Download or read book Medications for Opioid Use Disorder Save Lives written by National Academies of Sciences, Engineering, and Medicine and published by National Academies Press. This book was released on 2019-06-16 with total page 175 pages. Available in PDF, EPUB and Kindle. Book excerpt: The opioid crisis in the United States has come about because of excessive use of these drugs for both legal and illicit purposes and unprecedented levels of consequent opioid use disorder (OUD). More than 2 million people in the United States are estimated to have OUD, which is caused by prolonged use of prescription opioids, heroin, or other illicit opioids. OUD is a life-threatening condition associated with a 20-fold greater risk of early death due to overdose, infectious diseases, trauma, and suicide. Mortality related to OUD continues to escalate as this public health crisis gathers momentum across the country, with opioid overdoses killing more than 47,000 people in 2017 in the United States. Efforts to date have made no real headway in stemming this crisis, in large part because tools that already existâ€"like evidence-based medicationsâ€"are not being deployed to maximum impact. To support the dissemination of accurate patient-focused information about treatments for addiction, and to help provide scientific solutions to the current opioid crisis, this report studies the evidence base on medication assisted treatment (MAT) for OUD. It examines available evidence on the range of parameters and circumstances in which MAT can be effectively delivered and identifies additional research needed.

Download or read book Higher and Higher written by Jost Sauer and published by Allen & Unwin. This book was released on 2006-08-01 with total page 239 pages. Available in PDF, EPUB and Kindle. Book excerpt: 'This is one of the most powerful, real, relevant, and thought-provoking books I have picked up in some time.' The Art of Healing Have you ever wondered: Whether marijuana can lead to harder drugs. How come you feel immortal on speed. Why acid trips can feel so good - or so bad. Why total strangers bond on ecstasy. Whether drugs can enhance your spirituality. Why some antidepressants can make your depression worse. Higher and Higher offers a fresh perspective on every aspect of drugs from addiction to repair. Using a new analytical approach that fuses Traditional Chinese Medicine and Energy Medicine, it shows you how to integrate past drug experiences into your life in a positive way. Learn how to reclaim the excitement and exhilaration drugs offer, through a unique mind - body - spirit workout. Combining case studies with a candid account of Jost Sauer's own journey through drugs, depression and near self-destruction, to good health and freedom, Higher and Higher is in turn confronting, thought-provoking and informative. This uplifting and accessible read takes you on a roller-coaster ride from the relentless pursuit of drug-induced highs to genuine wellness. This unique book, based on Jost Sauer's personal and professional experience, provides invaluable insights into the human need to feel good, and details a healthy and sustainable path for you to reach the ultimate high. 'I have to say that you really hit it on the head with this one.' Anthony

Download or read book Improving and Accelerating Therapeutic Development for Nervous System Disorders written by Institute of Medicine and published by National Academies Press. This book was released on 2014-02-06 with total page 107 pages. Available in PDF, EPUB and Kindle. Book excerpt: Improving and Accelerating Therapeutic Development for Nervous System Disorders is the summary of a workshop convened by the IOM Forum on Neuroscience and Nervous System Disorders to examine opportunities to accelerate early phases of drug development for nervous system drug discovery. Workshop participants discussed challenges in neuroscience research for enabling faster entry of potential treatments into first-in-human trials, explored how new and emerging tools and technologies may improve the efficiency of research, and considered mechanisms to facilitate a more effective and efficient development pipeline. There are several challenges to the current drug development pipeline for nervous system disorders. The fundamental etiology and pathophysiology of many nervous system disorders are unknown and the brain is inaccessible to study, making it difficult to develop accurate models. Patient heterogeneity is high, disease pathology can occur years to decades before becoming clinically apparent, and diagnostic and treatment biomarkers are lacking. In addition, the lack of validated targets, limitations related to the predictive validity of animal models - the extent to which the model predicts clinical efficacy - and regulatory barriers can also impede translation and drug development for nervous system disorders. Improving and Accelerating Therapeutic Development for Nervous System Disorders identifies avenues for moving directly from cellular models to human trials, minimizing the need for animal models to test efficacy, and discusses the potential benefits and risks of such an approach. This report is a timely discussion of opportunities to improve early drug development with a focus toward preclinical trials.

