Second Edition covers current developments in food powder technology, such as Microbial decontamination of food powders, Gas and oil encapsulated powders, and Plant-based protein powders among other important topics. Sections introduce processing and handling technologies for food powders, focus on powder properties, including surface composition, rehydration and techniques to analyze the particle size of food powders, and highlight specialty food powders such as dairy powders, fruit and vegetable powders and coating foods with powders. Edited by a team of international experts in the field, this book continues to be the only quality reference on food powder technology available for the audiences of professionals in the food powder production and handling industries. It is also ideal for development and quality control professionals in the food industry who use powders in foods, and for researchers, scientists and academics interested in the field. - Introduces six new chapters that incorporate the current developments in food powder technology - Examines powder properties, including surface composition, shelf life and techniques used to examine particle size - Focuses on specialty powders such as dairy, infant formulas, powdered egg, fruit and vegetable, and culinary and specialty products

Download or read book Thermal Barrier Coatings written by and published by Elsevier. This book was released on 2011-01-14 with total page 358 pages. Available in PDF, EPUB and Kindle. Book excerpt: Effective coatings are essential to counteract the effects of corrosion and degradation of exposed materials in high-temperature environments such as gas turbine engines. Thermal barrier coatings reviews the latest advances in processing and performance of thermal barrier coatings, as well as their failure mechanisms. Part one reviews the materials and structures of thermal barrier coatings. Chapters cover both metallic and ceramic coating materials as well as nanostructured coatings. Part two covers established and advanced processing and spraying techniques, with chapters on the latest advances in plasma spraying and plasma vapour deposition as well as detonation gun spraying. Part three discusses the performance and failure of thermal barrier coatings, including oxidation and hot-corrosion, non-destructive evaluation and new materials, technologies and processes. With its distinguished editors and international team of contributors, Thermal barrier coatings is an essential reference for professional engineers in such industries as energy production, aerospace and chemical engineering as well as academic researchers in materials. Reviews the latest advances in processing and performance of thermal barrier coatings, as well as their failure mechanisms Explores the materials and structures of thermal barrier coatings incorporating cover both metallic and ceramic coating materials as well as nanostructured coating Assesses established and advanced processing and spraying techniques, including plasma vapour deposition and detonation gun spraying

Download or read book Handbook of Thermal Plasmas written by Maher I. Boulos and published by Springer Nature. This book was released on 2023-02-20 with total page 1973 pages. Available in PDF, EPUB and Kindle. Book excerpt: This authoritative reference presents a comprehensive review of the evolution of plasma science and technology fundamentals over the past five decades. One of this field’s principal challenges has been its multidisciplinary nature requiring coverage of fundamental plasma physics in plasma generation, transport phenomena under high-temperature conditions, involving momentum, heat and mass transfer, and high-temperature reaction kinetics, as well as fundamentals of material science under extreme conditions. The book is structured in five distinct parts, which are presented in a reader-friendly format allowing for detailed coverage of the science base and engineering aspects of the technology including plasma generation, mathematical modeling, diagnostics, and industrial applications of thermal plasma technology. This book is an essential resource for practicing engineers, research scientists, and graduate students working in the field.

Download or read book Pharmaceutical Engineering English Edition written by Dr. M. Senthil Kumar and published by Thakur Publication Private Limited. This book was released on 2021-03-11 with total page 264 pages. Available in PDF, EPUB and Kindle. Book excerpt: Buy E-Book of Pharmaceutical Engineering (English Edition) Book For B. Pharm 3rd Semester of U.P. State Universities

Download or read book Drying of Complex Fluid Drops written by David Brutin and published by Royal Society of Chemistry. This book was released on 2022-06-01 with total page 244 pages. Available in PDF, EPUB and Kindle. Book excerpt: Coffee rings, paint drying, blood splatter are all examples of complex fluids drying. Understanding the phenomena of complex fluid drops with respect to drying is important for technology and a lot of research in academia and industry is poured into this topic. This book addresses this industrially important area and provides a thorough grounding to the field. Addressing the fundamental underpinnings of wetting, spreading and drying, the book then takes the reader through key applications grouped into themes, including colloidal droplets (used in printing) and biological (e.g. bloodstain analysis for forensics). With a section on modelling and simulation to balance experiment with computational tools, this book will appeal to anyone working in complex fluids across classical fluid mechanics, soft matter, and chemical, biological and mechanical engineering

Download or read book Droplet Wetting and Evaporation written by David Brutin and published by Academic Press. This book was released on 2015-05-11 with total page 464 pages. Available in PDF, EPUB and Kindle. Book excerpt: Droplet Wetting and Evaporation provides engineers, students, and researchers with the first comprehensive guide to the theory and applications of droplet wetting and evaporation. Beginning with a relevant theoretical background, the book moves on to consider specific aspects, including heat transfer, flow instabilities, and the drying of complex fluid droplets. Each chapter covers the principles of the subject, addressing corresponding practical issues and problems. The text is ideal for a broad range of domains, from aerospace and materials, to biomedical applications, comprehensively relaying the challenges and approaches from the different communities leading the way in droplet research and development. - Provides a broad, cross-subject coverage of theory and application that is ideal for engineers, students and researchers who need to follow all major developments in this interdisciplinary field - Includes comprehensive discussions of heat transfer, flow instabilities, and the drying of complex fluid droplets - Begins with an accessible summary of fundamental theory before moving on to specific areas such as heat transfer, flow instabilities, and the drying of complex fluid droplets

Download or read book Handbook of Atomization and Sprays written by Nasser Ashgriz and published by Springer Science & Business Media. This book was released on 2011-02-18 with total page 922 pages. Available in PDF, EPUB and Kindle. Book excerpt: Atomization and sprays are used in a wide range of industries: mechanical, chemical, aerospace, and civil engineering; material science and metallurgy; food; pharmaceutical, forestry, environmental protection; medicine; agriculture; meteorology and others. Some specific applications are spray combustion in furnaces, gas turbines and rockets, spray drying and cooling, air conditioning, powdered metallurgy, spray painting and coating, inhalation therapy, and many others. The Handbook of Atomization and Sprays will bring together the fundamental and applied material from all fields into one comprehensive source. Subject areas included in the reference are droplets, theoretical models and numerical simulations, phase Doppler particle analysis, applications, devices and more.

Download or read book Plasma Spray Coating written by Robert B. Heimann and published by John Wiley & Sons. This book was released on 2008-07-11 with total page 354 pages. Available in PDF, EPUB and Kindle. Book excerpt: Over the past two decades, thermal spraying of metallic, ceramic and composite coatings has emerged as a powerful tool for surface engineering, with many new applications and markets continually being developed. This book will help materials scientists and engineers to choose the most appropriate combination of materials, equipment, and operation parameters for the design of high-performance coatings with new functional properties and improved service life. Includes: * a thorough treatment of the fundamental physical processes governing plasma spray technology; * a critical assessment of advantages and disadvantages of the method compared with other suface coating techniques; * a discussion of basic equipment requirements and limitations; * case studies and typical applications to solve industrial problems. Plasma-Spray Coating offers a stimulating combination of basic concepts and practical applications. Materials scientists and engineers, as well as graduate students will find this book of enormous value.

Download or read book Encyclopedia of Meat Sciences written by Carrick Devine and published by Elsevier. This book was released on 2014-07-22 with total page 1697 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Encyclopedia of Meat Sciences, Second Edition, Three Volume Set prepared by an international team of experts, is a reference work that covers all important aspects of meat science from stable to table. Its topics range from muscle physiology, biochemistry (including post mortem biochemistry), and processing procedures to the processes of tenderization and flavor development, various processed meat products, animal production, microbiology and food safety, and carcass composition. It also considers animal welfare, animal genetics, genomics, consumer issues, ethnic meat products, nutrition, the history of each species, cooking procedures, human health and nutrition, and waste management. Fully up-to-date, this important reference work provides an invaluable source of information for both researchers and professional food scientists. It appeals to all those wanting a one-stop guide to the meat sciences. More than 200 articles covering all areas of meat sciences Substantially revised and updated since the previous edition was published in 2004 Full color throughout

Download or read book Drying of Droplets written by Moshe Levy and published by . This book was released on 2010 with total page 152 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Production of Uniform Particles Via Single Stream Drying and New Applications of the Reaction Engineering Approach written by Kamleshkumar Chhanabhai Patel and published by . This book was released on 2008 with total page 540 pages. Available in PDF, EPUB and Kindle. Book excerpt: In this thesis investigations are carried out on two research topics in context to spray drying. The first research topic is the production of dried particles having uniform characteristics. The second research topic is the development of new applications of the reaction engineering approach which, in recent times, has emerged as an effective tool to formulate drying kinetics models. The reaction engineering approach is also implemented to simulate the drying of monodisperse droplets corresponding to the experimental work in the first research topic. Manufacturing micron- and nano-sized particles having uniform characteristics has recently become a popular research area due to the unique functionalities of these kinds of particles in biomedical, drug delivery, functional foods, nutraceuticals, cosmetics and other valuable applications. Spray drying has been a common and economical route to produce dried particles. A typical characteristic of spray dried products is the existence of a significant variation in particle properties such as size and morphology. One possible idea to restrict this product non-uniformity is to achieve a good control over the droplet's behaviour and characteristics inside the drying chamber. The current thesis has investigated an innovative spray drying technique, i.e. a single stream drying approach in order to restrict product non-uniformity. In this drying approach, identical sized droplets having vertical trajectories are dried under controlled gas flow conditions. The piezoelectricity-driven monodisperse droplet generator is used as the atomizer to disperse liquid droplets. A prototype single stream dryer was assembled based on the single stream drying approach using various components designed in the laboratory and several parts purchased from the market. Experiments were carried out using aqueous lactose solutions as a model system in order to check the practicability of manufacturing uniform-sized spherical particles. Preliminary results were found to be positive and reported in this thesis. Mathematical models on the drying of monodisperse droplets were developed in order to predict important droplet and gas parameter profiles during single stream drying. These models serve as a platform for design, optimization and scale-up purposes. Several important advantages and drawbacks of single stream drying are also reported. Problems encountered during the experimental work and future recommendations are presented in detail so that a more robust and effective drying research tool can be developed in future. Recently the reaction engineering approach (REA) has emerged as a simple and reliable technique to characterize the drying of various food and dairy materials. In this thesis two new applications of the REA are described for the first time in context to convective drying of aqueous droplets. The REA is used in this study to formulate the drying kinetics model for the drying of aqueous sucrose and maltodextrin (DE6) droplets. The effect of initial moisture content was explicitly demonstrated. The development of a new 'composite' REA which aimed to model the drying of aqueous droplets containing multiple solutes has been described. The composite REA was found to be suitable to characterize the drying behaviour of aqueous sucrose-maltodextrin mixtures of different proportions. The second new application of the REA is the development of a procedure to estimate surface properties of aqueous droplets during drying. In literature various droplet characteristics such as surface moisture contents were normally estimated using the diffusion-based drying kinetics model or the receding interface model. Surface moisture content and surface glass transition temperature profiles were evaluated here using a lumped-parameter model (REA) during the drying of aqueous sucrose, maltodextrin (DE6) and their mixtures. The same experimental data used for the development of the composite REA were used to yield predictions. The procedure was found to be useful in estimating surface moisture contents and understanding the stickiness behaviour of sugar droplets during drying. During the formulation of the REA-based drying kinetics model in this thesis, the assumption of uniform temperature within droplets was used. In most studies published in literature the uniform temperature assumption was justified by calculating the heat-transfer Biot numbers at the beginning and end of drying. However, the conventional Biot number concept does not take into account the evaporation effect and therefore would not be suitable to drying scenarios. In this thesis, a new approximation procedure is developed to estimate surface-centre temperature differences within materials following the entire drying process. This new procedure was helpful to check the extent of temperature non-uniformity within skim milk droplets under isothermal laboratory conditions as well as industrial spray drying conditions. Both conventional and drying-based Biot numbers are calculated and compared. Predictions showed that temperature gradients within the droplets were negligible during the drying of suspended droplets under laboratory drying conditions (slow drying), whilst the gradients were small and existed only for a short drying period for small droplets under industrial spray drying conditions (fast drying). Furthermore, it was observed that the maximum temperature gradient within the droplets did not exist at the starting or end points of the drying process, and therefore the estimation of Biot numbers at the starting and end point does not reflect temperature non-uniformity under drying conditions. This is a significant theoretical development in the area.

Download or read book Colloids in Drug Delivery written by Monzer Fanun and published by CRC Press. This book was released on 2016-04-19 with total page 652 pages. Available in PDF, EPUB and Kindle. Book excerpt: Colloidal drug delivery systems present a range of therapeutic benefits in the treatment of a number of challenging conditions, allowing researchers to cross barriers that have previously prevented efficient treatment while offering improved and more targeted absorption. Summarizing recent research in the field, Colloids in Drug Delivery assembles

Download or read book Development of Biopharmaceutical Drug Device Products written by Feroz Jameel and published by Springer Nature. This book was released on 2020-03-13 with total page 888 pages. Available in PDF, EPUB and Kindle. Book excerpt: The biotechnology/biopharmaceutical sector has tremendously grown which led to the invention of engineered antibodies such as Antibody Drug Conjugates (ADCs), Bispecific T-cell engager (BITES), Dual Variable Domain (DVD) antibodies, and fusion proteins that are currently being used as therapeutic agents for immunology, oncology and other disease conditions. Regulatory agencies have raised the bar for the development and manufacture of antibody-based products, expecting to see the use of Quality by Design (QbD) elements demonstrating an in-depth understanding of product and process based on sound science. Drug delivery systems have become an increasingly important part of the therapy and most biopharmaceuticals for self-administration are being marketed as combination products. A survey of the market indicates that there is a strong need for a new book that will provide “one stop shopping” for the latest information and knowledge of the scientific and engineering advances made over the last few years in the area of biopharmaceutical product development. The new book entitled Development of Biopharmaceutical Drug Device Products is a reference text for scientists and engineers in the biopharmaceutical industry, academia or regulatory agencies. With insightful chapters from experts in the field, this new book reviews first principles, covers recent technological advancements and provides case studies and regulatory strategies relating to the development and manufacture of antibody-based products. It covers topics such as the importance of early preformulation studies during drug discovery to influence molecular selection for development, formulation strategies for new modalities, and the analytical techniques used to characterize them. It also addresses important considerations for later stage development such as the development of robust formulations and processes, including process engineering and modeling of manufacturing unit operations, the design of analytical comparability studies, and characterization of primary containers (pre-filled syringes and vials).Finally, the latter half of the book reviews key considerations to ensure the development and approval of a patient-centered delivery system design. This involves the evolving regulatory framework with perspectives from both the US and EU industry experts, the role of international standards, design control/risk management, human factors and its importance in the product development and regulatory approval process, as well as review of the risk-based approach to bridging between devices used in clinical trials and the to-be-marketed device. Finally, case studies are provided throughout.The typical readership would have biology and/or engineering degrees and would include researchers, scientific leaders, industry specialists and technology developers working in the biopharmaceutical field.