Download or read book Leaving Drug and Alcohol Addictions for Good written by Sharon R Montgomery and published by . This book was released on 2020-08-12 with total page 370 pages. Available in PDF, EPUB and Kindle. Book excerpt: "Joe's story is important because it tells how a person or family struggling with addictions can find success working a combination of biochemical repair along with the standard mental/emotional program for addictions." --Dr. Bill Billica DYING FOR PLEASURE IS NO WAY TO LIVE Joe Eisele knows this firsthand. He became addicted to alcohol and drugs as a teenager, and only found the path to recovery by incorporating biochemical restoration into his treatment. In Leaving Drug and Alcohol Addictions for Good, readers experience the frightening ride on what Joe calls "the addiction train." Joe's story is layered with Sharon's, whose son became caught in the devastating, often deadly trajectory of addiction while Joe and Sharon were working on this book. "There is a big difference between finding pleasure in what life brings and and chasing pleasure at any cost," says Joe, the co-founder and clinical director of InnerBalance Health Center in Loveland, Colorado. His treatment center for people with drug and alcohol addictions includes the critical component often missing from other programs: biochemical restoration. Whether you are coping with addiction yourself or trying to help someone else get off the addiction train, you'll find a deep understanding and empathy in Joe's story, and fresh hope in how you truly can leave drug and alcohol addictions for good.

Download or read book Drugs Brains and Behavior written by and published by . This book was released on 2007 with total page 76 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Magnesium in the Central Nervous System written by Robert Vink and published by University of Adelaide Press. This book was released on 2011 with total page 354 pages. Available in PDF, EPUB and Kindle. Book excerpt: The brain is the most complex organ in our body. Indeed, it is perhaps the most complex structure we have ever encountered in nature. Both structurally and functionally, there are many peculiarities that differentiate the brain from all other organs. The brain is our connection to the world around us and by governing nervous system and higher function, any disturbance induces severe neurological and psychiatric disorders that can have a devastating effect on quality of life. Our understanding of the physiology and biochemistry of the brain has improved dramatically in the last two decades. In particular, the critical role of cations, including magnesium, has become evident, even if incompletely understood at a mechanistic level. The exact role and regulation of magnesium, in particular, remains elusive, largely because intracellular levels are so difficult to routinely quantify. Nonetheless, the importance of magnesium to normal central nervous system activity is self-evident given the complicated homeostatic mechanisms that maintain the concentration of this cation within strict limits essential for normal physiology and metabolism. There is also considerable accumulating evidence to suggest alterations to some brain functions in both normal and pathological conditions may be linked to alterations in local magnesium concentration. This book, containing chapters written by some of the foremost experts in the field of magnesium research, brings together the latest in experimental and clinical magnesium research as it relates to the central nervous system. It offers a complete and updated view of magnesiums involvement in central nervous system function and in so doing, brings together two main pillars of contemporary neuroscience research, namely providing an explanation for the molecular mechanisms involved in brain function, and emphasizing the connections between the molecular changes and behavior. It is the untiring efforts of those magnesium researchers who have dedicated their lives to unraveling the mysteries of magnesiums role in biological systems that has inspired the collation of this volume of work.

Download or read book Drug Repurposing in Cancer Therapy written by Kenneth K.W. To and published by Academic Press. This book was released on 2020-07-29 with total page 460 pages. Available in PDF, EPUB and Kindle. Book excerpt: Drug Repurposing in Cancer Therapy: Approaches and Applications provides comprehensive and updated information from experts in basic science research and clinical practice on how existing drugs can be repurposed for cancer treatment. The book summarizes successful stories that may assist researchers in the field to better design their studies for new repurposing projects. Sections discuss specific topics such as in silico prediction and high throughput screening of repurposed drugs, drug repurposing for overcoming chemoresistance and eradicating cancer stem cells, and clinical investigation on combination of repurposed drug and anticancer therapy. Cancer researchers, oncologists, pharmacologists and several members of biomedical field who are interested in learning more about the use of existing drugs for different purposes in cancer therapy will find this to be a valuable resource. - Presents a systematic and up-to-date collection of the research underpinning the various drug repurposing approaches for a quick, but in-depth understanding on current trends in drug repurposing research - Brings better understanding of the drug repurposing process in a holistic way, combining both basic and clinical sciences - Encompasses a collection of successful stories of drug repurposing for cancer therapy in different cancer types

Download or read book Drug Abuse Films written by and published by . This book was released on 1980 with total page 32 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Bad Pharma written by Ben Goldacre and published by Farrar, Straus and Giroux. This book was released on 2013-02-05 with total page 449 pages. Available in PDF, EPUB and Kindle. Book excerpt: We like to imagine that medicine is based on evidence and the results of fair testing and clinical trials. In reality, those tests and trials are often profoundly flawed. We like to imagine that doctors who write prescriptions for everything from antidepressants to cancer drugs to heart medication are familiar with the research literature about a drug, when in reality much of the research is hidden from them by drug companies. We like to imagine that doctors are impartially educated, when in reality much of their education is funded by the pharmaceutical industry. We like to imagine that regulators have some code of ethics and let only effective drugs onto the market, when in reality they approve useless drugs, with data on side effects casually withheld from doctors and patients. All these problems have been shielded from public scrutiny because they're too complex to capture in a sound bite. But Ben Goldacre shows that the true scale of this murderous disaster fully reveals itself only when the details are untangled. He believes we should all be able to understand precisely how data manipulation works and how research misconduct in the medical industry affects us on a global scale. With Goldacre's characteristic flair and a forensic attention to detail, Bad Pharma reveals a shockingly broken system and calls for regulation. This is the pharmaceutical industry as it has never been seen before.

Download or read book Marijuana As Medicine written by Institute of Medicine and published by National Academies Press. This book was released on 2000-12-30 with total page 216 pages. Available in PDF, EPUB and Kindle. Book excerpt: Some people suffer from chronic, debilitating disorders for which no conventional treatment brings relief. Can marijuana ease their symptoms? Would it be breaking the law to turn to marijuana as a medication? There are few sources of objective, scientifically sound advice for people in this situation. Most books about marijuana and medicine attempt to promote the views of advocates or opponents. To fill the gap between these extremes, authors Alison Mack and Janet Joy have extracted critical findings from a recent Institute of Medicine study on this important issue, interpreting them for a general audience. Marijuana As Medicine? provides patientsâ€"as well as the people who care for themâ€"with a foundation for making decisions about their own health care. This empowering volume examines several key points, including: Whether marijuana can relieve a variety of symptoms, including pain, muscle spasticity, nausea, and appetite loss. The dangers of smoking marijuana, as well as the effects of its active chemical components on the immune system and on psychological health. The potential use of marijuana-based medications on symptoms of AIDS, cancer, multiple sclerosis, and several other specific disorders, in comparison with existing treatments. Marijuana As Medicine? introduces readers to the active compounds in marijuana. These include the principal ingredient in Marinol, a legal medication. The authors also discuss the prospects for developing other drugs derived from marijuana's active ingredients. In addition to providing an up-to-date review of the science behind the medical marijuana debate, Mack and Joy also answer common questions about the legal status of marijuana, explaining the conflict between state and federal law regarding its medical use. Intended primarily as an aid to patients and caregivers, this book objectively presents critical information so that it can be used to make responsible health care decisions. Marijuana As Medicine? will also be a valuable resource for policymakers, health care providers, patient counselors, medical faculty and studentsâ€"in short, anyone who wants to learn more about this important issue.

Download or read book Treating Alcohol and Drug Problems in Psychotherapy Practice written by Arnold M. Washton and published by Guilford Publications. This book was released on 2022-11-11 with total page 314 pages. Available in PDF, EPUB and Kindle. Book excerpt: Providing a framework for treating substance use disorders (SUDs) in office-based psychotherapy, the second edition of this trusted work has been updated throughout and features two entirely new chapters. The authors show how clinicians from any background can leverage the therapeutic skills they already have to address clients' alcohol and drug problems competently and effectively. Vivid case examples demonstrate ways to engage clients at different stages of change; set collaborative treatment goals; address SUDs concurrently with other psychological problems; and interweave motivational, cognitive-behavioral, and other interventions, tailored to each individual's needs. Reproducible forms and handouts can be downloaded and printed in a convenient 8 1/2" x 11" size. New to This Edition *Chapter on evidence-based principles and interventions. *Chapter on moderation-focused alcohol treatment. *Revised throughout with current data, clinical techniques, and examples. *Reflects over 15 years of important changes in the field--increased demand for integrated treatment, the ongoing opioid crisis, the growth of harm reduction and medication-assisted treatments, and more.

Download or read book Learning to Live Drug Free written by and published by . This book was released on 1990 with total page 204 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Drug Toxicity written by Cam E. Vellotis and published by Nova Publishers. This book was released on 2008 with total page 350 pages. Available in PDF, EPUB and Kindle. Book excerpt: The systemic effects of a drug that are related to the overall level of the medication in the bloodstream. Drug toxicity may occur with overdosage of a medication, accumulation of the drug in the body over time or the inability of the patients body to eliminate the drug. This book presents recent and important research in the field.

Download or read book Bulletin of Pharmacy written by and published by . This book was released on 1922 with total page 624 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Journal of the House of Representatives of the United States written by United States. Congress. House and published by . This book was released on 2011 with total page 1668 pages. Available in PDF, EPUB and Kindle. Book excerpt: Some vols. include supplemental journals of "such proceedings of the sessions, as, during the time they were depending, were ordered to be kept secret, and respecting which the injunction of secrecy was afterwards taken off by the order of the House".

Download or read book Annual Report of the Board of Health of the Department of Health written by New York (N.Y.). Department of Health and published by . This book was released on 1904 with total page 556 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Utah Payroll Builder written by and published by . This book was released on 1917 with total page 786 pages. Available in PDF, EPUB and Kindle. Book excerpt: